Harvard Catalyst Profiles

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Shaomin Li, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Li S, Stern AM. Bioactive human Alzheimer brain soluble Aß: pathophysiology and therapeutic opportunities. Mol Psychiatry. 2022 08; 27(8):3182-3191. PMID: 35484241.
    Citations: 3     Fields:    Translation:Humans
  2. Li S, Jin M, Liu L, Dang Y, Ostaszewski BL, Selkoe DJ. Decoding the synaptic dysfunction of bioactive human AD brain soluble Aß to inspire novel therapeutic avenues for Alzheimer's disease. Acta Neuropathol Commun. 2018 11 08; 6(1):121. PMID: 30409172.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  3. Li S, Jin M, Zhang D, Yang T, Koeglsperger T, Fu H, Selkoe DJ. Environmental novelty activates ß2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aß oligomers. Neuron. 2013 Mar 06; 77(5):929-41. PMID: 23473322.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  4. Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar GM, Selkoe DJ. Soluble Aß oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors. J Neurosci. 2011 May 04; 31(18):6627-38. PMID: 21543591.
    Citations: 308     Fields:    Translation:AnimalsCells
  5. Li S, Shankar GM, Selkoe DJ. How do Soluble Oligomers of Amyloid beta-protein Impair Hippocampal Synaptic Plasticity? Front Cell Neurosci. 2010; 4:5. PMID: 20428510.
    Citations: 17     
  6. Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron. 2009 Jun 25; 62(6):788-801. PMID: 19555648.
    Citations: 444     Fields:    Translation:HumansAnimalsCells
  7. Arai JA, Li S, Hartley DM, Feig LA. Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment. J Neurosci. 2009 Feb 04; 29(5):1496-502. PMID: 19193896.
    Citations: 59     Fields:    Translation:Animals
  8. Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med. 2008 Aug; 14(8):837-42. PMID: 18568035.
    Citations: 1705     Fields:    Translation:HumansAnimalsCells
  9. Li S, Feig LA, Hartley DM. A brief, but repeated, swimming protocol is sufficient to overcome amyloid beta-protein inhibition of hippocampal long-term potentiation. Eur J Neurosci. 2007 Sep; 26(5):1289-98. PMID: 17767506.
    Citations: 4     Fields:    Translation:Animals
  10. Li S, Topchiy I, Kocsis B. The effect of atropine administered in the medial septum or hippocampus on high- and low-frequency theta rhythms in the hippocampus of urethane anesthetized rats. Synapse. 2007 Jun; 61(6):412-9. PMID: 17372965.
    Citations: 15     Fields:    Translation:AnimalsCells
  11. Kocsis B, Li S, Hajos M. Behavior-dependent modulation of hippocampal EEG activity by the selective norepinephrine reuptake inhibitor reboxetine in rats. Hippocampus. 2007; 17(8):627-33. PMID: 17492692.
    Citations: 11     Fields:    Translation:Animals
  12. Li S, Tian X, Hartley DM, Feig LA. The environment versus genetics in controlling the contribution of MAP kinases to synaptic plasticity. Curr Biol. 2006 Dec 05; 16(23):2303-13. PMID: 17141611.
    Citations: 24     Fields:    Translation:AnimalsCells
  13. Li S, Tian X, Hartley DM, Feig LA. Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression. J Neurosci. 2006 Feb 08; 26(6):1721-9. PMID: 16467520; PMCID: PMC6793631.
    Citations: 79     Fields:    Translation:AnimalsCells
  14. Li S, Varga V, Sik A, Kocsis B. GABAergic control of the ascending input from the median raphe nucleus to the limbic system. J Neurophysiol. 2005 Oct; 94(4):2561-74. PMID: 15944232; PMCID: PMC1224729.
    Citations: 8     Fields:    Translation:Animals
  15. Kocsis B, Li S. In vivo contribution of h-channels in the septal pacemaker to theta rhythm generation. Eur J Neurosci. 2004 Oct; 20(8):2149-58. PMID: 15450094.
    Citations: 28     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.