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Dan Gabriel Fraenkel, Ph.D.

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  1. R01GM021098 (FRAENKEL, DAN G) Aug 1, 1977 - Jul 31, 1994
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Fraenkel D, Nielsen J. Trehalose-6-phosphate synthase and stabilization of yeast glycolysis. FEMS Yeast Res. 2016 Feb; 16(1):fov100. PMID: 26564983.
    Citations: 1     Fields:    Translation:AnimalsCells
  2. Fraenkel DG. The top genes: on the distance from transcript to function in yeast glycolysis. Curr Opin Microbiol. 2003 Apr; 6(2):198-201. PMID: 12732312.
    Citations: 16     Fields:    Translation:AnimalsCells
  3. Heidrich K, Fraenkel DG. Setting of graded levels of a protein in yeast by a t-degron technique as applied to phosphoglycerate mutase. BMC Genet. 2002 Jul 30; 3:13. PMID: 12149134; PMCID: PMC117797.
    Citations:    Fields:    Translation:Animals
  4. Uemura H, Fraenkel DG. Glucose metabolism in gcr mutants of Saccharomyces cerevisiae. J Bacteriol. 1999 Aug; 181(15):4719-23. PMID: 10419980; PMCID: PMC103613.
    Citations: 8     Fields:    Translation:AnimalsCells
  5. Benevolensky SV, Clifton D, Fraenkel DG. The effect of increased phosphoglucose isomerase on glucose metabolism in Saccharomyces cerevisiae. J Biol Chem. 1994 Feb 18; 269(7):4878-82. PMID: 8106459.
    Citations: 7     Fields:    Translation:Animals
  6. Kriegel TM, Rush J, Vojtek AB, Clifton D, Fraenkel DG. In vivo phosphorylation site of hexokinase 2 in Saccharomyces cerevisiae. Biochemistry. 1994 Jan 11; 33(1):148-52. PMID: 8286332.
    Citations: 24     Fields:    Translation:AnimalsCells
  7. Clifton D, Walsh RB, Fraenkel DG. Functional studies of yeast glucokinase. J Bacteriol. 1993 Jun; 175(11):3289-94. PMID: 8501032; PMCID: PMC204725.
    Citations: 11     Fields:    Translation:AnimalsCells
  8. Babul J, Clifton D, Kretschmer M, Fraenkel DG. Glucose metabolism in Escherichia coli and the effect of increased amount of aldolase. Biochemistry. 1993 May 04; 32(17):4685-92. PMID: 8485146.
    Citations: 7     Fields:    Translation:Cells
  9. Fraenkel DG. Genetics and intermediary metabolism. Annu Rev Genet. 1992; 26:159-77. PMID: 1482110.
    Citations: 14     Fields:    Translation:AnimalsCells
  10. Kretschmer M, Fraenkel DG. Yeast 6-phosphofructo-2-kinase: sequence and mutant. Biochemistry. 1991 Nov 05; 30(44):10663-72. PMID: 1657152.
    Citations: 12     Fields:    Translation:AnimalsCells
  11. Walsh RB, Clifton D, Horak J, Fraenkel DG. Saccharomyces cerevisiae null mutants in glucose phosphorylation: metabolism and invertase expression. Genetics. 1991 Jul; 128(3):521-7. PMID: 1874414.
    Citations: 17     Fields:    Translation:AnimalsCells
  12. Kretschmer M, Tempst P, Fraenkel DG. Identification and cloning of yeast phosphofructokinase 2. Eur J Biochem. 1991 Apr 23; 197(2):367-72. PMID: 1851090.
    Citations: 1     Fields:    Translation:AnimalsCells
  13. Uemura H, Fraenkel DG. gcr2, a new mutation affecting glycolytic gene expression in Saccharomyces cerevisiae. Mol Cell Biol. 1990 Dec; 10(12):6389-96. PMID: 2247062.
    Citations: 34     Fields:    Translation:AnimalsCells
  14. Vojtek AB, Fraenkel DG. Phosphorylation of yeast hexokinases. Eur J Biochem. 1990 Jun 20; 190(2):371-5. PMID: 2163841.
    Citations: 19     Fields:    Translation:AnimalsCells
  15. Babul J, Fraenkel DG. Phosphate modification of fructose-1,6-bisphosphate aldolase in Escherichia coli. Biochem Biophys Res Commun. 1988 Mar 30; 151(3):1033-8. PMID: 3281666.
