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Stephen J Kohut, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DA047575 (BERGMAN, JACK) Jul 1, 2019 - Apr 30, 2024
    NIH/NIDA
    Neural, Cognitive and Abuse-Related Consequences of Chronic THC Exposure during Adolescence in Nonhuman Primates
    Role: Co-Principal Investigator
  2. R01DA048150 (KOHUT, STEPHEN JOHN) Apr 15, 2019 - Feb 29, 2024
    NIH/NIDA
    Synthetic Psychoactive Bath Salt Effects on Brain Activity and Behavior
    Role: Principal Investigator
  3. R01DA047130 (BOOTH, RAYMOND G.) Aug 1, 2018 - May 31, 2023
    NIH/NIDA
    Delineating the role of serotonin 5-HT2 receptors in opioid use disorders:Development of novel 5-HT2 modulators with translational studies in rodents andprimates
    Role: Co-Principal Investigator
  4. K01DA039306 (KOHUT, STEPHEN JOHN) Apr 1, 2015 - Mar 31, 2020
    NIH/NIDA
    Translational models of brain activation patterns during nicotine self-administration and reinstatement
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. de Moura FB, Barkin CE, Blough BE, Carroll FI, Mello NK, Kohut SJ. Effects of chronic treatment with bupropion on self-administration of nicotine + cocaine mixtures in nonhuman primates. Exp Clin Psychopharmacol. 2019 Dec 02. PMID: 31789555.
    Citations:    
  2. Bardo MT, Denehy ED, Hammerslag LR, Dwoskin LP, Blough BE, Landavazo A, Bergman J, Kohut SJ. Effects of methamphetamine isomers on d-methamphetamine self-administration and food-maintained responding in male rats. Psychopharmacology (Berl). 2019 Dec; 236(12):3557-3565. PMID: 31346628.
    Citations:    
  3. de Moura FB, Kohut SJ, Bergman J. Medications development for food-based and drug use disorders. Adv Pharmacol. 2019; 86:197-236. PMID: 31378252.
    Citations:    
  4. Kangas BD, Doyle RJ, Kohut SJ, Bergman J, Kaufman MJ. Effects of chronic cocaine self-administration and N-acetylcysteine on learning, cognitive flexibility, and reinstatement in nonhuman primates. Psychopharmacology (Berl). 2019 Jul; 236(7):2143-2153. PMID: 30877326.
    Citations:    
  5. Katz JL, Kohut SJ, Soto P. Vigilance demand and the effects of stimulant drugs in a five-choice reaction-time procedure in mice. Behav Pharmacol. 2018 12; 29(8):701-708. PMID: 30418959.
    Citations:    Fields:    
  6. Kohut SJ, Bergman J. Lorcaserin decreases the reinforcing effects of heroin, but not food, in rhesus monkeys. Eur J Pharmacol. 2018 Dec 05; 840:28-32. PMID: 30268662.
    Citations:    Fields:    Translation:Animals
  7. de Moura FB, Kohut SJ, Bergman J. Limited modulation of the abuse-related behavioral effects of d-methamphetamine by disulfiram. Exp Clin Psychopharmacol. 2018 Oct; 26(5):497-502. PMID: 29963872.
    Citations:    Fields:    Translation:Animals
  8. Jacobs DS, Barkin CE, Kohut MR, Bergman J, Kohut SJ. Effects of lorcaserin (Belviq®) on nicotine- and food-maintained responding in non-human primates. Drug Alcohol Depend. 2017 12 01; 181:94-101. PMID: 29040827.
    Citations:    Fields:    Translation:Animals
  9. Kohut SJ, Jacobs DS, Rothman RB, Partilla JS, Bergman J, Blough BE. Cocaine-like discriminative stimulus effects of "norepinephrine-preferring" monoamine releasers: time course and interaction studies in rhesus monkeys. Psychopharmacology (Berl). 2017 Dec; 234(23-24):3455-3465. PMID: 28889212.
