Harvard Catalyst Profiles

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Mark Evan Lindsay, M.D., Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL130113 (LINDSAY, MARK E) Jan 15, 2016 - Dec 31, 2021
    NIH
    The Role of HDAC9/MITR in the Pathogenesis of Thoracic Aortic Aneurysm (TAA)
    Role: Principal Investigator
  2. K08HL107738 (LINDSAY, MARK E) May 16, 2011 - Apr 30, 2014
    NIH
    Development Underpinnings of Acquired Aortic Aneurysm in Marfan Syndrome
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zekavat SM, Chou EL, Zekavat M, Pampana A, Paruchuri K, Lino Cardenas CL, Koyama S, Ghazzawi Y, Kii E, Uddin MM, Pirruccello J, Zhao H, Wood M, Natarajan P, Lindsay ME. Fibrillar Collagen Variants in Spontaneous Coronary Artery Dissection. JAMA Cardiol. 2022 Apr 01; 7(4):396-406. PMID: 35234813.
    Citations:    Fields:    
  2. Cappuccio G, Brunetti-Pierri N, Clift P, Learn C, Dykes JC, Mercer CL, Callewaert B, Meerschaut I, Spinelli AM, Bruno I, Gillespie MJ, Dorfman AT, Grimberg A, Lindsay ME, Lin AE. Expanded cardiovascular phenotype of Myhre syndrome includes tetralogy of Fallot suggesting a role for SMAD4 in human neural crest defects. Am J Med Genet A. 2022 May; 188(5):1384-1395. PMID: 35025139.
    Citations:    Fields:    
  3. Chou EL, Lino Cardenas CL, Chaffin M, Arduini AD, Juric D, Stone JR, LaMuraglia GM, Eagleton MJ, Conrad MF, Isselbacher EM, Ellinor PT, Lindsay ME. Vascular smooth muscle cell phenotype switching in carotid atherosclerosis. JVS Vasc Sci. 2022; 3:41-47. PMID: 35128489.
    Citations:    
  4. Pirruccello JP, Chaffin MD, Chou EL, Fleming SJ, Lin H, Nekoui M, Khurshid S, Friedman SF, Bick AG, Arduini A, Weng LC, Choi SH, Akkad AD, Batra P, Tucker NR, Hall AW, Roselli C, Benjamin EJ, Vellarikkal SK, Gupta RM, Stegmann CM, Juric D, Stone JR, Vasan RS, Ho JE, Hoffmann U, Lubitz SA, Philippakis AA, Lindsay ME, Ellinor PT. Deep learning enables genetic analysis of the human thoracic aorta. Nat Genet. 2022 01; 54(1):40-51. PMID: 34837083.
    Citations: 1     Fields:    Translation:HumansCells
  5. Malhotra R, Nicholson CJ, Wang D, Bhambhani V, Paniagua S, Slocum C, Sigurslid HH, Lino Cardenas CL, Li R, Boerboom SL, Chen YC, Hwang SJ, Yao C, Ichinose F, Bloch DB, Lindsay ME, Lewis GD, Aragam JR, Hoffmann U, Mitchell GF, Hamburg NM, Vasan RS, Benjamin EJ, Larson MG, Zapol WM, Cheng S, Roh JD, O'Donnell CJ, Nguyen C, Levy D, Ho JE. Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction. Arterioscler Thromb Vasc Biol. 2022 02; 42(2):e61-e73. PMID: 34809448.
    Citations: 1     Fields:    Translation:HumansAnimals
  6. Aguilar-Pineda JA, Albaghdadi M, Jiang W, Vera-Lopez KJ, Nieto-Montesinos R, Alvarez KLF, Davila Del-Carpio G, Gómez B, Lindsay ME, Malhotra R, Lino Cardenas CL. Structural and Functional Analysis of Female Sex Hormones against SARS-CoV-2 Cell Entry. Int J Mol Sci. 2021 Oct 26; 22(21). PMID: 34768939.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Lindsay ME, Dudzinski DM, Yoon BC, Jaff MR, Thakuria JV. Case 30-2021: A 47-Year-Old Man with Recurrent Unilateral Head and Neck Pain. N Engl J Med. 2021 Sep 30; 385(14):1317-1325. PMID: 34587390.