    Citations: 1     Fields:    Translation:Cells
  16. Bisson LF, Neigeborn L, Carlson M, Fraenkel DG. The SNF3 gene is required for high-affinity glucose transport in Saccharomyces cerevisiae. J Bacteriol. 1987 Apr; 169(4):1656-62. PMID: 3549699; PMCID: PMC211996.
    Citations: 54     Fields:    Translation:Animals
  17. Sedivy JM, Babul J, Fraenkel DG. AMP-insensitive fructose bisphosphatase in Escherichia coli and its consequences. Proc Natl Acad Sci U S A. 1986 Mar; 83(6):1656-9. PMID: 3006063; PMCID: PMC323142.
    Citations: 5     Fields:    Translation:Cells
  18. Fraenkel DG. Mutants in glucose metabolism. Annu Rev Biochem. 1986; 55:317-37. PMID: 3017192.
    Citations: 20     Fields:    Translation:AnimalsCells
  19. Sedivy JM, Fraenkel DG. Fructose bisphosphatase of Saccharomyces cerevisiae. Cloning, disruption and regulation of the FBP1 structural gene. J Mol Biol. 1985 Nov 20; 186(2):307-19. PMID: 3003364.
    Citations: 23     Fields:    Translation:AnimalsCells
  20. Fraenkel DG. On ras gene function in yeast. Proc Natl Acad Sci U S A. 1985 Jul; 82(14):4740-4. PMID: 3895224; PMCID: PMC390980.
    Citations: 31     Fields:    Translation:Animals
  21. Bisson LF, Fraenkel DG. Expression of kinase-dependent glucose uptake in Saccharomyces cerevisiae. J Bacteriol. 1984 Sep; 159(3):1013-7. PMID: 6384176.
    Citations: 47     Fields:    Translation:AnimalsCells
  22. Sedivy JM, Daldal F, Fraenkel DG. Fructose bisphosphatase of Escherichia coli: cloning of the structural gene (fbp) and preparation of a chromosomal deletion. J Bacteriol. 1984 Jun; 158(3):1048-53. PMID: 6327623.
    Citations: 26     Fields:    Translation:Cells
  23. Bisson LF, Fraenkel DG. Transport of 6-deoxyglucose in Saccharomyces cerevisiae. J Bacteriol. 1983 Sep; 155(3):995-1000. PMID: 6350275.
    Citations: 24     Fields:    Translation:Animals
  24. Clifton D, Fraenkel DG. Fructose 2,6-bisphosphate and fructose-6-P 2-kinase in Saccharomyces cerevisiae in relation to metabolic state in wild type and fructose-6-P 1-kinase mutant strains. J Biol Chem. 1983 Aug 10; 258(15):9245-9. PMID: 6307998.
    Citations:    Fields:    Translation:AnimalsCells
  25. Walsh RB, Kawasaki G, Fraenkel DG. Cloning of genes that complement yeast hexokinase and glucokinase mutants. J Bacteriol. 1983 May; 154(2):1002-4. PMID: 6341351.
    Citations: 15     Fields:    Translation:Animals
  26. Bisson LF, Fraenkel DG. Involvement of kinases in glucose and fructose uptake by Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1983 Mar; 80(6):1730-4. PMID: 6300872; PMCID: PMC393677.
    Citations: 98     Fields:    Translation:Animals
  27. Daldal F, Fraenkel DG. Assessment of a futile cycle involving reconversion of fructose 6-phosphate to fructose 1,6-bisphosphate during gluconeogenic growth of Escherichia coli. J Bacteriol. 1983 Jan; 153(1):390-4. PMID: 6217196.
    Citations: 12     Fields:    Translation:Cells
  28. Kawasaki G, Fraenkel DG. Cloning of yeast glycolysis genes by complementation. Biochem Biophys Res Commun. 1982 Oct 15; 108(3):1107-22. PMID: 6295367.
    Citations: 32     Fields:    Translation:AnimalsCells
  29. Daldal F, Babul J, Guixé V, Fraenkel DG. An alteration in phosphofructokinase 2 of Escherichia coli which impairs gluconeogenic growth and improves growth on sugars. Eur J Biochem. 1982 Aug; 126(2):373-9. PMID: 6215246.
