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Gary Richard Strichartz, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01GM064792 (STRICHARTZ, GARY R) Jul 1, 2002 - Jun 30, 2007
    NIH/NIGMS
    Local Anesthetic Interactions with Membranes
    Role: Principal Investigator
  2. R01CA080153 (STRICHARTZ, GARY R) Jul 16, 1999 - May 31, 2015
    NIH/NCI
    Endothelin Mechanisms in Metastic Prostate Cancer Pain
    Role: Principal Investigator
  3. R56CA080153 (STRICHARTZ, GARY R) Jul 16, 1999 - Jul 31, 2010
    NIH/NCI
    Endothelin mechanisms in metastic prostate cancer pain
    Role: Principal Investigator
  4. R01GM035647 (STRICHARTZ, GARY R) Feb 1, 1985 - Jun 30, 2002
    NIH/NIGMS
    CONTROL OF NEURAL FUNCTION IN ANESTHESIA
    Role: Principal Investigator
  5. P50GM015904 (MILLER, KEITH W) Jan 1, 1978 - Dec 31, 1998
    NIH/NIGMS
    ANESTHESIOLOGY CENTER FOR TEACHING AND RESEARCH
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nandi M, Schreiber KL, Martel MO, Cornelius M, Campbell CM, Haythornthwaite JA, Smith MT, Wright J, Aglio LS, Strichartz G, Edwards RR. Sex differences in negative affect and postoperative pain in patients undergoing total knee arthroplasty. Biol Sex Differ. 2019 May 06; 10(1):23. PMID: 31060622.
    Citations:    
  2. Zeballos JL, Strichartz GR. Tuning Up the Life Saver: An Experimental Approach to Optimizing the Delivery of Intravenous Lipid Emulsions. Anesth Analg. 2019 Feb; 128(2):199-201. PMID: 30649040.
    Citations:    Fields:    
  3. Schreiber KL, Zinboonyahgoon N, Xu X, Spivey T, King T, Dominici L, Partridge A, Golshan M, Strichartz G, Edwards RR. Preoperative Psychosocial and Psychophysical Phenotypes as Predictors of Acute Pain Outcomes After Breast Surgery. J Pain. 2019 May; 20(5):540-556. PMID: 30476655.
    Citations:    Fields:    
  4. Hamaya C, Barr T, Strichartz GR. Multiple Inhibitory Mechanisms of Lidocaine on Bradykinin Receptor Activity in Model Sensory Neurons. Reg Anesth Pain Med. 2018 Aug; 43(6):605-612. PMID: 29557886.
    Citations:    Fields:    Translation:AnimalsCells
  5. Khodorova A, Zhang Y, Nicol G, Strichartz G. Interactions of peripheral endothelin-1 and nerve growth factor as contributors to persistent cutaneous pain. Physiol Res. 2018 Jun 27; 67(Supplementum 1):S215-S225. PMID: 29947541.
    Citations:    Fields:    Translation:AnimalsCells
  6. Ende HB, Soens MA, Nandi M, Strichartz GR, Schreiber KL. Association of Interindividual Variation in Plasma Oxytocin With Postcesarean Incisional Pain. Anesth Analg. 2018 Jun 14. PMID: 29916862.
    Citations:    Fields:    
  7. Lirk P, Hollmann MW, Strichartz G. The Science of Local Anesthesia: Basic Research, Clinical Application, and Future Directions. Anesth Analg. 2018 04; 126(4):1381-1392. PMID: 29189280.
    Citations:    Fields:    
  8. Kays J, Zhang YH, Khorodova A, Strichartz G, Nicol GD. Peripheral Synthesis of an Atypical Protein Kinase C Mediates the Enhancement of Excitability and the Development of Mechanical Hyperalgesia Produced by Nerve Growth Factor. Neuroscience. 2018 02 10; 371:420-432. PMID: 29288797.
    Citations:    Fields:    Translation:AnimalsCells
  9. Strichartz GR. The Trip. Anesthesiology. 2017 Dec; 127(6):1035-1036. PMID: 28837435.
    Citations:    
  10. Khasabov SG, Wang JC, Simone DA, Strichartz GR. A role for neurokinin-1 receptor neurons in the rostral ventromedial medulla in the development of chronic postthoracotomy pain. Pain. 2017 07; 158(7):1332-1341. PMID: 28622274.
    Citations:    Fields:    Translation:AnimalsCells
  11. Khasabov SG, Chi-Fei Wang J, Simone DA, Strichartz GR. A role for nk-1 neurons in the rostral ventromedial medulla in the development of chronic post-thoracotomy pain. Pain. 2017 Apr 05. PMID: 28394854.
    Citations:    Fields:    
  12. Wang JC, Strichartz GR. Prevention of Chronic Post-Thoracotomy Pain in Rats By Intrathecal Resolvin D1 and D2: Effectiveness of Perioperative and Delayed Drug Delivery. J Pain. 2017 05; 18(5):535-545. PMID: 28063958.
    Citations: 3     Fields:    Translation:Animals
  13. Khodorova A, Nicol GD, Strichartz G. The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor. Neuroscience. 2017 01 06; 340:384-397. PMID: 27826102.
    Citations: 3     Fields:    Translation:Animals
  14. Nandi M, Cornelius M, Campbell C, Smith M, Haythornthwaite J, Wright J, Edwards R, Strichartz G. (103) Sex differences in pain and functioning among Total Knee Arthroplasty patients. J Pain. 2016 Apr; 17(4S):S1-S2. PMID: 28162297.
    Citations:    
  15. Wang CF, Russell G, Wang SY, Strichartz GR, Wang GK. R-Duloxetine and N-Methyl Duloxetine as Novel Analgesics Against Experimental Postincisional Pain. Anesth Analg. 2016 Mar; 122(3):719-29. PMID: 26646348.
    Citations: 2     Fields:    Translation:AnimalsCells
  16. Rathmell JP, Strichartz G, Wanderer J. Neosaxitoxin versus Traditional Local Anesthetics: Mechanism of Action and Sites of Notable Effect. Anesthesiology. 2015 Oct; 123(4):A23. PMID: 26372144.
    Citations:    Fields:    Translation:HumansCells
  17. Strichartz GR, Khodorova A, Wang JC, Chen YW, Huang CC. Contralateral Hyperalgesia from Injection of Endothelin-1 into the Ipsilateral Paw Requires Efferent Conduction into the Contralateral Paw. Anesth Analg. 2015 Oct; 121(4):1065-77. PMID: 26218866.
    Citations:    Fields:    Translation:AnimalsCells
  18. Soens M, Wang JC, Berta T, Strichartz G. Systemic Progesterone Administration in Early Life Alters the Hyperalgesic Responses to Surgery in the Adult: A Study on Female Rats. Anesth Analg. 2015 Aug; 121(2):545-55. PMID: 26076389.
    Citations:    Fields:    Translation:AnimalsCells
  19. Wang CF, Russell G, Strichartz GR, Wang GK. The Local and Systemic Actions of Duloxetine in Allodynia and Hyperalgesia Using a Rat Skin Incision Pain Model. Anesth Analg. 2015 Aug; 121(2):532-44. PMID: 26049779.
    Citations: 1     Fields:    Translation:AnimalsCells
  20. Hung CH, Wang JC, Strichartz GR. Spontaneous Chronic Pain After Experimental Thoracotomy Revealed by Conditioned Place Preference: Morphine Differentiates Tactile Evoked Pain From Spontaneous Pain. J Pain. 2015 Sep; 16(9):903-12. PMID: 26116369.
    Citations: 3     Fields:    Translation:Animals
  21. Strichartz GR, Wang JC, Blaskovich P, Ohri R. Mitigation of experimental, chronic post-thoracotomy pain by preoperative infiltration of local slow-release bupivacaine microspheres. Anesth Analg. 2015 Jun; 120(6):1375-84. PMID: 25902323.
