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Cantor, Harvey
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Harvey Cantor
Title
Baruj Benacerraf Professor of Immunology
Institution
Dana-Farber Cancer Institute
Department
Immunology
Address
Dana-Farber Cancer Institute
Cancer Immunology & Virology, Smith 722
450 Brookline Ave
Boston MA 02215
Phone
617/632-3348
Fax
617/632-4630
vCard
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awards and honors
|
webpage
|
research activities and funding
|
selected publications
|
Biography
awards and honors
2002 - –
Member
2005 - –
Fellow in Medical Sciences
2010 - –
Member
Overview
webpage
Departmental website
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
R01AI048125
(CANTOR, HARVEY)
Apr 1, 2000 - Nov 30, 2021
NIH
Regulation of the follicular T-cell response to autoimmunity
Role: Principal Investigator
T32CA070083
(CANTOR, HARVEY)
May 5, 1997 - Feb 28, 2015
NIH
Postdoctoral Training Program in Cancer Immunology
Role: Principal Investigator
R01AI037562
(CANTOR, HARVEY)
Jul 1, 1996 - Jan 31, 2022
NIH
Immunologic mechanisms that prevent autoimmunity
Role: Principal Investigator
P01AI037833
(CANTOR, HARVEY)
Jun 1, 1995 - May 31, 1999
NIH
REGULATION OF THE T CELL RESPONSE TO ANTIGEN
Role: Co-Principal Investigator
R01AI036105
(CANTOR, HARVEY)
May 1, 1994 - Apr 30, 1998
NIH
PATHOGENIC MECHANISMS OF MAIDS
Role: Principal Investigator
T32AI007386
(CANTOR, HARVEY)
Aug 1, 1990 - May 31, 2024
NIH
Postdoctoral Training Program in AIDS-related Research
Role: Principal Investigator
U09AI026447
(DOMS, ROBERT W.)
Sep 1, 1987 - Jun 30, 2006
NIH
ACQUIRED IMMUNODEFICIENCY SYNDROME REVIEW
Role: Co-Principal Investigator
R01CA026695
(CANTOR, HARVEY)
May 1, 1980 - Apr 30, 1991
NIH
ANTIGEN-SPECIFIC T-CELL CLONES--GENERATION AND ANALYSIS
Role: Principal Investigator
R37AI012184
(CANTOR, HARVEY)
Jul 1, 1977 - Mar 31, 2008
NIH
T-cell Subpopulations in Transplantation Immunity
Role: Principal Investigator
R01AI012184
(CANTOR, HARVEY)
Jul 1, 1977 - Mar 31, 1997
NIH
T-CELL SUBPOPULATIONS IN TRANSPLANTATION IMMUNITY
Role: Principal Investigator
R01AI013600
(CANTOR, HARVEY)
Jun 1, 1976 - Nov 30, 2004
NIH
IMMUNOBIOLOGY OF LY+ T CELL SUBCLASSES
Role: Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Wight AE, Sido JM, Degryse S, Ao L, Nakagawa H, Qiu Vivian Y,
Shen X
, Oseghali O, Kim HJ,
Cantor H
. Antibody-mediated blockade of the IL23 receptor destabilizes intratumoral regulatory T cells and enhances immunotherapy. Proc Natl Acad Sci U S A. 2022 05 03; 119(18):e2200757119.
PMID:
35482921
; PMCID:
PMC9170135
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Cells
Shen X
,
Qiu Y
, Wight AE, Kim HJ,
Cantor H
. Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain. Proc Natl Acad Sci U S A. 2022 02 22; 119(8).
PMID:
35177477
; PMCID:
PMC8872761
.
Citations:
1
Fields:
Sci
Science
Translation:
Animals
Cells
Kim HJ,
Cantor H
. From antibody specificity to T cell recognition. J Exp Med. 2021 04 05; 218(4).
PMID:
33710256
.
Citations:
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Cantor H
, Kim HJ. A new chapter in the CD8 T reg story. J Exp Med. 2021 01 04; 218(1).
PMID:
33180093
.
Citations:
1
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Cells
Choi IK, Wang Z, Ke Q, Hong M,
Paul DW
, Fernandes SM, Hu Z, Stevens J,
Guleria I
, Kim HJ,
Cantor H
,
Wucherpfennig KW
,
Brown JR
,
Ritz J
,
Zhang B
. Mechanism of EBV inducing anti-tumour immunity and its therapeutic use. Nature. 2021 02; 590(7844):157-162.
PMID:
33361812
.
