Harvard Catalyst Profiles

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Ronald H Goldstein, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. I01CX000908 (GOLDSTEIN, RONALD HOWARD) Jul 1, 2013 - Jun 30, 2019
    Tadalafil for Pulmonary Hypertension Associated with Chronic Lung Disease
    Role: Principal Investigator
  2. R01HL070182 (GOLDSTEIN, RONALD HOWARD) Aug 1, 2002 - Jul 31, 2007
    Regulation of Collagen Formation in Pulmonary Fibrosis
    Role: Principal Investigator
  3. R01HL066547 (GOLDSTEIN, RONALD HOWARD) Sep 29, 2000 - Aug 31, 2004
    Role: Principal Investigator
  4. P50HL056386 (GOLDSTEIN, RONALD HOWARD) Dec 1, 1996 - Jun 30, 2002
    Role: Principal Investigator
  5. P01HL046902 (NUGENT, MATTHEW A) Dec 3, 1991 - Nov 30, 2007
    Lung Connective Tissue-Responses to Injury And Repair
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Johnson SW, Finlay L, Mathai SC, Goldstein RH, Maron BA. Real-world use of inhaled treprostinil for lung disease-pulmonary hypertension: A protocol for patient evaluation and prescribing. Pulm Circ. 2022 Jul; 12(3):e12126. PMID: 36092795; PMCID: PMC9450844.
  2. Maron BA, Choudhary G, Goldstein RL, Garshick E, Jankowich M, Tucker TJS, LaCerda KA, Hattler B, Dempsey EC, Sadikot RT, Shapiro S, Rounds SI, Goldstein RH. Tadalafil for veterans with chronic obstructive pulmonary disease-pulmonary hypertension: A multicenter, placebo-controlled randomized trial. Pulm Circ. 2022 Jan; 12(1):e12043. PMID: 35506072; PMCID: PMC9053004.
    Citations: 2     
  3. Clark K, Goldstein R, Maron B, Breu AC. A Veteran Presenting With Chronic Progressive Dyspnea on Exertion. Fed Pract. 2020 Nov; 37(11):522-526. PMID: 33328718.
  4. Maron BA, Brittain EL, Hess E, Waldo SW, Barón AE, Huang S, Goldstein RH, Assad T, Wertheim BM, Alba GA, Leopold JA, Olschewski H, Galiè N, Simonneau G, Kovacs G, Tedford RJ, Humbert M, Choudhary G. Pulmonary vascular resistance and clinical outcomes in patients with pulmonary hypertension: a retrospective cohort study. Lancet Respir Med. 2020 09; 8(9):873-884. PMID: 32730752; PMCID: PMC8219057.
    Citations: 37     Fields:    Translation:Humans
  5. Maron BA, Hess E, Maddox TM, Opotowsky AR, Tedford RJ, Lahm T, Joynt KE, Kass DJ, Stephens T, Stanislawski MA, Swenson ER, Goldstein RH, Leopold JA, Zamanian RT, Elwing JM, Plomondon ME, Grunwald GK, Barón AE, Rumsfeld JS, Choudhary G. Association of Borderline Pulmonary Hypertension With Mortality and Hospitalization in a Large Patient Cohort: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program. Circulation. 2016 Mar 29; 133(13):1240-8. PMID: 26873944; PMCID: PMC4811678.
    Citations: 124     Fields:    Translation:Humans
  6. Berry NC, Manyoo A, Oldham WM, Stephens TE, Goldstein RH, Waxman AB, Tracy JA, Leary PJ, Leopold JA, Kinlay S, Opotowsky AR, Systrom DM, Maron BA. Protocol for exercise hemodynamic assessment: performing an invasive cardiopulmonary exercise test in clinical practice. Pulm Circ. 2015 Dec; 5(4):610-8. PMID: 26697168; PMCID: PMC4671735.
    Citations: 27     
  7. Maron BA, Goldstein RH, Rounds SI, Shapiro S, Jankowich M, Garshick E, Moy ML, Gagnon D, Choudhary G. Study design and rationale for investigating phosphodiesterase type 5 inhibition for the treatment of pulmonary hypertension due to chronic obstructive lung disease: the TADA-PHiLD (TADAlafil for Pulmonary Hypertension associated with chronic obstructive Lung Disease) trial. Pulm Circ. 2013 Dec; 3(4):889-97. PMID: 25006405.
