Harvard Catalyst Profiles

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Samantha A. Spencer, M.D.

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selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Spencer SA, Suárez-Pozos E, Soto-Verdugo J, Wang H, Afshari FS, Li G, Manam S, Yasuda D, Ortega A, Lister JA, Ishii S, Zhang Y, Fuss B. Lysophosphatidic acid signaling via LPA6 : A negative modulator of developmental oligodendrocyte maturation. J Neurochem. 2022 12; 163(6):478-499. PMID: 36153691; PMCID: PMC9772207.
    Citations:    Fields:    Translation:HumansAnimalsCells
  2. Mahan ST, Miller PE, Kasser JR, Spencer SA. Prospective Evaluation of Tarsal Coalition Excision Show Significant Improvements in Pain and Function. J Pediatr Orthop. 2021 Oct 01; 41(9):e828-e832. PMID: 34411051.
    Citations: 1     Fields:    Translation:Humans
  3. Wu M, Zheng ET, Anderson ME, Miller PE, Spencer SA, Heyworth BE. Surgical Treatment of Solitary Periarticular Osteochondromas About the Knee in Pediatric and Adolescent Patients: Complications and Functional Outcomes. J Bone Joint Surg Am. 2021 07 21; 103(14):1276-1283. PMID: 34029267.
    Citations: 1     Fields:    Translation:Humans
  4. Savarirayan R, Tunkel DE, Sterni LM, Bober MB, Cho TJ, Goldberg MJ, Hoover-Fong J, Irving M, Kamps SE, Mackenzie WG, Raggio C, Spencer SA, Bompadre V, White KK. Best practice guidelines in managing the craniofacial aspects of skeletal dysplasia. Orphanet J Rare Dis. 2021 01 14; 16(1):31. PMID: 33446226; PMCID: PMC7809733.
    Citations: 3     Fields:    Translation:Humans
  5. Petratou K, Spencer SA, Kelsh RN, Lister JA. The MITF paralog tfec is required in neural crest development for fate specification of the iridophore lineage from a multipotent pigment cell progenitor. PLoS One. 2021; 16(1):e0244794. PMID: 33439865.
    Citations: 13     Fields:    Translation:AnimalsCells
  6. Jones KM, Corey KC, Garza-Mayers AC, Spencer SA, Mulliken JB, Chewning RH, Liang MG. Classification of lower extremity venous malformations and risk of knee involvement: A retrospective cohort study. J Am Acad Dermatol. 2021 12; 85(6):1480-1485. PMID: 33421482.
    Citations: 1     Fields:    Translation:Humans
  7. Cohen LL, Shore BJ, Miller PE, Troy MJ, Mahan ST, Kasser JR, Spencer SA, Hedequist DJ, Heyworth BE, Glotzbecker MP. Epiphysiodesis for Leg Length Discrepancy: A Cost Analysis of Drill Versus Screw Technique. J Surg Orthop Adv. 2021; 30(3):181-184. PMID: 34591010.
    Citations:    Fields:    Translation:Humans
  8. Torous VF, Simpson RW, Balani JP, Baras AS, Berman MA, Birdsong GG, Giannico GA, Paner GP, Pettus JR, Sessions Z, Sirintrapun SJ, Srigley JR, Spencer S. College of American Pathologists Cancer Protocols: From Optimizing Cancer Patient Care to Facilitating Interoperable Reporting and Downstream Data Use. JCO Clin Cancer Inform. 2021 01; 5:47-55. PMID: 33439728; PMCID: PMC8140812.
    Citations: 3     Fields:    Translation:Humans
  9. Spencer SA, Sorger JI. Orthopedic issues in vascular anomalies. Semin Pediatr Surg. 2020 Oct; 29(5):150973. PMID: 33069292.
    Citations: 1     Fields:    Translation:Humans
  10. Sinagoga KL, Larimer-Picciani AM, George SM, Spencer SA, Lister JA, Gross JM. Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure. Development. 2020 07 13; 147(21). PMID: 32541011; PMCID: PMC7375471.
    Citations: 5     Fields:    Translation:HumansAnimals
  11. White KK, Bober MB, Cho TJ, Goldberg MJ, Hoover-Fong J, Irving M, Kamps SE, Mackenzie WG, Raggio C, Spencer SA, Bompadre V, Savarirayan R. Best practice guidelines for management of spinal disorders in skeletal dysplasia. Orphanet J Rare Dis. 2020 06 24; 15(1):161. PMID: 32580780; PMCID: PMC7313125.
