Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Harvey Cantor


2002 - –
2005 - –
Fellow in Medical Sciences
2010 - –


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI048125 (CANTOR, HARVEY) Apr 1, 2000 - Nov 30, 2021
    Regulation of the follicular T-cell response to autoimmunity
    Role: Principal Investigator
  2. T32CA070083 (CANTOR, HARVEY) May 5, 1997 - Feb 28, 2015
    Postdoctoral Training Program in Cancer Immunology
    Role: Principal Investigator
  3. R01AI037562 (CANTOR, HARVEY) Jul 1, 1996 - Jan 31, 2022
    Immunologic mechanisms that prevent autoimmunity
    Role: Principal Investigator
  4. P01AI037833 (CANTOR, HARVEY) Jun 1, 1995 - May 31, 1999
    Role: Co-Principal Investigator
  5. R01AI036105 (CANTOR, HARVEY) May 1, 1994 - Apr 30, 1998
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wight AE, Sido JM, Degryse S, Ao L, Nakagawa H, Qiu Vivian Y, Shen X, Oseghali O, Kim HJ, Cantor H. Antibody-mediated blockade of the IL23 receptor destabilizes intratumoral regulatory T cells and enhances immunotherapy. Proc Natl Acad Sci U S A. 2022 05 03; 119(18):e2200757119. PMID: 35482921; PMCID: PMC9170135.
    Citations:    Fields:    Translation:HumansCells
  2. Shen X, Qiu Y, Wight AE, Kim HJ, Cantor H. Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain. Proc Natl Acad Sci U S A. 2022 02 22; 119(8). PMID: 35177477; PMCID: PMC8872761.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Kim HJ, Cantor H. From antibody specificity to T cell recognition. J Exp Med. 2021 04 05; 218(4). PMID: 33710256.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Cantor H, Kim HJ. A new chapter in the CD8 T reg story. J Exp Med. 2021 01 04; 218(1). PMID: 33180093.
    Citations: 1     Fields:    Translation:Cells
  5. Choi IK, Wang Z, Ke Q, Hong M, Paul DW, Fernandes SM, Hu Z, Stevens J, Guleria I, Kim HJ, Cantor H, Wucherpfennig KW, Brown JR, Ritz J, Zhang B. Mechanism of EBV inducing anti-tumour immunity and its therapeutic use. Nature. 2021 02; 590(7844):157-162. PMID: 33361812.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  6. Kim HJ, Cantor H, Cosmopoulos K. Overcoming Immune Checkpoint Blockade Resistance via EZH2 Inhibition. Trends Immunol. 2020 10; 41(10):948-963. PMID: 32976740.
    Citations: 14     Fields:    Translation:Humans
  7. Shen E, Rabe H, Luo L, Wang L, Wang Q, Yin J, Yang X, Liu W, Sido JM, Nakagawa H, Ao L, Kim HJ, Cantor H, Leavenworth JW. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor. Cell Rep. 2020 Apr 28; 31(4):107575. PMID: 32348761.
    Citations: 2     Fields:    
  8. Choi JY, Eskandari SK, Cai S, Sulkaj I, Assaker JP, Allos H, AlHaddad J, Muhsin SA, Alhussain E, Mansouri A, Yeung MY, Seelen MAJ, Kim HJ, Cantor H, Azzi JR. Regulatory CD8 T cells that recognize Qa-1 expressed by CD4 T-helper cells inhibit rejection of heart allografts. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):6042-6046. PMID: 32111690; PMCID: PMC7084119.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  9. Lang PA, Crome SQ, Xu HC, Lang KS, Chapatte L, Deenick EK, Grusdat M, Pandyra AA, Pozdeev VI, Wang R, Holderried TAW, Cantor H, Diefenbach A, Elford AR, McIlwain DR, Recher M, Häussinger D, Mak TW, Ohashi PS. NK Cells Regulate CD8+ T Cell Mediated Autoimmunity. Front Cell Infect Microbiol. 2020; 10:36. PMID: 32117809; PMCID: PMC7031256.