    Citations: 7     Fields:    Translation:Cells
  30. Bañuelos M, Fraenkel DG. Saccharomyces carlsbergensis fdp mutant and futile cycling of fructose 6-phosphate. Mol Cell Biol. 1982 Aug; 2(8):921-9. PMID: 6290872.
    Citations: 9     Fields:    Translation:AnimalsCells
  31. Clifton D, Fraenkel DG. Mutant studies of yeast phosphofructokinase. Biochemistry. 1982 Apr 13; 21(8):1935-42. PMID: 6211191.
    Citations: 10     Fields:    Translation:Animals
  32. Clifton D, Fraenkel DG. The gcr (glycolysis regulation) mutation of Saccharomyces cerevisiae. J Biol Chem. 1981 Dec 25; 256(24):13074-8. PMID: 7031056.
    Citations: 60     Fields:    Translation:AnimalsCells
  33. Daldal F, Fraenkel DG. Tn10 insertions in the pfkB region of Escherichia coli. J Bacteriol. 1981 Sep; 147(3):935-43. PMID: 6268614.
    Citations: 10     Fields:    Translation:Cells
  34. Fraenkel DG. The biochemical genetics of glycolysis in microbes. Basic Life Sci. 1981; 18:201-15. PMID: 7023458.
    Citations: 4     Fields:    Translation:AnimalsCells
  35. Chambost JP, Fraenkel DG. The use of 6-labeled glucose to assess futile cycling in Escherichia coli. J Biol Chem. 1980 Apr 10; 255(7):2867-9. PMID: 6244298.
    Citations: 12     Fields:    Translation:Cells
  36. de Silva AO, Fraenkel DG. The 6-phosphogluconate dehydrogenase reaction in Escherichia coli. J Biol Chem. 1979 Oct 25; 254(20):10237-42. PMID: 385598.
    Citations: 13     Fields:    Translation:Cells
  37. Duncan MJ, Fraenkel DG. alpha-Ketoglutarate dehydrogenase mutant of Rhizobium meliloti. J Bacteriol. 1979 Jan; 137(1):415-9. PMID: 762018.
    Citations: 46     Fields:    Translation:Cells
  38. Thomson J, Gerstenberger PD, Goldberg DE, Gociar E, Orozco de Silva A, Fraenkel DG. ColE1 hybrid plasmids for Escherichia coli genes of glycolysis and the hexose monophosphate shunt. J Bacteriol. 1979 Jan; 137(1):502-6. PMID: 368027.
    Citations: 25     Fields:    Translation:Cells
  39. Robinson JP, Fraenkel DG. Allosteric and non-allosteric E. coli phosphofructokinases: effects on growth. Biochem Biophys Res Commun. 1978 Apr 14; 81(3):858-63. PMID: 149541.
    Citations: 3     Fields:    Translation:Cells
  40. Clifton D, Weinstock SB, Fraenkel DG. Glycolysis mutants in Saccharomyces cerevisiae. Genetics. 1978 Jan; 88(1):1-11. PMID: 147195.
    Citations: 80     Fields:    Translation:AnimalsCells
  41. Gancedo JM, Clifton D, Fraenkel DG. Yeast hexokinase mutants. J Biol Chem. 1977 Jul 10; 252(13):4443-4. PMID: 326775.
    Citations: 30     Fields:    Translation:Animals
  42. Csonka LN, Fraenkel DG. Pathways of NADPH formation in Escherichia coli. J Biol Chem. 1977 May 25; 252(10):3382-91. PMID: 16899.
    Citations: 19     Fields:    Translation:Cells
  43. Babul J, Robinson JP, Fraenkel DG. Are the aerobic and anaerobic phosphofructokinases of Escherichia coli different? Eur J Biochem. 1977 Apr 15; 74(3):533-7. PMID: 140050.
    Citations: 2     Fields:    Translation:Cells
  44. Vinopal RT, Clifton D, Fraenkel DG. PfkA locus of Escherichia coli. J Bacteriol. 1975 Jun; 122(3):1162-71. PMID: 125265.
