Harvard Catalyst Profiles

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Gwo-Shu Mary Lee, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chen YS, Lai CP, Chen C, Lee GB. Isolation and recovery of extracellular vesicles using optically-induced dielectrophoresis on an integrated microfluidic platform. Lab Chip. 2021 Mar 17. PMID: 33730143.
    Citations:    Fields:    
  2. Bakouny Z, Braun DA, Shukla SA, Pan W, Gao X, Hou Y, Flaifel A, Tang S, Bosma-Moody A, He MX, Vokes N, Nyman J, Xie W, Nassar AH, Abou Alaiwi S, Flippot R, Bouchard G, Steinharter JA, Nuzzo PV, Ficial M, Sant'Angelo M, Forman J, Berchuck JE, Dudani S, Bi K, Park J, Camp S, Sticco-Ivins M, Hirsch L, Baca SC, Wind-Rotolo M, Ross-Macdonald P, Sun M, Lee GM, Chang SL, Wei XX, McGregor BA, Harshman LC, Genovese G, Ellis L, Pomerantz M, Hirsch MS, Freedman ML, Atkins MB, Wu CJ, Ho TH, Linehan WM, McDermott DF, Heng DYC, Viswanathan SR, Signoretti S, Van Allen EM, Choueiri TK. Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma. Nat Commun. 2021 02 05; 12(1):808. PMID: 33547292.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  3. Pan W, Zhang Z, Kimball H, Qu F, Berlind K, Stopsack KH, Lee GM, Choueiri TK, Kantoff PW. Abiraterone Acetate Induces CREB1 Phosphorylation and Enhances the Function of the CBP-p300 Complex, Leading to Resistance in Prostate Cancer Cells. Clin Cancer Res. 2021 Apr 01; 27(7):2087-2099. PMID: 33495313.
    Citations:    Fields:    
  4. Fang YL, Wang CH, Chen YS, Chien CC, Kuo FC, You HL, Lee MS, Lee GB. An integrated microfluidic system for early detection of sepsis-inducing bacteria. Lab Chip. 2021 01 07; 21(1):113-121. PMID: 33232424.
    Citations:    Fields:    
  5. Nuzzo PV, Berchuck JE, Korthauer K, Spisak S, Nassar AH, Alaiwi SA, Chakravarthy A, Shen SY, Bakouny Z, Boccardo F, Steinharter J, Bouchard G, Curran CR, Pan W, Baca SC, Seo JH, Lee GM, Michaelson MD, Chang SL, Waikar SS, Sonpavde G, Irizarry RA, Pomerantz M, De Carvalho DD, Choueiri TK, Freedman ML. Author Correction: Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nat Med. 2020 Oct; 26(10):1663. PMID: 32895574.
    Citations: 1     Fields:    
  6. Pomerantz MM, Qiu X, Zhu Y, Takeda DY, Pan W, Baca SC, Gusev A, Korthauer KD, Severson TM, Ha G, Viswanathan SR, Seo JH, Nguyen HM, Zhang B, Pasaniuc B, Giambartolomei C, Alaiwi SA, Bell CA, O'Connor EP, Chabot MS, Stillman DR, Lis R, Font-Tello A, Li L, Cejas P, Bergman AM, Sanders J, van der Poel HG, Gayther SA, Lawrenson K, Fonseca MAS, Reddy J, Corona RI, Martovetsky G, Egan B, Choueiri T, Ellis L, Garraway IP, Lee GM, Corey E, Long HW, Zwart W, Freedman ML. Prostate cancer reactivates developmental epigenomic programs during metastatic progression. Nat Genet. 2020 08; 52(8):790-799. PMID: 32690948.
    Citations: 5     Fields:    Translation:HumansCells
  7. Nuzzo PV, Berchuck JE, Korthauer K, Spisak S, Nassar AH, Abou Alaiwi S, Chakravarthy A, Shen SY, Bakouny Z, Boccardo F, Steinharter J, Bouchard G, Curran CR, Pan W, Baca SC, Seo JH, Lee GM, Michaelson MD, Chang SL, Waikar SS, Sonpavde G, Irizarry RA, Pomerantz M, De Carvalho DD, Choueiri TK, Freedman ML. Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nat Med. 2020 07; 26(7):1041-1043. PMID: 32572266.
    Citations: 5     Fields:    Translation:HumansCells
  8. Lasseter K, Nassar AH, Hamieh L, Berchuck JE, Nuzzo PV, Korthauer K, Shinagare AB, Ogorek B, McKay R, Thorner AR, Lee GM, Braun DA, Bhatt RS, Freedman M, Choueiri TK, Kwiatkowski DJ. Plasma cell-free DNA variant analysis compared with methylated DNA analysis in renal cell carcinoma. Genet Med. 2020 08; 22(8):1366-1373. PMID: 32341571.