    Citations: 6     Fields:    Translation:AnimalsCells
  10. Shen E, Rabe H, Luo L, Wang L, Wang Q, Yin J, Yang X, Liu W, Sido JM, Nakagawa H, Ao L, Kim HJ, Cantor H, Leavenworth JW. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor. Cell Rep. 2019 11 12; 29(7):1848-1861.e6. PMID: 31722202.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  11. Kim HJ, Cantor H. Regulatory T cells subdue an autoimmune disease. Nature. 2019 08; 572(7770):443-445. PMID: 31427795.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Nakagawa H, Wang L, Cantor H, Kim HJ. New Insights Into the Biology of CD8 Regulatory T Cells. Adv Immunol. 2018; 140:1-20. PMID: 30366517.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  13. Shen E, Wang Q, Rabe H, Liu W, Cantor H, Leavenworth JW. Chromatin remodeling by the NuRD complex regulates development of follicular helper and regulatory T cells. Proc Natl Acad Sci U S A. 2018 06 26; 115(26):6780-6785. PMID: 29891681.
    Citations: 10     Fields:    Translation:AnimalsCells
  14. Yates K, Bi K, Haining WN, Cantor H, Kim HJ. Comparative transcriptome analysis reveals distinct genetic modules associated with Helios expression in intratumoral regulatory T cells. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):2162-2167. PMID: 29440380; PMCID: PMC5834721.
    Citations: 21     Fields:    Translation:AnimalsCells
  15. Choi IK, Wang Z, Ke Q, Hong M, Qian Y, Zhao X, Liu Y, Kim HJ, Ritz J, Cantor H, Rajewsky K, Wucherpfennig KW, Zhang B. Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4+ and CD8+ T cell responses. Proc Natl Acad Sci U S A. 2018 01 23; 115(4):E686-E695. PMID: 29311309; PMCID: PMC5789919.
    Citations: 14     Fields:    Translation:AnimalsCells
  16. Albertsson AM, Zhang X, Vontell R, Bi D, Bronson RT, Supramaniam V, Baburamani AA, Hua S, Nazmi A, Cardell S, Zhu C, Cantor H, Mallard C, Hagberg H, Leavenworth JW, Wang X. ?d T Cells Contribute to Injury in the Developing Brain. Am J Pathol. 2018 03; 188(3):757-767. PMID: 29248460; PMCID: PMC5840494.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  17. Xu HC, Huang J, Pandyra AA, Lang E, Zhuang Y, Thöns C, Timm J, Häussinger D, Colonna M, Cantor H, Lang KS, Lang PA. Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral Infection. Cell Rep. 2017 Nov 28; 21(9):2528-2540. PMID: 29186689.
    Citations: 15     Fields:    Translation:AnimalsCells
  18. Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW. Erratum: The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection. Nat Immunol. 2017 09 19; 18(10):1173. PMID: 28926530.
    Citations: 1     Fields:    
  19. Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW. The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection. Nat Immunol. 2017 Jul; 18(7):791-799. PMID: 28530712; PMCID: PMC5753758.
    Citations: 29     Fields:    Translation:AnimalsCells
  20. Bian Y, Shang S, Siddiqui S, Zhao J, Joosten SA, Ottenhoff THM, Cantor H, Wang CR. MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8+ T cells and contributes to protection against infection. PLoS Pathog. 2017 May; 13(5):e1006384. PMID: 28475642; PMCID: PMC5435364.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  21. Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, Wang J, Ke Y, Hu H, Cao X, Wang D, Cantor H, Gao X, Lu L. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med. 2017 05 01; 214(5):1453-1469. PMID: 28400474; PMCID: PMC5413330.
    Citations: 23     Fields:    Translation:AnimalsCells
  22. Nakagawa H, Sido JM, Reyes EE, Kiers V, Cantor H, Kim HJ. Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity. Proc Natl Acad Sci U S A. 2016 May 31; 113(22):6248-53. PMID: 27185917; PMCID: PMC4896716.
    Citations: 67     Fields:    Translation:AnimalsCells
  23. Yin J, Leavenworth JW, Li Y, Luo Q, Xie H, Liu X, Huang S, Yan H, Fu Z, Zhang LY, Zhang L, Hao J, Wu X, Deng X, Roberts CW, Orkin SH, Cantor H, Wang X. Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity. Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52):15988-93. PMID: 26668377; PMCID: PMC4702963.