    Citations: 3     Fields:    Translation:Humans
  12. Wang KK, Glenn RL, Adams DM, Alomari AI, Al-Ibraheemi A, Anderson ME, Chaudry G, Fishman SJ, Greene AK, Shaikh R, Trenor CC, Kozakewich HP, Spencer SA. Surgical Management of Fibroadipose Vascular Anomaly of the Lower Extremities. J Pediatr Orthop. 2020 Mar; 40(3):e227-e236. PMID: 31181028.
    Citations: 4     Fields:    Translation:Humans
  13. Spencer SA, Suárez-Pozos E, Escalante M, Myo YP, Fuss B. Sodium-Calcium Exchangers of the SLC8 Family in Oligodendrocytes: Functional Properties in Health and Disease. Neurochem Res. 2020 Jun; 45(6):1287-1297. PMID: 31927687.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  14. Cheung K, Taghinia AH, Sood RF, Alomari AI, Spencer SA, Al-Ibraheemi A, Kozakewich HPW, Chaudry G, Greene AK, Mulliken JB, Trenor CC, Fishman SJ, Upton J. Fibroadipose Vascular Anomaly in the Upper Extremity: A Distinct Entity With Characteristic Clinical, Radiological, and Histopathological Findings. J Hand Surg Am. 2020 Jan; 45(1):68.e1-68.e13. PMID: 31279623.
    Citations: 4     Fields:    Translation:Humans
  15. Reis J, Alomari AI, Trenor CC, Adams DM, Fishman SJ, Spencer SA, Shaikh R, Lillis AP, Surnedi MK, Chaudry G. Pulmonary thromboembolic events in patients with congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and spinal/skeletal abnormalities and Klippel-Trénaunay syndrome. J Vasc Surg Venous Lymphat Disord. 2018 07; 6(4):511-516. PMID: 29909856.
    Citations: 8     Fields:    Translation:Humans
  16. Uller W, El-Sobky S, Alomari AI, Fishman SJ, Spencer SA, Taghinia AH, Chaudry G. Preoperative Embolization of Venous Malformations Using n-Butyl Cyanoacrylate. Vasc Endovascular Surg. 2018 May; 52(4):269-274. PMID: 29544400.
    Citations: 4     Fields:    Translation:Humans
  17. Mahan ST, Prete VI, Spencer SA, Kasser JR, Bixby SD. Subtalar Coalitions: Does the Morphology of the Subtalar Joint Involvement Influence Outcomes After Coalition Excision? J Foot Ankle Surg. 2017 Jul - Aug; 56(4):797-801. PMID: 28633780.
    Citations: 2     Fields:    Translation:Humans
  18. Shore BJ, DiMauro JP, Spence DD, Miller PE, Glotzbecker MP, Spencer S, Hedequist D. Uniplanar Versus Taylor Spatial Frame External Fixation For Pediatric Diaphyseal Tibia Fractures: A Comparison of Cost and Complications. J Pediatr Orthop. 2016 Dec; 36(8):821-828. PMID: 26090976.
    Citations: 5     Fields:    Translation:Humans
  19. Stern CM, Pepin MJ, Stoler JM, Kramer DE, Spencer SA, Stein CJ. Musculoskeletal Conditions in a Pediatric Population with Ehlers-Danlos Syndrome. J Pediatr. 2017 02; 181:261-266. PMID: 27908650.
    Citations: 16     Fields:    Translation:Humans
  20. Allar BG, Hedequist DJ, Miller PE, Glotzbecker MP, Spencer SA, Shore BJ. Treatment outcomes after insufficiency femoral diaphyseal fractures in nonambulatory children. J Pediatr Orthop B. 2016 Jul; 25(4):331-7. PMID: 27135220.
    Citations: 1     Fields:    Translation:Humans
  21. Mahan ST, Lierhaus AM, Spencer SA, Kasser JR. Treatment dilemma in multiple metatarsal fractures: when to operate? J Pediatr Orthop B. 2016 Jul; 25(4):354-60. PMID: 26990060.
    Citations: 1     Fields:    Translation:Humans
  22. Shaikh R, Alomari AI, Kerr CL, Miller P, Spencer SA. Cryoablation in fibro-adipose vascular anomaly (FAVA): a minimally invasive treatment option. Pediatr Radiol. 2016 Jul; 46(8):1179-86. PMID: 26902298.
