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Jean C. Augustinack, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AG057672 (AUGUSTINACK, JEAN) Aug 15, 2018 - Apr 30, 2023
    NIH/NIA
    Building a pathology-validated neuroimaging tool for Alzheimer's Disease
    Role: Principal Investigator
  2. K01AG028521 (AUGUSTINACK, JEAN) Aug 1, 2008 - Sep 30, 2013
    NIH/NIA
    Magnetic Resonance Microscopy of Alzheimers Disease Pathology
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Aganj I, Frau-Pascual A, Iglesias JE, Yendiki A, Augustinack JC, Salat DH, Fischl B. COMPENSATORY BRAIN CONNECTION DISCOVERY IN ALZHEIMER'S DISEASE. Proc IEEE Int Symp Biomed Imaging. 2020 Apr; 2020:283-287. PMID: 32587665.
    Citations:    
  2. Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. The presubiculum links incipient amyloid and tau pathology to memory function in older persons. Neurology. 2020 May 05; 94(18):e1916-e1928. PMID: 32273431.
    Citations:    
  3. Jones R, Grisot G, Augustinack J, Magnain C, Boas DA, Fischl B, Wang H, Yendiki A. Insight into the fundamental trade-offs of diffusion MRI from polarization-sensitive optical coherence tomography in ex vivo human brain. Neuroimage. 2020 Jul 01; 214:116704. PMID: 32151760.
    Citations:    
  4. Singh K, Indovina I, Augustinack JC, Nestor K, García-Gomar MG, Staab JP, Bianciardi M. Probabilistic Template of the Lateral Parabrachial Nucleus, Medial Parabrachial Nucleus, Vestibular Nuclei Complex, and Medullary Viscero-Sensory-Motor Nuclei Complex in Living Humans From 7 Tesla MRI. Front Neurosci. 2019; 13:1425. PMID: 32038134.
    Citations:    
  5. Edlow BL, Mareyam A, Horn A, Polimeni JR, Witzel T, Tisdall MD, Augustinack JC, Stockmann JP, Diamond BR, Stevens A, Tirrell LS, Folkerth RD, Wald LL, Fischl B, van der Kouwe A. 7 Tesla MRI of the ex vivo human brain at 100 micron resolution. Sci Data. 2019 10 30; 6(1):244. PMID: 31666530.
    Citations:    
  6. Olsen RK, Carr VA, Daugherty AM, La Joie R, Amaral RSC, Amunts K, Augustinack JC, Bakker A, Bender AR, Berron D, Boccardi M, Bocchetta M, Burggren AC, Chakravarty MM, Chételat G, de Flores R, DeKraker J, Ding SL, Geerlings MI, Huang Y, Insausti R, Johnson EG, Kanel P, Kedo O, Kennedy KM, Keresztes A, Lee JK, Lindenberger U, Mueller SG, Mulligan EM, Ofen N, Palombo DJ, Pasquini L, Pluta J, Raz N, Rodrigue KM, Schlichting ML, Lee Shing Y, Stark CEL, Steve TA, Suthana NA, Wang L, Werkle-Bergner M, Yushkevich PA, Yu Q, Wisse LEM. Progress update from the hippocampal subfields group. Alzheimers Dement (Amst). 2019 Dec; 11:439-449. PMID: 31245529.
    Citations:    
  7. Magnain C, Augustinack JC, Tirrell L, Fogarty M, Frosch MP, Boas D, Fischl B, Rockland KS. Colocalization of neurons in optical coherence microscopy and Nissl-stained histology in Brodmann's area 32 and area 21. Brain Struct Funct. 2019 Jan; 224(1):351-362. PMID: 30328512.
    Citations:    Fields:    
  8. Edlow BL, Keene CD, Perl DP, Iacono D, Folkerth RD, Stewart W, Mac Donald CL, Augustinack J, Diaz-Arrastia R, Estrada C, Flannery E, Gordon WA, Grabowski TJ, Hansen K, Hoffman J, Kroenke C, Larson EB, Lee P, Mareyam A, McNab JA, McPhee J, Moreau AL, Renz A, Richmire K, Stevens A, Tang CY, Tirrell LS, Trittschuh EH, van der Kouwe A, Varjabedian A, Wald LL, Wu O, Yendiki A, Young L, Zöllei L, Fischl B, Crane PK, Dams-O'Connor K. Multimodal Characterization of the Late Effects of Traumatic Brain Injury: A Methodological Overview of the Late Effects of Traumatic Brain Injury Project. J Neurotrauma. 2018 07 15; 35(14):1604-1619. PMID: 29421973.
