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Sebastian Unizony, M.D.



Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Stone JH, Spotswood H, Unizony SH, Aringer M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Spiera R, Bao M. New-onset versus relapsing giant cell arteritis treated with tocilizumab: 3-year results from a randomized controlled trial and extension. Rheumatology (Oxford). 2022 07 06; 61(7):2915-2922. PMID: 34718434; PMCID: PMC9258533.
    Citations: 1     Fields:    Translation:Humans
  2. Bouffard MA, Prasad S, Unizony S, Costello F. Does Tocilizumab Influence Ophthalmic Outcomes in Giant Cell Arteritis? J Neuroophthalmol. 2022 06 01; 42(2):173-179. PMID: 35482901.
    Citations:    Fields:    Translation:Humans
  3. Cid MC, Unizony SH, Blockmans D, Brouwer E, Dagna L, Dasgupta B, Hellmich B, Molloy E, Salvarani C, Trapnell BC, Warrington KJ, Wicks I, Samant M, Zhou T, Pupim L, Paolini JF. Efficacy and safety of mavrilimumab in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial. Ann Rheum Dis. 2022 05; 81(5):653-661. PMID: 35264321; PMCID: PMC8995812.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  4. Patel NJ, Fu X, Zhang Y, Unizony SH, Wallace ZS, Choi HK, Stone JH. The Effects of Treatment on Body Mass Index in Giant Cell Arteritis: A Post Hoc Analysis of the GiACTA Trial. Rheumatol Ther. 2022 Apr; 9(2):497-508. PMID: 34954809; PMCID: PMC8964534.
  5. Matza MA, Fernandes AD, Stone JH, Unizony SH. Reply. Arthritis Care Res (Hoboken). 2021 07; 73(7):1059-1060. PMID: 33161642.
    Citations: 1     Fields:    
  6. Matza MA, Fernandes AD, Stone JH, Unizony SH. Reply. Arthritis Care Res (Hoboken). 2021 07; 73(7):1057-1058. PMID: 32961035.
    Citations:    Fields:    
  7. Matza MA, Fernandes AD, Stone JH, Unizony SH. Ustekinumab for the Treatment of Giant Cell Arteritis. Arthritis Care Res (Hoboken). 2021 06; 73(6):893-897. PMID: 32248659.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  8. Unizony SH, Bao M, Han J, Luder Y, Pavlov A, Stone JH. Treatment failure in giant cell arteritis. Ann Rheum Dis. 2021 11; 80(11):1467-1474. PMID: 34049857; PMCID: PMC8522464.
    Citations: 4     Fields:    Translation:Humans
  9. Spiera R, Unizony SH, Bao M, Luder Y, Han J, Pavlov A, Stone JH. Tocilizumab vs placebo for the treatment of giant cell arteritis with polymyalgia rheumatica symptoms, cranial symptoms or both in a randomized trial. Semin Arthritis Rheum. 2021 04; 51(2):469-476. PMID: 33784598.
    Citations: 3     Fields:    Translation:Humans
  10. Unizony SH, Kelly HR, O'Donnell EK, Sadigh S. Case 3-2021: A 48-Year-Old Man with Transient Vision Loss. N Engl J Med. 2021 Jan 28; 384(4):363-372. PMID: 33503346.
    Citations:    Fields:    Translation:Humans
  11. Unizony S, McCulley TJ, Spiera R, Pei J, Sidiropoulos PN, Best JH, Birchwood C, Pavlov A, Stone JH. Clinical outcomes of patients with giant cell arteritis treated with tocilizumab in real-world clinical practice: decreased incidence of new visual manifestations. Arthritis Res Ther. 2021 01 06; 23(1):8. PMID: 33407817.