    Citations: 15     Fields:    Translation:Humans
  23. White KK, Savarirayan R, Goldberg MJ, MacKenzie W, Bompadre V, Bober MB, Cho TJ, Hoover-Fong J, Parnell SE, Raggio C, Spencer SA, Campbell JW, Rapoport DM, Kifle Y, Blackledge M. Response: "Best practices in the evaluation and treatment of foramen magnum stenosis in achondroplasia during infancy" and "Is there a correlation between sleep disordered breathing and foramen magnum stenosis in children with achondroplasia?". Am J Med Genet A. 2016 Apr; 170A(4):1101-3. PMID: 26754314.
    Citations:    Fields:    Translation:Humans
  24. Hedequist D, Spencer S, Richards BS, Fishman S, Alomari A. Surgical Treatment of Spinal Deformity in Patients With CLOVES Syndrome: A Report of 4 Cases. J Pediatr Orthop. 2015 Oct-Nov; 35(7):682-6. PMID: 25393573.
    Citations: 1     Fields:    Translation:Humans
  25. White KK, Bompadre V, Goldberg MJ, Bober MB, Campbell JW, Cho TJ, Hoover-Fong J, Mackenzie W, Parnell SE, Raggio C, Rapoport DM, Spencer SA, Savarirayan R. Best practices in the evaluation and treatment of foramen magnum stenosis in achondroplasia during infancy. Am J Med Genet A. 2016 Jan; 170A(1):42-51. PMID: 26394886.
    Citations: 19     Fields:    Translation:Humans
  26. Mahan ST, Spencer SA, Vezeridis PS, Kasser JR. Patient-reported Outcomes of Tarsal Coalitions Treated With Surgical Excision. J Pediatr Orthop. 2015 Sep; 35(6):583-8. PMID: 25333904.
    Citations: 7     Fields:    Translation:Humans
  27. Mahan ST, Hoellwarth JS, Spencer SA, Kramer DE, Hedequist DJ, Kasser JR. Likelihood of surgery in isolated pediatric fifth metatarsal fractures. J Pediatr Orthop. 2015 Apr-May; 35(3):296-302. PMID: 24992354.
    Citations: 1     Fields:    Translation:Humans
  28. Luks VL, Kamitaki N, Vivero MP, Uller W, Rab R, Bovée JV, Rialon KL, Guevara CJ, Alomari AI, Greene AK, Fishman SJ, Kozakewich HP, Maclellan RA, Mulliken JB, Rahbar R, Spencer SA, Trenor CC, Upton J, Zurakowski D, Perkins JA, Kirsh A, Bennett JT, Dobyns WB, Kurek KC, Warman ML, McCarroll SA, Murillo R. Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA. J Pediatr. 2015 Apr; 166(4):1048-54.e1-5. PMID: 25681199; PMCID: PMC4498659.
    Citations: 153     Fields:    Translation:Humans
  29. Simpson RW, Berman MA, Foulis PR, Divaris DX, Birdsong GG, Mirza J, Moldwin R, Spencer S, Srigley JR, Fitzgibbons PL. Cancer biomarkers: the role of structured data reporting. Arch Pathol Lab Med. 2015 May; 139(5):587-93. PMID: 25275812.
    Citations: 14     Fields:    Translation:Humans
  30. Upasani VV, Matheney TH, Spencer SA, Kim YJ, Millis MB, Kasser JR. Complications after modified Dunn osteotomy for the treatment of adolescent slipped capital femoral epiphysis. J Pediatr Orthop. 2014 Oct-Nov; 34(7):661-7. PMID: 25210939.
    Citations: 30     Fields:    Translation:Humans
  31. Mahan ST, Spencer SA, Kasser JR. Satisfactory patient-based outcomes after surgical treatment for idiopathic clubfoot: includes surgeon's individualized technique. J Pediatr Orthop. 2014 Sep; 34(6):631-8. PMID: 24787304.
    Citations: 4     Fields:    Translation:Humans
  32. Spencer SA, Sorger J. Orthopedic issues in vascular anomalies. Semin Pediatr Surg. 2014 Aug; 23(4):227-32. PMID: 25241103.