    Citations:    Fields:    Translation:Animals
  22. Cassinello F, Prieto I, del Olmo M, Rivas S, Strichartz GR. Cancer surgery: how may anesthesia influence outcome? J Clin Anesth. 2015 May; 27(3):262-72. PMID: 25769963.
    Citations: 11     Fields:    Translation:Humans
  23. Makdessi MJ, Barr TP, Xue W, Strichartz GR. Bupivacaine inhibits endothelin-1-evoked increases in intracellular calcium in model sensory neurons. Acta Anaesthesiol Scand. 2015 Aug; 59(7):936-45. PMID: 25684033.
    Citations:    Fields:    Translation:AnimalsCells
  24. Schmidt B, Ohri R, Wang JC, Blaskovich P, Kesselring A, Scarborough N, Herman C, Strichartz G. Local pathology and systemic serum bupivacaine after subcutaneous delivery of slow-releasing bupivacaine microspheres. Anesth Analg. 2015 Jan; 120(1):36-44. PMID: 25360482.
    Citations: 2     Fields:    Translation:Animals
  25. Forman SA, Miller KW, Talmor D, Hickey P, Strichartz G, Wiener-Kronish J. Research at the Harvard Anesthesia Departments. Anesthesiology. 2014 Dec; 121(6):1141-3. PMID: 25299744.
    Citations:    Fields:    Translation:Humans
  26. Barr TP, Kornberg D, Montmayeur JP, Long M, Reichheld S, Strichartz GR. Validation of endothelin B receptor antibodies reveals two distinct receptor-related bands on Western blot. Anal Biochem. 2015 01 01; 468:28-33. PMID: 25232999.
    Citations:    Fields:    Translation:HumansAnimalsCells
  27. Ohri R, Wang JC, Pham L, Blaskovich PD, Costa D, Nichols G, Hildebrand W, Scarborough N, Herman C, Strichartz GR. Prolonged amelioration of experimental postoperative pain by bupivacaine released from microsphere-coated hernia mesh. Reg Anesth Pain Med. 2014 Mar-Apr; 39(2):97-107. PMID: 24513957.
    Citations: 1     Fields:    Translation:Animals
  28. Barr TP, Hrnjic A, Khodorova A, Sprague JM, Strichartz GR. Sensitization of cutaneous neuronal purinergic receptors contributes to endothelin-1-induced mechanical hypersensitivity. Pain. 2014 Jun; 155(6):1091-101. PMID: 24569146.
    Citations: 8     Fields:    Translation:AnimalsCells
  29. Khodorova A, Nicol GD, Strichartz G. The p75NTR signaling cascade mediates mechanical hyperalgesia induced by nerve growth factor injected into the rat hind paw. Neuroscience. 2013 Dec 19; 254:312-23. PMID: 24095693.
    Citations: 6     Fields:    Translation:AnimalsCells
  30. Ohri R, Wang JC, Blaskovich PD, Pham LN, Costa DS, Nichols GA, Hildebrand WP, Scarborough NL, Herman CJ, Strichartz GR. Inhibition by local bupivacaine-releasing microspheres of acute postoperative pain from hairy skin incision. Anesth Analg. 2013 Sep; 117(3):717-30. PMID: 23921651.
    Citations: 7     Fields:    Translation:Animals
  31. Barr TP, Albrecht PJ, Hou Q, Mongin AA, Strichartz GR, Rice FL. Air-stimulated ATP release from keratinocytes occurs through connexin hemichannels. PLoS One. 2013; 8(2):e56744. PMID: 23457608.
    Citations: 16     Fields:    Translation:HumansCells
  32. Barreveld A, Witte J, Chahal H, Durieux ME, Strichartz G. Preventive analgesia by local anesthetics: the reduction of postoperative pain by peripheral nerve blocks and intravenous drugs. Anesth Analg. 2013 May; 116(5):1141-61. PMID: 23408672.
    Citations: 7     Fields:    Translation:Humans
  33. Leeson S, Strichartz G. Kinetics of uptake and washout of lidocaine in rat sciatic nerve in vitro. Anesth Analg. 2013 Mar; 116(3):694-702. PMID: 23400993.
    Citations:    Fields:    Translation:Animals
  34. Chi-Fei Wang J, Hung CH, Gerner P, Ji RR, Strichartz GR. The Qualitative Hyperalgesia Profile: A New Metric to Assess Chronic Post-Thoracotomy Pain. Open Pain J. 2013; 6:190-198. PMID: 24567767.
    Citations: 2     
  35. Ohri R, Blaskovich P, Wang JC, Pham L, Nichols G, Hildebrand W, Costa D, Scarborough N, Herman C, Strichartz G. Prolonged nerve block by microencapsulated bupivacaine prevents acute postoperative pain in rats. Reg Anesth Pain Med. 2012 Nov-Dec; 37(6):607-15. PMID: 22996201.
    Citations: 1     Fields:    Translation:Animals
  36. Wang GK, Strichartz GR. State-Dependent Inhibition of Sodium Channels by Local Anesthetics: A 40-Year Evolution. Biochem (Mosc) Suppl Ser A Membr Cell Biol. 2012 Apr; 6(2):120-127. PMID: 23710324.
    Citations: 8     
  37. Huang L, Gao YJ, Wang J, Strichartz G. Shifts in cell-type expression accompany a diminishing role of spinal p38-mapkinase activation over time during prolonged postoperative pain. Anesthesiology. 2011 Dec; 115(6):1281-90. PMID: 21975276.
    Citations: 5     Fields:    Translation:AnimalsCells
  38. Ji RR, Xu ZZ, Strichartz G, Serhan CN. Emerging roles of resolvins in the resolution of inflammation and pain. Trends Neurosci. 2011 Nov; 34(11):599-609. PMID: 21963090.
    Citations: 88     Fields:    Translation:HumansAnimalsCells
  39. Colvin AC, Wang CF, Soens MA, Mitani AA, Strichartz G, Gerner P. Prolonged cutaneous analgesia with transdermal application of amitriptyline and capsaicin. Reg Anesth Pain Med. 2011 May-Jun; 36(3):236-40. PMID: 21364497.
    Citations: 3     Fields:    Translation:Animals
  40. Montmayeur JP, Barr TP, Kam SA, Packer SJ, Strichartz GR. ET-1 induced Elevation of intracellular calcium in clonal neuronal and embryonic kidney cells involves endogenous endothelin-A receptors linked to phospholipase C through Ga(q/11). Pharmacol Res. 2011 Sep; 64(3):258-67. PMID: 21515378.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  41. Barr TP, Kam S, Khodorova A, Montmayeur JP, Strichartz GR. New perspectives on the endothelin axis in pain. Pharmacol Res. 2011 Jun; 63(6):532-40. PMID: 21352917.
    Citations: 10     Fields:    Translation:HumansCells
  42. Huang L, Wang CF, Serhan CN, Strichartz G. Enduring prevention and transient reduction of postoperative pain by intrathecal resolvin D1. Pain. 2011 Mar; 152(3):557-65. PMID: 21255928.
    Citations: 27     Fields:    Translation:Animals
  43. Wang CF, Pancaro C, Gerner P, Strichartz G. Prolonged suppression of postincisional pain by a slow-release formulation of lidocaine. Anesthesiology. 2011 Jan; 114(1):135-49. PMID: 21169797.
    Citations: 9     Fields:    Translation:Animals
  44. Gerner P, Wang CF, Lee BS, Suzuki S, Degirolami U, Gandhi A, Knaack D, Strichartz G. The relationship between functional sciatic nerve block duration and the rate of release of lidocaine from a controlled-release matrix. Anesth Analg. 2010 Jul; 111(1):221-9. PMID: 20522702.