    Citations: 9     Fields:    Translation:Humans
  12. Stone JH, Frigault MJ, Serling-Boyd NJ, Fernandes AD, Harvey L, Foulkes AS, Horick NK, Healy BC, Shah R, Bensaci AM, Woolley AE, Nikiforow S, Lin N, Sagar M, Schrager H, Huckins DS, Axelrod M, Pincus MD, Fleisher J, Sacks CA, Dougan M, North CM, Halvorsen YD, Thurber TK, Dagher Z, Scherer A, Wallwork RS, Kim AY, Schoenfeld S, Sen P, Neilan TG, Perugino CA, Unizony SH, Collier DS, Matza MA, Yinh JM, Bowman KA, Meyerowitz E, Zafar A, Drobni ZD, Bolster MB, Kohler M, D'Silva KM, Dau J, Lockwood MM, Cubbison C, Weber BN, Mansour MK. Efficacy of Tocilizumab in Patients Hospitalized with Covid-19. N Engl J Med. 2020 12 10; 383(24):2333-2344. PMID: 33085857; PMCID: PMC7646626.
    Citations: 510     Fields:    Translation:Humans
  13. Schmidt WA, Dasgupta B, Luqmani R, Unizony SH, Blockmans D, Lai Z, Kurrasch RH, Lazic I, Brown K, Rao R. A Multicentre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Sirukumab in the Treatment of Giant Cell Arteritis. Rheumatol Ther. 2020 Dec; 7(4):793-810. PMID: 32844378.
    Citations: 8     
  14. Best JH, Kong AM, Unizony S, Tran O, Michalska M. Risk of Potential Glucocorticoid-Related Adverse Events in Patients with Giant Cell Arteritis: Results from a USA-Based Electronic Health Records Database. Rheumatol Ther. 2019 Dec; 6(4):599-610. PMID: 31656021; PMCID: PMC6858477.
    Citations: 1     
  15. Tawakol A, Unizony S, Osborne MT, Massarotti E, Giles JT. Evolving Use of Molecular Imaging in Research and in Practice. Arthritis Rheumatol. 2019 08; 71(8):1207-1210. PMID: 30835948; PMCID: PMC6945743.
    Citations: 2     Fields:    Translation:Humans
  16. Stone JH, Tuckwell K, Dimonaco S, Klearman M, Aringer M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Schulze-Koops H, Schett G, Spiera R, Unizony SH, Collinson N. Glucocorticoid Dosages and Acute-Phase Reactant Levels at Giant Cell Arteritis Flare in a Randomized Trial of Tocilizumab. Arthritis Rheumatol. 2019 08; 71(8):1329-1338. PMID: 30835950; PMCID: PMC6772126.
    Citations: 21     Fields:    Translation:Humans
  17. Das AS, Conway SE, Unizony SH, Bouffard MA, Rost NS, Venna N. Pearls & Oy-sters: Neuro-Sweet disease presenting as ischemic stroke and aseptic meningitis. Neurology. 2018 12 04; 91(23):e2197-e2199. PMID: 30510029; PMCID: PMC6282232.
    Citations: 2     Fields:    Translation:Humans
  18. Unizony S, Kermani TA. IL-6 Blockade and its Therapeutic Success in Giant Cell Arteritis. J Neuroophthalmol. 2018 12; 38(4):551-558. PMID: 30199509.
    Citations: 1     Fields:    Translation:Humans
  19. Prieto-González S, Terrades-García N, Corbera-Bellalta M, Planas-Rigol E, Miyabe C, Alba MA, Ponce A, Tavera-Bahillo I, Murgia G, Espígol-Frigolé G, Marco-Hernández J, Hernández-Rodríguez J, García-Martínez A, Unizony SH, Cid MC. Serum osteopontin: a biomarker of disease activity and predictor of relapsing course in patients with giant cell arteritis. Potential clinical usefulness in tocilizumab-treated patients. RMD Open. 2017; 3(2):e000570. PMID: 29299342; PMCID: PMC5743901.
    Citations: 13     
  20. Stone JH, Tuckwell K, Dimonaco S, Klearman M, Aringer M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Schett G, Schulze-Koops H, Spiera R, Unizony SH, Collinson N. Trial of Tocilizumab in Giant-Cell Arteritis. N Engl J Med. 2017 07 27; 377(4):317-328. PMID: 28745999.
    Citations: 239     Fields:    Translation:HumansCTClinical Trials
  21. Wallace ZS, Miloslavsky EM, Cascino M, Unizony SH, Lu N, Hoffman GS, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera R, St Clair EW, Specks U, Brunetta P, Choi HK, Stone JH. Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab on Body Composition During Induction Treatment of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Care Res (Hoboken). 2017 07; 69(7):1004-1010. PMID: 27696762.
