Keith Wyatt Miller, Dr.Phil.
This page shows the publications co-authored by Keith Miller and Selwyn Jayakar.
Jayakar SS, Chiara DC, Zhou X, Wu B, Bruzik KS, Miller KW, Cohen JB. Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABAA) receptors. J Biol Chem. 2020 Aug 14; 295(33):11495-11512.
Jayakar SS, Zhou X, Chiara DC, Jarava-Barrera C, Savechenkov PY, Bruzik KS, Tortosa M, Miller KW, Cohen JB. Identifying Drugs that Bind Selectively to Intersubunit General Anesthetic Sites in the a1ß3?2 GABAAR Transmembrane Domain. Mol Pharmacol. 2019 06; 95(6):615-628.
Jayakar SS, Zhou X, Savechenkov PY, Chiara DC, Desai R, Bruzik KS, Miller KW, Cohen JB. Positive and Negative Allosteric Modulation of an a1ß3?2 ?-Aminobutyric Acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the ?+-ß- Interface. J Biol Chem. 2015 Sep 18; 290(38):23432-46.
Jayakar SS, Zhou X, Chiara DC, Dostalova Z, Savechenkov PY, Bruzik KS, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Multiple propofol-binding sites in a ?-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog. J Biol Chem. 2014 Oct 03; 289(40):27456-68.
McGrath M, Hoyt H, Pence A, Jayakar SS, Zhou X, Forman SA, Cohen JB, Miller KW, Raines DE. Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology. 2020 09; 133(3):583-594.
Wu B, Jayakar SS, Zhou X, Titterton K, Chiara DC, Szabo AL, Savechenkov PY, Kent DE, Cohen JB, Forman SA, Miller KW, Bruzik KS. Inhibitable photolabeling by neurosteroid diazirine analog in the ß3-Subunit of human hetereopentameric type A GABA receptors. Eur J Med Chem. 2019 Jan 15; 162:810-824.
McGrath M, Yu Z, Jayakar SS, Ma C, Tolia M, Zhou X, Miller KW, Cohen JB, Raines DE. Etomidate and Etomidate Analog Binding and Positive Modulation of ?-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. Anesthesiology. 2018 11; 129(5):959-969.
Ma C, Pejo E, McGrath M, Jayakar SS, Zhou X, Miller KW, Cohen JB, Raines DE. Competitive Antagonism of Anesthetic Action at the ?-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy. Anesthesiology. 2017 11; 127(5):824-837.
Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human a1ß3?2 ?-aminobutyric acid type A (GABAA) receptor. J Biol Chem. 2013 Jul 05; 288(27):19343-57.
Chiara DC, Dostalova Z, Jayakar SS, Zhou X, Miller KW, Cohen JB. Mapping general anesthetic binding site(s) in human a1ß3 ?-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue. Biochemistry. 2012 Jan 31; 51(4):836-47.
The connection strength for co-authors is the sum of the scores for each of their shared publications.
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