    Citations:    Fields:    Translation:Humans
  8. Aguilar-Pineda JA, Vera-Lopez KJ, Shrivastava P, Chávez-Fumagalli MA, Nieto-Montesinos R, Alvarez-Fernandez KL, Goyzueta Mamani LD, Davila Del-Carpio G, Gomez-Valdez B, Miller CL, Malhotra R, Lindsay ME, Lino Cardenas CL. Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease. iScience. 2021 Sep 24; 24(9):102993. PMID: 34505007.
    Citations: 2     
  9. Oller J, Gabandé-Rodríguez E, Ruiz-Rodríguez MJ, Desdín-Micó G, Aranda JF, Rodrigues-Diez R, Ballesteros-Martínez C, Blanco EM, Roldan-Montero R, Acuña P, Forteza Gil A, Martín-López CE, Nistal JF, Lino Cardenas CL, Lindsay ME, Martín-Ventura JL, Briones AM, Redondo JM, Mittelbrunn M. Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm. Circulation. 2021 05 25; 143(21):2091-2109. PMID: 33709773.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  10. Lin AE, Brunetti-Pierri N, Callewaert B, Cormier-Daire V, Douzgou S, Kinane TB, Lindsay ME, Starr LJ. Lack of resemblance between Myhre syndrome and other "segmental progeroid" syndromes warrants restraint in applying this classification. Geroscience. 2021 04; 43(2):459-461. PMID: 33630210.
    Citations:    Fields:    Translation:Humans
  11. Harris SL, Lindsay ME. Role of Clinical Genetic Testing in the Management of Aortopathies. Curr Cardiol Rep. 2021 01 21; 23(2):10. PMID: 33475873.
    Citations:    Fields:    Translation:Humans
  12. Aguilar-Pineda JA, Albaghdadi M, Jiang W, Lopez KJV, Del-Carpio GD, Valdez BG, Lindsay ME, Malhotra R, Lino Cardenas CL. Structural and functional analysis of female sex hormones against SARS-Cov2 cell entry. bioRxiv. 2020 Jul 29. PMID: 32766583.
    Citations:    
  13. Chowdhury MM, Singh K, Albaghdadi MS, Khraishah H, Mauskapf A, Kessinger CW, Osborn EA, Kellnberger S, Piao Z, Lino Cardenas CL, Grau MS, Jaff MR, Rosenfield K, Libby P, Edelman ER, Lindsay ME, Tearney GJ, Jaffer FA. Paclitaxel Drug-Coated Balloon Angioplasty Suppresses Progression and Inflammation of Experimental Atherosclerosis in Rabbits. JACC Basic Transl Sci. 2020 Jul; 5(7):685-695. PMID: 32760856.
    Citations: 4     
  14. Chou EL, Lindsay ME. The genetics of aortopathies: Hereditary thoracic aortic aneurysms and dissections. Am J Med Genet C Semin Med Genet. 2020 03; 184(1):136-148. PMID: 32034893.
    Citations: 3     Fields:    Translation:HumansCells
  15. Lin AE, Alali A, Starr LJ, Shah N, Beavis A, Pereira EM, Lindsay ME, Klugman S. Gain-of-function pathogenic variants in SMAD4 are associated with neoplasia in Myhre syndrome. Am J Med Genet A. 2020 02; 182(2):328-337. PMID: 31837202.