    Citations: 6     Fields:    Translation:Humans
  22. Wallace ZS, Lu N, Miloslavsky E, Unizony S, Stone JH, Choi HK. Nationwide Trends in Hospitalizations and In-Hospital Mortality in Granulomatosis With Polyangiitis (Wegener's). Arthritis Care Res (Hoboken). 2017 06; 69(6):915-921. PMID: 27389595.
    Citations: 12     Fields:    Translation:Humans
  23. Unizony S, Lu N, Tomasson G, Zhang Y, Merkel PA, Stone JH, Antonio Aviña-Zubieta J, Choi HK. Temporal Trends of Venous Thromboembolism Risk Before and After Diagnosis of Giant Cell Arteritis. Arthritis Rheumatol. 2017 01; 69(1):176-184. PMID: 28029234.
    Citations: 2     Fields:    Translation:Humans
  24. Miyabe C, Miyabe Y, Strle K, Kim ND, Stone JH, Luster AD, Unizony S. An expanded population of pathogenic regulatory T cells in giant cell arteritis is abrogated by IL-6 blockade therapy. Ann Rheum Dis. 2017 May; 76(5):898-905. PMID: 27927642; PMCID: PMC5744591.
    Citations: 30     Fields:    Translation:HumansCells
  25. Miloslavsky EM, Lu N, Unizony S, Choi HK, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Fervenza F, Monach PA, Specks U, Stone JH. Myeloperoxidase-Antineutrophil Cytoplasmic Antibody (ANCA)-Positive and ANCA-Negative Patients With Granulomatosis With Polyangiitis (Wegener's): Distinct Patient Subsets. Arthritis Rheumatol. 2016 12; 68(12):2945-2952. PMID: 27428559; PMCID: PMC5541999.
    Citations: 16     Fields:    Translation:Humans
  26. Tuckwell K, Collinson N, Dimonaco S, Klearman M, Blockmans D, Brouwer E, Cid MC, Dasgupta B, Rech J, Salvarani C, Unizony SH, Stone JH. Newly diagnosed vs. relapsing giant cell arteritis: Baseline data from the GiACTA trial. Semin Arthritis Rheum. 2017 04; 46(5):657-664. PMID: 27998620.
    Citations: 21     Fields:    Translation:Humans
  27. Keer N, Hershfield M, Caskey T, Unizony S. Novel compound heterozygous variants in CECR1 gene associated with childhood onset polyarteritis nodosa and deficiency of ADA2. Rheumatology (Oxford). 2016 06; 55(6):1145-7. PMID: 27069017.
    Citations: 6     Fields:    Translation:Humans
  28. Unizony S, Villarreal M, Miloslavsky EM, Lu N, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, Kallenberg CM, St Clair EW, Ikle D, Tchao NK, Ding L, Brunetta P, Choi HK, Monach PA, Fervenza F, Stone JH, Specks U. Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type. Ann Rheum Dis. 2016 Jun; 75(6):1166-9. PMID: 26621483; PMCID: PMC4908815.
    Citations: 54     Fields:    Translation:Humans
  29. Wallace ZS, Lu N, Unizony S, Stone JH, Choi HK. Improved survival in granulomatosis with polyangiitis: A general population-based study. Semin Arthritis Rheum. 2016 Feb; 45(4):483-9. PMID: 26323883; PMCID: PMC5009368.
    Citations: 20     Fields:    Translation:Humans
  30. Menendez ME, Lu N, Unizony S, Choi HK, Ring D. Surgical site infection in hand surgery. Int Orthop. 2015 Nov; 39(11):2191-8. PMID: 26156713.
    Citations: 8     Fields:    Translation:Humans
  31. Uchiyama E, Faez S, Nasir H, Unizony SH, Plenge R, Papaliodis GN, Sobrin L. Accuracy of the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) as a research tool for identification of patients with uveitis and scleritis. Ophthalmic Epidemiol. 2015 Apr; 22(2):139-41. PMID: 25777314.
    Citations: 3     Fields:    Translation:Humans
  32. Unizony SH, Kim ND, Hoang MP. Case Records of the Mass General Hospital. Case 7-2015: A 25-year-old man with oral ulcers, rash, and odynophagia. N Engl J Med. 2015 Feb 26; 372(9):864-72. PMID: 25714165.
