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Ryan Carroll, M.D.

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My research and development interests combine investigations into the pathophysiology of severe and cerebral malaria, pediatric critical care capacity building, and appropriate medical technology development for low- and middle-income countries. I work with the MassGen Hospital for Children (MGHfC) divisions of Pediatric Global Health and Pediatric Critical Care, developing didactics and a robust training platform for domestic and international trainees, in addition to building pediatric critical care services in several global locations.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Olson KR, Nimkin K, Carroll RW, Stathatos N, Ordulu Z. Case 9-2021: A 16-Year-Old Boy with Headache, Abdominal Pain, and Hypertension. N Engl J Med. 2021 Mar 25; 384(12):1145-1155. PMID: 33761211.
    Citations:    Fields:    Translation:Humans
  2. Feldstein LR, Tenforde MW, Friedman KG, Newhams M, Rose EB, Dapul H, Soma VL, Maddux AB, Mourani PM, Bowens C, Maamari M, Hall MW, Riggs BJ, Giuliano JS, Singh AR, Li S, Kong M, Schuster JE, McLaughlin GE, Schwartz SP, Walker TC, Loftis LL, Hobbs CV, Halasa NB, Doymaz S, Babbitt CJ, Hume JR, Gertz SJ, Irby K, Clouser KN, Cvijanovich NZ, Bradford TT, Smith LS, Heidemann SM, Zackai SP, Wellnitz K, Nofziger RA, Horwitz SM, Carroll RW, Rowan CM, Tarquinio KM, Mack EH, Fitzgerald JC, Coates BM, Jackson AM, Young CC, Son MBF, Patel MM, Newburger JW, Randolph AG. Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19. JAMA. 2021 03 16; 325(11):1074-1087. PMID: 33625505.
    Citations: 2     Fields:    Translation:Humans
  3. LaRovere KL, Riggs BJ, Poussaint TY, Young CC, Newhams MM, Maamari M, Walker TC, Singh AR, Dapul H, Hobbs CV, McLaughlin GE, Son MBF, Maddux AB, Clouser KN, Rowan CM, McGuire JK, Fitzgerald JC, Gertz SJ, Shein SL, Munoz AC, Thomas NJ, Irby K, Levy ER, Staat MA, Tenforde MW, Feldstein LR, Halasa NB, Giuliano JS, Hall MW, Kong M, Carroll CL, Schuster JE, Doymaz S, Loftis LL, Tarquinio KM, Babbitt CJ, Nofziger RA, Kleinman LC, Keenaghan MA, Cvijanovich NZ, Spinella PC, Hume JR, Wellnitz K, Mack EH, Michelson KN, Flori HR, Patel MM, Randolph AG. Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome. JAMA Neurol. 2021 Mar 05. PMID: 33666649.
    Citations:    Fields:    
  4. Fernandes ND, Cummings BM, Naber CE, Salt MD, Lok J, Yager PH, Carroll RW. Adult COVID-19 Patients Cared For in a Pediatric ICU Embedded in a Regional Biothreat Center: Disease Severity and Outcomes. Health Secur. 2020 Dec 16. PMID: 33326301.
    Citations:    Fields:    
  5. Wiegand SB, Traeger L, Nguyen HK, Rouillard KR, Fischbach A, Zadek F, Ichinose F, Schoenfisch MH, Carroll RW, Bloch DB, Zapol WM. Antimicrobial effects of nitric oxide in murine models of Klebsiella pneumonia. Redox Biol. 2021 02; 39:101826. PMID: 33352464.
    Citations:    Fields:    
  6. Safaee Fakhr B, Wiegand SB, Pinciroli R, Gianni S, Morais CCA, Ikeda T, Miyazaki Y, Marutani E, Di Fenza R, Larson GM, Parcha V, Gibson LE, Chang MG, Arora P, Carroll RW, Kacmarek RM, Ichinose F, Barth WH, Kaimal A, Hohmann EL, Zapol WM, Berra L. High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 2020 12; 136(6):1109-1113. PMID: 32852324.
    Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
  7. Wiegand SB, Safaee Fakhr B, Carroll RW, Zapol WM, Kacmarek RM, Berra L. Rescue Treatment With High-Dose Gaseous Nitric Oxide in Spontaneously Breathing Patients With Severe Coronavirus Disease 2019. Crit Care Explor. 2020 Nov; 2(11):e0277. PMID: 33225304.
    Citations: 1     
  8. Gianni S, Morais CCA, Larson G, Pinciroli R, Carroll R, Yu B, Zapol WM, Berra L. Ideation and assessment of a nitric oxide delivery system for spontaneously breathing subjects. Nitric Oxide. 2020 11 01; 104-105:29-35. PMID: 32835810.
    Citations: 2     Fields:    
  9. Bartley BL, Gardner KJ, Spina S, Hurley BP, Campeau D, Berra L, Yonker LM, Carroll RW. High-Dose Inhaled Nitric Oxide as Adjunct Therapy in Cystic Fibrosis Targeting Burkholderia multivorans. Case Rep Pediatr. 2020; 2020:1536714. PMID: 32685229.
    Citations: 1     
  10. Fernandes ND, Chung E, Salt MD, Ejiofor B, Carroll RW, Kacmarek RM. Measured CPAP in a Noninvasive Pediatric Airway and Lung Model. Respir Care. 2021 Jan; 66(1):87-94. PMID: 32576707.
    Citations:    Fields:    Translation:Humans
  11. Krezanoski PJ, Santorino D, Agaba A, Dorsey G, Bangsberg DR, Carroll RW. How Are Insecticide-Treated Bednets Used in Ugandan Households? A Comprehensive Characterization of Bednet Adherence Using a Remote Monitor. Am J Trop Med Hyg. 2019 08; 101(2):404-411. PMID: 31287045.