    Citations: 4     
  8. Golan-Gerstl R, Wallach-Dayan SB, Zisman P, Cardoso WV, Goldstein RH, Breuer R. Cellular FLICE-like inhibitory protein deviates myofibroblast fas-induced apoptosis toward proliferation during lung fibrosis. Am J Respir Cell Mol Biol. 2012 Sep; 47(3):271-9. PMID: 22582174.
    Citations: 31     Fields:    Translation:AnimalsCells
  9. Yu J, Taylor L, Rich C, Toselli P, Stone P, Green D, Warburton R, Hill N, Goldstein R, Polgar P. Transgenic expression of an altered angiotensin type I AT1 receptor resulting in marked modulation of vascular type I collagen. J Cell Physiol. 2012 May; 227(5):2013-21. PMID: 21751211.
    Citations: 1     Fields:    Translation:AnimalsCells
  10. Brooks WW, Shen S, Conrad CH, Goldstein RH, Deng LL, Bing OH. Transcriptional changes associated with recovery from heart failure in the SHR. J Mol Cell Cardiol. 2010 Sep; 49(3):390-401. PMID: 20547165.
    Citations: 5     Fields:    Translation:AnimalsCells
  11. Brooks WW, Shen SS, Conrad CH, Goldstein RH, Bing OH. Transition from compensated hypertrophy to systolic heart failure in the spontaneously hypertensive rat: Structure, function, and transcript analysis. Genomics. 2010 Feb; 95(2):84-92. PMID: 20006699.
    Citations: 18     Fields:    Translation:AnimalsCells
  12. Kuang PP, Zhang XH, Rich CB, Foster JA, Subramanian M, Goldstein RH. Activation of elastin transcription by transforming growth factor-beta in human lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2007 Apr; 292(4):L944-52. PMID: 17209135.
    Citations: 38     Fields:    Translation:HumansCells
  13. Subramanian M, Kuang PP, Wei L, Rishikof DC, Liu H, Goldstein RH. Modulation of amino acid uptake by TGF-beta in lung myofibroblasts. J Cell Biochem. 2006 Sep 01; 99(1):71-8. PMID: 16598748.
    Citations: 1     Fields:    Translation:HumansCells
  14. Kuang PP, Joyce-Brady M, Zhang XH, Jean JC, Goldstein RH. Fibulin-5 gene expression in human lung fibroblasts is regulated by TGF-beta and phosphatidylinositol 3-kinase activity. Am J Physiol Cell Physiol. 2006 Dec; 291(6):C1412-21. PMID: 16837650.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  15. Serlin DM, Kuang PP, Subramanian M, O'Regan A, Li X, Berman JS, Goldstein RH. Interleukin-1beta induces osteopontin expression in pulmonary fibroblasts. J Cell Biochem. 2006 Feb 15; 97(3):519-29. PMID: 16211580.
    Citations: 13     Fields:    Translation:AnimalsCells
  16. Rishikof DC, Lucey EC, Kuang PP, Snider GL, Goldstein RH. Induction of the myofibroblast phenotype following elastolytic injury to mouse lung. Histochem Cell Biol. 2006 May; 125(5):527-34. PMID: 16328432.
    Citations: 6     Fields:    Translation:AnimalsCells
  17. Chen P, Marsilio E, Goldstein RH, Yannas IV, Spector M. Formation of lung alveolar-like structures in collagen-glycosaminoglycan scaffolds in vitro. Tissue Eng. 2005 Sep-Oct; 11(9-10):1436-48. PMID: 16259599.
    Citations: 19     Fields:    Translation:AnimalsCells
  18. Berk JL, Hatch CA, Morris SM, Stone PJ, Goldstein RH. Hypoxia suppresses elastin repair by rat lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2005 Dec; 289(6):L931-6. PMID: 16055482.
    Citations: 7     Fields:    Translation:AnimalsCells
  19. Kuang PP, Lucey E, Rishikof DC, Humphries DE, Bronsnick D, Goldstein RH. Engraftment of neonatal lung fibroblasts into the normal and elastase-injured lung. Am J Respir Cell Mol Biol. 2005 Oct; 33(4):371-7. PMID: 16037486; PMCID: PMC2715345.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  20. Kuang PP, Goldstein RH. Regulation of elastin gene transcription by proteasome dysfunction. Am J Physiol Cell Physiol. 2005 Sep; 289(3):C766-73. PMID: 15814588.