    Citations: 7     Fields:    Translation:AnimalsCells
  45. Khodorova A, Strichartz GR. Remarkably long-lasting tachyphylaxis of pain responses to ET-1: evidence against central nervous system involvement. Can J Physiol Pharmacol. 2010 Jun; 88(6):668-75. PMID: 20628433.
    Citations: 1     Fields:    Translation:Animals
  46. Khodorova A, Strichartz GR. Contralateral paw sensitization following injection of endothelin-1: effects of local anesthetics differentiate peripheral and central processes. Neuroscience. 2010 Jan 20; 165(2):553-60. PMID: 19874873.
    Citations: 2     Fields:    Translation:AnimalsCells
  47. Strichartz G. Beyond neurons: the complex sources of pain transduction. Pain. 2010 Feb; 148(2):180-1. PMID: 19917519.
    Citations:    Fields:    Translation:AnimalsCells
  48. Colucci V, Strichartz G, Jolesz F, Vykhodtseva N, Hynynen K. Focused ultrasound effects on nerve action potential in vitro. Ultrasound Med Biol. 2009 Oct; 35(10):1737-47. PMID: 19647923.
    Citations: 19     Fields:    Translation:Animals
  49. Khodorova A, Richter J, Vasko MR, Strichartz G. Early and late contributions of glutamate and CGRP to mechanical sensitization by endothelin-1. J Pain. 2009 Jul; 10(7):740-9. PMID: 19559390.
    Citations: 6     Fields:    Translation:AnimalsCells
  50. Shrestha S, Gracias NG, Mujenda F, Khodorova A, Vasko MR, Strichartz GR. Local antinociception induced by endothelin-1 in the hairy skin of the rat's back. J Pain. 2009 Jul; 10(7):702-14. PMID: 19559389.
    Citations: 8     Fields:    Translation:Animals
  51. Feng B, Strichartz G. Endothelin-1 raises excitability and reduces potassium currents in sensory neurons. Brain Res Bull. 2009 Aug 14; 79(6):345-50. PMID: 19409452.
    Citations: 8     Fields:    Translation:AnimalsCells
  52. Wang CF, Djalali AG, Gandhi A, Knaack D, De Girolami U, Strichartz G, Gerner P. An absorbable local anesthetic matrix provides several days of functional sciatic nerve blockade. Anesth Analg. 2009 Mar; 108(3):1027-33. PMID: 19224820.
    Citations: 11     Fields:    Translation:Animals
  53. Khodorova A, Zou S, Ren K, Dubner R, Davar G, Strichartz G. Dual Roles for Endothelin-B Receptors in Modulating Adjuvant-Induced Inflammatory Hyperalgesia in Rats. Open Pain J. 2009; 2:30-40. PMID: 20559459.
    Citations: 9     
  54. Khodorova A, Montmayeur JP, Strichartz G. Endothelin receptors and pain. J Pain. 2009 Jan; 10(1):4-28. PMID: 19111868.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  55. Hans G, Schmidt BL, Strichartz G. Nociceptive sensitization by endothelin-1. Brain Res Rev. 2009 Apr; 60(1):36-42. PMID: 19150466.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  56. Ji RR, Gereau RW, Malcangio M, Strichartz GR. MAP kinase and pain. Brain Res Rev. 2009 Apr; 60(1):135-48. PMID: 19150373.
    Citations: 279     Fields:    Translation:HumansAnimalsCells
  57. Kamath R, Strichartz G, Rosenthal D. Cartilage toxicity from local anesthetics. Skeletal Radiol. 2008 Oct; 37(10):871-3. PMID: 18685843.
    Citations: 3     Fields:    Translation:Humans
  58. Sugimoto K, Kissin I, Strichartz G. A high concentration of resiniferatoxin inhibits ion channel function in clonal neuroendocrine cells. Anesth Analg. 2008 Jul; 107(1):318-24. PMID: 18635503.
    Citations: 1     Fields:    Translation:AnimalsCells
  59. Strichartz GR. Novel ideas of local anaesthetic actions on various ion channels to ameliorate postoperative pain. Br J Anaesth. 2008 Jul; 101(1):45-7. PMID: 18487246.
    Citations: 6     Fields:    Translation:HumansAnimals
  60. Gerner P, Strichartz GR. Sensory and motor complications of local anesthetics. Muscle Nerve. 2008 Apr; 37(4):421-5. PMID: 18236466.
    Citations: 4     Fields:    Translation:HumansCells
  61. McNally MA, Baek RC, Avila RL, Seyfried TN, Strichartz GR, Kirschner DA. Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis. J Negat Results Biomed. 2007 Jul 10; 6:8. PMID: 17623103.
    Citations: 3     Fields:    Translation:AnimalsCells
  62. Mujenda FH, Duarte AM, Reilly EK, Strichartz GR. Cutaneous endothelin-A receptors elevate post-incisional pain. Pain. 2007 Dec 15; 133(1-3):161-73. PMID: 17467172.
    Citations: 13     Fields:    Translation:Animals
  63. Zhang J, Hadlock T, Gent A, Strichartz GR. Tetracaine-membrane interactions: effects of lipid composition and phase on drug partitioning, location, and ionization. Biophys J. 2007 Jun 01; 92(11):3988-4001. PMID: 17351014.
    Citations: 14     Fields:    Translation:Cells
  64. Yanagidate F, Strichartz GR. Local anesthetics. Handb Exp Pharmacol. 2007; (177):95-127. PMID: 17087121.
    Citations: 8     Fields:    Translation:HumansAnimals
  65. Weinberg GL, Ripper R, Murphy P, Edelman LB, Hoffman W, Strichartz G, Feinstein DL. Lipid infusion accelerates removal of bupivacaine and recovery from bupivacaine toxicity in the isolated rat heart. Reg Anesth Pain Med. 2006 Jul-Aug; 31(4):296-303. PMID: 16857549.
    Citations: 28     Fields:    Translation:Animals
  66. Balonov K, Khodorova A, Strichartz GR. Tactile allodynia initiated by local subcutaneous endothelin-1 is prolonged by activation of TRPV-1 receptors. Exp Biol Med (Maywood). 2006 Jun; 231(6):1165-70. PMID: 16741070.
    Citations: 19     Fields:    Translation:AnimalsCells
  67. Amir R, Argoff CE, Bennett GJ, Cummins TR, Durieux ME, Gerner P, Gold MS, Porreca F, Strichartz GR. The role of sodium channels in chronic inflammatory and neuropathic pain. J Pain. 2006 May; 7(5 Suppl 3):S1-29. PMID: 16632328.
    Citations: 69     Fields:    Translation:HumansCells
  68. Yanagidate F, Strichartz GR. Bupivacaine inhibits activation of neuronal spinal extracellular receptor-activated kinase through selective effects on ionotropic receptors. Anesthesiology. 2006 Apr; 104(4):805-14. PMID: 16571978.
    Citations: 5     Fields:    Translation:Animals
  69. Zhuang ZY, Wen YR, Zhang DR, Borsello T, Bonny C, Strichartz GR, Decosterd I, Ji RR. A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance. J Neurosci. 2006 Mar 29; 26(13):3551-60. PMID: 16571763.
    Citations: 150     Fields:    Translation:AnimalsCells
  70. Duarte AM, Pospisilova E, Reilly E, Mujenda F, Hamaya Y, Strichartz GR. Reduction of postincisional allodynia by subcutaneous bupivacaine: findings with a new model in the hairy skin of the rat. Anesthesiology. 2005 Jul; 103(1):113-25. PMID: 15983463.
    Citations: 24     Fields:    Translation:Animals
  71. Lambert DH, Strichartz GR. In defense of in vitro findings. Anesthesiology. 2004 Nov; 101(5):1246-7; author reply 1247-8. PMID: 15505475.