Citations:
14
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Kim HJ,
Cantor H
, Cosmopoulos K. Overcoming Immune Checkpoint Blockade Resistance via EZH2 Inhibition. Trends Immunol. 2020 10; 41(10):948-963.
PMID:
32976740
.
Citations:
14
Fields:
All
Allergy and Immunology
Translation:
Humans
Shen E, Rabe H, Luo L, Wang L, Wang Q, Yin J, Yang X, Liu W, Sido JM, Nakagawa H, Ao L, Kim HJ,
Cantor H
, Leavenworth JW. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor. Cell Rep. 2020 Apr 28; 31(4):107575.
PMID:
32348761
.
Citations:
2
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Choi JY, Eskandari SK, Cai S, Sulkaj I,
Assaker JP
,
Allos H
, AlHaddad J,
Muhsin SA
, Alhussain E, Mansouri A,
Yeung MY
, Seelen MAJ, Kim HJ,
Cantor H
,
Azzi JR
. Regulatory CD8 T cells that recognize Qa-1 expressed by CD4 T-helper cells inhibit rejection of heart allografts. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):6042-6046.
PMID:
32111690
; PMCID:
PMC7084119
.
Citations:
5
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Lang PA, Crome SQ, Xu HC, Lang KS, Chapatte L, Deenick EK, Grusdat M, Pandyra AA, Pozdeev VI, Wang R, Holderried TAW,
Cantor H
, Diefenbach A, Elford AR, McIlwain DR, Recher M, Häussinger D, Mak TW, Ohashi PS. NK Cells Regulate CD8+ T Cell Mediated Autoimmunity. Front Cell Infect Microbiol. 2020; 10:36.
PMID:
32117809
; PMCID:
PMC7031256
.
Citations:
6
Fields:
Cel
Cell Biology
Com
Communicable Diseases
Mic
Microbiology
Translation:
Animals
Cells
Shen E, Rabe H, Luo L, Wang L, Wang Q, Yin J, Yang X, Liu W, Sido JM, Nakagawa H, Ao L, Kim HJ,
Cantor H
, Leavenworth JW. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor. Cell Rep. 2019 11 12; 29(7):1848-1861.e6.
PMID:
31722202
.
Citations:
16
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Kim HJ,
Cantor H
. Regulatory T cells subdue an autoimmune disease. Nature. 2019 08; 572(7770):443-445.
PMID:
31427795
.
Citations:
1
Fields:
Sci
Science
Translation:
Animals
Cells
Nakagawa H, Wang L,
Cantor H
, Kim HJ. New Insights Into the Biology of CD8 Regulatory T Cells. Adv Immunol. 2018; 140:1-20.
PMID:
30366517
.
Citations:
14
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Shen E, Wang Q, Rabe H, Liu W,
Cantor H
, Leavenworth JW. Chromatin remodeling by the NuRD complex regulates development of follicular helper and regulatory T cells. Proc Natl Acad Sci U S A. 2018 06 26; 115(26):6780-6785.
PMID:
29891681
.
Citations:
10
Fields:
Sci
Science
Translation:
Animals
Cells
Yates K, Bi K, Haining WN,
Cantor H
, Kim HJ. Comparative transcriptome analysis reveals distinct genetic modules associated with Helios expression in intratumoral regulatory T cells. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):2162-2167.
PMID:
29440380
; PMCID:
PMC5834721
.
Citations:
21
Fields:
Sci
Science
Translation:
Animals
Cells
Choi IK, Wang Z, Ke Q, Hong M, Qian Y, Zhao X, Liu Y, Kim HJ,
Ritz J
,
Cantor H
, Rajewsky K,
Wucherpfennig KW
,
Zhang B
. Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4+ and CD8+ T cell responses. Proc Natl Acad Sci U S A. 2018 01 23; 115(4):E686-E695.
PMID:
29311309
; PMCID:
PMC5789919
.
Citations:
14
Fields:
Sci
Science
Translation:
Animals
Cells
Albertsson AM, Zhang X, Vontell R, Bi D,
Bronson RT
, Supramaniam V, Baburamani AA, Hua S, Nazmi A, Cardell S, Zhu C,
Cantor H
, Mallard C, Hagberg H, Leavenworth JW, Wang X. ?d T Cells Contribute to Injury in the Developing Brain. Am J Pathol. 2018 03; 188(3):757-767.
PMID:
29248460
; PMCID:
PMC5840494
.
Citations:
23
Fields:
Pat
Pathology
Translation:
Humans
Animals
Cells
Xu HC, Huang J, Pandyra AA, Lang E,
Zhuang Y
, Thöns C, Timm J, Häussinger D, Colonna M,
Cantor H
, Lang KS, Lang PA. Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral Infection. Cell Rep. 2017 Nov 28; 21(9):2528-2540.