    Citations: 4     Fields:    Translation:Humans
  16. Malhotra R, Mauer AC, Lino Cardenas CL, Guo X, Yao J, Zhang X, Wunderer F, Smith AV, Wong Q, Pechlivanis S, Hwang SJ, Wang J, Lu L, Nicholson CJ, Shelton G, Buswell MD, Barnes HJ, Sigurslid HH, Slocum C, Rourke CO, Rhee DK, Bagchi A, Nigwekar SU, Buys ES, Campbell CY, Harris T, Budoff M, Criqui MH, Rotter JI, Johnson AD, Song C, Franceschini N, Debette S, Hoffmann U, Kälsch H, Nöthen MM, Sigurdsson S, Freedman BI, Bowden DW, Jöckel KH, Moebus S, Erbel R, Feitosa MF, Gudnason V, Thanassoulis G, Zapol WM, Lindsay ME, Bloch DB, Post WS, O'Donnell CJ. HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype. Nat Genet. 2019 11; 51(11):1580-1587. PMID: 31659325.
    Citations: 19     Fields:    Translation:HumansAnimals
  17. Kremer TM, Lindsay ME, Kinane TB, Hawley MH, Little BP, Mino-Kenudson M. Case 28-2019: A 22-Year-Old Woman with Dyspnea and Chest Pain. N Engl J Med. 2019 09 12; 381(11):1059-1067. PMID: 31509678.
    Citations: 2     Fields:    Translation:HumansCells
  18. Boileau A, Lino Cardenas CL, Courtois A, Zhang L, Rodosthenous RS, Das S, Sakalihasan N, Michel JB, Lindsay ME, Devaux Y. MiR-574-5p: A Circulating Marker of Thoracic Aortic Aneurysm. Int J Mol Sci. 2019 08 12; 20(16). PMID: 31409059.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  19. Duran JM, Naderi S, Vidula M, Michalak N, Chi G, Lindsay M, Ghoshhajra B, Gibson CM, Wood MJ. Spontaneous coronary artery dissection and its association with takotsubo syndrome: Novel insights from a tertiary center registry. Catheter Cardiovasc Interv. 2020 02 15; 95(3):485-491. PMID: 31037831.
    Citations: 7     Fields:    Translation:Humans
  20. Sharma S, Kaadan MI, Duran JM, Ponzini F, Mishra S, Tsiaras SV, Scott NS, Weinberg I, Ghoshhajra B, Lindsay M, Gibson CM, Chi G, Michalak N, Wood MJ. Risk Factors, Imaging Findings, and Sex Differences in Spontaneous Coronary Artery Dissection. Am J Cardiol. 2019 06 01; 123(11):1783-1787. PMID: 30929769.
    Citations: 10     Fields:    Translation:Humans
  21. Lino Cardenas CL, Kessinger CW, Chou EL, Ghoshhajra B, Yeri AS, Das S, Weintraub NL, Malhotra R, Jaffer FA, Lindsay ME. HDAC9 complex inhibition improves smooth muscle-dependent stenotic vascular disease. JCI Insight. 2019 01 24; 4(2). PMID: 30674723.
    Citations: 9     Fields:    
  22. MacFarlane EG, Parker SJ, Shin JY, Kang BE, Ziegler SG, Creamer TJ, Bagirzadeh R, Bedja D, Chen Y, Calderon JF, Weissler K, Frischmeyer-Guerrerio PA, Lindsay ME, Habashi JP, Dietz HC. Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome. J Clin Invest. 2019 02 01; 129(2):659-675. PMID: 30614814.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  23. Gould RA, Aziz H, Woods CE, Seman-Senderos MA, Sparks E, Preuss C, Wünnemann F, Bedja D, Moats CR, McClymont SA, Rose R, Sobreira N, Ling H, MacCarrick G, Kumar AA, Luyckx I, Cannaerts E, Verstraeten A, Björk HM, Lehsau AC, Jaskula-Ranga V, Lauridsen H, Shah AA, Bennett CL, Ellinor PT, Lin H, Isselbacher EM, Lino Cardenas CL, Butcher JT, Hughes GC, Lindsay ME, Mertens L, Franco-Cereceda A, Verhagen JMA, Wessels M, Mohamed SA, Eriksson P, Mital S, Van Laer L, Loeys BL, Andelfinger G, McCallion AS, Dietz HC. ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. Nat Genet. 2019 01; 51(1):42-50. PMID: 30455415.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  24. Aragam KG, Chaffin M, Levinson RT, McDermott G, Choi SH, Shoemaker MB, Haas ME, Weng LC, Lindsay ME, Smith JG, Newton-Cheh C, Roden DM, London B, Wells QS, Ellinor PT, Kathiresan S, Lubitz SA. Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery. Circulation. 2018 Nov 11. PMID: 30586722.