    Citations: 67     Fields:    Translation:HumansAnimalsCells
  24. Kim HJ, Barnitz RA, Kreslavsky T, Brown FD, Moffett H, Lemieux ME, Kaygusuz Y, Meissner T, Holderried TA, Chan S, Kastner P, Haining WN, Cantor H. Stable inhibitory activity of regulatory T cells requires the transcription factor Helios. Science. 2015 Oct 16; 350(6258):334-9. PMID: 26472910; PMCID: PMC4627635.
    Citations: 165     Fields:    Translation:AnimalsCells
  25. Leavenworth JW, Verbinnen B, Wang Q, Shen E, Cantor H. Intracellular osteopontin regulates homeostasis and function of natural killer cells. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):494-9. PMID: 25550515; PMCID: PMC4299239.
    Citations: 19     Fields:    Translation:AnimalsCells
  26. Leavenworth JW, Verbinnen B, Yin J, Huang H, Cantor H. A p85a-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells. Nat Immunol. 2015 Jan; 16(1):96-106. PMID: 25436971; PMCID: PMC4405167.
    Citations: 66     Fields:    Translation:AnimalsCells
  27. Kim HJ, Cantor H. The path to reactivation of antitumor immunity and checkpoint immunotherapy. Cancer Immunol Res. 2014 Oct; 2(10):926-36. PMID: 25281320.
    Citations: 16     Fields:    Translation:HumansCells
  28. Kim HJ, Cantor H. CD4 T-cell subsets and tumor immunity: the helpful and the not-so-helpful. Cancer Immunol Res. 2014 Feb; 2(2):91-8. PMID: 24778273.
    Citations: 151     Fields:    Translation:HumansCells
  29. Zhou P, Shaffer DR, Alvarez Arias DA, Nakazaki Y, Pos W, Torres AJ, Cremasco V, Dougan SK, Cowley GS, Elpek K, Brogdon J, Lamb J, Turley SJ, Ploegh HL, Root DE, Love JC, Dranoff G, Hacohen N, Cantor H, Wucherpfennig KW. In vivo discovery of immunotherapy targets in the tumour microenvironment. Nature. 2014 Feb 06; 506(7486):52-7. PMID: 24476824.
    Citations: 99     Fields:    Translation:AnimalsCells
  30. Alvarez Arias DA, Kim HJ, Zhou P, Holderried TA, Wang X, Dranoff G, Cantor H. Disruption of CD8+ Treg activity results in expansion of T follicular helper cells and enhanced antitumor immunity. Cancer Immunol Res. 2014 Mar; 2(3):207-16. PMID: 24778317.
    Citations: 21     Fields:    Translation:AnimalsCells
  31. Holderried TA, Lang PA, Kim HJ, Cantor H. Genetic disruption of CD8+ Treg activity enhances the immune response to viral infection. Proc Natl Acad Sci U S A. 2013 Dec 24; 110(52):21089-94. PMID: 24324159.
    Citations: 27     Fields:    Translation:AnimalsCells
  32. Kreslavsky T, Kim HJ, Koralov SB, Ghitza D, Buch T, Cantor H, Rajewsky K, von Boehmer H. Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes. J Exp Med. 2013 Sep 23; 210(10):1911-8. PMID: 23980099.
    Citations: 7     Fields:    Translation:AnimalsCells
  33. Leavenworth JW, Tang X, Kim HJ, Wang X, Cantor H. Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells. J Clin Invest. 2013 Mar; 123(3):1382-9. PMID: 23376792; PMCID: PMC3582146.
    Citations: 39     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  34. Yao Y, Han W, Liang J, Ji J, Wang J, Cantor H, Lu L. Glatiramer acetate ameliorates inflammatory bowel disease in mice through the induction of Qa-1-restricted CD8? regulatory cells. Eur J Immunol. 2013 Jan; 43(1):125-36. PMID: 23002042.