PMID:
29186689
.
Citations:
15
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Animals
Cells
Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J,
Golub TR
,
Cantor H
,
Sharpe AH
,
Novina CD
,
Wucherpfennig KW
. Erratum: The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection. Nat Immunol. 2017 09 19; 18(10):1173.
PMID:
28926530
.
Citations:
1
Fields:
All
Allergy and Immunology
Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J,
Golub TR
,
Cantor H
,
Sharpe AH
,
Novina CD
,
Wucherpfennig KW
. The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection. Nat Immunol. 2017 Jul; 18(7):791-799.
PMID:
28530712
; PMCID:
PMC5753758
.
Citations:
29
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Bian Y, Shang S, Siddiqui S, Zhao J, Joosten SA, Ottenhoff THM,
Cantor H
, Wang CR. MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8+ T cells and contributes to protection against infection. PLoS Pathog. 2017 May; 13(5):e1006384.
PMID:
28475642
; PMCID:
PMC5435364
.
Citations:
22
Fields:
Mic
Microbiology
Translation:
Humans
Animals
Cells
Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, Wang J, Ke Y, Hu H, Cao X, Wang D,
Cantor H
, Gao X, Lu L. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med. 2017 05 01; 214(5):1453-1469.
PMID:
28400474
; PMCID:
PMC5413330
.
Citations:
23
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Animals
Cells
Nakagawa H, Sido JM, Reyes EE, Kiers V,
Cantor H
, Kim HJ. Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity. Proc Natl Acad Sci U S A. 2016 May 31; 113(22):6248-53.
PMID:
27185917
; PMCID:
PMC4896716
.
Citations:
67
Fields:
Sci
Science
Translation:
Animals
Cells
Yin J, Leavenworth JW, Li Y, Luo Q, Xie H, Liu X, Huang S, Yan H, Fu Z, Zhang LY, Zhang L, Hao J, Wu X, Deng X, Roberts CW,
Orkin SH
,
Cantor H
, Wang X. Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity. Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52):15988-93.
PMID:
26668377
; PMCID:
PMC4702963
.
Citations:
67
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Kim HJ, Barnitz RA, Kreslavsky T, Brown FD, Moffett H, Lemieux ME, Kaygusuz Y,
Meissner T
, Holderried TA, Chan S, Kastner P, Haining WN,
Cantor H
. Stable inhibitory activity of regulatory T cells requires the transcription factor Helios. Science. 2015 Oct 16; 350(6258):334-9.
PMID:
26472910
; PMCID:
PMC4627635
.
Citations:
165
Fields:
Sci
Science
Translation:
Animals
Cells
Leavenworth JW, Verbinnen B, Wang Q, Shen E,
Cantor H
. Intracellular osteopontin regulates homeostasis and function of natural killer cells. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):494-9.
PMID:
25550515
; PMCID:
PMC4299239
.
Citations:
19
Fields:
Sci
Science
Translation:
Animals
Cells
Leavenworth JW, Verbinnen B, Yin J, Huang H,
Cantor H
. A p85a-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells. Nat Immunol. 2015 Jan; 16(1):96-106.
PMID:
25436971
; PMCID:
PMC4405167
.
Citations:
66
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Kim HJ,
Cantor H
. The path to reactivation of antitumor immunity and checkpoint immunotherapy. Cancer Immunol Res. 2014 Oct; 2(10):926-36.
PMID:
25281320
.
Citations:
16
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Translation:
Humans
Cells
Kim HJ,
Cantor H
. CD4 T-cell subsets and tumor immunity: the helpful and the not-so-helpful. Cancer Immunol Res. 2014 Feb; 2(2):91-8.
PMID:
24778273
.
Citations:
151
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Translation:
Humans
Cells
Zhou P, Shaffer DR, Alvarez Arias DA, Nakazaki Y, Pos W, Torres AJ, Cremasco V,
Dougan SK
, Cowley GS, Elpek K, Brogdon J, Lamb J, Turley SJ, Ploegh HL, Root DE, Love JC, Dranoff G,
Hacohen N
,
Cantor H
,
Wucherpfennig KW
. In vivo discovery of immunotherapy targets in the tumour microenvironment. Nature. 2014 Feb 06; 506(7486):52-7.
PMID:
24476824
.
Citations:
99
Fields:
Sci
Science
Translation:
Animals
Cells
Alvarez Arias DA, Kim HJ, Zhou P, Holderried TA, Wang X, Dranoff G,
Cantor H
. Disruption of CD8+ Treg activity results in expansion of T follicular helper cells and enhanced antitumor immunity. Cancer Immunol Res. 2014 Mar; 2(3):207-16.