    Citations: 33     Fields:    
  25. Lindsay ME. Medical management of aortic disease in children with Marfan syndrome. Curr Opin Pediatr. 2018 10; 30(5):639-644. PMID: 30036202.
    Citations: 3     Fields:    Translation:Humans
  26. Renard M, Francis C, Ghosh R, Scott AF, Witmer PD, Adès LC, Andelfinger GU, Arnaud P, Boileau C, Callewaert BL, Guo D, Hanna N, Lindsay ME, Morisaki H, Morisaki T, Pachter N, Robert L, Van Laer L, Dietz HC, Loeys BL, Milewicz DM, De Backer J. Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection. J Am Coll Cardiol. 2018 08 07; 72(6):605-615. PMID: 30071989.
    Citations: 32     Fields:    Translation:Humans
  27. Boileau A, Lindsay ME, Michel JB, Devaux Y. Epigenetics in Ascending Thoracic Aortic Aneurysm and Dissection. Aorta (Stamford). 2018 Feb; 6(1):1-12. PMID: 30079931.
    Citations: 6     
  28. Kaadan MI, MacDonald C, Ponzini F, Duran J, Newell K, Pitler L, Lin A, Weinberg I, Wood MJ, Lindsay ME. Prospective Cardiovascular Genetics Evaluation in Spontaneous Coronary Artery Dissection. Circ Genom Precis Med. 2018 04; 11(4):e001933. PMID: 29650765.
    Citations: 17     Fields:    Translation:Humans
  29. Lino Cardenas CL, Kessinger CW, MacDonald C, Jassar AS, Isselbacher EM, Jaffer FA, Lindsay ME. Inhibition of the methyltranferase EZH2 improves aortic performance in experimental thoracic aortic aneurysm. JCI Insight. 2018 03 08; 3(5). PMID: 29515022.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  30. Lino Cardenas CL, Kessinger CW, Cheng Y, MacDonald C, MacGillivray T, Ghoshhajra B, Huleihel L, Nuri S, Yeri AS, Jaffer FA, Kaminski N, Ellinor P, Weintraub NL, Malhotra R, Isselbacher EM, Lindsay ME. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018 03 08; 9(1):1009. PMID: 29520069.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  31. Schepers D, Tortora G, Morisaki H, MacCarrick G, Lindsay M, Liang D, Mehta SG, Hague J, Verhagen J, van de Laar I, Wessels M, Detisch Y, van Haelst M, Baas A, Lichtenbelt K, Braun K, van der Linde D, Roos-Hesselink J, McGillivray G, Meester J, Maystadt I, Coucke P, El-Khoury E, Parkash S, Diness B, Risom L, Scurr I, Hilhorst-Hofstee Y, Morisaki T, Richer J, Désir J, Kempers M, Rideout AL, Horne G, Bennett C, Rahikkala E, Vandeweyer G, Alaerts M, Verstraeten A, Dietz H, Van Laer L, Loeys B. A mutation update on the LDS-associated genes TGFB2/3 and SMAD2/3. Hum Mutat. 2018 05; 39(5):621-634. PMID: 29392890.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  32. Boileau A, Lino Cardenas CL, Lindsay ME, Devaux Y. Endogenous Heparin Interferes with Quantification of MicroRNAs by RT-qPCR. Clin Chem. 2018 05; 64(5):863-865. PMID: 29483106.