    Citations: 3     Fields:    
  9. Ma YD, Li KH, Chen YH, Lee YM, Chou ST, Lai YY, Huang PC, Ma HP, Lee GB. A sample-to-answer, portable platform for rapid detection of pathogens with a smartphone interface. Lab Chip. 2019 11 21; 19(22):3804-3814. PMID: 31620745.
    Citations: 12     Fields:    Translation:Cells
  10. Chen YS, Ma YD, Chen C, Shiesh SC, Lee GB. An integrated microfluidic system for on-chip enrichment and quantification of circulating extracellular vesicles from whole blood. Lab Chip. 2019 10 07; 19(19):3305-3315. PMID: 31495861.
    Citations: 2     Fields:    Translation:HumansCells
  11. Chen YS, Chung KC, Huang WY, Lee WB, Fu CY, Wang CH, Lee GB. Generating digital drug cocktails via optical manipulation of drug-containing particles and photo-patterning of hydrogels. Lab Chip. 2019 05 14; 19(10):1764-1771. PMID: 30942234.
    Citations:    Fields:    Translation:HumansCells
  12. Chen YH, Pulikkathodi AK, Ma YD, Wang YL, Lee GB. A microfluidic platform integrated with field-effect transistors for enumeration of circulating tumor cells. Lab Chip. 2019 02 12; 19(4):618-625. PMID: 30644487.
    Citations: 2     Fields:    Translation:HumansCells
  13. Cheng HL, Fu CY, Kuo WC, Chen YW, Chen YS, Lee YM, Li KH, Chen C, Ma HP, Huang PC, Wang YL, Lee GB. Detecting miRNA biomarkers from extracellular vesicles for cardiovascular disease with a microfluidic system. Lab Chip. 2018 09 26; 18(19):2917-2925. PMID: 30118128.
    Citations: 4     Fields:    Translation:HumansCells
  14. Xie W, Stopsack KH, Drouin SJ, Fu H, Pomerantz MM, Mucci LA, Lee GM, Kantoff PW. Association of genetic variation of the six gene prognostic model for castration-resistant prostate cancer with survival. Prostate. 2019 01; 79(1):73-80. PMID: 30141208.
    Citations: 2     Fields:    Translation:Humans
  15. Pulikkathodi AK, Sarangadharan I, Chen YH, Lee GY, Chyi JI, Lee GB, Wang YL. Dynamic monitoring of transmembrane potential changes: a study of ion channels using an electrical double layer-gated FET biosensor. Lab Chip. 2018 03 27; 18(7):1047-1056. PMID: 29488525.
    Citations: 3     Fields:    Translation:HumansCells
  16. Sun T, Du SY, Armenia J, Qu F, Fan J, Wang X, Fei T, Komura K, Liu SX, Lee GM, Kantoff PW. Expression of lncRNA MIR222HG co-transcribed from the miR-221/222 gene promoter facilitates the development of castration-resistant prostate cancer. Oncogenesis. 2018 Mar 13; 7(3):30. PMID: 29540675.
    Citations: 11     
  17. Harshman LC, Werner L, Tripathi A, Wang X, Maughan BL, Antonarakis ES, Nakabayashi M, McKay R, Pomerantz M, Mucci LA, Taplin ME, Sweeney CJ, Lee GM, Kantoff PW. The impact of statin use on the efficacy of abiraterone acetate in patients with castration-resistant prostate cancer. Prostate. 2017 May; 77(13):1303-1311. PMID: 28762529.
    Citations: 5     Fields:    Translation:HumansCells
  18. Qu F, Xie W, Nakabayashi M, Zhang H, Jeong SH, Wang X, Komura K, Sweeney CJ, Sartor O, Lee GM, Kantoff PW. Association of AR-V7 and Prostate-Specific Antigen RNA Levels in Blood with Efficacy of Abiraterone Acetate and Enzalutamide Treatment in Men with Prostate Cancer. Clin Cancer Res. 2017 Feb 01; 23(3):726-734. PMID: 27489290.
    Citations: 36     Fields:    Translation:Humans
  19. Xie W, Drouin S, Nakabayashi M, Pomerantz M, Lee GS, Kantoff PW, Sharifi N. A Genetic Variation of SOD2 Does Not Determine Duration of Response to Androgen Deprivation Therapy for Prostate Cancer. Prostate. 2016 10; 76(14):1338-41. PMID: 27325180.