    Citations: 1     Fields:    Translation:Humans
  33. Unizony S, Menendez ME, Rastalsky N, Stone JH. Inpatient complications in patients with giant cell arteritis: decreased mortality and increased risk of thromboembolism, delirium and adrenal insufficiency. Rheumatology (Oxford). 2015 Aug; 54(8):1360-8. PMID: 25667435.
    Citations: 7     Fields:    Translation:Humans
  34. Unizony S, Lim N, Phippard DJ, Carey VJ, Miloslavsky EM, Tchao NK, Iklé D, Asare AL, Merkel PA, Monach PA, Seo P, St Clair EW, Langford CA, Spiera R, Hoffman GS, Kallenberg CG, Specks U, Stone JH. Peripheral CD5+ B cells in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheumatol. 2015 Feb; 67(2):535-44. PMID: 25332071; PMCID: PMC4497572.
    Citations: 11     Fields:    Translation:HumansCells
  35. Miloslavsky EM, Stone JH, Unizony SH. Challenging mimickers of primary systemic vasculitis. Rheum Dis Clin North Am. 2015; 41(1):141-60, ix. PMID: 25399945.
    Citations: 4     Fields:    Translation:Humans
  36. Unizony S. 10. Mechanistic and imaging substudies in GiACTA. Rheumatology (Oxford). 2014 May; 53 Suppl 2:i6. PMID: 25079162.
  37. Faez S, Lobo AM, Unizony SH, Stone JH, Papaliodis GN, Sobrin L. Ocular inflammatory disease in patients with polymyalgia rheumatica: A case series and review of the literature. Clin Rheumatol. 2016 Jan; 35(1):251-8. PMID: 24696366.
    Citations: 2     Fields:    Translation:Humans
  38. Miloslavsky E, Unizony S. The heart in vasculitis. Rheum Dis Clin North Am. 2014 Feb; 40(1):11-26. PMID: 24268007.
    Citations: 14     Fields:    Translation:Humans
  39. Unizony SH, Dasgupta B, Fisheleva E, Rowell L, Schett G, Spiera R, Zwerina J, Harari O, Stone JH. Design of the tocilizumab in giant cell arteritis trial. Int J Rheumatol. 2013; 2013:912562. PMID: 23653652.
    Citations: 27     
  40. Arvikar SL, Collier DS, Fisher MC, Unizony S, Cohen GL, McHugh G, Kawai T, Strle K, Steere AC. Clinical correlations with Porphyromonas gingivalis antibody responses in patients with early rheumatoid arthritis. Arthritis Res Ther. 2013; 15(5):R109. PMID: 24017968.
    Citations: 27     Fields:    Translation:HumansCells
  41. Unizony S, Stone JH, Stone JR. New treatment strategies in large-vessel vasculitis. Curr Opin Rheumatol. 2013 Jan; 25(1):3-9. PMID: 23114585.
    Citations: 19     Fields:    Translation:Humans
  42. Unizony S, Arias-Urdaneta L, Miloslavsky E, Arvikar S, Khosroshahi A, Keroack B, Stone JR, Stone JH. Tocilizumab for the treatment of large-vessel vasculitis (giant cell arteritis, Takayasu arteritis) and polymyalgia rheumatica. Arthritis Care Res (Hoboken). 2012 Nov; 64(11):1720-9. PMID: 22674883.
    Citations: 75     Fields:    Translation:Humans
  43. Khosroshahi A, Carruthers MN, Deshpande V, Unizony S, Bloch DB, Stone JH. Rituximab for the treatment of IgG4-related disease: lessons from 10 consecutive patients. Medicine (Baltimore). 2012 Jan; 91(1):57-66. PMID: 22210556.
    Citations: 141     Fields:    Translation:HumansCTClinical Trials
  44. Hariri LP, Unizony S, Stone J, Mino-Kenudson M, Sharma A, Matsubara O, Mark EJ. Acute fibrinous and organizing pneumonia in systemic lupus erythematosus: a case report and review of the literature. Pathol Int. 2010 Nov; 60(11):755-9. PMID: 20946526.
    Citations: 23     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.