    Citations: 10     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  35. Kim HJ, Cantor H. Regulation of self-tolerance by Qa-1-restricted CD8(+) regulatory T cells. Semin Immunol. 2011 Dec; 23(6):446-52. PMID: 22136694.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  36. Wang X, Werneck MB, Wilson BG, Kim HJ, Kluk MJ, Thom CS, Wischhusen JW, Evans JA, Jesneck JL, Nguyen P, Sansam CG, Cantor H, Roberts CW. TCR-dependent transformation of mature memory phenotype T cells in mice. J Clin Invest. 2011 Oct; 121(10):3834-45. PMID: 21926465; PMCID: PMC3195451.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  37. Leavenworth JW, Wang X, Wenander CS, Spee P, Cantor H. Mobilization of natural killer cells inhibits development of collagen-induced arthritis. Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35):14584-9. PMID: 21873193.
    Citations: 37     Fields:    Translation:AnimalsCells
  38. Varthaman A, Clement M, Khallou-Laschet J, Fornasa G, Gaston AT, Dussiot M, Caligiuri G, Cantor H, Kaveri S, Nicoletti A. Physiological induction of regulatory Qa-1-restricted CD8+ T cells triggered by endogenous CD4+ T cell responses. PLoS One. 2011; 6(6):e21628. PMID: 21738737.
    Citations: 8     Fields:    Translation:AnimalsCells
  39. Kim HJ, Wang X, Radfar S, Sproule TJ, Roopenian DC, Cantor H. CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):2010-5. PMID: 21233417.
    Citations: 84     Fields:    Translation:AnimalsCells
  40. Kim HJ, Verbinnen B, Tang X, Lu L, Cantor H. Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance. Nature. 2010 Sep 16; 467(7313):328-32. PMID: 20844537.
    Citations: 161     Fields:    Translation:AnimalsCells
  41. Mitsdoerffer M, Lee Y, Jäger A, Kim HJ, Korn T, Kolls JK, Cantor H, Bettelli E, Kuchroo VK. Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14292-7. PMID: 20660725.
    Citations: 244     Fields:    Translation:AnimalsCells
  42. Varthaman A, Khallou-Laschet J, Clement M, Fornasa G, Kim HJ, Gaston AT, Dussiot M, Caligiuri G, Herbelin A, Kaveri S, Cantor H, Nicoletti A. Control of T cell reactivation by regulatory Qa-1-restricted CD8+ T cells. J Immunol. 2010 Jun 15; 184(12):6585-91. PMID: 20488793.
    Citations: 16     Fields:    Translation:AnimalsCellsPHPublic Health
  43. Alvarez Arias DA, McCarty N, Lu L, Maldonado RA, Shinohara ML, Cantor H. Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2556-61. PMID: 20133794.
    Citations: 3     Fields:    Translation:AnimalsCells
  44. Leavenworth JW, Schellack C, Kim HJ, Lu L, Spee P, Cantor H. Analysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab')2. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2562-7. PMID: 20133787.
    Citations: 32     Fields:    Translation:AnimalsCells
  45. Egli D, Sandler VM, Shinohara ML, Cantor H, Eggan K. Reprogramming after chromosome transfer into mouse blastomeres. Curr Biol. 2009 Aug 25; 19(16):1403-9. PMID: 19682906.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  46. Cantor H, Shinohara ML. Regulation of T-helper-cell lineage development by osteopontin: the inside story. Nat Rev Immunol. 2009 02; 9(2):137-41. PMID: 19096390.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  47. Cornejo MG, Kharas MG, Werneck MB, Le Bras S, Moore SA, Ball B, Beylot-Barry M, Rodig SJ, Aster JC, Lee BH, Cantor H, Merlio JP, Gilliland DG, Mercher T. Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models. Blood. 2009 Mar 19; 113(12):2746-54. PMID: 19139084; PMCID: PMC2661862.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  48. Lu L, Kim HJ, Werneck MB, Cantor H. Regulation of CD8+ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease. Proc Natl Acad Sci U S A. 2008 Dec 09; 105(49):19420-5. PMID: 19047627.