    Citations:    Fields:    Translation:Humans
  20. Komura K, Jeong SH, Hinohara K, Qu F, Wang X, Hiraki M, Azuma H, Lee GS, Kantoff PW, Sweeney CJ. Resistance to docetaxel in prostate cancer is associated with androgen receptor activation and loss of KDM5D expression. Proc Natl Acad Sci U S A. 2016 May 31; 113(22):6259-64. PMID: 27185910.
    Citations: 32     Fields:    Translation:HumansCells
  21. Chan JM, Darke AK, Penney KL, Tangen CM, Goodman PJ, Lee GM, Sun T, Peisch S, Tinianow AM, Rae JM, Klein EA, Thompson IM, Kantoff PW, Mucci LA. Selenium- or Vitamin E-Related Gene Variants, Interaction with Supplementation, and Risk of High-Grade Prostate Cancer in SELECT. Cancer Epidemiol Biomarkers Prev. 2016 07; 25(7):1050-1058. PMID: 27197287.
    Citations: 10     Fields:    Translation:Humans
  22. Börnigen D, Tyekucheva S, Wang X, Rider JR, Lee GS, Mucci LA, Sweeney C, Huttenhower C. Computational Reconstruction of NF?B Pathway Interaction Mechanisms during Prostate Cancer. PLoS Comput Biol. 2016 Apr; 12(4):e1004820. PMID: 27078000.
    Citations: 5     Fields:    Translation:HumansCells
  23. Xie W, Yang M, Chan J, Sun T, Mucci LA, Penney KL, Lee GS, Kantoff PW. Association of genetic variations of selenoprotein genes, plasma selenium levels, and prostate cancer aggressiveness at diagnosis. Prostate. 2016 May; 76(7):691-9. PMID: 26847995.
    Citations: 5     Fields:    Translation:Humans
  24. Wang X, Harshman LC, Xie W, Nakabayashi M, Qu F, Pomerantz MM, Lee GS, Kantoff PW. Association of SLCO2B1 Genotypes With Time to Progression and Overall Survival in Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer. J Clin Oncol. 2016 Feb 01; 34(4):352-9. PMID: 26668348.
    Citations: 10     Fields:    Translation:Humans
  25. Wang X, Huang Y, Christie A, Bowden M, Lee GS, Kantoff PW, Sweeney CJ. Cabozantinib Inhibits Abiraterone's Upregulation of IGFIR Phosphorylation and Enhances Its Anti-Prostate Cancer Activity. Clin Cancer Res. 2015 Dec 15; 21(24):5578-87. PMID: 26289068.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  26. Harshman LC, Wang X, Nakabayashi M, Xie W, Valenca L, Werner L, Yu Y, Kantoff AM, Sweeney CJ, Mucci LA, Pomerantz M, Lee GS, Kantoff PW. Statin Use at the Time of Initiation of Androgen Deprivation Therapy and Time to Progression in Patients With Hormone-Sensitive Prostate Cancer. JAMA Oncol. 2015 Jul; 1(4):495-504. PMID: 26181260.
    Citations: 36     Fields:    Translation:HumansCells
  27. Sun T, McKay R, Lee GS, Kantoff P. The role of miRNAs in prostate cancer. Eur Urol. 2015 Oct; 68(4):589-90. PMID: 25577717.
    Citations: 4     Fields:    Translation:Humans
  28. Sun T, Ye H, Wu CL, Lee GS, Kantoff PW. Emerging players in prostate cancer: long non-coding RNAs. Am J Clin Exp Urol. 2014; 2(4):294-9. PMID: 25606575.
    Citations: 7     
  29. Hsieh CL, Fei T, Chen Y, Li T, Gao Y, Wang X, Sun T, Sweeney CJ, Lee GS, Chen S, Balk SP, Liu XS, Brown M, Kantoff PW. Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation. Proc Natl Acad Sci U S A. 2014 May 20; 111(20):7319-24. PMID: 24778216.
    Citations: 121     Fields:    Translation:HumansAnimalsCells
  30. Lohr JG, Adalsteinsson VA, Cibulskis K, Choudhury AD, Rosenberg M, Cruz-Gordillo P, Francis JM, Zhang CZ, Shalek AK, Satija R, Trombetta JJ, Lu D, Tallapragada N, Tahirova N, Kim S, Blumenstiel B, Sougnez C, Lowe A, Wong B, Auclair D, Van Allen EM, Nakabayashi M, Lis RT, Lee GS, Li T, Chabot MS, Ly A, Taplin ME, Clancy TE, Loda M, Regev A, Meyerson M, Hahn WC, Kantoff PW, Golub TR, Getz G, Boehm JS, Love JC. Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nat Biotechnol. 2014 May; 32(5):479-84. PMID: 24752078.