    Citations: 2     Fields:    Translation:Humans
  12. Ejiofor BD, Carroll RW, Bortcosh W, Kacmarek RM. PEEP Generated by High-Flow Nasal Cannula in a Pediatric Model. Respir Care. 2019 Oct; 64(10):1240-1249. PMID: 31088986.
    Citations: 4     Fields:    Translation:Humans
  13. Cieslak TJ, Evans L, Kortepeter MG, Grindle A, Aigbivbalu L, Boulter K, Carroll RW, Cumplido S, Danforth AG, Fry C, Gaensbauer J, Hume JR, Husain A, Kelleher A, Kratochvil CJ, Kunrath C, Morgan JS, Schwedhelm MM, Shane AL, Tennill P, Yager PH, Davies HD. Perspectives on the Management of Children in a Biocontainment Unit: Report of the NETEC Pediatric Workgroup. Health Secur. 2019 Jan/Feb; 17(1):11-17. PMID: 30779612.
    Citations:    Fields:    Translation:HumansPHPublic Health
  14. Otani IM, Carroll RW, Yager P, Kroshinsky D, Murphy S, Hornick JL, Akin C, Castells M, Walter JE. Diffuse cutaneous mastocytosis with novel somatic KIT mutation K509I and association with tuberous sclerosis. Clin Case Rep. 2018 Sep; 6(9):1834-1840. PMID: 30214774.
    Citations: 2     
  15. Bennett DJ, Carroll RW, Kacmarek RM. Evaluation of a Low-Cost Bubble CPAP System Designed for Resource-Limited Settings. Respir Care. 2018 Apr; 63(4):395-403. PMID: 29382795.
    Citations: 4     Fields:    Translation:Humans
  16. Lee GQ, Bangsberg DR, Mo T, Lachowski C, Brumme CJ, Zhang W, Lima VD, Boum Y, Mwebesa BB, Muzoora C, Andia I, Mbalibulha Y, Kembabazi A, Carroll R, Siedner MJ, Haberer JE, Mocello AR, Kigozi SH, Hunt PW, Martin JN, Harrigan PR. Prevalence and clinical impacts of HIV-1 intersubtype recombinants in Uganda revealed by near-full-genome population and deep sequencing approaches. AIDS. 2017 11 13; 31(17):2345-2354. PMID: 28832407.
    Citations: 7     Fields:    Translation:HumansCells
  17. Bortcosh W, Siedner M, Carroll RW. Utility of the urine reagent strip leucocyte esterase assay for the diagnosis of meningitis in resource-limited settings: meta-analysis. Trop Med Int Health. 2017 09; 22(9):1072-1080. PMID: 28627004.
    Citations: 2     Fields:    Translation:HumansCells
  18. Carroll RW, Katz ML, Paul E, Jüppner H. Case 17-2017. A 14-Year-Old Boy with Acute Fear of Choking while Swallowing. N Engl J Med. 2017 06 08; 376(23):2266-2275. PMID: 28591527.
    Citations:    Fields:    Translation:HumansCells
  19. Mwanga-Amumpaire J, Carroll RW, Baudin E, Kemigisha E, Nampijja D, Mworozi K, Santorino D, Nyehangane D, Nathan DI, De Beaudrap P, Etard JF, Feelisch M, Fernandez BO, Berssenbrugge A, Bangsberg D, Bloch KD, Boum Y, Zapol WM. Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial. Open Forum Infect Dis. 2015 Sep; 2(3):ofv111. PMID: 26309894.
    Citations: 14     
  20. Sundararajan R, Mwanga-Amumpaire J, Adrama H, Tumuhairwe J, Mbabazi S, Mworozi K, Carroll R, Bangsberg D, Boum Y, Ware NC. Sociocultural and structural factors contributing to delays in treatment for children with severe malaria: a qualitative study in southwestern Uganda. Am J Trop Med Hyg. 2015 May; 92(5):933-940. PMID: 25802438.
    Citations: 15     Fields:    Translation:Humans
  21. DePasse JW, Carroll R, Ippolito A, Yost A, Santorino D, Chu Z, Olson KR. Less noise, more hacking: how to deploy principles from MIT's hacking medicine to accelerate health care. Int J Technol Assess Health Care. 2014 Jul; 30(3):260-4. PMID: 25096225.
    Citations: 13     Fields:    Translation:Humans
  22. Rogers DJ, Collins C, Carroll R, Yager P, Cummings B, Raol N, Setlur J, Maturo S, Tremblay S, Quinones E, Noviski N, Hartnick CJ. Operation airway: the first sustainable, multidisciplinary, pediatric airway surgical mission. Ann Otol Rhinol Laryngol. 2014 Oct; 123(10):726-33. PMID: 24835243.
    Citations: 1     Fields:    Translation:Humans
  23. Bergmark B, Bergmark R, Beaudrap PD, Boum Y, Mwanga-Amumpaire J, Carroll R, Zapol W. Inhaled nitric oxide and cerebral malaria: basis of a strategy for buying time for pharmacotherapy. Pediatr Infect Dis J. 2012 Dec; 31(12):e250-4. PMID: 22760538.
    Citations: 6     Fields:    Translation:Humans
  24. Ackerman HC, Carroll RW, Casals-Pascual C. A better biomarker for cerebral malaria: in the eye of the beheld?*. Crit Care Med. 2012 Mar; 40(3):1018-20. PMID: 22343865.
    Citations:    Fields:    Translation:Animals
  25. Carroll RW, Wainwright MS, Kim KY, Kidambi T, Gómez ND, Taylor T, Haldar K. A rapid murine coma and behavior scale for quantitative assessment of murine cerebral malaria. PLoS One. 2010 Oct 01; 5(10). PMID: 20957049.
    Citations: 44     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.