PMID:
24778317
.
Citations:
21
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Translation:
Animals
Cells
Holderried TA, Lang PA, Kim HJ,
Cantor H
. Genetic disruption of CD8+ Treg activity enhances the immune response to viral infection. Proc Natl Acad Sci U S A. 2013 Dec 24; 110(52):21089-94.
PMID:
24324159
.
Citations:
27
Fields:
Sci
Science
Translation:
Animals
Cells
Kreslavsky T, Kim HJ, Koralov SB, Ghitza D, Buch T,
Cantor H
, Rajewsky K, von Boehmer H. Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes. J Exp Med. 2013 Sep 23; 210(10):1911-8.
PMID:
23980099
.
Citations:
7
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Animals
Cells
Leavenworth JW, Tang X, Kim HJ, Wang X,
Cantor H
. Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells. J Clin Invest. 2013 Mar; 123(3):1382-9.
PMID:
23376792
; PMCID:
PMC3582146
.
Citations:
39
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
PH
Public Health
Yao Y, Han W, Liang J, Ji J, Wang J,
Cantor H
, Lu L. Glatiramer acetate ameliorates inflammatory bowel disease in mice through the induction of Qa-1-restricted CD8? regulatory cells. Eur J Immunol. 2013 Jan; 43(1):125-36.
PMID:
23002042
.
Citations:
10
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
PH
Public Health
Kim HJ,
Cantor H
. Regulation of self-tolerance by Qa-1-restricted CD8(+) regulatory T cells. Semin Immunol. 2011 Dec; 23(6):446-52.
PMID:
22136694
.
Citations:
39
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Wang X, Werneck MB, Wilson BG, Kim HJ, Kluk MJ, Thom CS, Wischhusen JW, Evans JA, Jesneck JL, Nguyen P, Sansam CG,
Cantor H
, Roberts CW. TCR-dependent transformation of mature memory phenotype T cells in mice. J Clin Invest. 2011 Oct; 121(10):3834-45.
PMID:
21926465
; PMCID:
PMC3195451
.
Citations:
45
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Leavenworth JW, Wang X, Wenander CS, Spee P,
Cantor H
. Mobilization of natural killer cells inhibits development of collagen-induced arthritis. Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35):14584-9.
PMID:
21873193
.
Citations:
37
Fields:
Sci
Science
Translation:
Animals
Cells
Varthaman A, Clement M, Khallou-Laschet J, Fornasa G, Gaston AT, Dussiot M, Caligiuri G,
Cantor H
, Kaveri S, Nicoletti A. Physiological induction of regulatory Qa-1-restricted CD8+ T cells triggered by endogenous CD4+ T cell responses. PLoS One. 2011; 6(6):e21628.
PMID:
21738737
.
Citations:
8
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
Cells
Kim HJ, Wang X, Radfar S, Sproule TJ, Roopenian DC,
Cantor H
. CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):2010-5.
PMID:
21233417
.
Citations:
84
Fields:
Sci
Science
Translation:
Animals
Cells
Kim HJ, Verbinnen B, Tang X, Lu L,
Cantor H
. Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance. Nature. 2010 Sep 16; 467(7313):328-32.
PMID:
20844537
.
Citations:
161
Fields:
Sci
Science
Translation:
Animals
Cells
Mitsdoerffer M, Lee Y, Jäger A, Kim HJ, Korn T, Kolls JK,
Cantor H
, Bettelli E,
Kuchroo VK
. Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14292-7.
PMID:
20660725
.
Citations:
244
Fields:
Sci
Science
Translation:
Animals
Cells
Varthaman A, Khallou-Laschet J, Clement M, Fornasa G, Kim HJ, Gaston AT, Dussiot M, Caligiuri G, Herbelin A, Kaveri S,
Cantor H
, Nicoletti A. Control of T cell reactivation by regulatory Qa-1-restricted CD8+ T cells. J Immunol. 2010 Jun 15; 184(12):6585-91.
PMID:
20488793
.
Citations:
16
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
PH
Public Health
Alvarez Arias DA, McCarty N, Lu L, Maldonado RA, Shinohara ML,
Cantor H
. Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2556-61.
PMID:
20133794
.
Citations:
3
Fields:
Sci
Science
Translation:
Animals
Cells
Leavenworth JW, Schellack C, Kim HJ, Lu L, Spee P,
Cantor H
. Analysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab')2. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2562-7.
PMID:
20133787
.