    Citations: 221     Fields:    Translation:HumansCells
  31. Yao X, Choudhury AD, Yamanaka YJ, Adalsteinsson VA, Gierahn TM, Williamson CA, Lamb CR, Taplin ME, Nakabayashi M, Chabot MS, Li T, Lee GS, Boehm JS, Kantoff PW, Hahn WC, Wittrup KD, Love JC. Functional analysis of single cells identifies a rare subset of circulating tumor cells with malignant traits. Integr Biol (Camb). 2014 Apr; 6(4):388-98. PMID: 24522233.
    Citations: 15     Fields:    Translation:HumansCells
  32. Ou CH, Yang WH, Tsai HW, Lee TJ, Chen SY, Huang SC, Chang YY, Lee GB, Lin XZ. Partial nephrectomy without renal ischemia using an electromagnetic thermal surgery system in a porcine model. Urology. 2013 May; 81(5):1101-7. PMID: 23465149.
    Citations: 1     Fields:    Translation:Animals
  33. Schutz FA, Pomerantz MM, Gray KP, Atkins MB, Rosenberg JE, Hirsch MS, McDermott DF, Lampron ME, Lee GS, Signoretti S, Kantoff PW, Freedman ML, Choueiri TK. Single nucleotide polymorphisms and risk of recurrence of renal-cell carcinoma: a cohort study. Lancet Oncol. 2013 Jan; 14(1):81-7. PMID: 23219378.
    Citations: 25     Fields:    Translation:Humans
  34. Ross RW, Galsky MD, Scher HI, Magidson J, Wassmann K, Lee GS, Katz L, Subudhi SK, Anand A, Fleisher M, Kantoff PW, Oh WK. A whole-blood RNA transcript-based prognostic model in men with castration-resistant prostate cancer: a prospective study. Lancet Oncol. 2012 Nov; 13(11):1105-13. PMID: 23059047.
    Citations: 47     Fields:    Translation:Humans
  35. Nguyen HC, Xie W, Yang M, Hsieh CL, Drouin S, Lee GS, Kantoff PW. Expression differences of circulating microRNAs in metastatic castration resistant prostate cancer and low-risk, localized prostate cancer. Prostate. 2013 Mar; 73(4):346-54. PMID: 22887127.
    Citations: 101     Fields:    Translation:Humans
  36. Tsai CY, Lu SL, Hu CW, Yeh CS, Lee GB, Lei HY. Size-dependent attenuation of TLR9 signaling by gold nanoparticles in macrophages. J Immunol. 2012 Jan 01; 188(1):68-76. PMID: 22156340.
    Citations: 35     Fields:    Translation:AnimalsCells
  37. Sun T, Yang M, Chen S, Balk S, Pomerantz M, Hsieh CL, Brown M, Lee GM, Kantoff PW. The altered expression of MiR-221/-222 and MiR-23b/-27b is associated with the development of human castration resistant prostate cancer. Prostate. 2012 Jul 01; 72(10):1093-103. PMID: 22127852.
    Citations: 47     Fields:    Translation:HumansCells
  38. Sun T, Oh WK, Jacobus S, Regan M, Pomerantz M, Freedman ML, Lee GS, Kantoff PW. The impact of common genetic variations in genes of the sex hormone metabolic pathways on steroid hormone levels and prostate cancer aggressiveness. Cancer Prev Res (Phila). 2011 Dec; 4(12):2044-50. PMID: 21900597.
    Citations: 10     Fields:    Translation:Humans
  39. Kamath AF, Lee GC, Sheth NP, Nelson CL, Garino JP, Israelite CL. Prospective results of uncemented tantalum monoblock tibia in total knee arthroplasty: minimum 5-year follow-up in patients younger than 55 years. J Arthroplasty. 2011 Dec; 26(8):1390-5. PMID: 21872424.
    Citations: 15     Fields:    Translation:Humans
  40. Yang M, Xie W, Mostaghel E, Nakabayashi M, Werner L, Sun T, Pomerantz M, Freedman M, Ross R, Regan M, Sharifi N, Figg WD, Balk S, Brown M, Taplin ME, Oh WK, Lee GS, Kantoff PW. SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer. J Clin Oncol. 2011 Jun 20; 29(18):2565-73. PMID: 21606417.