    Citations:    Fields:    Translation:HumansCells
  72. Lambert DH, Lambert LA, Strichartz GR. Questioning the mechanism of nerve injury. Anesthesiology. 2004 Nov; 101(5):1249; author reply 1249-50. PMID: 15505479.
    Citations:    Fields:    Translation:AnimalsCells
  73. Ji RR, Strichartz G. Cell signaling and the genesis of neuropathic pain. Sci STKE. 2004 Sep 21; 2004(252):reE14. PMID: 15454629.
    Citations: 92     Fields:    Translation:HumansAnimalsCells
  74. Son SL, Wong K, Strichartz G. Antagonism by local anesthetics of sodium channel activators in the presence of scorpion toxins: two mechanisms for competitive inhibition. Cell Mol Neurobiol. 2004 Aug; 24(4):565-77. PMID: 15233379.
    Citations: 2     Fields:    Translation:AnimalsCells
  75. Houck CS, Khodorova A, Reale AM, Strichartz GR, Davar G. Sensory fibers resistant to the actions of tetrodotoxin mediate nocifensive responses to local administration of endothelin-1 in rats. Pain. 2004 Aug; 110(3):719-26. PMID: 15288413.
    Citations: 13     Fields:    Translation:AnimalsCells
  76. Nakamura T, Popitz-Bergez F, Birknes J, Strichartz GR. The critical role of concentration for lidocaine block of peripheral nerve in vivo: studies of function and drug uptake in the rat. Anesthesiology. 2003 Nov; 99(5):1189-97. PMID: 14576558.
    Citations: 15     Fields:    Translation:Animals
  77. Sinnott CJ, Strichartz GR. Levobupivacaine versus ropivacaine for sciatic nerve block in the rat. Reg Anesth Pain Med. 2003 Jul-Aug; 28(4):294-303. PMID: 12945022.
    Citations: 3     Fields:    Translation:Animals
  78. Khodorova A, Navarro B, Jouaville LS, Murphy JE, Rice FL, Mazurkiewicz JE, Long-Woodward D, Stoffel M, Strichartz GR, Yukhananov R, Davar G. Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury. Nat Med. 2003 Aug; 9(8):1055-61. PMID: 12847519.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  79. Araujo MC, Sinnott CJ, Strichartz GR. Multiple phases of relief from experimental mechanical allodynia by systemic lidocaine: responses to early and late infusions. Pain. 2003 May; 103(1-2):21-9. PMID: 12749955.
    Citations: 16     Fields:    Translation:Animals
  80. Taheri S, Cogswell LP, Gent A, Strichartz GR. Hydrophobic and ionic factors in the binding of local anesthetics to the major variant of human alpha1-acid glycoprotein. J Pharmacol Exp Ther. 2003 Jan; 304(1):71-80. PMID: 12490577.
    Citations: 6     Fields:    Translation:HumansCells
  81. Sinnott CJ, Cogswell III LP, Johnson A, Strichartz GR. On the mechanism by which epinephrine potentiates lidocaine's peripheral nerve block. Anesthesiology. 2003 Jan; 98(1):181-8. PMID: 12502995.
    Citations: 9     Fields:    Translation:Animals
  82. Persaud N, Strichartz GR. Micromolar lidocaine selectively blocks propagating ectopic impulses at a distance from their site of origin. Pain. 2002 Sep; 99(1-2):333-40. PMID: 12237212.
    Citations: 10     Fields:    Translation:Animals
  83. Khodorova A, Fareed MU, Gokin A, Strichartz GR, Davar G. Local injection of a selective endothelin-B receptor agonist inhibits endothelin-1-induced pain-like behavior and excitation of nociceptors in a naloxone-sensitive manner. J Neurosci. 2002 Sep 01; 22(17):7788-96. PMID: 12196602.
    Citations: 23     Fields:    Translation:AnimalsCells
  84. Zhou Z, Davar G, Strichartz G. Endothelin-1 (ET-1) selectively enhances the activation gating of slowly inactivating tetrodotoxin-resistant sodium currents in rat sensory neurons: a mechanism for the pain-inducing actions of ET-1. J Neurosci. 2002 Aug 01; 22(15):6325-30. PMID: 12151509.
    Citations: 27     Fields:    Translation:AnimalsCells
  85. Nau C, Strichartz GR. Drug chirality in anesthesia. Anesthesiology. 2002 Aug; 97(2):497-502. PMID: 12151942.
    Citations: 6     Fields:    Translation:AnimalsCells
  86. Strichartz GR, Zhou Z, Sinnott C, Khodorova A. Therapeutic concentrations of local anaesthetics unveil the potential role of sodium channels in neuropathic pain. Novartis Found Symp. 2002; 241:189-201; discussion 202-5, 226-32. PMID: 11771646.
    Citations: 3     Fields:    Translation:HumansAnimals
  87. Zhou QL, Strichartz G, Davar G. Endothelin-1 activates ET(A) receptors to increase intracellular calcium in model sensory neurons. Neuroreport. 2001 Dec 04; 12(17):3853-7. PMID: 11726808.
    Citations: 16     Fields:    Translation:AnimalsCells
  88. Gokin AP, Philip B, Strichartz GR. Preferential block of small myelinated sensory and motor fibers by lidocaine: in vivo electrophysiology in the rat sciatic nerve. Anesthesiology. 2001 Dec; 95(6):1441-54. PMID: 11748404.
    Citations: 18     Fields:    Translation:AnimalsCells
  89. Cogswell LP, Raines DE, Parekh S, Jonas O, Maggio JE, Strichartz GR. Development of a novel probe for measuring drug binding to the F1*S variant of human alpha 1-acid glycoprotein. J Pharm Sci. 2001 Sep; 90(9):1407-23. PMID: 11745793.
    Citations:    Fields:    Translation:HumansCells
  90. Gokin AP, Fareed MU, Pan HL, Hans G, Strichartz GR, Davar G. Local injection of endothelin-1 produces pain-like behavior and excitation of nociceptors in rats. J Neurosci. 2001 Jul 15; 21(14):5358-66. PMID: 11438612.
    Citations: 46     Fields:    Translation:AnimalsCells
  91. Khodorova A, Meissner K, Leeson S, Strichartz GR. Lidocaine selectively blocks abnormal impulses arising from noninactivating Na channels. Muscle Nerve. 2001 May; 24(5):634-47. PMID: 11317273.
    Citations: 3     Fields:    Translation:AnimalsCells
  92. Nau C, Wang SY, Strichartz GR, Wang GK. Block of human heart hH1 sodium channels by the enantiomers of bupivacaine. Anesthesiology. 2000 Oct; 93(4):1022-33. PMID: 11020758.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  93. Sinnott CJ, Garfield JM, Thalhammer JG, Strichartz GR. Addition of sodium bicarbonate to lidocaine decreases the duration of peripheral nerve block in the rat. Anesthesiology. 2000 Oct; 93(4):1045-52. PMID: 11020760.
    Citations: 6     Fields:    Translation:Animals
  94. Strichartz G. Pathways and obstacles to local anesthesia, a personal account: the 2000 Gaston Labat lecture. Reg Anesth Pain Med. 2000 Sep-Oct; 25(5):447-51. PMID: 11009228.
    Citations: 1     Fields:    Translation:Humans
  95. Vladimirov M, Nau C, Mok WM, Strichartz G. Potency of bupivacaine stereoisomers tested in vitro and in vivo: biochemical, electrophysiological, and neurobehavioral studies. Anesthesiology. 2000 Sep; 93(3):744-55. PMID: 10969308.
    Citations: 6     Fields:    Translation:AnimalsCells
  96. Khodorova AB, Strichartz GR. The addition of dilute epinephrine produces equieffectiveness of bupivacaine enantiomers for cutaneous analgesia in the rat. Anesth Analg. 2000 Aug; 91(2):410-6. PMID: 10910859.