Citations:
32
Fields:
Sci
Science
Translation:
Animals
Cells
Egli D, Sandler VM, Shinohara ML,
Cantor H
, Eggan K. Reprogramming after chromosome transfer into mouse blastomeres. Curr Biol. 2009 Aug 25; 19(16):1403-9.
PMID:
19682906
.
Citations:
19
Fields:
Bio
Biology
Translation:
Humans
Animals
Cells
Cantor H
, Shinohara ML. Regulation of T-helper-cell lineage development by osteopontin: the inside story. Nat Rev Immunol. 2009 02; 9(2):137-41.
PMID:
19096390
.
Citations:
54
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Cornejo MG, Kharas MG, Werneck MB, Le Bras S, Moore SA, Ball B, Beylot-Barry M,
Rodig SJ
,
Aster JC
, Lee BH,
Cantor H
, Merlio JP, Gilliland DG, Mercher T. Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models. Blood. 2009 Mar 19; 113(12):2746-54.
PMID:
19139084
; PMCID:
PMC2661862
.
Citations:
31
Fields:
Hem
Hematology
Translation:
Humans
Animals
Cells
Lu L, Kim HJ, Werneck MB,
Cantor H
. Regulation of CD8+ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease. Proc Natl Acad Sci U S A. 2008 Dec 09; 105(49):19420-5.
PMID:
19047627
.
Citations:
56
Fields:
Sci
Science
Translation:
Animals
Cells
Lu L,
Cantor H
. Generation and regulation of CD8(+) regulatory T cells. Cell Mol Immunol. 2008 Dec; 5(6):401-6.
PMID:
19118505
.
Citations:
39
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Shinohara ML,
Kim JH
, Garcia VA,
Cantor H
. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity. 2008 Jul 18; 29(1):68-78.
PMID:
18619869
.
Citations:
104
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Werneck MB, Lugo-Villarino G, Hwang ES,
Cantor H
,
Glimcher LH
. T-bet plays a key role in NK-mediated control of melanoma metastatic disease. J Immunol. 2008 Jun 15; 180(12):8004-10.
PMID:
18523263
; PMCID:
PMC3709580
.
Citations:
47
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Shinohara ML, Kim HJ,
Kim JH
, Garcia VA,
Cantor H
. Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. Proc Natl Acad Sci U S A. 2008 May 20; 105(20):7235-9.
PMID:
18480255
.
Citations:
71
Fields:
Sci
Science
Translation:
Humans
Cells
Zhou J, Matsuoka M,
Cantor H
, Homer R, Enelow RI. Cutting edge: engagement of NKG2A on CD8+ effector T cells limits immunopathology in influenza pneumonia. J Immunol. 2008 Jan 01; 180(1):25-9.
PMID:
18096998
.
Citations:
32
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Colmenero P, Zhang AL, Qian T, Lu L,
Cantor H
, Söderström K, Engleman EG. Qa-1(b)-dependent modulation of dendritic cell and NK cell cross-talk in vivo. J Immunol. 2007 Oct 01; 179(7):4608-15.
PMID:
17878358
.
Citations:
6
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Lu L, Ikizawa K,
Hu D
, Werneck MB,
Wucherpfennig KW
,
Cantor H
. Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway. Immunity. 2007 May; 26(5):593-604.
PMID:
17509909
; PMCID:
PMC3428267
.
Citations:
107
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Shinohara ML,
Cantor H
. The bridge between dendritic cells and asthma. Nat Med. 2007 May; 13(5):536-8.
PMID:
17479095
.
Citations:
5
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Cells
Lu L, Werneck MB,
Cantor H
. The immunoregulatory effects of Qa-1. Immunol Rev. 2006 Aug; 212:51-9.
PMID:
16903905
.
Citations:
30
Fields:
All
Allergy and Immunology
Tra
Transplantation
Translation:
Humans
Animals
Cells
Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS,
Glimcher LH
,
Cantor H
. Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol. 2006 May; 7(5):498-506.
PMID:
16604075
.
Citations:
149
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Shinohara ML, Jansson M, Hwang ES, Werneck MB,
Glimcher LH
,
Cantor H
. T-bet-dependent expression of osteopontin contributes to T cell polarization. Proc Natl Acad Sci U S A. 2005 Nov 22; 102(47):17101-6.
PMID:
16286640
; PMCID:
PMC1288014
.
Citations:
69
Fields:
Sci
Science
Translation:
Animals
Cells
Paust S,
Cantor H
. Regulatory T cells and autoimmune disease. Immunol Rev. 2005 Apr; 204:195-207.
PMID:
15790360
.