    Citations: 6     Fields:    Translation:AnimalsCells
  21. Rishikof DC, Kuang PP, Subramanian M, Goldstein RH. Methods for measuring type I collagen synthesis in vitro. Methods Mol Med. 2005; 117:129-40. PMID: 16118450.
    Citations:    Fields:    Translation:HumansCells
  22. Buczek-Thomas JA, Lucey EC, Stone PJ, Chu CL, Rich CB, Carreras I, Goldstein RH, Foster JA, Nugent MA. Elastase mediates the release of growth factors from lung in vivo. Am J Respir Cell Mol Biol. 2004 Sep; 31(3):344-50. PMID: 15191913.
    Citations: 21     Fields:    Translation:AnimalsCells
  23. Rishikof DC, Ricupero DA, Liu H, Goldstein RH. Phenylbutyrate decreases type I collagen production in human lung fibroblasts. J Cell Biochem. 2004 Mar 01; 91(4):740-8. PMID: 14991765.
    Citations: 16     Fields:    Translation:HumansCells
  24. Kuang PP, Goldstein RH, Liu Y, Rishikof DC, Jean JC, Joyce-Brady M. Coordinate expression of fibulin-5/DANCE and elastin during lung injury repair. Am J Physiol Lung Cell Mol Physiol. 2003 Nov; 285(5):L1147-52. PMID: 12909585.
    Citations: 19     Fields:    Translation:AnimalsCells
  25. Kuang PP, Goldstein RH. Regulation of elastin gene transcription by interleukin-1 beta-induced C/EBP beta isoforms. Am J Physiol Cell Physiol. 2003 Dec; 285(6):C1349-55. PMID: 12890646.
    Citations: 9     Fields:    Translation:AnimalsCells
  26. Lucey EC, Goldstein RH, Breuer R, Rexer BN, Ong DE, Snider GL. Retinoic acid does not affect alveolar septation in adult FVB mice with elastase-induced emphysema. Respiration. 2003 Mar-Apr; 70(2):200-5. PMID: 12740518.
    Citations: 12     Fields:    Translation:Animals
  27. Izbicki G, Or R, Christensen TG, Segel MJ, Fine A, Goldstein RH, Breuer R. Bleomycin-induced lung fibrosis in IL-4-overexpressing and knockout mice. Am J Physiol Lung Cell Mol Physiol. 2002 Nov; 283(5):L1110-6. PMID: 12376365.
    Citations: 11     Fields:    Translation:Animals
  28. Brooks WW, Bing OH, Gaasch WH, Karlinsky JB, Goldstein RH, Conrad CH. Comparison of contractile function of diaphragm and cardiac muscle in response to paired electrical stimulation. Comp Biochem Physiol A Mol Integr Physiol. 2002 Sep; 133(1):53-62. PMID: 12160872.
    Citations: 1     Fields:    Translation:Animals
  29. Tzurel A, Segel MJ, Or R, Goldstein RH, Breuer R. Halofuginone does not reduce fibrosis in bleomycin-induced lung injury. Life Sci. 2002 Aug 23; 71(14):1599-606. PMID: 12137906.
    Citations: 6     Fields:    Translation:AnimalsCells
  30. Kuang PP, Berk JL, Rishikof DC, Foster JA, Humphries DE, Ricupero DA, Goldstein RH. NF-kappaB induced by IL-1beta inhibits elastin transcription and myofibroblast phenotype. Am J Physiol Cell Physiol. 2002 Jul; 283(1):C58-65. PMID: 12055073.
    Citations: 14     Fields:    Translation:AnimalsCells
  31. Rishikof DC, Ricupero DA, Kuang PP, Liu H, Goldstein RH. Interleukin-4 regulates connective tissue growth factor expression in human lung fibroblasts. J Cell Biochem. 2002; 85(3):496-504. PMID: 11967989.
    Citations: 6     Fields:    Translation:HumansCells
  32. Lucey EC, Keane J, Kuang PP, Snider GL, Goldstein RH. Severity of elastase-induced emphysema is decreased in tumor necrosis factor-alpha and interleukin-1beta receptor-deficient mice. Lab Invest. 2002 Jan; 82(1):79-85. PMID: 11796828.
    Citations: 54     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.