    Citations: 5     Fields:    Translation:Humans
  33. Alomari AI, Spencer SA, Arnold RW, Chaudry G, Kasser JR, Burrows PE, Govender P, Padua HM, Dillon B, Upton J, Taghinia AH, Fishman SJ, Mulliken JB, Fevurly RD, Greene AK, Landrigan-Ossar M, Paltiel HJ, Trenor CC, Kozakewich HP. Fibro-adipose vascular anomaly: clinical-radiologic-pathologic features of a newly delineated disorder of the extremity. J Pediatr Orthop. 2014 Jan; 34(1):109-17. PMID: 24322574.
    Citations: 23     Fields:    Translation:Humans
  34. Glotzbecker MP, Estroff JA, Curtis TA, Kalish LA, Spencer SA, Parad RB, Kasser JR, Mahan ST. Prospective evaluation of a prenatal sonographic clubfoot classification system. Fetal Diagn Ther. 2013; 34(4):236-40. PMID: 24135764.
    Citations: 2     Fields:    Translation:Humans
  35. Fitzgibbons PL, Lazar AJ, Spencer S. Introducing new College of American Pathologists reporting templates for cancer biomarkers. Arch Pathol Lab Med. 2014 Feb; 138(2):157-8. PMID: 23808404.
    Citations: 3     Fields:    Translation:Humans
  36. Li Y, Spencer SA, Hedequist D. Proximal tibial osteotomy and Taylor Spatial Frame application for correction of tibia vara in morbidly obese adolescents. J Pediatr Orthop. 2013 Apr-May; 33(3):276-81. PMID: 23482263.
    Citations: 6     Fields:    Translation:Humans
  37. Hoellwarth JS, Mahan ST, Spencer SA. Painful pes planovalgus: an uncommon pediatric orthopedic presentation of Charcot-Marie-Tooth disease. J Pediatr Orthop B. 2012 Sep; 21(5):428-33. PMID: 22744235.
    Citations: 1     Fields:    Translation:Humans
  38. Kurek KC, Luks VL, Ayturk UM, Alomari AI, Fishman SJ, Spencer SA, Mulliken JB, Bowen ME, Yamamoto GL, Kozakewich HP, Warman ML. Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome. Am J Hum Genet. 2012 Jun 08; 90(6):1108-15. PMID: 22658544.
    Citations: 169     Fields:    Translation:HumansCells
  39. Glotzbecker MP, Kocher MS, Sundel RP, Shore BJ, Spencer SA, Kasser JR. Primary lyme arthritis of the pediatric hip. J Pediatr Orthop. 2011 Oct-Nov; 31(7):787-90. PMID: 21926878.
    Citations: 4     Fields:    Translation:Humans
  40. Tsai A, Chaudry G, Spencer S, Kasser JR, Alomari AI. Misdiagnosis of knee venous malformation as juvenile idiopathic arthritis. J Pediatr Orthop. 2011 Sep; 31(6):683-90. PMID: 21841446.
    Citations: 3     Fields:    Translation:Humans
  41. Smith JT, Curtis TA, Spencer S, Kasser JR, Mahan ST. Complications of talus fractures in children. J Pediatr Orthop. 2010 Dec; 30(8):779-84. PMID: 21102201.
    Citations: 12     Fields:    Translation:Humans
  42. Glotzbecker MP, Estroff JA, Spencer SA, Bosley JC, Parad RB, Kasser JR, Mahan ST. Prenatally diagnosed clubfeet: comparing ultrasonographic severity with objective clinical outcomes. J Pediatr Orthop. 2010 Sep; 30(6):606-11. PMID: 20733428.
    Citations: 9     Fields:    Translation:Humans
  43. Ziebarth K, Zilkens C, Spencer S, Leunig M, Ganz R, Kim YJ. Capital realignment for moderate and severe SCFE using a modified Dunn procedure. Clin Orthop Relat Res. 2009 Mar; 467(3):704-16. PMID: 19142692; PMCID: PMC2635450.
    Citations: 87     Fields:    Translation:Humans
  44. Rebello G, Spencer S, Millis MB, Kim YJ. Surgical dislocation in the management of pediatric and adolescent hip deformity. Clin Orthop Relat Res. 2009 Mar; 467(3):724-31. PMID: 19002743; PMCID: PMC2635463.
    Citations: 26     Fields:    Translation:Humans
  45. Spencer S, Millis MB, Kim YJ. Early results of treatment of hip impingement syndrome in slipped capital femoral epiphysis and pistol grip deformity of the femoral head-neck junction using the surgical dislocation technique. J Pediatr Orthop. 2006 May-Jun; 26(3):281-5. PMID: 16670535.
    Citations: 31     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.