    Citations: 3     Fields:    Translation:Animals
  97. Chamberlain LJ, Yannas IV, Hsu HP, Strichartz GR, Spector M. Near-terminus axonal structure and function following rat sciatic nerve regeneration through a collagen-GAG matrix in a ten-millimeter gap. J Neurosci Res. 2000 Jun 01; 60(5):666-77. PMID: 10820438.
    Citations: 13     Fields:    Translation:AnimalsCells
  98. Kohane DS, Lu NT, Gökgöl-Kline AC, Shubina M, Kuang Y, Hall S, Strichartz GR, Berde CB. The local anesthetic properties and toxicity of saxitonin homologues for rat sciatic nerve block in vivo. Reg Anesth Pain Med. 2000 Jan-Feb; 25(1):52-9. PMID: 10660241.
    Citations: 14     Fields:    Translation:AnimalsCells
  99. Moller RA, Datta S, Strichartz GR. Beta-estradiol acutely potentiates the depression of cardiac excitability by lidocaine and bupivacaine. J Cardiovasc Pharmacol. 1999 Nov; 34(5):718-27. PMID: 10547089.
    Citations: 2     Fields:    Translation:Animals
  100. Nau C, Wang SY, Strichartz GR, Wang GK. Point mutations at N434 in D1-S6 of mu1 Na(+) channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers. Mol Pharmacol. 1999 Aug; 56(2):404-13. PMID: 10419561.
    Citations: 37     Fields:    Translation:HumansCells
  101. Sinnott CJ, Garfield JM, Strichartz GR. Differential efficacy of intravenous lidocaine in alleviating ipsilateral versus contralateral neuropathic pain in the rat. Pain. 1999 Apr; 80(3):521-31. PMID: 10342413.
    Citations: 15     Fields:    Translation:Animals
  102. Kohane DS, Kuang Y, Lu NT, Langer R, Strichartz GR, Berde CB. Vanilloid receptor agonists potentiate the in vivo local anesthetic activity of percutaneously injected site 1 sodium channel blockers. Anesthesiology. 1999 Feb; 90(2):524-34. PMID: 9952161.
    Citations: 3     Fields:    Translation:Animals
  103. Xiong Z, Bukusoglu C, Strichartz GR. Local anesthetics inhibit the G protein-mediated modulation of K+ and Ca++ currents in anterior pituitary cells. Mol Pharmacol. 1999 Jan; 55(1):150-8. PMID: 9882709.
    Citations: 4     Fields:    Translation:Animals
  104. Xiong Z, Strichartz GR. Inhibition by local anesthetics of Ca2+ channels in rat anterior pituitary cells. Eur J Pharmacol. 1998 Dec 11; 363(1):81-90. PMID: 9877085.
    Citations: 4     Fields:    Translation:AnimalsCells
  105. Chamberlain LJ, Yannas IV, Hsu HP, Strichartz G, Spector M. Collagen-GAG substrate enhances the quality of nerve regeneration through collagen tubes up to level of autograft. Exp Neurol. 1998 Dec; 154(2):315-29. PMID: 9878170.
    Citations: 27     Fields:    Translation:AnimalsCells
  106. Davar G, Hans G, Fareed MU, Sinnott C, Strichartz G. Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve. Neuroreport. 1998 Jul 13; 9(10):2279-83. PMID: 9694215.
    Citations: 38     Fields:    Translation:Animals
  107. Kohane DS, Yieh J, Lu NT, Langer R, Strichartz GR, Berde CB. A re-examination of tetrodotoxin for prolonged duration local anesthesia. Anesthesiology. 1998 Jul; 89(1):119-31. PMID: 9667302.
    Citations: 26     Fields:    Translation:Animals
  108. Lambert DH, Strichartz GR. Every problem is an opportunity, or one person's poison is another person's remedy. Reg Anesth Pain Med. 1998 Jan-Feb; 23(1):3-6. PMID: 9552770.
    Citations:    Fields:    Translation:Humans
  109. Huang JH, Thalhammer JG, Raymond SA, Strichartz GR. Susceptibility to lidocaine of impulses in different somatosensory afferent fibers of rat sciatic nerve. J Pharmacol Exp Ther. 1997 Aug; 282(2):802-11. PMID: 9262344.
    Citations: 8     Fields:    Translation:AnimalsCells
  110. Popitz-Bergez FA, Leeson S, Thalhammer JG, Strichartz GR. Intraneural lidocaine uptake compared with analgesic differences between pregnant and nonpregnant rats. Reg Anesth. 1997 Jul-Aug; 22(4):363-71. PMID: 9223204.
    Citations: 2     Fields:    Translation:Animals
  111. Vladimirov M, Thalhammer JG, Hunt N, Feldman HS, Strichartz G. Neurophysiologic actions and neurological consequences of veratridine on the rat sciatic nerve. Anesthesiology. 1997 Apr; 86(4):945-56. PMID: 9105239.
    Citations:    Fields:    Translation:Animals
  112. Choi RH, Birknes JK, Popitz-Bergez FA, Kissin I, Strichartz GR. Pharmacokinetic nature of tachyphylaxis to lidocaine: peripheral nerve blocks and infiltration anesthesia in rats. Life Sci. 1997; 61(12):PL 177-84. PMID: 9315513.
    Citations: 4     Fields:    Translation:Animals
  113. Lambert DH, Lambert LA, Strichartz GR. Radicular irritation after spinal anesthesia. Anesthesiology. 1996 Nov; 85(5):1216-7. PMID: 8967608.
    Citations:    Fields:    Translation:Humans
  114. Waikar SS, Thalhammer JG, Raymond SA, Huang JH, Chang DS, Strichartz GR. Mechanoreceptive afferents exhibit functionally-specific activity dependent changes in conduction velocity. Brain Res. 1996 May 20; 721(1-2):91-100. PMID: 8793088.
    Citations: 3     Fields:    Translation:AnimalsCells
  115. Strichartz G. Protracted relief of experimental neuropathic pain by systemic local anesthetics. How, where, and when. Anesthesiology. 1995 Oct; 83(4):654-5. PMID: 7574043.
    Citations:    Fields:    Translation:Animals
  116. Strichartz GR, Lambert DH. Neurotoxicity of 5% lignocaine. Br J Anaesth. 1995 Sep; 75(3):376. PMID: 7547073.
    Citations:    Fields:    Translation:Animals
  117. Popitz-Bergez FA, Leeson S, Strichartz GR, Thalhammer JG. Relation between functional deficit and intraneural local anesthetic during peripheral nerve block. A study in the rat sciatic nerve. Anesthesiology. 1995 Sep; 83(3):583-92. PMID: 7661359.
    Citations: 4     Fields:    Translation:Animals
  118. Strichartz GR, Hall S, Magnani B, Hong CY, Kishi Y, Debin JA. The potencies of synthetic analogues of saxitoxin and the absolute stereoselectivity of decarbamoyl saxitoxin. Toxicon. 1995 Jun; 33(6):723-37. PMID: 7676464.
    Citations: 4     Fields:    Translation:AnimalsCells
  119. Thalhammer JG, Vladimirova M, Bershadsky B, Strichartz GR. Neurologic evaluation of the rat during sciatic nerve block with lidocaine. Anesthesiology. 1995 Apr; 82(4):1013-25. PMID: 7717536.
    Citations: 45     Fields:    Translation:AnimalsCells
  120. McHugh J, Mok WM, Wang GK, Strichartz G. Irreversible inhibition of sodium current and batrachotoxin binding by a photoaffinity-derivatized local anesthetic. J Gen Physiol. 1995 Feb; 105(2):267-87. PMID: 7760019.
    Citations: 2     Fields:    Translation:AnimalsCells
  121. Li YM, Wingrove DE, Too HP, Marnerakis M, Stimson ER, Strichartz GR, Maggio JE. Local anesthetics inhibit substance P binding and evoked increases in intracellular Ca2+. Anesthesiology. 1995 Jan; 82(1):166-73. PMID: 7530414.