    Citations: 9     Fields:    Translation:Cells
  45. Hillman JD, Fraenkel DG. Glyceraldehyde 3-phosphate dehydrogenase mutants of Escherichia coli. J Bacteriol. 1975 Jun; 122(3):1175-9. PMID: 1097392.
    Citations: 36     Fields:    Translation:Cells
  46. Vinopal RT, Fraenkel DG. PfkB and pfkC loci of Escherichia coli. J Bacteriol. 1975 Jun; 122(3):1153-61. PMID: 125264.
    Citations: 13     Fields:    Translation:Cells
  47. Vinopal RT, Hillman JD, Schulman H, Reznikoff WS, Fraenkel DG. New phosphoglucose isomerase mutants of Escherichia coli. J Bacteriol. 1975 Jun; 122(3):1172-4. PMID: 1097391.
    Citations: 19     Fields:    Translation:Cells
  48. Vinopal RT, Fraenkel DG. Phenotypic suppression of phosphofructokinase mutations in Escherichia coli by constitutive expression of the glyoxylate shunt. J Bacteriol. 1974 Jun; 118(3):1090-100. PMID: 4275310.
    Citations: 21     Fields:    Translation:Cells
  49. Josephson BL, Fraenkel DG. Sugar metabolism in transketolase mutants of Escherichia coli. J Bacteriol. 1974 Jun; 118(3):1082-9. PMID: 4597996.
    Citations: 14     Fields:    Translation:Cells
  50. Wolf RE, Fraenkel DG. Isolation of specialized transducing bacteriophages for gluconate 6-phosphate dehydrogenase (gnd) of Escherichia coli. J Bacteriol. 1974 Feb; 117(2):468-76. PMID: 4590471.
    Citations: 13     Fields:    Translation:Cells
  51. Fraenkel DG, Kotlarz D, Buc H. Two fructose 6-phosphate kinase activities in Escherichia coli. J Biol Chem. 1973 Jul 10; 248(13):4865-6. PMID: 4268865.
    Citations: 13     Fields:    Translation:Cells
  52. Fraenkel DG, Parola A. "Up-promoter" mutations of glucose 6-phosphate dehydrogenase in Escherichia coli. J Mol Biol. 1972 Oct 28; 71(1):107-11. PMID: 4564298.
    Citations: 7     Fields:    Translation:Cells
  53. Morrissey AT, Fraenkel DG. Suppressor of phosphofructokinase mutations of Escherichia coli. J Bacteriol. 1972 Oct; 112(1):183-7. PMID: 4263401.
    Citations: 10     Fields:    Translation:Cells
  54. Fraenkel DG, Banerjee S. Deletion mapping of zwf, the gene for a constitutive enzyme, glucose 6-phosphate dehydrogenase in Escherichia coli. Genetics. 1972 Aug; 71(4):481-9. PMID: 4560065.
    Citations: 14     Fields:    Translation:Cells
  55. Banerjee S, Fraenkel DG. Glucose-6-phosphate dehydrogenase from Escherichia coli and from a "high-level" mutant. J Bacteriol. 1972 Apr; 110(1):155-60. PMID: 4401601.
    Citations: 17     Fields:    Translation:Cells
  56. Kupor SR, Fraenkel DG. Glucose metabolism in 6 phosphogluconolactonase mutants of Escherichia coli. J Biol Chem. 1972 Mar 25; 247(6):1904-10. PMID: 4552019.
    Citations: 13     Fields:    Translation:Cells
  57. Fradkin JE, Fraenkel DG. 2-keto-3-deoxygluconate 6-phosphate aldolase mutants of Escherichia coli. J Bacteriol. 1971 Dec; 108(3):1277-83. PMID: 4945194.
    Citations: 34     Fields:    Translation:Cells
  58. Fraenkel DG, Banerjee S. A mutation increasing the amount of a constitutive enzyme in Escherichia coli, glucose 6-phosphate dehydrogenase. J Mol Biol. 1971 Feb 28; 56(1):183-94. PMID: 4929885.
    Citations: 20     Fields:    Translation:AnimalsCells
  59. Kupor SR, Fraenkel DG. 6-phosphogluconolactonase mutants of Escherichia coli and a maltose blue gene. J Bacteriol. 1969 Dec; 100(3):1296-301. PMID: 4902810.