    Citations: 4     Fields:    Translation:Humans
  33. Hayes SN, Kim ESH, Saw J, Adlam D, Arslanian-Engoren C, Economy KE, Ganesh SK, Gulati R, Lindsay ME, Mieres JH, Naderi S, Shah S, Thaler DE, Tweet MS, Wood MJ. Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association. Circulation. 2018 05 08; 137(19):e523-e557. PMID: 29472380.
    Citations: 187     Fields:    Translation:Humans
  34. Tsiaras SV, Safi LM, Ghoshhajra BB, Lindsay ME, Wood MJ. Case 39-2017. A 41-Year-Old Woman with Recurrent Chest Pain. N Engl J Med. 2017 12 21; 377(25):2475-2484. PMID: 29262281.
    Citations:    Fields:    Translation:Humans
  35. Tucker NR, McLellan MA, Hu D, Ye J, Parsons VA, Mills RW, Clauss S, Dolmatova E, Shea MA, Milan DJ, Scott NS, Lindsay M, Lubitz SA, Domian IJ, Stone JR, Lin H, Ellinor PT. Novel Mutation in FLNC (Filamin C) Causes Familial Restrictive Cardiomyopathy. Circ Cardiovasc Genet. 2017 Dec; 10(6). PMID: 29212899.
    Citations: 24     Fields:    Translation:HumansCells
  36. Newell K, Smith W, Ghoshhajra B, Isselbacher E, Lin A, Lindsay ME. Cervical artery dissection expands the cardiovascular phenotype in FBN1-related Weill-Marchesani syndrome. Am J Med Genet A. 2017 Sep; 173(9):2551-2556. PMID: 28696036.
    Citations: 5     Fields:    Translation:Humans
  37. Harriott AM, Zimmerman E, Singhal AB, Jaff MR, Lindsay ME, Rordorf GA. Cerebrovascular fibromuscular dysplasia: The MGH cohort and literature review. Neurol Clin Pract. 2017 Jun; 7(3):225-236. PMID: 28680766.
    Citations: 7     
  38. Jadon DR, Sengupta R, Nightingale A, Lindsay M, Korendowych E, Robinson G, Jobling A, Shaddick G, Bi J, Winchester R, Giles JT, McHugh NJ. Axial Disease in Psoriatic Arthritis study: defining the clinical and radiographic phenotype of psoriatic spondyloarthritis. Ann Rheum Dis. 2017 04; 76(4):701-707. PMID: 27913376.
    Citations: 38     Fields:    Translation:Humans
  39. Kim JB, Spotnitz M, Lindsay ME, MacGillivray TE, Isselbacher EM, Sundt TM. Risk of Aortic Dissection in the Moderately Dilated Ascending Aorta. J Am Coll Cardiol. 2016 09 13; 68(11):1209-1219. PMID: 27609684.
    Citations: 23     Fields:    Translation:Humans
  40. Isselbacher EM, Bonaca MP, Di Eusanio M, Froehlich J, Bossone E, Sechtem U, Pyeritz R, Patel H, Khoynezhad A, Eckstein HH, Jondeau G, Ramponi F, Abbasi M, Montgomery D, Nienaber CA, Eagle K, Lindsay ME. Recurrent Aortic Dissection: Observations From the International Registry of Aortic Dissection. Circulation. 2016 10 04; 134(14):1013-1024. PMID: 27587434.
    Citations: 11     Fields:    Translation:Humans
  41. Isselbacher EM, Lino Cardenas CL, Lindsay ME. Hereditary Influence in Thoracic Aortic Aneurysm and Dissection. Circulation. 2016 Jun 14; 133(24):2516-28. PMID: 27297344.
    Citations: 60     Fields:    Translation:Humans
  42. Lin AE, Michot C, Cormier-Daire V, L'Ecuyer TJ, Matherne GP, Barnes BH, Humberson JB, Edmondson AC, Zackai E, O'Connor MJ, Kaplan JD, Ebeid MR, Krier J, Krieg E, Ghoshhajra B, Lindsay ME. Gain-of-function mutations in SMAD4 cause a distinctive repertoire of cardiovascular phenotypes in patients with Myhre syndrome. Am J Med Genet A. 2016 10; 170(10):2617-31. PMID: 27302097.