    Citations: 56     Fields:    Translation:AnimalsCells
  49. Lu L, Cantor H. Generation and regulation of CD8(+) regulatory T cells. Cell Mol Immunol. 2008 Dec; 5(6):401-6. PMID: 19118505.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  50. Shinohara ML, Kim JH, Garcia VA, Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity. 2008 Jul 18; 29(1):68-78. PMID: 18619869.
    Citations: 104     Fields:    Translation:AnimalsCells
  51. Werneck MB, Lugo-Villarino G, Hwang ES, Cantor H, Glimcher LH. T-bet plays a key role in NK-mediated control of melanoma metastatic disease. J Immunol. 2008 Jun 15; 180(12):8004-10. PMID: 18523263; PMCID: PMC3709580.
    Citations: 47     Fields:    Translation:AnimalsCells
  52. Shinohara ML, Kim HJ, Kim JH, Garcia VA, Cantor H. Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. Proc Natl Acad Sci U S A. 2008 May 20; 105(20):7235-9. PMID: 18480255.
    Citations: 71     Fields:    Translation:HumansCells
  53. Zhou J, Matsuoka M, Cantor H, Homer R, Enelow RI. Cutting edge: engagement of NKG2A on CD8+ effector T cells limits immunopathology in influenza pneumonia. J Immunol. 2008 Jan 01; 180(1):25-9. PMID: 18096998.
    Citations: 32     Fields:    Translation:AnimalsCells
  54. Colmenero P, Zhang AL, Qian T, Lu L, Cantor H, Söderström K, Engleman EG. Qa-1(b)-dependent modulation of dendritic cell and NK cell cross-talk in vivo. J Immunol. 2007 Oct 01; 179(7):4608-15. PMID: 17878358.
    Citations: 6     Fields:    Translation:AnimalsCells
  55. Lu L, Ikizawa K, Hu D, Werneck MB, Wucherpfennig KW, Cantor H. Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway. Immunity. 2007 May; 26(5):593-604. PMID: 17509909; PMCID: PMC3428267.
    Citations: 107     Fields:    Translation:AnimalsCells
  56. Shinohara ML, Cantor H. The bridge between dendritic cells and asthma. Nat Med. 2007 May; 13(5):536-8. PMID: 17479095.
    Citations: 5     Fields:    Translation:HumansCells
  57. Lu L, Werneck MB, Cantor H. The immunoregulatory effects of Qa-1. Immunol Rev. 2006 Aug; 212:51-9. PMID: 16903905.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  58. Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H. Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol. 2006 May; 7(5):498-506. PMID: 16604075.
    Citations: 149     Fields:    Translation:HumansAnimalsCells
  59. Shinohara ML, Jansson M, Hwang ES, Werneck MB, Glimcher LH, Cantor H. T-bet-dependent expression of osteopontin contributes to T cell polarization. Proc Natl Acad Sci U S A. 2005 Nov 22; 102(47):17101-6. PMID: 16286640; PMCID: PMC1288014.
    Citations: 69     Fields:    Translation:AnimalsCells
  60. Paust S, Cantor H. Regulatory T cells and autoimmune disease. Immunol Rev. 2005 Apr; 204:195-207. PMID: 15790360.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  61. Bach JF, Bendelac A, Brenner MB, Cantor H, De Libero G, Kronenberg M, Lanier LL, Raulet DH, Shlomchik MJ, von Herrath MG. The role of innate immunity in autoimmunity. J Exp Med. 2004 Dec 20; 200(12):1527-31. PMID: 15611284; PMCID: PMC2211986.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  62. McCarty N, Paust S, Ikizawa K, Dan I, Li X, Cantor H. Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes. Nat Immunol. 2005 Jan; 6(1):65-72. PMID: 15608642.
    Citations: 20     Fields:    Translation:AnimalsCells
  63. Sarantopoulos S, Lu L, Cantor H. Qa-1 restriction of CD8+ suppressor T cells. J Clin Invest. 2004 Nov; 114(9):1218-21. PMID: 15520850; PMCID: PMC524234.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  64. Jacobs JP, Pettit AR, Shinohara ML, Jansson M, Cantor H, Gravallese EM, Mathis D, Benoist C. Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis. Arthritis Rheum. 2004 Aug; 50(8):2685-94. PMID: 15334485.