    Citations: 28     Fields:    Translation:Cells
  60. Josephson BL, Fraenkel DG. Transketolase mutants of Escherichia coli. J Bacteriol. 1969 Dec; 100(3):1289-95. PMID: 4902809.
    Citations: 37     Fields:    Translation:Cells
  61. Morrissey AT, Fraenkel DG. Chromosomal location of a gene for fructose 6-phosphate kinase in Escherichia coli. J Bacteriol. 1969 Nov; 100(2):1108-9. PMID: 4902384.
    Citations: 9     Fields:    Translation:Cells
  62. Fraenkel DG. The accumulation of glucose 6-phosphate from glucose and its effect in an Escherichia coli mutant lacking phosphoglucose isomerase and glucose 6-phosphate dehydrogenase. J Biol Chem. 1968 Dec 25; 243(24):6451-7. PMID: 4302393.
    Citations: 48     Fields:    Translation:Cells
  63. Fraenkel DG. The phosphoenolpyruvate-initiated pathway of fructose metabolism in Escherichia coli. J Biol Chem. 1968 Dec 25; 243(24):6458-63. PMID: 4882209.
    Citations: 27     Fields:    Translation:Cells
  64. Morrissey AT, Fraenkel DG. Selection of fructose 6-phosphate kinase mutants in Escherichia coli. Biochem Biophys Res Commun. 1968 Aug 13; 32(3):467-73. PMID: 4299078.
    Citations: 9     Fields:    Translation:Cells
  65. Fraenkel DG. Selection of Escherichia coli mutants lacking glucose-6-phosphate dehydrogenase or gluconate-6-phosphate dehydrogenase. J Bacteriol. 1968 Apr; 95(4):1267-71. PMID: 4869212.
    Citations: 48     Fields:    Translation:Cells
  66. Peyru G, Fraenkel DG. Genetic mapping of loci for glucose-6-phosphate dehydrogenase, gluconate-6-phosphate dehydrogenase, and gluconate-6-phosphate dehydrase in Escherichia coli. J Bacteriol. 1968 Apr; 95(4):1272-8. PMID: 4869213.
    Citations: 27     Fields:    Translation:Cells
  67. Fraenkel DG. Genetic mapping of mutations affecting phosphoglucose isomerase and fructose diphosphatase in Escherichia coli. J Bacteriol. 1967 May; 93(5):1582-7. PMID: 4290578.
    Citations: 34     Fields:    Translation:Cells
  68. Zablotny R, Fraenkel DG. Glucose and gluconate metabolism in a mutant of Escherichia coli lacking gluconate-6-phosphate dehydrase. J Bacteriol. 1967 May; 93(5):1579-81. PMID: 5337844.
    Citations: 29     Fields:    Translation:Cells
  69. Fraenkel DG, Levisohn SR. Glucose and gluconate metabolism in an Escherichia coli mutant lacking phosphoglucose isomerase. J Bacteriol. 1967 May; 93(5):1571-8. PMID: 5337843.
    Citations: 80     Fields:    Translation:Cells
  70. Tanaka S, Fraenkel DG, Lin EC. The enzymatic lesion of strain MM-6, a pleiotropic carbohydrate-negative mutant of Escherichia coli. Biochem Biophys Res Commun. 1967 Apr 07; 27(1):63-7. PMID: 4862174.
    Citations: 38     Fields:    Translation:Cells
  71. Fraenkel DG, Pontremoli S, Horecker BL. The specific fructose diphosphatase of Escherichia coli: properties and partial purification. Arch Biochem Biophys. 1966 Apr; 114(1):4-12. PMID: 4289037.
    Citations: 12     Fields:    Translation:Cells
  72. Fraenkel DG, Horecker BL. Fructose-1, 6-diphosphatase and acid hexose phosphatase of Escherichia coli. J Bacteriol. 1965 Oct; 90(4):837-42. PMID: 4284917.
    Citations: 38     Fields:    Translation:Cells
    Citations: 36     Fields:    Translation:Cells
    Citations: 48     Fields:    Translation:Cells
  75. FRAENKEL D, OSBORN MJ, HORECKER BL, SMITH SM. Metabolism and cell wall structure of a mutant of Salmonella typhimurium deficient in phosphoglucose isomerase. Biochem Biophys Res Commun. 1963 Jun 20; 11:423-8. PMID: 13959084.
    Citations: 21     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.