    Citations: 7     Fields:    Translation:AnimalsCells
  122. Desai S, Hadlock T, Messam C, Chafetz R, Strichartz G. Ionization and adsorption of a series of local anesthetics in detergent micelles: studies of drug fluorescence. J Pharmacol Exp Ther. 1994 Oct; 271(1):220-8. PMID: 7965718.
    Citations: 2     Fields:    Translation:Cells
  123. Bainton CR, Strichartz GR. Concentration dependence of lidocaine-induced irreversible conduction loss in frog nerve. Anesthesiology. 1994 Sep; 81(3):657-67. PMID: 8092513.
    Citations: 8     Fields:    Translation:Animals
  124. Wang ZY, Feng DM, Wang YL, Tung SR, Wong K, Strichartz GR, Folkers K, Håkanson R. Pharmacological assessment of spantide II analogues. Eur J Pharmacol. 1994 Aug 01; 260(2-3):121-8. PMID: 7527343.
    Citations: 1     Fields:    Translation:AnimalsCells
  125. DeBin JA, Wood MR, Pfenninger KH, Strichartz GR. A chloride channel reconstituted from fetal rat brain growth cones. J Membr Biol. 1994 Jul; 141(1):7-19. PMID: 7966248.
    Citations: 1     Fields:    Translation:AnimalsCells
  126. Shin HC, Park HJ, Raymond SA, Strichartz GR. Potentiation by capsaicin of lidocaine's tonic impulse block in isolated rat sciatic nerve. Neurosci Lett. 1994 Jun 06; 174(1):14-6. PMID: 7970146.
    Citations: 2     Fields:    Translation:AnimalsCells
  127. Lambert LA, Lambert DH, Strichartz GR. Irreversible conduction block in isolated nerve by high concentrations of local anesthetics. Anesthesiology. 1994 May; 80(5):1082-93. PMID: 8017646.
    Citations: 20     Fields:    Translation:Animals
  128. Wang ZY, Tung SR, Strichartz GR, Håkanson R. Investigation of the specificity of FK 888 as a tachykinin NK1 receptor antagonist. Br J Pharmacol. 1994 Apr; 111(4):1342-6. PMID: 7518299.
    Citations: 5     Fields:    Translation:Animals
  129. Wang ZY, Tung SR, Strichartz GR, Håkanson R. Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission. Br J Pharmacol. 1994 Jan; 111(1):179-84. PMID: 8012694.
    Citations: 10     Fields:    Translation:AnimalsCells
  130. Thalhammer JG, Raymond SA, Popitz-Bergez FA, Strichartz GR. Modality-dependent modulation of conduction by impulse activity in functionally characterized single cutaneous afferents in the rat. Somatosens Mot Res. 1994; 11(3):243-57. PMID: 7887056.
    Citations: 16     Fields:    Translation:AnimalsCells
  131. Wilder RT, Berde CB, Griggs CT, Chickalingaiah R, Strichartz G. Chronic exposure to lidocaine does not alter flux through sodium channels in cultured neuronal cells. Reg Anesth. 1993 Sep-Oct; 18(5):283-9. PMID: 8268116.
    Citations: 1     Fields:    Translation:AnimalsCells
  132. Chernoff DM, Strichartz GR, Piwnica-Worms D. Membrane potential determination in large unilamellar vesicles with hexakis(2-methoxyisobutylisonitrile)technetium(I). Biochim Biophys Acta. 1993 Apr 22; 1147(2):262-6. PMID: 8476920.
    Citations: 1     Fields:    
  133. DeBin JA, Maggio JE, Strichartz GR. Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion. Am J Physiol. 1993 Feb; 264(2 Pt 1):C361-9. PMID: 8383429.
    Citations: 56     Fields:    Translation:AnimalsCells
  134. Butterworth JF, Strichartz GR. The alpha 2-adrenergic agonists clonidine and guanfacine produce tonic and phasic block of conduction in rat sciatic nerve fibers. Anesth Analg. 1993 Feb; 76(2):295-301. PMID: 8093828.
    Citations: 27     Fields:    Translation:AnimalsCells
  135. Wong K, Strichartz GR, Raymond SA. On the mechanisms of potentiation of local anesthetics by bicarbonate buffer: drug structure-activity studies on isolated peripheral nerve. Anesth Analg. 1993 Jan; 76(1):131-43. PMID: 8418714.
    Citations: 6     Fields:    Translation:AnimalsCells
  136. Wood MR, DeBin J, Strichartz GR, Pfenninger KH. Plasmalemmal insertion and modification of sodium channels at the nerve growth cone. J Neurosci. 1992 Aug; 12(8):2948-59. PMID: 1322979.
    Citations: 3     Fields:    Translation:AnimalsCells
  137. Lee-Son S, Wang GK, Concus A, Crill E, Strichartz G. Stereoselective inhibition of neuronal sodium channels by local anesthetics. Evidence for two sites of action? Anesthesiology. 1992 Aug; 77(2):324-35. PMID: 1322642.
    Citations: 16     Fields:    Translation:Animals
  138. Raymond SA, Abrams SB, Raemer DB, Philip JH, Strichartz GR. The NerveSeeker: a system for automated nerve localization. Reg Anesth. 1992 May-Jun; 17(3):151-62. PMID: 1606098.
    Citations:    Fields:    Translation:Animals
  139. Drachman D, Strichartz G. Potassium channel blockers potentiate impulse inhibition by local anesthetics. Anesthesiology. 1991 Dec; 75(6):1051-61. PMID: 1741497.
    Citations: 4     Fields:    Translation:Animals
  140. Gold MR, Strichartz GR. Acute effects of repetitive depolarization on sodium current in chick myocytes. Am J Physiol. 1991 Jun; 260(6 Pt 2):H1810-8. PMID: 1647695.
    Citations:    Fields:    Translation:AnimalsCells
  141. Gold MR, Strichartz GR. Use-dependent block of atrial sodium current by ethylisopropylamiloride. J Cardiovasc Pharmacol. 1991 May; 17(5):792-9. PMID: 1713995.
    Citations: 4     Fields:    Translation:Animals
  142. Schneider M, Datta S, Strichartz G. A preferential inhibition of impulses in C-fibers of the rabbit vagus nerve by veratridine, an activator of sodium channels. Anesthesiology. 1991 Feb; 74(2):270-80. PMID: 1846725.
    Citations:    Fields:    Translation:AnimalsCells
  143. Guo XT, Castle NA, Chernoff DM, Strichartz GR. Comparative inhibition of voltage-gated cation channels by local anesthetics. Ann N Y Acad Sci. 1991; 625:181-99. PMID: 1647723.
    Citations: 7     Fields:    Translation:AnimalsCells
  144. DeBin JA, Strichartz GR. Chloride channel inhibition by the venom of the scorpion Leiurus quinquestriatus. Toxicon. 1991; 29(11):1403-8. PMID: 1726031.
    Citations: 18     Fields:    Translation:AnimalsCells
  145. Hahin R, Wang GK, Shapiro BI, Strichartz G. Alterations in sodium channel gating produced by the venom of the marine mollusc Conus striatus. Toxicon. 1991; 29(2):245-59. PMID: 1646501.
    Citations: 1     Fields:    Translation:AnimalsCells
  146. Raymond SA, Thalhammer JG, Popitz-Bergez F, Strichartz GR. Changes in axonal impulse conduction correlate with sensory modality in primary afferent fibers in the rat. Brain Res. 1990 Sep 03; 526(2):318-21. PMID: 2257488.
    Citations: 16     Fields:    Translation:AnimalsCells
  147. Strichartz GR, Sanchez V, Arthur GR, Chafetz R, Martin D. Fundamental properties of local anesthetics. II. Measured octanol:buffer partition coefficients and pKa values of clinically used drugs. Anesth Analg. 1990 Aug; 71(2):158-70. PMID: 2375517.