Citations:
63
Fields:
All
Allergy and Immunology
Tra
Transplantation
Translation:
Humans
Animals
Cells
Bach JF, Bendelac A,
Brenner MB
,
Cantor H
, De Libero G, Kronenberg M, Lanier LL, Raulet DH, Shlomchik MJ, von Herrath MG. The role of innate immunity in autoimmunity. J Exp Med. 2004 Dec 20; 200(12):1527-31.
PMID:
15611284
; PMCID:
PMC2211986
.
Citations:
16
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
McCarty N, Paust S, Ikizawa K, Dan I, Li X,
Cantor H
. Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes. Nat Immunol. 2005 Jan; 6(1):65-72.
PMID:
15608642
.
Citations:
20
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Sarantopoulos S, Lu L,
Cantor H
. Qa-1 restriction of CD8+ suppressor T cells. J Clin Invest. 2004 Nov; 114(9):1218-21.
PMID:
15520850
; PMCID:
PMC524234
.
Citations:
54
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Jacobs JP, Pettit AR, Shinohara ML, Jansson M,
Cantor H
,
Gravallese EM
,
Mathis D
, Benoist C. Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis. Arthritis Rheum. 2004 Aug; 50(8):2685-94.
PMID:
15334485
.
Citations:
10
Fields:
Rhe
Rheumatology
Translation:
Animals
Cells
Paust S, Lu L, McCarty N,
Cantor H
. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci U S A. 2004 Jul 13; 101(28):10398-403.
PMID:
15235129
; PMCID:
PMC478583
.
Citations:
103
Fields:
Sci
Science
Translation:
Animals
Cells
McCarty N, Shinohara ML, Lu L,
Cantor H
. Detailed analysis of gene expression during development of T cell lineages in the thymus. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9339-44.
PMID:
15190182
; PMCID:
PMC438978
.
Citations:
3
Fields:
Sci
Science
Translation:
Animals
Cells
Hu D
, Ikizawa K, Lu L, Sanchirico ME, Shinohara ML,
Cantor H
. Analysis of regulatory CD8 T cells in Qa-1-deficient mice. Nat Immunol. 2004 May; 5(5):516-23.
PMID:
15098030
.
Citations:
130
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Panoutsakopoulou V, Huster KM, McCarty N, Feinberg E, Wang R,
Wucherpfennig KW
,
Cantor H
. Suppression of autoimmune disease after vaccination with autoreactive T cells that express Qa-1 peptide complexes. J Clin Invest. 2004 Apr; 113(8):1218-24.
PMID:
15085201
; PMCID:
PMC385407
.
Citations:
25
Fields:
Med
Medicine (General)
Translation:
Animals
Cells
PH
Public Health
Cantor H
. Reviving suppression? Nat Immunol. 2004 Apr; 5(4):347-9.
PMID:
15052259
.
Citations:
10
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Kissler S
, Lu L,
Cantor H
. Thymic selection can compensate for mutations affecting T cell activation and generate a normal T cell repertoire in mutant mice. Proc Natl Acad Sci U S A. 2004 Jan 06; 101(1):210-4.
PMID:
14694195
; PMCID:
PMC314164
.
Citations:
Fields:
Sci
Science
Translation:
Animals
Cells
Weber GF, Zawaideh S, Hikita S, Kumar VA,
Cantor H
, Ashkar S. Phosphorylation-dependent interaction of osteopontin with its receptors regulates macrophage migration and activation. J Leukoc Biol. 2002 Oct; 72(4):752-61.
PMID:
12377945
.
Citations:
92
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Yang XF, Ye Q, Press B, Han RZ, Bassing CH, Sleckman BP,
Alt FW
,
Cantor H
. Analysis of the complex genomic structure of Bcl-x and its relationship to Bcl-x(gamma) expression after CD28-dependent costimulation. Mol Immunol. 2002 Sep; 39(1-2):45-55.
PMID:
12213327
.
Citations:
6
Fields:
All
Allergy and Immunology
Mol
Molecular Biology
Translation:
Animals
Cells
Ye Q, Press B,
Kissler S
, Yang XF, Lu L, Bassing CH, Sleckman BP, Jansson M, Panoutsakopoulou V, Trimble LA,
Alt FW
,
Cantor H
. T cell costimulation through CD28 depends on induction of the Bcl-xgamma isoform: analysis of Bcl-xgamma-deficient mice. J Exp Med. 2002 Jul 01; 196(1):87-95.
PMID:
12093873
; PMCID:
PMC2194014
.
Citations:
6
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Animals
Cells
Trimble LA, Prince KA, Pestano GA, Daley J,
Cantor H
. Fas-dependent elimination of nonselected CD8 cells and lpr disease. J Immunol. 2002 May 15; 168(10):4960-7.