    Citations:    Fields:    
  9. Wang H, Magnain C, Wang R, Dubb J, Varjabedian A, Tirrell LS, Stevens A, Augustinack JC, Konukoglu E, Aganj I, Frosch MP, Schmahmann JD, Fischl B, Boas DA. as-PSOCT: Volumetric microscopic imaging of human brain architecture and connectivity. Neuroimage. 2018 01 15; 165:56-68. PMID: 29017866.
    Citations: 1     Fields:    Translation:Humans
  10. Saygin ZM, Kliemann D, Iglesias JE, van der Kouwe AJW, Boyd E, Reuter M, Stevens A, Van Leemput K, McKee A, Frosch MP, Fischl B, Augustinack JC. High-resolution magnetic resonance imaging reveals nuclei of the human amygdala: manual segmentation to automatic atlas. Neuroimage. 2017 07 15; 155:370-382. PMID: 28479476.
    Citations: 7     Fields:    Translation:Humans
  11. Lindemer ER, Greve DN, Fischl BR, Augustinack JC, Salat DH. Regional staging of white matter signal abnormalities in aging and Alzheimer's disease. Neuroimage Clin. 2017; 14:156-165. PMID: 28180074.
    Citations: 2     Fields:    Translation:Humans
  12. Lindemer ER, Greve DN, Fischl B, Augustinack JC, Salat DH. Differential Regional Distribution of Juxtacortical White Matter Signal Abnormalities in Aging and Alzheimer's Disease. J Alzheimers Dis. 2017; 57(1):293-303. PMID: 28222518.
    Citations: 2     Fields:    Translation:Humans
  13. Wisse LEM, Daugherty AM, Olsen RK, Berron D, Carr VA, Stark CEL, Amaral RSC, Amunts K, Augustinack JC, Bender AR, Bernstein JD, Boccardi M, Bocchetta M, Burggren A, Chakravarty MM, Chupin M, Ekstrom A, de Flores R, Insausti R, Kanel P, Kedo O, Kennedy KM, Kerchner GA, LaRocque KF, Liu X, Maass A, Malykhin N, Mueller SG, Ofen N, Palombo DJ, Parekh MB, Pluta JB, Pruessner JC, Raz N, Rodrigue KM, Schoemaker D, Shafer AT, Steve TA, Suthana N, Wang L, Winterburn JL, Yassa MA, Yushkevich PA, la Joie R. A harmonized segmentation protocol for hippocampal and parahippocampal subregions: Why do we need one and what are the key goals? Hippocampus. 2017 01; 27(1):3-11. PMID: 27862600.
    Citations: 10     Fields:    Translation:Humans
  14. Iglesias JE, Van Leemput K, Augustinack J, Insausti R, Fischl B, Reuter M. Bayesian longitudinal segmentation of hippocampal substructures in brain MRI using subject-specific atlases. Neuroimage. 2016 Nov 01; 141:542-555. PMID: 27426838.
    Citations: 4     Fields:    Translation:Humans
  15. Augustinack JC, van der Kouwe AJ. Postmortem imaging and neuropathologic correlations. Handb Clin Neurol. 2016; 136:1321-39. PMID: 27430472.
    Citations:    Fields:    Translation:Humans
  16. Bilgic B, Xie L, Dibb R, Langkammer C, Mutluay A, Ye H, Polimeni JR, Augustinack J, Liu C, Wald LL, Setsompop K. Rapid multi-orientation quantitative susceptibility mapping. Neuroimage. 2016 Jan 15; 125:1131-1141. PMID: 26277773.
    Citations: 14     Fields:    Translation:Humans
  17. Raslau FD, Augustinack JC, Klein AP, Ulmer JL, Mathews VP, Mark LP. Memory Part 3: The Role of the Fornix and Clinical Cases. AJNR Am J Neuroradiol. 2015 Sep; 36(9):1604-8. PMID: 26045575.
    Citations:    Fields:    
  18. Iglesias JE, Augustinack JC, Nguyen K, Player CM, Player A, Wright M, Roy N, Frosch MP, McKee AC, Wald LL, Fischl B, Van Leemput K. A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI. Neuroimage. 2015 Jul 15; 115:117-37. PMID: 25936807.
    Citations: 70     Fields:    Translation:Humans
  19. Magnain C, Augustinack JC, Konukoglu E, Frosch MP, Sakadžic S, Varjabedian A, Garcia N, Wedeen VJ, Boas DA, Fischl B. Optical coherence tomography visualizes neurons in human entorhinal cortex. Neurophotonics. 2015 Feb 09; 2(1):015004. PMID: 25741528.