    Citations: 30     Fields:    Translation:Cells
  148. Chernoff DM, Strichartz GR. Kinetics of local anesthetic inhibition of neuronal sodium currents. pH and hydrophobicity dependence. Biophys J. 1990 Jul; 58(1):69-81. PMID: 2166602.
    Citations: 19     Fields:    Translation:AnimalsCells
  149. Butterworth JF, Strichartz GR. Molecular mechanisms of local anesthesia: a review. Anesthesiology. 1990 Apr; 72(4):711-34. PMID: 2157353.
    Citations: 103     Fields:    Translation:HumansAnimalsCells
  150. Raymond SA, Strichartz GR. Further comments on the failure of impulse propagation in nerves marginally blocked by local anesthetic. Anesth Analg. 1990 Jan; 70(1):121-2. PMID: 2297095.
    Citations:    Fields:    Translation:Humans
  151. Chernoff DM, Strichartz GR. Tonic and phasic block of neuronal sodium currents by 5-hydroxyhexano-2',6'-xylide, a neutral lidocaine homologue. J Gen Physiol. 1989 Jun; 93(6):1075-90. PMID: 2549174.
    Citations: 7     Fields:    Translation:AnimalsCells
  152. Raymond SA, Strichartz GR. The long and short of differential block. Anesthesiology. 1989 May; 70(5):725-8. PMID: 2719304.
    Citations:    Fields:    Translation:HumansCells
  153. Raymond SA, Steffensen SC, Gugino LD, Strichartz GR. The role of length of nerve exposed to local anesthetics in impulse blocking action. Anesth Analg. 1989 May; 68(5):563-70. PMID: 2785778.
    Citations: 12     Fields:    Translation:AnimalsCells
  154. Benzon HT, Strichartz GR, Gissen AJ, Shanks CA, Covino BG, Datta S. Developmental neurophysiology of mammalian peripheral nerves and age-related differential sensitivity to local anaesthetic. Br J Anaesth. 1988 Dec; 61(6):754-60. PMID: 3207547.
    Citations: 3     Fields:    Translation:AnimalsCells
  155. Strichartz GR. Through the eye of the channel: considerations of a reductionist view of general anesthesia. Anesthesiology. 1988 Aug; 69(2):155-6. PMID: 2457339.
    Citations:    Fields:    Translation:Humans
  156. Butterworth JF, Lief PA, Strichartz GR. The pH-dependent local anesthetic activity of diethylaminoethanol, a procaine metabolite. Anesthesiology. 1988 Apr; 68(4):501-6. PMID: 3258481.
    Citations:    Fields:    Translation:Animals
  157. Castle NA, Strichartz GR. Palytoxin induces a relatively non-selective cation permeability in frog sciatic nerve which can be inhibited by cardiac glycosides. Toxicon. 1988; 26(10):941-51. PMID: 2904712.
    Citations: 3     Fields:    Translation:Animals
  158. Butterworth JF, Moran JR, Whitesides GM, Strichartz GR. Limited nerve impulse blockade by "leashed" local anesthetics. J Med Chem. 1987 Aug; 30(8):1295-302. PMID: 2441052.
    Citations: 1     Fields:    Translation:AnimalsCells
  159. Benzon HT, Gissen AJ, Strichartz GR, Avram MJ, Covino BG. The effect of polyethylene glycol on mammalian nerve impulses. Anesth Analg. 1987 Jun; 66(6):553-9. PMID: 3578866.
    Citations: 7     Fields:    Translation:AnimalsCells
  160. Tamplin ML, Colwell RR, Hall S, Kogure K, Strichartz GR. Sodium-channel inhibitors produced by enteropathogenic Vibrio cholerae and Aeromonas hydrophila. Lancet. 1987 Apr 25; 1(8539):975. PMID: 2436014.
    Citations: 4     Fields:    Translation:AnimalsCells
  161. Wang GK, Brodwick MS, Eaton DC, Strichartz GR. Inhibition of sodium currents by local anesthetics in chloramine-T-treated squid axons. The role of channel activation. J Gen Physiol. 1987 Apr; 89(4):645-67. PMID: 2438374.
    Citations: 34     Fields:    Translation:AnimalsCells
  162. Sanchez V, Arthur GR, Strichartz GR. Fundamental properties of local anesthetics. I. The dependence of lidocaine's ionization and octanol:buffer partitioning on solvent and temperature. Anesth Analg. 1987 Feb; 66(2):159-65. PMID: 3813059.
    Citations: 15     Fields:    
  163. Chesnut TJ, Carpenter DO, Strichartz GR. Effects of venom from Conus striatus on the delayed rectifier potassium current of molluscan neurons. Toxicon. 1987; 25(3):267-78. PMID: 3590211.
    Citations: 1     Fields:    Translation:AnimalsCells
  164. Strichartz G, Rando T, Wang GK. An integrated view of the molecular toxinology of sodium channel gating in excitable cells. Annu Rev Neurosci. 1987; 10:237-67. PMID: 2436544.
    Citations: 38     Fields:    Translation:Animals
  165. Bokesch PM, Raymond SA, Strichartz GR. Dependence of lidocaine potency on pH and PCO2. Anesth Analg. 1987 Jan; 66(1):9-17. PMID: 3099602.
    Citations: 7     Fields:    Translation:AnimalsCells
  166. Strichartz GR, Wang GK. Rapid voltage-dependent dissociation of scorpion alpha-toxins coupled to Na channel inactivation in amphibian myelinated nerves. J Gen Physiol. 1986 Sep; 88(3):413-35. PMID: 2428923.
    Citations: 16     Fields:    Translation:AnimalsCells
  167. Moczydlowski E, Olivera BM, Gray WR, Strichartz GR. Discrimination of muscle and neuronal Na-channel subtypes by binding competition between [3H]saxitoxin and mu-conotoxins. Proc Natl Acad Sci U S A. 1986 Jul; 83(14):5321-5. PMID: 2425365.
    Citations: 42     Fields:    Translation:AnimalsCells
  168. Bokesch PM, Post C, Strichartz G. Structure-activity relationship of lidocaine homologs producing tonic and frequency-dependent impulse blockade in nerve. J Pharmacol Exp Ther. 1986 Jun; 237(3):773-81. PMID: 2423682.
    Citations: 13     Fields:    Translation:AnimalsCells
  169. Rando TA, Wang GK, Strichartz GR. The interaction between the activator agents batrachotoxin and veratridine and the gating processes of neuronal sodium channels. Mol Pharmacol. 1986 May; 29(5):467-77. PMID: 2422536.
    Citations: 7     Fields:    Translation:AnimalsCells
  170. Rando TA, Strichartz GR. Saxitoxin blocks batrachotoxin-modified sodium channels in the node of Ranvier in a voltage-dependent manner. Biophys J. 1986 Mar; 49(3):785-94. PMID: 2421797.
    Citations: 6     Fields:    Translation:AnimalsCells
  171. Strichartz G, Rando T, Hall S, Gitschier J, Hall L, Magnani B, Bay CH. On the mechanism by which saxitoxin binds to and blocks sodium channels. Ann N Y Acad Sci. 1986; 479:96-112. PMID: 2434011.
    Citations: 7     Fields:    Translation:AnimalsCells
  172. Post C, Butterworth JF, Strichartz GR, Karlsson JA, Persson CG. Tachykinin antagonists have potent local anaesthetic actions. Eur J Pharmacol. 1985 Nov 19; 117(3):347-54. PMID: 2416579.
    Citations: 12     Fields:    Translation:Animals
  173. Wang GK, Strichartz G. Kinetic analysis of the action of Leiurus scorpion alpha-toxin on ionic currents in myelinated nerve. J Gen Physiol. 1985 Nov; 86(5):739-62. PMID: 2415671.