    Citations: 14     Fields:    Translation:Humans
  43. Vapnik JS, Kim JB, Isselbacher EM, Ghoshhajra BB, Cheng Y, Sundt TM, MacGillivray TE, Cambria RP, Lindsay ME. Characteristics and Outcomes of Ascending Versus Descending Thoracic Aortic Aneurysms. Am J Cardiol. 2016 05 15; 117(10):1683-1690. PMID: 27015890.
    Citations: 15     Fields:    Translation:Humans
  44. Doyle JJ, Doyle AJ, Wilson NK, Habashi JP, Bedja D, Whitworth RE, Lindsay ME, Schoenhoff F, Myers L, Huso N, Bachir S, Squires O, Rusholme B, Ehsan H, Huso D, Thomas CJ, Caulfield MJ, Van Eyk JE, Judge DP, Dietz HC. A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome. Elife. 2015 10 27; 4. PMID: 26506064.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  45. Martin PS, Kloesel B, Norris RA, Lindsay M, Milan D, Body SC. Embryonic Development of the Bicuspid Aortic Valve. J Cardiovasc Dev Dis. 2015 Dec; 2(4):248-272. PMID: 28529942.
    Citations: 24     
  46. Kim JB, Kim K, Lindsay ME, MacGillivray T, Isselbacher EM, Cambria RP, Sundt TM. Risk of rupture or dissection in descending thoracic aortic aneurysm. Circulation. 2015 Oct 27; 132(17):1620-9. PMID: 26338955.
    Citations: 16     Fields:    Translation:Humans
  47. Ptaszek LM, Kim K, Spooner AE, MacGillivray TE, Cambria RP, Lindsay ME, Isselbacher EM. Marfan syndrome is associated with recurrent dissection of the dissected aorta. Ann Thorac Surg. 2015 May; 99(5):1616-23. PMID: 25818572.
    Citations: 2     Fields:    Translation:Humans
  48. Lindsay ME, Dietz HC. The genetic basis of aortic aneurysm. Cold Spring Harb Perspect Med. 2014 Sep 02; 4(9):a015909. PMID: 25183854.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  49. Gallo EM, Loch DC, Habashi JP, Calderon JF, Chen Y, Bedja D, van Erp C, Gerber EE, Parker SJ, Sauls K, Judge DP, Cooke SK, Lindsay ME, Rouf R, Myers L, ap Rhys CM, Kent KC, Norris RA, Huso DL, Dietz HC. Angiotensin II-dependent TGF-ß signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. J Clin Invest. 2014 Jan; 124(1):448-60. PMID: 24355923.
    Citations: 106     Fields:    Translation:HumansAnimalsCells
  50. Kane MS, Lindsay ME, Judge DP, Barrowman J, Ap Rhys C, Simonson L, Dietz HC, Michaelis S. LMNA-associated cardiocutaneous progeria: an inherited autosomal dominant premature aging syndrome with late onset. Am J Med Genet A. 2013 Jul; 161A(7):1599-611. PMID: 23666920.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  51. Doyle AJ, Doyle JJ, Bessling SL, Maragh S, Lindsay ME, Schepers D, Gillis E, Mortier G, Homfray T, Sauls K, Norris RA, Huso ND, Leahy D, Mohr DW, Caulfield MJ, Scott AF, Destrée A, Hennekam RC, Arn PH, Curry CJ, Van Laer L, McCallion AS, Loeys BL, Dietz HC. Mutations in the TGF-ß repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm. Nat Genet. 2012 Nov; 44(11):1249-54. PMID: 23023332.