    Citations: 11     
  20. Yushkevich PA, Amaral RS, Augustinack JC, Bender AR, Bernstein JD, Boccardi M, Bocchetta M, Burggren AC, Carr VA, Chakravarty MM, Chételat G, Daugherty AM, Davachi L, Ding SL, Ekstrom A, Geerlings MI, Hassan A, Huang Y, Iglesias JE, La Joie R, Kerchner GA, LaRocque KF, Libby LA, Malykhin N, Mueller SG, Olsen RK, Palombo DJ, Parekh MB, Pluta JB, Preston AR, Pruessner JC, Ranganath C, Raz N, Schlichting ML, Schoemaker D, Singh S, Stark CE, Suthana N, Tompary A, Turowski MM, Van Leemput K, Wagner AD, Wang L, Winterburn JL, Wisse LE, Yassa MA, Zeineh MM. Quantitative comparison of 21 protocols for labeling hippocampal subfields and parahippocampal subregions in in vivo MRI: towards a harmonized segmentation protocol. Neuroimage. 2015 May 01; 111:526-41. PMID: 25596463.
    Citations: 43     Fields:    Translation:Humans
  21. Augustinack JC, van der Kouwe AJ, Salat DH, Benner T, Stevens AA, Annese J, Fischl B, Frosch MP, Corkin S. H.M.'s contributions to neuroscience: a review and autopsy studies. Hippocampus. 2014 Nov; 24(11):1267-86. PMID: 25154857.
    Citations: 12     Fields:    Translation:Humans
  22. Augustinack JC, van der Kouwe AJ, Fischl B. Medial temporal cortices in ex vivo magnetic resonance imaging. J Comp Neurol. 2013 Dec 15; 521(18):4177-88. PMID: 23881818.
    Citations: 4     Fields:    Translation:HumansAnimals
  23. Magnain C, Augustinack JC, Reuter M, Wachinger C, Frosch MP, Ragan T, Akkin T, Wedeen VJ, Boas DA, Fischl B. Blockface histology with optical coherence tomography: a comparison with Nissl staining. Neuroimage. 2014 Jan 01; 84:524-33. PMID: 24041872.
    Citations: 22     Fields:    Translation:HumansCells
  24. Augustinack JC, Magnain C, Reuter M, van der Kouwe AJ, Boas D, Fischl B. MRI parcellation of ex vivo medial temporal lobe. Neuroimage. 2014 Jun; 93 Pt 2:252-9. PMID: 23702414.
    Citations: 12     Fields:    Translation:Humans
  25. McNab JA, Polimeni JR, Wang R, Augustinack JC, Fujimoto K, Stevens A, Triantafyllou C, Janssens T, Farivar R, Folkerth RD, Vanduffel W, Wald LL. Corrigendum to "Surface based analysis of diffusion orientation for identifying architectonic domains in the in vivo human cortex" [NeuroImage 69 (2013) 87-100]. Neuroimage. 2013 Nov 01; 81:505. PMID: 30180375.
    Citations:    Fields:    
  26. Ziegler DA, Augustinack JC. Harnessing advances in structural MRI to enhance research on Parkinson's disease. Imaging Med. 2013 Apr; 5(2):91-94. PMID: 23687517.
    Citations: 3     
  27. McNab JA, Polimeni JR, Wang R, Augustinack JC, Fujimoto K, Stevens A, Triantafyllou C, Janssens T, Farivar R, Folkerth RD, Vanduffel W, Wald LL. Surface based analysis of diffusion orientation for identifying architectonic domains in the in vivo human cortex. Neuroimage. 2013 Apr 01; 69:87-100. PMID: 23247190.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  28. Augustinack JC, Huber KE, Stevens AA, Roy M, Frosch MP, van der Kouwe AJ, Wald LL, Van Leemput K, McKee AC, Fischl B. Predicting the location of human perirhinal cortex, Brodmann's area 35, from MRI. Neuroimage. 2013 Jan 01; 64:32-42. PMID: 22960087.
    Citations: 28     Fields:    Translation:Humans
  29. Augustinack JC, Huber KE, Postelnicu GM, Kakunoori S, Wang R, van der Kouwe AJ, Wald LL, Stein TD, Frosch MP, Fischl B. Entorhinal verrucae geometry is coincident and correlates with Alzheimer's lesions: a combined neuropathology and high-resolution ex vivo MRI analysis. Acta Neuropathol. 2012 Jan; 123(1):85-96. PMID: 22160360.