PMID:
11994447
.
Citations:
3
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Huster KM, Panoutsakopoulou V, Prince K, Sanchirico ME,
Cantor H
. T cell-dependent and -independent pathways to tissue destruction following herpes simplex virus-1 infection. Eur J Immunol. 2002 05; 32(5):1414-9.
PMID:
11981829
.
Citations:
8
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Weber GF,
Bronson RT
, Ilagan J,
Cantor H
, Schmits R, Mak TW. Absence of the CD44 gene prevents sarcoma metastasis. Cancer Res. 2002 Apr 15; 62(8):2281-6.
PMID:
11956084
.
Citations:
43
Fields:
Neo
Neoplasms
Translation:
Animals
Jansson M, Panoutsakopoulou V, Baker J, Klein L,
Cantor H
. Cutting edge: Attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin-deficient mice. J Immunol. 2002 Mar 01; 168(5):2096-9.
PMID:
11859094
.
Citations:
60
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Weber GF,
Cantor H
. Differential roles of osteopontin/Eta-1 in early and late lpr disease. Clin Exp Immunol. 2001 Dec; 126(3):578-83.
PMID:
11737079
; PMCID:
PMC1906233
.
Citations:
13
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Nguyen QD, Uy HS, Merchant A, Medina CA, Baltatzis S, Zhao T, Zhao ZS,
Cantor H
,
Foster CS
. Effect of Fas and Fas ligand deficiency in resistance of C57BL/6 mice to HSV-1 keratitis and chorioretinitis. Invest Ophthalmol Vis Sci. 2001 Oct; 42(11):2505-9.
PMID:
11581190
.
Citations:
2
Fields:
Oph
Ophthalmology
Translation:
Animals
Cells
Panoutsakopoulou V, Sanchirico ME, Huster KM, Jansson M, Granucci F, Shim DJ,
Wucherpfennig KW
,
Cantor H
. Analysis of the relationship between viral infection and autoimmune disease. Immunity. 2001 Jul; 15(1):137-47.
PMID:
11485745
.
Citations:
34
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Adler B, Ashkar S,
Cantor H
, Weber GF. Costimulation by extracellular matrix proteins determines the response to TCR ligation. Cell Immunol. 2001 May 25; 210(1):30-40.
PMID:
11485350
.
Citations:
9
Fields:
All
Allergy and Immunology
Cel
Cell Biology
Translation:
Animals
Cells
Panoutsakopoulou V,
Cantor H
. On the relationship between viral infection and autoimmunity. J Autoimmun. 2001 May; 16(3):341-5.
PMID:
11334502
.
Citations:
5
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Suri-Payer E,
Cantor H
. Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J Autoimmun. 2001 Mar; 16(2):115-23.
PMID:
11247637
.
Citations:
64
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Wang R, Ramaswamy S, Hu D,
Cantor H
. Definition of a novel binding site on CD8 cells for a conserved region of the MHC class Ib molecule Qa-1 that regulates IFN-gamma expression. Eur J Immunol. 2001 Jan; 31(1):87-93.
PMID:
11169442
.
Citations:
5
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Jansson M, Zawaideh S,
Rittling SR
, Denhardt DT, Glimcher MJ,
Cantor H
. Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science. 2000 Feb 04; 287(5454):860-4.
PMID:
10657301
.
Citations:
325
Fields:
Sci
Science
Translation:
Animals
Cells
Cantor H
. T-cell receptor crossreactivity and autoimmune disease. Adv Immunol. 2000; 75:209-33.
PMID:
10879285
.
Citations:
7
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Pestano GA, Zhou Y, Trimble LA, Daley J, Weber GF,
Cantor H
. Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death. Science. 1999 May 14; 284(5417):1187-91.
PMID:
10325233
.
Citations:
20
Fields:
Sci
Science
Translation:
Animals
Cells
Adler B, Weber GF,
Cantor H
. Activation of T cells by superantigen: cytokine production but not apoptosis depends on MEK-1 activity. Eur J Immunol. 1998 11; 28(11):3749-54.
PMID:
9842917
.
Citations:
4
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Zhao ZS, Granucci F, Yeh L, Schaffer PA,
Cantor H
. Molecular mimicry by herpes simplex virus-type 1: autoimmune disease after viral infection. Science. 1998 Feb 27; 279(5355):1344-7.
PMID:
9478893
.
Citations:
133
Fields:
Sci
Science
Translation:
Animals
Cells
Noble A, Pestano GA,
Cantor H
. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. J Immunol. 1998 Jan 15; 160(2):559-65.
