Harvard Catalyst Profiles

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Aphidicolin

"Aphidicolin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An antiviral antibiotic produced by Cephalosporium aphidicola and other fungi. It inhibits the growth of eukaryotic cells and certain animal viruses by selectively inhibiting the cellular replication of DNA polymerase II or the viral-induced DNA polymerases. The drug may be useful for controlling excessive cell proliferation in patients with cancer, psoriasis or other dermatitis with little or no adverse effect upon non-multiplying cells.


This graph shows the total number of publications written about "Aphidicolin" by people in Harvard Catalyst Profiles by year, and whether "Aphidicolin" was a major or minor topic of these publication.
Bar chart showing 22 publications over 13 distinct years, with a maximum of 3 publications in 1990 and 1993
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.