    Citations: 6     Fields:    Translation:HumansCells
  30. Yendiki A, Panneck P, Srinivasan P, Stevens A, Zöllei L, Augustinack J, Wang R, Salat D, Ehrlich S, Behrens T, Jbabdi S, Gollub R, Fischl B. Automated probabilistic reconstruction of white-matter pathways in health and disease using an atlas of the underlying anatomy. Front Neuroinform. 2011; 5:23. PMID: 22016733.
    Citations: 101     
  31. Saygin ZM, Osher DE, Augustinack J, Fischl B, Gabrieli JD. Connectivity-based segmentation of human amygdala nuclei using probabilistic tractography. Neuroimage. 2011 Jun 01; 56(3):1353-61. PMID: 21396459.
    Citations: 34     Fields:    Translation:Humans
  32. Ghosh SS, Kakunoori S, Augustinack J, Nieto-Castanon A, Kovelman I, Gaab N, Christodoulou JA, Triantafyllou C, Gabrieli JD, Fischl B. Evaluating the validity of volume-based and surface-based brain image registration for developmental cognitive neuroscience studies in children 4 to 11 years of age. Neuroimage. 2010 Oct 15; 53(1):85-93. PMID: 20621657.
    Citations: 61     Fields:    Translation:Humans
  33. Augustinack JC, Helmer K, Huber KE, Kakunoori S, Zöllei L, Fischl B. Direct visualization of the perforant pathway in the human brain with ex vivo diffusion tensor imaging. Front Hum Neurosci. 2010; 4:42. PMID: 20577631.
    Citations: 30     
  34. Van Leemput K, Bakkour A, Benner T, Wiggins G, Wald LL, Augustinack J, Dickerson BC, Golland P, Fischl B. Automated segmentation of hippocampal subfields from ultra-high resolution in vivo MRI. Hippocampus. 2009 Jun; 19(6):549-57. PMID: 19405131.
    Citations: 121     Fields:    Translation:Humans
  35. Fischl B, Stevens AA, Rajendran N, Yeo BT, Greve DN, Van Leemput K, Polimeni JR, Kakunoori S, Buckner RL, Pacheco J, Salat DH, Melcher J, Frosch MP, Hyman BT, Grant PE, Rosen BR, van der Kouwe AJ, Wiggins GC, Wald LL, Augustinack JC. Predicting the location of entorhinal cortex from MRI. Neuroimage. 2009 Aug 01; 47(1):8-17. PMID: 19376238.
    Citations: 34     Fields:    Translation:Humans
  36. Hinds O, Polimeni JR, Rajendran N, Balasubramanian M, Wald LL, Augustinack JC, Wiggins G, Rosas HD, Fischl B, Schwartz EL. The intrinsic shape of human and macaque primary visual cortex. Cereb Cortex. 2008 Nov; 18(11):2586-95. PMID: 18308709.
    Citations: 13     Fields:    Translation:HumansAnimals
  37. Van Leemput K, Bakkour A, Benner T, Wiggins G, Wald LL, Augustinack J, Dickerson BC, Golland P, Fischl B. Model-based segmentation of hippocampal subfields in ultra-high resolution in vivo MRI. Med Image Comput Comput Assist Interv. 2008; 11(Pt 1):235-43. PMID: 18979753.
    Citations: 10     Fields:    Translation:Humans
  38. Fischl B, Rajendran N, Busa E, Augustinack J, Hinds O, Yeo BT, Mohlberg H, Amunts K, Zilles K. Cortical folding patterns and predicting cytoarchitecture. Cereb Cortex. 2008 Aug; 18(8):1973-80. PMID: 18079129.
    Citations: 185     Fields:    Translation:Humans
  39. Hinds OP, Rajendran N, Polimeni JR, Augustinack JC, Wiggins G, Wald LL, Diana Rosas H, Potthast A, Schwartz EL, Fischl B. Accurate prediction of V1 location from cortical folds in a surface coordinate system. Neuroimage. 2008 Feb 15; 39(4):1585-99. PMID: 18055222.
    Citations: 72     Fields:    Translation:Humans
  40. Dickerson BC, Feczko E, Augustinack JC, Pacheco J, Morris JC, Fischl B, Buckner RL. Differential effects of aging and Alzheimer's disease on medial temporal lobe cortical thickness and surface area. Neurobiol Aging. 2009 Mar; 30(3):432-40. PMID: 17869384.
    Citations: 87     Fields:    Translation:Humans
  41. Feczko E, Augustinack JC, Fischl B, Dickerson BC. An MRI-based method for measuring volume, thickness and surface area of entorhinal, perirhinal, and posterior parahippocampal cortex. Neurobiol Aging. 2009 Mar; 30(3):420-31. PMID: 17850926.