    Citations: 10     Fields:    Translation:AnimalsCells
  65. Paust S, Lu L, McCarty N, Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci U S A. 2004 Jul 13; 101(28):10398-403. PMID: 15235129; PMCID: PMC478583.
    Citations: 103     Fields:    Translation:AnimalsCells
  66. McCarty N, Shinohara ML, Lu L, Cantor H. Detailed analysis of gene expression during development of T cell lineages in the thymus. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9339-44. PMID: 15190182; PMCID: PMC438978.
    Citations: 3     Fields:    Translation:AnimalsCells
  67. Hu D, Ikizawa K, Lu L, Sanchirico ME, Shinohara ML, Cantor H. Analysis of regulatory CD8 T cells in Qa-1-deficient mice. Nat Immunol. 2004 May; 5(5):516-23. PMID: 15098030.
    Citations: 130     Fields:    Translation:AnimalsCells
  68. Panoutsakopoulou V, Huster KM, McCarty N, Feinberg E, Wang R, Wucherpfennig KW, Cantor H. Suppression of autoimmune disease after vaccination with autoreactive T cells that express Qa-1 peptide complexes. J Clin Invest. 2004 Apr; 113(8):1218-24. PMID: 15085201; PMCID: PMC385407.
    Citations: 25     Fields:    Translation:AnimalsCellsPHPublic Health
  69. Cantor H. Reviving suppression? Nat Immunol. 2004 Apr; 5(4):347-9. PMID: 15052259.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  70. Kissler S, Lu L, Cantor H. Thymic selection can compensate for mutations affecting T cell activation and generate a normal T cell repertoire in mutant mice. Proc Natl Acad Sci U S A. 2004 Jan 06; 101(1):210-4. PMID: 14694195; PMCID: PMC314164.
    Citations:    Fields:    Translation:AnimalsCells
  71. Weber GF, Zawaideh S, Hikita S, Kumar VA, Cantor H, Ashkar S. Phosphorylation-dependent interaction of osteopontin with its receptors regulates macrophage migration and activation. J Leukoc Biol. 2002 Oct; 72(4):752-61. PMID: 12377945.
    Citations: 92     Fields:    Translation:AnimalsCells
  72. Yang XF, Ye Q, Press B, Han RZ, Bassing CH, Sleckman BP, Alt FW, Cantor H. Analysis of the complex genomic structure of Bcl-x and its relationship to Bcl-x(gamma) expression after CD28-dependent costimulation. Mol Immunol. 2002 Sep; 39(1-2):45-55. PMID: 12213327.
    Citations: 6     Fields:    Translation:AnimalsCells
  73. Ye Q, Press B, Kissler S, Yang XF, Lu L, Bassing CH, Sleckman BP, Jansson M, Panoutsakopoulou V, Trimble LA, Alt FW, Cantor H. T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice. J Exp Med. 2002 Jul 01; 196(1):87-95. PMID: 12093873; PMCID: PMC2194014.
    Citations: 6     Fields:    Translation:AnimalsCells
  74. Trimble LA, Prince KA, Pestano GA, Daley J, Cantor H. Fas-dependent elimination of nonselected CD8 cells and lpr disease. J Immunol. 2002 May 15; 168(10):4960-7. PMID: 11994447.
    Citations: 3     Fields:    Translation:AnimalsCells
  75. Huster KM, Panoutsakopoulou V, Prince K, Sanchirico ME, Cantor H. T cell-dependent and -independent pathways to tissue destruction following herpes simplex virus-1 infection. Eur J Immunol. 2002 05; 32(5):1414-9. PMID: 11981829.
    Citations: 8     Fields:    Translation:AnimalsCells
  76. Weber GF, Bronson RT, Ilagan J, Cantor H, Schmits R, Mak TW. Absence of the CD44 gene prevents sarcoma metastasis. Cancer Res. 2002 Apr 15; 62(8):2281-6. PMID: 11956084.
    Citations: 43     Fields:    Translation:Animals
  77. Jansson M, Panoutsakopoulou V, Baker J, Klein L, Cantor H. Cutting edge: Attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin-deficient mice. J Immunol. 2002 Mar 01; 168(5):2096-9. PMID: 11859094.