    Citations: 1     Fields:    Translation:Animals
  10. Kohut SJ. Interactions between nicotine and drugs of abuse: a review of preclinical findings. Am J Drug Alcohol Abuse. 2017 03; 43(2):155-170. PMID: 27589579.
    Citations: 2     Fields:    Translation:HumansAnimals
  11. Jacobs DS, Kohut SJ, Jiang S, Nikas SP, Makriyannis A, Bergman J. Acute and chronic effects of cannabidiol on ??-tetrahydrocannabinol (??-THC)-induced disruption in stop signal task performance. Exp Clin Psychopharmacol. 2016 10; 24(5):320-330. PMID: 27690502.
    Citations:    Fields:    Translation:Animals
  12. Kohut SJ, Bergman J. Reinforcing effectiveness of nicotine in nonhuman primates: effects of nicotine dose and history of nicotine self-administration. Psychopharmacology (Berl). 2016 07; 233(13):2451-8. PMID: 27076210.
    Citations: 4     Fields:    Translation:Animals
  13. Desai RI, Sullivan KA, Kohut SJ, Bergman J. Influence of experimental history on nicotine self-administration in squirrel monkeys. Psychopharmacology (Berl). 2016 06; 233(12):2253-63. PMID: 27040402.
    Citations: 3     Fields:    Translation:Animals
  14. Kohut SJ, Bergman J, Blough BE. Effects of L-methamphetamine treatment on cocaine- and food-maintained behavior in rhesus monkeys. Psychopharmacology (Berl). 2016 Mar; 233(6):1067-75. PMID: 26713332.
    Citations: 3     Fields:    Translation:Animals
  15. Head RE, Kohut S, Caine SB, Bergman J. Obituary:Nancy K.Mello,Ph.D.(March 20,1935–November 25,2013). Drug Alcohol Depend. 2014 May 01; 138:255-6. PMID: 24829974.
    Citations:    Fields:    
  16. Kohut SJ, Hiranita T, Hong SK, Ebbs AL, Tronci V, Green J, Garcés-Ramírez L, Chun LE, Mereu M, Newman AH, Katz JL, Tanda G. Preference for distinct functional conformations of the dopamine transporter alters the relationship between subjective effects of cocaine and stimulation of mesolimbic dopamine. Biol Psychiatry. 2014 Nov 15; 76(10):802-9. PMID: 24853388.
    Citations: 13     Fields:    Translation:AnimalsCells
  17. Mello NK, Fivel PA, Kohut SJ, Caine SB. Anatabine significantly decreases nicotine self-administration. Exp Clin Psychopharmacol. 2014 Feb; 22(1):1-8. PMID: 24490707.
    Citations: 3     Fields:    Translation:Animals
  18. Mello NK, Fivel PA, Kohut SJ, Carroll FI. Effects of chronic varenicline treatment on nicotine, cocaine, and concurrent nicotine+cocaine self-administration. Neuropsychopharmacology. 2014 Apr; 39(5):1222-31. PMID: 24304823.
    Citations: 7     Fields:    Translation:Animals
  19. Hiranita T, Kohut SJ, Soto PL, Tanda G, Kopajtic TA, Katz JL. Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats. J Pharmacol Exp Ther. 2014 Jan; 348(1):174-91. PMID: 24194527.
    Citations: 22     Fields:    Translation:Animals
  20. Kohut SJ, Fivel PA, Mello NK. Differential effects of acute and chronic treatment with the a2-adrenergic agonist, lofexidine, on cocaine self-administration in rhesus monkeys. Drug Alcohol Depend. 2013 Dec 01; 133(2):593-9. PMID: 23998378.
    Citations: 6     Fields:    Translation:Animals
  21. Kohut SJ, Fivel PA, Blough BE, Rothman RB, Mello NK. Effects of methcathinone and 3-Cl-methcathinone (PAL-434) in cocaine discrimination or self-administration in rhesus monkeys. Int J Neuropsychopharmacol. 2013 Oct; 16(9):1985-98. PMID: 23768644.