    Citations: 21     Fields:    Translation:Humans
  42. Bacskai BJ, Frosch MP, Freeman SH, Raymond SB, Augustinack JC, Johnson KA, Irizarry MC, Klunk WE, Mathis CA, Dekosky ST, Greenberg SM, Hyman BT, Growdon JH. Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. Arch Neurol. 2007 Mar; 64(3):431-4. PMID: 17353389.
    Citations: 115     Fields:    Translation:Humans
  43. Ingelsson M, Ramasamy K, Cantuti-Castelvetri I, Skoglund L, Matsui T, Orne J, Kowa H, Raju S, Vanderburg CR, Augustinack JC, de Silva R, Lees AJ, Lannfelt L, Growdon JH, Frosch MP, Standaert DG, Irizarry MC, Hyman BT. No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain. Acta Neuropathol. 2006 Oct; 112(4):439-49. PMID: 16802167.
    Citations: 11     Fields:    Translation:HumansCells
  44. Augustinack JC, van der Kouwe AJ, Blackwell ML, Salat DH, Wiggins CJ, Frosch MP, Wiggins GC, Potthast A, Wald LL, Fischl BR. Detection of entorhinal layer II using 7Tesla [corrected] magnetic resonance imaging. Ann Neurol. 2005 Apr; 57(4):489-94. PMID: 15786476.
    Citations: 45     Fields:    Translation:Humans
  45. Hyman BT, Augustinack JC, Ingelsson M. Transcriptional and conformational changes of the tau molecule in Alzheimer's disease. Biochim Biophys Acta. 2005 Jan 03; 1739(2-3):150-7. PMID: 15615634.
    Citations: 14     Fields:    Translation:HumansCells
  46. Le DA, Wu Y, Huang Z, Matsushita K, Plesnila N, Augustinack JC, Hyman BT, Yuan J, Kuida K, Flavell RA, Moskowitz MA. Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):15188-93. PMID: 12415117.
    Citations: 60     Fields:    Translation:AnimalsCells
  47. Augustinack JC, Sanders JL, Tsai LH, Hyman BT. Colocalization and fluorescence resonance energy transfer between cdk5 and AT8 suggests a close association in pre-neurofibrillary tangles and neurofibrillary tangles. J Neuropathol Exp Neurol. 2002 Jun; 61(6):557-64. PMID: 12071639.
    Citations: 21     Fields:    Translation:HumansCells
  48. Block RI, O'Leary DS, Hichwa RD, Augustinack JC, Boles Ponto LL, Ghoneim MM, Arndt S, Hurtig RR, Watkins GL, Hall JA, Nathan PE, Andreasen NC. Effects of frequent marijuana use on memory-related regional cerebral blood flow. Pharmacol Biochem Behav. 2002 May; 72(1-2):237-50. PMID: 11900794.
    Citations: 38     Fields:    Translation:Humans
  49. Augustinack JC, Schneider A, Mandelkow EM, Hyman BT. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. Acta Neuropathol. 2002 Jan; 103(1):26-35. PMID: 11837744.
    Citations: 227     Fields:    Translation:HumansCells
  50. Van Hoesen GW, Augustinack JC, Dierking J, Redman SJ, Thangavel R. The parahippocampal gyrus in Alzheimer's disease. Clinical and preclinical neuroanatomical correlates. Ann N Y Acad Sci. 2000 Jun; 911:254-74. PMID: 10911879.
    Citations: 30     Fields:    Translation:HumansAnimals
  51. Block RI, O'Leary DS, Hichwa RD, Augustinack JC, Ponto LL, Ghoneim MM, Arndt S, Ehrhardt JC, Hurtig RR, Watkins GL, Hall JA, Nathan PE, Andreasen NC. Cerebellar hypoactivity in frequent marijuana users. Neuroreport. 2000 Mar 20; 11(4):749-53. PMID: 10757513.
    Citations: 26     Fields:    Translation:Humans
  52. Block RI, O'Leary DS, Ehrhardt JC, Augustinack JC, Ghoneim MM, Arndt S, Hall JA. Effects of frequent marijuana use on brain tissue volume and composition. Neuroreport. 2000 Feb 28; 11(3):491-6. PMID: 10718301.
    Citations: 43     Fields:    Translation:Humans
  53. Van Hoesen GW, Augustinack JC, Redman SJ. Ventromedial temporal lobe pathology in dementia, brain trauma, and schizophrenia. Ann N Y Acad Sci. 1999 Jun 29; 877:575-94. PMID: 10415672.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.