    Citations: 60     Fields:    Translation:AnimalsCells
  78. Weber GF, Cantor H. Differential roles of osteopontin/Eta-1 in early and late lpr disease. Clin Exp Immunol. 2001 Dec; 126(3):578-83. PMID: 11737079; PMCID: PMC1906233.
    Citations: 13     Fields:    Translation:AnimalsCells
  79. Nguyen QD, Uy HS, Merchant A, Medina CA, Baltatzis S, Zhao T, Zhao ZS, Cantor H, Foster CS. Effect of Fas and Fas ligand deficiency in resistance of C57BL/6 mice to HSV-1 keratitis and chorioretinitis. Invest Ophthalmol Vis Sci. 2001 Oct; 42(11):2505-9. PMID: 11581190.
    Citations: 2     Fields:    Translation:AnimalsCells
  80. Panoutsakopoulou V, Sanchirico ME, Huster KM, Jansson M, Granucci F, Shim DJ, Wucherpfennig KW, Cantor H. Analysis of the relationship between viral infection and autoimmune disease. Immunity. 2001 Jul; 15(1):137-47. PMID: 11485745.
    Citations: 34     Fields:    Translation:AnimalsCells
  81. Adler B, Ashkar S, Cantor H, Weber GF. Costimulation by extracellular matrix proteins determines the response to TCR ligation. Cell Immunol. 2001 May 25; 210(1):30-40. PMID: 11485350.
    Citations: 9     Fields:    Translation:AnimalsCells
  82. Panoutsakopoulou V, Cantor H. On the relationship between viral infection and autoimmunity. J Autoimmun. 2001 May; 16(3):341-5. PMID: 11334502.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  83. Suri-Payer E, Cantor H. Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J Autoimmun. 2001 Mar; 16(2):115-23. PMID: 11247637.
    Citations: 64     Fields:    Translation:AnimalsCells
  84. Wang R, Ramaswamy S, Hu D, Cantor H. Definition of a novel binding site on CD8 cells for a conserved region of the MHC class Ib molecule Qa-1 that regulates IFN-gamma expression. Eur J Immunol. 2001 Jan; 31(1):87-93. PMID: 11169442.
    Citations: 5     Fields:    Translation:AnimalsCells
  85. Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Jansson M, Zawaideh S, Rittling SR, Denhardt DT, Glimcher MJ, Cantor H. Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science. 2000 Feb 04; 287(5454):860-4. PMID: 10657301.
    Citations: 325     Fields:    Translation:AnimalsCells
  86. Cantor H. T-cell receptor crossreactivity and autoimmune disease. Adv Immunol. 2000; 75:209-33. PMID: 10879285.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  87. Pestano GA, Zhou Y, Trimble LA, Daley J, Weber GF, Cantor H. Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death. Science. 1999 May 14; 284(5417):1187-91. PMID: 10325233.
    Citations: 20     Fields:    Translation:AnimalsCells
  88. Adler B, Weber GF, Cantor H. Activation of T cells by superantigen: cytokine production but not apoptosis depends on MEK-1 activity. Eur J Immunol. 1998 11; 28(11):3749-54. PMID: 9842917.
    Citations: 4     Fields:    Translation:AnimalsCells
  89. Zhao ZS, Granucci F, Yeh L, Schaffer PA, Cantor H. Molecular mimicry by herpes simplex virus-type 1: autoimmune disease after viral infection. Science. 1998 Feb 27; 279(5355):1344-7. PMID: 9478893.
    Citations: 133     Fields:    Translation:AnimalsCells
  90. Noble A, Pestano GA, Cantor H. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. J Immunol. 1998 Jan 15; 160(2):559-65. PMID: 9551888.
    Citations: 16     Fields:    Translation:AnimalsCells
  91. Noble A, Zhao ZS, Cantor H. Suppression of immune responses by CD8 cells. II. Qa-1 on activated B cells stimulates CD8 cell suppression of T helper 2 responses. J Immunol. 1998 Jan 15; 160(2):566-71. PMID: 9551889.
