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George Liang King, M.D.

Concepts

This page shows the publications George King has written about Retina.
Connection Strength

1.842
  1. Retinol binding protein 3 is increased in the retina of patients with diabetes resistant to diabetic retinopathy. Sci Transl Med. 2019 07 03; 11(499).
    View in: PubMed
    Score: 0.358
  2. Retinal not systemic oxidative and inflammatory stress correlated with VEGF expression in rodent models of insulin resistance and diabetes. Invest Ophthalmol Vis Sci. 2012 Dec 19; 53(13):8424-32.
    View in: PubMed
    Score: 0.228
  3. Bactericidal/permeability-increasing protein's signaling pathways and its retinal trophic and anti-angiogenic effects. FASEB J. 2006 Oct; 20(12):2058-67.
    View in: PubMed
    Score: 0.148
  4. Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes. Diabetes. 2003 Mar; 52(3):838-45.
    View in: PubMed
    Score: 0.115
  5. Response to Letter to the Editor from Brunerova et al: "Association of Cognitive Function and Retinal Neural and Vascular Structure in Type 1 Diabetes". J Clin Endocrinol Metab. 2021 08 18; 106(9):e3789-e3790.
    View in: PubMed
    Score: 0.104
  6. Association of Cognitive Function and Retinal Neural and Vascular Structure in Type 1 Diabetes. J Clin Endocrinol Metab. 2021 03 25; 106(4):1139-1149.
    View in: PubMed
    Score: 0.101
  7. Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathways in retinal vascular cells. J Biol Chem. 2000 Dec 29; 275(52):40725-31.
    View in: PubMed
    Score: 0.099
  8. Specific retinal diacylglycerol and protein kinase C beta isoform modulation mimics abnormal retinal hemodynamics in diabetic rats. Invest Ophthalmol Vis Sci. 1997 Dec; 38(13):2711-20.
    View in: PubMed
    Score: 0.080
  9. Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor. Diabetes. 1997 Sep; 46(9):1473-80.
    View in: PubMed
    Score: 0.079
  10. Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia. Diabetes. 1994 Sep; 43(9):1122-9.
    View in: PubMed
    Score: 0.064
  11. Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation. Am J Physiol. 1993 Nov; 265(5 Pt 1):E783-93.
    View in: PubMed
    Score: 0.060
  12. Induction of resistance to endothelin-1's biochemical actions by elevated glucose levels in retinal pericytes. Diabetes. 1992 Dec; 41(12):1533-9.
    View in: PubMed
    Score: 0.057
  13. Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications. Proc Natl Acad Sci U S A. 1989 07; 86(13):5141-5.
    View in: PubMed
    Score: 0.045
  14. Differential regulation of protein kinase C and (Na,K)-adenosine triphosphatase activities by elevated glucose levels in retinal capillary endothelial cells. J Clin Invest. 1989 Jan; 83(1):90-4.
    View in: PubMed
    Score: 0.043
  15. Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation. Diabetes. 2003 Mar; 52(3):829-37.
    View in: PubMed
    Score: 0.029
  16. Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue. Circulation. 2002 Jan 22; 105(3):373-9.
    View in: PubMed
    Score: 0.027
  17. Stretch-induced retinal vascular endothelial growth factor expression is mediated by phosphatidylinositol 3-kinase and protein kinase C (PKC)-zeta but not by stretch-induced ERK1/2, Akt, Ras, or classical/novel PKC pathways. J Biol Chem. 2002 Jan 11; 277(2):1047-57.
    View in: PubMed
    Score: 0.026
  18. Prevention of diabetes-induced abnormal retinal blood flow by treatment with d-alpha-tocopherol. Biofactors. 1998; 7(1-2):55-67.
    View in: PubMed
    Score: 0.020
  19. Regulation of retinal hemodynamics in diabetic rats by increased expression and action of endothelin-1. Invest Ophthalmol Vis Sci. 1996 Nov; 37(12):2504-18.
    View in: PubMed
    Score: 0.019
  20. Identification and characterization of vascular endothelial growth factor receptor (Flt) in bovine retinal pericytes. Diabetes. 1996 Aug; 45(8):1016-23.
    View in: PubMed
    Score: 0.018
  21. Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor. Science. 1996 May 03; 272(5262):728-31.
    View in: PubMed
    Score: 0.018
  22. Vitamin E prevents diabetes-induced abnormal retinal blood flow via the diacylglycerol-protein kinase C pathway. Am J Physiol. 1995 Aug; 269(2 Pt 1):E239-46.
    View in: PubMed
    Score: 0.017
  23. The in vivo effect of endothelins on retinal circulation in nondiabetic and diabetic rats. Invest Ophthalmol Vis Sci. 1995 Mar; 36(3):596-607.
    View in: PubMed
    Score: 0.017
  24. Identification of multiple genes in bovine retinal pericytes altered by exposure to elevated levels of glucose by using mRNA differential display. Proc Natl Acad Sci U S A. 1994 Jun 21; 91(13):6231-5.
    View in: PubMed
    Score: 0.016
  25. Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications. Proc Natl Acad Sci U S A. 2008 May 13; 105(19):6998-7003.
    View in: PubMed
    Score: 0.010
  26. A monoclonal antibody (3G5)-defined ganglioside antigen is expressed on the cell surface of microvascular pericytes. J Exp Med. 1988 Mar 01; 167(3):1003-15.
    View in: PubMed
    Score: 0.010
  27. Regulation of vascular permeability in cell culture. Diabetes. 1987 Dec; 36(12):1460-7.
    View in: PubMed
    Score: 0.010
  28. Characterization of the receptors for insulin and the insulin-like growth factors on micro- and macrovascular tissues. Endocrinology. 1985 Sep; 117(3):1222-9.
    View in: PubMed
    Score: 0.009
  29. Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta. J Clin Invest. 1985 Mar; 75(3):1028-36.
    View in: PubMed
    Score: 0.008
  30. The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance. J Clin Invest. 2003 May; 111(9):1373-80.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.