PMID:
9551888
.
Citations:
16
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Noble A, Zhao ZS,
Cantor H
. Suppression of immune responses by CD8 cells. II. Qa-1 on activated B cells stimulates CD8 cell suppression of T helper 2 responses. J Immunol. 1998 Jan 15; 160(2):566-71.
PMID:
9551889
.
Citations:
36
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Yang XF, Weber GF,
Cantor H
. A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells. Immunity. 1997 Nov; 7(5):629-39.
PMID:
9390687
; PMCID:
PMC3908546
.
Citations:
34
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Weber GF, Mirza NM,
Yunis EJ
, Dubey D,
Cantor H
. Localization and treatment of an oxidation-sensitive defect within the TCR-coupled signalling pathway that is associated with normal and premature immunologic aging. Growth Dev Aging. 1997 Fall-Winter; 61(3-4):191-207.
PMID:
9546110
.
Citations:
Fields:
Phy
Physiology
Translation:
Animals
Cells
Weber GF, Daley J, Kraeft SK, Chen LB,
Cantor H
. Measurement of apoptosis in heterogenous cell populations. Cytometry. 1997 Feb 01; 27(2):136-44.
PMID:
9012380
.
Citations:
2
Fields:
Cel
Cell Biology
Translation:
Animals
Cells
Weber GF, Ashkar S,
Cantor H
. Interaction between CD44 and osteopontin as a potential basis for metastasis formation. Proc Assoc Am Physicians. 1997 Jan; 109(1):1-9.
PMID:
9010911
.
Citations:
33
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Weber GF,
Cantor H
. The immunology of Eta-1/osteopontin. Cytokine Growth Factor Rev. 1996 Oct; 7(3):241-8.
PMID:
8971479
.
Citations:
35
Fields:
All
Allergy and Immunology
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Weber GF, Ashkar S, Glimcher MJ,
Cantor H
. Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science. 1996 Jan 26; 271(5248):509-12.
PMID:
8560266
.
Citations:
245
Fields:
Sci
Science
Translation:
Animals
Cells
Avery AC, Zhao ZS, Rodriguez A, Bikoff EK, Soheilian M,
Foster CS
,
Cantor H
. Resistance to herpes stromal keratitis conferred by an IgG2a-derived peptide. Nature. 1995 Aug 03; 376(6539):431-4.
PMID:
7630419
.
Citations:
18
Fields:
Sci
Science
Translation:
Animals
Cells
Cantor H
. The role of Eta-1/osteopontin in the pathogenesis of immunological disorders. Ann N Y Acad Sci. 1995 Apr 21; 760:143-50.
PMID:
7785892
.
Citations:
9
Fields:
Sci
Science
Translation:
Animals
Cells
Weber GF, Abromson-Leeman S,
Cantor H
. A signaling pathway coupled to T cell receptor ligation by MMTV superantigen leading to transient activation and programmed cell death. Immunity. 1995 Apr; 2(4):363-72.
PMID:
7719939
.
Citations:
8
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Avery AC, Markowitz JS,
Grusby MJ
,
Glimcher LH
,
Cantor H
. Activation of T cells by superantigen in class II-negative mice. J Immunol. 1994 Dec 01; 153(11):4853-61.
PMID:
7963549
.
Citations:
12
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Weber GF,
Cantor H
. Phosphatidylinositol synthesis is a proximal event in intracellular signaling coupled to T cell receptor ligation. Differential induction by conventional antigen and retroviral superantigen. J Immunol. 1994 May 01; 152(9):4433-43.
PMID:
7908918
.
Citations:
3
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Crump AL,
Grusby MJ
,
Glimcher LH
,
Cantor H
. Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10739-43.
PMID:
7902569
; PMCID:
PMC47853
.
Citations:
15
Fields:
Sci
Science
Translation:
Animals
Cells
Weber GF,
Cantor H
. HIV glycoprotein as a superantigen. A mechanism of autoimmunity and implications for a vaccination strategy. Med Hypotheses. 1993 Sep; 41(3):247-50.
PMID:
8259084
.
Citations:
4
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
PH
Public Health
Patarca R, Fletcher MA,
Cantor H
. Structural features of two T-cell-specific genes that suggest a potential role in HTLV-I-associated pathology. AIDS Res Hum Retroviruses. 1993 Feb; 9(2):105-7.
PMID:
8096144
.
Citations:
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Animals
Cells
Cantor H
, Crump AL, Raman VK, Liu H, Markowitz JS,
Grusby MJ
,
Glimcher LH
. Immunoregulatory effects of superantigens: interactions of staphyloc