    Citations: 36     Fields:    Translation:AnimalsCells
  92. Yang XF, Weber GF, Cantor H. A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells. Immunity. 1997 Nov; 7(5):629-39. PMID: 9390687; PMCID: PMC3908546.
    Citations: 34     Fields:    Translation:AnimalsCells
  93. Weber GF, Mirza NM, Yunis EJ, Dubey D, Cantor H. Localization and treatment of an oxidation-sensitive defect within the TCR-coupled signalling pathway that is associated with normal and premature immunologic aging. Growth Dev Aging. 1997 Fall-Winter; 61(3-4):191-207. PMID: 9546110.
    Citations:    Fields:    Translation:AnimalsCells
  94. Weber GF, Daley J, Kraeft SK, Chen LB, Cantor H. Measurement of apoptosis in heterogenous cell populations. Cytometry. 1997 Feb 01; 27(2):136-44. PMID: 9012380.
    Citations: 2     Fields:    Translation:AnimalsCells
  95. Weber GF, Ashkar S, Cantor H. Interaction between CD44 and osteopontin as a potential basis for metastasis formation. Proc Assoc Am Physicians. 1997 Jan; 109(1):1-9. PMID: 9010911.
    Citations: 33     Fields:    Translation:HumansAnimals
  96. Weber GF, Cantor H. The immunology of Eta-1/osteopontin. Cytokine Growth Factor Rev. 1996 Oct; 7(3):241-8. PMID: 8971479.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  97. Weber GF, Ashkar S, Glimcher MJ, Cantor H. Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science. 1996 Jan 26; 271(5248):509-12. PMID: 8560266.
    Citations: 245     Fields:    Translation:AnimalsCells
  98. Avery AC, Zhao ZS, Rodriguez A, Bikoff EK, Soheilian M, Foster CS, Cantor H. Resistance to herpes stromal keratitis conferred by an IgG2a-derived peptide. Nature. 1995 Aug 03; 376(6539):431-4. PMID: 7630419.
    Citations: 18     Fields:    Translation:AnimalsCells
  99. Cantor H. The role of Eta-1/osteopontin in the pathogenesis of immunological disorders. Ann N Y Acad Sci. 1995 Apr 21; 760:143-50. PMID: 7785892.
    Citations: 9     Fields:    Translation:AnimalsCells
  100. Weber GF, Abromson-Leeman S, Cantor H. A signaling pathway coupled to T cell receptor ligation by MMTV superantigen leading to transient activation and programmed cell death. Immunity. 1995 Apr; 2(4):363-72. PMID: 7719939.
    Citations: 8     Fields:    Translation:AnimalsCells
  101. Avery AC, Markowitz JS, Grusby MJ, Glimcher LH, Cantor H. Activation of T cells by superantigen in class II-negative mice. J Immunol. 1994 Dec 01; 153(11):4853-61. PMID: 7963549.
    Citations: 12     Fields:    Translation:AnimalsCells
  102. Weber GF, Cantor H. Phosphatidylinositol synthesis is a proximal event in intracellular signaling coupled to T cell receptor ligation. Differential induction by conventional antigen and retroviral superantigen. J Immunol. 1994 May 01; 152(9):4433-43. PMID: 7908918.
    Citations: 3     Fields:    Translation:AnimalsCells
  103. Crump AL, Grusby MJ, Glimcher LH, Cantor H. Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10739-43. PMID: 7902569; PMCID: PMC47853.
    Citations: 15     Fields:    Translation:AnimalsCells
  104. Weber GF, Cantor H. HIV glycoprotein as a superantigen. A mechanism of autoimmunity and implications for a vaccination strategy. Med Hypotheses. 1993 Sep; 41(3):247-50. PMID: 8259084.
    Citations: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  105. Patarca R, Fletcher MA, Cantor H. Structural features of two T-cell-specific genes that suggest a potential role in HTLV-I-associated pathology. AIDS Res Hum Retroviruses. 1993 Feb; 9(2):105-7. PMID: 8096144.
    Citations:    Fields:    Translation:HumansAnimalsCells
  106. Cantor H, Crump AL, Raman VK, Liu H, Markowitz JS, Grusby MJ, Glimcher LH. Immunoregulatory effects of superantigens: interactions of staphyloc