    Citations: 102     Fields:    Translation:HumansAnimalsCells
  52. Lindsay ME, Schepers D, Bolar NA, Doyle JJ, Gallo E, Fert-Bober J, Kempers MJ, Fishman EK, Chen Y, Myers L, Bjeda D, Oswald G, Elias AF, Levy HP, Anderlid BM, Yang MH, Bongers EM, Timmermans J, Braverman AC, Canham N, Mortier GR, Brunner HG, Byers PH, Van Eyk J, Van Laer L, Dietz HC, Loeys BL. Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm. Nat Genet. 2012 Jul 08; 44(8):922-7. PMID: 22772368.
    Citations: 164     Fields:    Translation:HumansAnimalsCells
  53. Lindsay ME, Dietz HC. Lessons on the pathogenesis of aneurysm from heritable conditions. Nature. 2011 May 19; 473(7347):308-16. PMID: 21593863.
    Citations: 166     Fields:    Translation:HumansAnimals
  54. Holm TM, Habashi JP, Doyle JJ, Bedja D, Chen Y, van Erp C, Lindsay ME, Kim D, Schoenhoff F, Cohn RD, Loeys BL, Thomas CJ, Patnaik S, Marugan JJ, Judge DP, Dietz HC. Noncanonical TGFß signaling contributes to aortic aneurysm progression in Marfan syndrome mice. Science. 2011 Apr 15; 332(6027):358-61. PMID: 21493862.
    Citations: 219     Fields:    Translation:AnimalsCells
  55. Mukherjee D, Lindsay M, Zhang Y, Lardaro T, Osen H, Chang DC, Brenner JI, Abdullah F. Analysis of 8681 neonates with transposition of the great arteries: outcomes with and without Rashkind balloon atrial septostomy. Cardiol Young. 2010 Aug; 20(4):373-80. PMID: 20470448.
    Citations: 7     Fields:    Translation:Humans
  56. Hansson EM, Lindsay ME, Chien KR. Regeneration next: toward heart stem cell therapeutics. Cell Stem Cell. 2009 Oct 02; 5(4):364-77. PMID: 19796617.
    Citations: 75     Fields:    Translation:HumansCells
  57. Lindsay ME, Plafker K, Smith AE, Clurman BE, Macara IG. Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import. Cell. 2002 Aug 09; 110(3):349-60. PMID: 12176322.
    Citations: 47     Fields:    Translation:HumansCells
  58. Nemergut ME, Lindsay ME, Brownawell AM, Macara IG. Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor. J Biol Chem. 2002 May 17; 277(20):17385-8. PMID: 11932251.
    Citations: 25     Fields:    Translation:HumansCells
  59. Buss F, Arden SD, Lindsay M, Luzio JP, Kendrick-Jones J. Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis. EMBO J. 2001 Jul 16; 20(14):3676-84. PMID: 11447109.
    Citations: 107     Fields:    Translation:HumansAnimalsCells
  60. Lindsay ME, Holaska JM, Welch K, Paschal BM, Macara IG. Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export. J Cell Biol. 2001 Jun 25; 153(7):1391-402. PMID: 11425870.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  61. MacAry PA, Lindsay M, Scott MA, Craig JI, Luzio JP, Lehner PJ. Mobilization of MHC class I molecules from late endosomes to the cell surface following activation of CD34-derived human Langerhans cells. Proc Natl Acad Sci U S A. 2001 Mar 27; 98(7):3982-7. PMID: 11274420.
    Citations: 28     Fields:    Translation:HumansCells
  62. Pol A, Luetterforst R, Lindsay M, Heino S, Ikonen E, Parton RG. A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance. J Cell Biol. 2001 Mar 05; 152(5):1057-70. PMID: 11238460.
    Citations: 98     Fields:    Translation:AnimalsCells
  63. Gillooly DJ, Morrow IC, Lindsay M, Gould R, Bryant NJ, Gaullier JM, Parton RG, Stenmark H. Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J. 2000 Sep 01; 19(17):4577-88. PMID: 10970851.
    Citations: 442     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.