    Citations: 17     Fields:    Translation:AnimalsCells
  174. Jackson FR, Gitschier J, Strichartz GR, Hall LM. Genetic modifications of voltage-sensitive sodium channels in Drosophila: gene dosage studies of the seizure locus. J Neurosci. 1985 May; 5(5):1144-51. PMID: 2582101.
    Citations: 8     Fields:    Translation:Animals
  175. Wildsmith JA, Strichartz GR. Local anaesthetic drugs--an historical perspective. Br J Anaesth. 1984 Sep; 56(9):937-9. PMID: 6380551.
    Citations: 2     Fields:    Translation:HumansAnimals
  176. Strichartz G. Structural determinants of the affinity of saxitoxin for neuronal sodium channels. Electrophysiological studies on frog peripheral nerve. J Gen Physiol. 1984 Aug; 84(2):281-305. PMID: 6092517.
    Citations: 17     Fields:    Translation:AnimalsCells
  177. Strichartz GR, Small RK, Pfenninger KH. Components of the plasma membrane of growing axons. III. Saxitoxin binding to sodium channels. J Cell Biol. 1984 Apr; 98(4):1444-52. PMID: 6325471.
    Citations: 6     Fields:    Translation:AnimalsCells
  178. Jackson FR, Wilson SD, Strichartz GR, Hall LM. Two types of mutants affecting voltage-sensitive sodium channels in Drosophila melanogaster. Nature. 1984 Mar 8-14; 308(5955):189-91. PMID: 6322008.
    Citations: 19     Fields:    Translation:AnimalsCells
  179. Dodt HU, Strichartz GR, Zimmermann M. Phenol solutions differentially block conduction in cutaneous nerve fibers of the cat. Neurosci Lett. 1983 Dec 11; 42(3):323-7. PMID: 6664635.
    Citations:    Fields:    Translation:AnimalsCells
  180. Strichartz G, Bar-Sagi D, Prives J. Differential expression of sodium channel activities during the development of chick skeletal muscle cells in culture. J Gen Physiol. 1983 Sep; 82(3):365-84. PMID: 6313850.
    Citations: 3     Fields:    Translation:AnimalsCells
  181. Wang GK, Strichartz GR. Purification and physiological characterization of neurotoxins from venoms of the scorpions centruroides sculpturatus and leiurus quinquestriatus. Mol Pharmacol. 1983 Mar; 23(2):519-33. PMID: 6300654.
    Citations: 19     Fields:    Translation:AnimalsCells
  182. Wang GK, Strichartz G. Simultaneous modifications of sodium channel gating by two scorpion toxins. Biophys J. 1982 Nov; 40(2):175-9. PMID: 6293596.
    Citations: 6     Fields:    Translation:Animals
  183. Strichartz G. Structure of the saxitoxin binding site at sodium channels in nerve membranes. Exchange of tritium from bound toxin molecules. Mol Pharmacol. 1982 Mar; 21(2):343-50. PMID: 6285170.
    Citations: 4     Fields:    Translation:AnimalsCells
  184. Cohen I, Attwell D, Strichartz G. The dependence of the maximum rate of rise of the action potential upstroke on membrane properties. Proc R Soc Lond B Biol Sci. 1981 Dec 09; 214(1194):85-98. PMID: 6121330.
    Citations: 12     Fields:    Translation:Cells
  185. Hahin R, Strichartz G. Effects of deuterium oxide on the rate and dissociation constants for saxitoxin and tetrodotoxin action. Voltage-clamp studies on frog myelinated nerve. J Gen Physiol. 1981 Aug; 78(2):113-39. PMID: 6268735.
    Citations: 12     Fields:    Translation:AnimalsCells
  186. Strichartz GR. Current concepts of the mechanism of action of local anesthetics. J Dent Res. 1981 Aug; 60(8):1460-70. PMID: 6265515.
    Citations: 3     Fields:    Translation:Cells
  187. Strichartz GR, Hanson Bay CM. Saxitoxin binding in nerves from walking legs of the lobster Homarus americanus. Two classes of receptors. J Gen Physiol. 1981 Feb; 77(2):205-21. PMID: 6267162.
    Citations: 2     Fields:    Translation:AnimalsCells
  188. Strichartz GR. Pharmacological properties of sodium channels in nerve membranes. Adv Neurol. 1981; 31:343-56. PMID: 6275671.
    Citations: 1     Fields:    Translation:AnimalsCells
  189. Strichartz G. Use-dependent conduction block produced by volatile general anesthetic agents. Acta Anaesthesiol Scand. 1980 Oct; 24(5):402-6. PMID: 6970493.
    Citations: 1     Fields:    Translation:Animals
  190. Strichartz GR, Oxford GS, Ramon F. Effects of the dipolar form of phloretin on potassium conductance in squid giant axons. Biophys J. 1980 Aug; 31(2):229-46. PMID: 6266534.
    Citations: 9     Fields:    Translation:AnimalsCells
  191. Bay CM, Strichartz GR. Saxitoxin binding to sodium channels of rat skeletal muscles. J Physiol. 1980 Mar; 300:89-103. PMID: 6247488.
    Citations: 19     Fields:    Translation:AnimalsCells
  192. Gitschier J, Strichartz GR, Hall LM. Saxitoxin binding to sodium channels in head extracts from wild-type and tetrodotoxin-sensitive strains of Drosophila melanogaster. Biochim Biophys Acta. 1980 Jan 25; 595(2):291-303. PMID: 6766315.
    Citations: 5     Fields:    Translation:AnimalsCells
  193. Krueger BK, Ratzlaff RW, Strichartz GR, Blaustein MP. Saxitoxin binding to synaptosomes, membranes, and solubilized binding sites from rat brain. J Membr Biol. 1979 Nov 30; 50(3-4):287-310. PMID: 513116.
    Citations: 35     Fields:    Translation:AnimalsCells
  194. Tang CM, Strichartz GR, Orkand RK. Sodium channels in axons and glial cells of the optic nerve of Necturus maculosa. J Gen Physiol. 1979 Nov; 74(5):629-42. PMID: 512633.
    Citations: 9     Fields:    Translation:AnimalsCells
  195. Strichartz GR, Rogart RB, Ritchie JM. Binding of radioactively labeled saxitoxin to the squid giant axon. J Membr Biol. 1979 Aug; 48(4):357-64. PMID: 490630.
    Citations: 7     Fields:    Translation:AnimalsCells
  196. Strichartz GR, Chiu SY, Ritchie JM. The effect of delta9-tetrahydrocannabinol on the activation of sodium conductance in node of Ranvier. J Pharmacol Exp Ther. 1978 Dec; 207(3):801-9. PMID: 310454.
    Citations:    Fields:    Translation:AnimalsCells
  197. Strichartz G, Cohen I. Vmax as a measure of GNa in nerve and cardiac membranes. Biophys J. 1978 Jul; 23(1):153-6. PMID: 667304.
    Citations: 15     Fields:    
  198. Strichartz G. Effects of tertiary local anesthetics and their quaternary derivatives on sodium channels of nerve membranes [proceedings]. Biophys J. 1977 Jun; 18(3):353-4. PMID: 890031.
    Citations: 1     Fields:    Translation:AnimalsCells
  199. Cohen IS, Strichartz GR. On the voltage-dependent action of tetrodotoxin. Biophys J. 1977 Mar; 17(3):275-9. PMID: 843585.
    Citations: 19     Fields:    Translation:AnimalsCells
  200. Ritchie JM, Rogart RB, Strichartz GR. A new method for labelling saxitoxin and its binding to non-myelinated fibres of the rabbit vagus, lobster walking leg, and garfish olfactory nerves. J Physiol. 1976 Oct; 261(2):477-94. PMID: 978583.