Harvard Catalyst Profiles

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Thomas McCoy Roberts, Ph.D.

Concepts

This page shows the publications Thomas Roberts has written about Polyomavirus.
Connection Strength

2.144
  1. Polyoma small T antigen triggers cell death via mitotic catastrophe. Oncogene. 2015 May 07; 34(19):2483-92.
    View in: PubMed
    Score: 0.533
  2. Transgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma. J Virol. 2011 Jun; 85(11):5581-92.
    View in: PubMed
    Score: 0.424
  3. Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer. Virology. 2009 Feb 20; 384(2):304-16.
    View in: PubMed
    Score: 0.361
  4. Transformation by Polyomavirus Middle T Antigen Involves a Unique Bimodal Interaction with the Hippo Effector YAP. J Virol. 2016 08 15; 90(16):7032-7045.
    View in: PubMed
    Score: 0.154
  5. Association of Polyomavirus middle tumor antigen with phospholipase C-gamma 1. J Biol Chem. 1995 May 26; 270(21):12331-4.
    View in: PubMed
    Score: 0.142
  6. Comparisons between murine polyomavirus and Simian virus 40 show significant differences in small T antigen function. J Virol. 2011 Oct; 85(20):10649-58.
    View in: PubMed
    Score: 0.109
  7. Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell. 1990 Jan 12; 60(1):167-76.
    View in: PubMed
    Score: 0.098
  8. Regulation of pp60c-src and its interaction with polyomavirus middle T antigen in insect cells. J Virol. 1990 Jan; 64(1):61-8.
    View in: PubMed
    Score: 0.097
  9. Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: separation of focus formation and soft-agar growth in transformation assays and correlations with kinase activities in vitro. J Virol. 1988 Sep; 62(9):3407-14.
    View in: PubMed
    Score: 0.089
  10. The p110alpha isoform of phosphatidylinositol 3-kinase is essential for polyomavirus middle T antigen-mediated transformation. J Virol. 2007 Jul; 81(13):7069-76.
    View in: PubMed
    Score: 0.081
  11. The p110a and p110ß isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis. Genes Dev. 2012 Jul 15; 26(14):1573-86.
    View in: PubMed
    Score: 0.029
  12. Transformation-defective mutants of polyomavirus middle T antigen associate with phosphatidylinositol 3-kinase (PI 3-kinase) but are unable to maintain wild-type levels of PI 3-kinase products in intact cells. J Virol. 1992 Mar; 66(3):1702-8.
    View in: PubMed
    Score: 0.028
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.