    Citations: 7     Fields:    Translation:Animals
  22. Mello NK, Fivel PA, Kohut SJ. Effects of chronic buspirone treatment on nicotine and concurrent nicotine+cocaine self-administration. Neuropsychopharmacology. 2013 Jun; 38(7):1264-75. PMID: 23337868.
    Citations: 9     Fields:    Translation:Animals
  23. Mello NK, Fivel PA, Kohut SJ, Bergman J. Effects of chronic buspirone treatment on cocaine self-administration. Neuropsychopharmacology. 2013 Feb; 38(3):455-67. PMID: 23072835.
    Citations: 18     Fields:    Translation:Animals
  24. Kohut SJ, Decicco-Skinner KL, Johari S, Hurwitz ZE, Baumann MH, Riley AL. Differential modulation of cocaine's discriminative cue by repeated and variable stress exposure: relation to monoamine transporter levels. Neuropharmacology. 2012 Aug; 63(2):330-7. PMID: 22516586.
    Citations: 3     Fields:    Translation:Animals
  25. Hiranita T, Soto PL, Kohut SJ, Kopajtic T, Cao J, Newman AH, Tanda G, Katz JL. Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and s receptors. J Pharmacol Exp Ther. 2011 Nov; 339(2):662-77. PMID: 21859929.
    Citations: 35     Fields:    Translation:Animals
  26. Kohut SJ, Riley AL. The effects of home-cage access to a sweet solution on the discriminative stimulus effects of cocaine. Behav Pharmacol. 2010 May; 21(3):241-5. PMID: 20445440.
    Citations:    Fields:    Translation:Animals
  27. Freeman KB, Kearns DN, Kohut SJ, Riley AL. Strain differences in patterns of drug-intake during prolonged access to cocaine self-administration. Behav Neurosci. 2009 Feb; 123(1):156-64. PMID: 19170440.
    Citations: 7     Fields:    Translation:Animals
  28. Christensen CJ, Kohut SJ, Handler S, Silberberg A, Riley AL. Demand for food and cocaine in Fischer and Lewis rats. Behav Neurosci. 2009 Feb; 123(1):165-71. PMID: 19170441.
    Citations: 14     Fields:    Translation:Animals
  29. Kohut SJ, Roma PG, Davis CM, Zernig G, Saria A, Dominguez JM, Rice KC, Riley AL. The impact of early environmental rearing condition on the discriminative stimulus effects and Fos expression induced by cocaine in adult male and female rats. Psychopharmacology (Berl). 2009 Apr; 203(2):383-97. PMID: 18953528.
    Citations: 5     Fields:    Translation:Animals
  30. Kohut SJ, Ator NA. Novel discriminative stimulus effects of TPA023B, subtype-selective gamma-aminobutyric-acid(A)/benzodiazepine modulator: comparisons with zolpidem, lorazepam, and TPA023. Pharmacol Biochem Behav. 2008 Jul; 90(1):65-73. PMID: 18395780.
    Citations: 5     Fields:    Translation:Animals
  31. Roma PG, Davis CM, Kohut SJ, Huntsberry ME, Riley AL. Early maternal separation and sex differences in the aversive effects of amphetamine in adult rats. Physiol Behav. 2008 Mar 18; 93(4-5):897-904. PMID: 18230402.
    Citations: 11     Fields:    Translation:Animals
  32. Kohut SJ, Handler SL, Hertzbach RL, Riley AL. Schedule-induced polydipsia alters cocaine- but not ethanol-induced suppression of saccharin consumption. Drug Alcohol Depend. 2007 Nov 02; 91(1):18-25. PMID: 17548172.
    Citations: 1     Fields:    Translation:Animals
  33. Walker EA, Kohut SJ, Hass RW, Brown EK, Prabandham A, Lefever T. Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice. Neuropharmacology. 2005 Dec; 49(8):1210-9. PMID: 16165167.
    Citations: 6     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.