    Citations: 59     Fields:    Translation:Humans
  41. Misra D, Xie W, Regan MM, Ross RW, Lee GS, Germain D, Kantoff PW, Oh WK. Germline CAG repeat length of the androgen receptor and time to progression in patients with prostate cancer treated with androgen deprivation therapy. BJU Int. 2011 Oct; 108(7):1086-91. PMID: 21410629.
    Citations: 2     Fields:    Translation:HumansCells
  42. Pomerantz MM, Werner L, Xie W, Regan MM, Lee GS, Sun T, Evan C, Petrozziello G, Nakabayashi M, Oh WK, Kantoff PW, Freedman ML. Association of prostate cancer risk Loci with disease aggressiveness and prostate cancer-specific mortality. Cancer Prev Res (Phila). 2011 May; 4(5):719-28. PMID: 21367958.
    Citations: 21     Fields:    Translation:Humans
  43. Sun T, Lee GS, Oh WK, Pomerantz M, Yang M, Xie W, Freedman ML, Kantoff PW. Single-nucleotide polymorphisms in p53 pathway and aggressiveness of prostate cancer in a Caucasian population. Clin Cancer Res. 2010 Nov 01; 16(21):5244-51. PMID: 20855462.
    Citations: 16     Fields:    Translation:HumansCells
  44. Sun T, Lee GS, Werner L, Pomerantz M, Oh WK, Kantoff PW, Freedman ML. Inherited variations in AR, ESR1, and ESR2 genes are not associated with prostate cancer aggressiveness or with efficacy of androgen deprivation therapy. Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1871-8. PMID: 20615892.
    Citations: 10     Fields:    Translation:Humans
  45. Sun T, Yang M, Kantoff P, Lee GS. Role of microRNA-221/-222 in cancer development and progression. . 2009 Aug; 8(15):2315-6. PMID: 19625765.
    Citations: 15     Translation:Humans
  46. Penney KL, Salinas CA, Pomerantz M, Schumacher FR, Beckwith CA, Lee GS, Oh WK, Sartor O, Ostrander EA, Kurth T, Ma J, Mucci L, Stanford JL, Kantoff PW, Hunter DJ, Stampfer MJ, Freedman ML. Evaluation of 8q24 and 17q risk loci and prostate cancer mortality. Clin Cancer Res. 2009 May 01; 15(9):3223-30. PMID: 19366828.
    Citations: 27     Fields:    Translation:HumansCells
  47. Sun T, Wang Q, Balk S, Brown M, Lee GS, Kantoff P. The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines. Cancer Res. 2009 Apr 15; 69(8):3356-63. PMID: 19351832.
    Citations: 100     Fields:    Translation:HumansCells
  48. Sher DJ, Mantzoros C, Jacobus S, Regan MM, Lee GS, Oh WK. Absence of relationship between steroid hormone levels and prostate cancer tumor grade. Urology. 2009 Feb; 73(2):356-61; discussion 361-2. PMID: 19036418.
    Citations: 10     Fields:    Translation:Humans
  49. Sher DJ, Oh WK, Jacobus S, Regan MM, Lee GS, Mantzoros C. Relationship between serum adiponectin and prostate cancer grade. Prostate. 2008 Oct 01; 68(14):1592-8. PMID: 18646046.
    Citations: 20     Fields:    Translation:Humans
  50. Bao BY, Chuang BF, Wang Q, Sartor O, Balk SP, Brown M, Kantoff PW, Lee GS. Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes. Prostate. 2008 Jun 01; 68(8):839-48. PMID: 18302198.
    Citations: 27     Fields:    Translation:HumansCells
  51. Cushner FD, Lee GC, Scuderi GR, Arsht SJ, Scott WN. Blood loss management in high-risk patients undergoing total knee arthroplasty: a comparison of two techniques. J Knee Surg. 2006 Oct; 19(4):249-53. PMID: 17080646.
    Citations: 5     Fields:    Translation:Humans
  52. Chang YH, Lee GB, Huang FC, Chen YY, Lin JL. Integrated polymerase chain reaction chips utilizing digital microfluidics. Biomed Microdevices. 2006 Sep; 8(3):215-25. PMID: 16718406.
    Citations: 31     Fields:    Translation:Cells
  53. Lee GC, Cushner FD, Vigoritta V, Scuderi GR, Insall JN, Scott WN. Evaluation of the anterior cruciate ligament integrity and degenerative arthritic patterns in patients undergoing total knee arthroplasty. J Arthroplasty. 2005 Jan; 20(1):59-65. PMID: 15660061.
    Citations: 19     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.