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George Liang King, M.D.

Concepts

This page shows the publications George King has written about Insulin Resistance.
Connection Strength

3.960
  1. Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes. Nat Commun. 2019 09 27; 10(1):4427.
    View in: PubMed
    Score: 0.320
  2. Letter by Rask-Madsen et al Regarding Article, "Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop". Circ Res. 2017 02 17; 120(4):e2-e3.
    View in: PubMed
    Score: 0.267
  3. Selective Insulin Resistance and the Development of Cardiovascular Diseases in Diabetes: The 2015 Edwin Bierman Award Lecture. Diabetes. 2016 06; 65(6):1462-71.
    View in: PubMed
    Score: 0.254
  4. Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance. Diabetes. 2016 09; 65(9):2760-71.
    View in: PubMed
    Score: 0.254
  5. Improvement of insulin sensitivity by isoenergy high carbohydrate traditional Asian diet: a randomized controlled pilot feasibility study. PLoS One. 2014; 9(9):e106851.
    View in: PubMed
    Score: 0.226
  6. Obesity-associated Gingival Vascular Inflammation and Insulin Resistance. J Dent Res. 2014 Jun; 93(6):596-601.
    View in: PubMed
    Score: 0.219
  7. Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells. Mol Cell Biol. 2013 Aug; 33(16):3227-41.
    View in: PubMed
    Score: 0.207
  8. Induction of vascular insulin resistance and endothelin-1 expression and acceleration of atherosclerosis by the overexpression of protein kinase C-ß isoform in the endothelium. Circ Res. 2013 Aug 02; 113(4):418-27.
    View in: PubMed
    Score: 0.207
  9. Retinal not systemic oxidative and inflammatory stress correlated with VEGF expression in rodent models of insulin resistance and diabetes. Invest Ophthalmol Vis Sci. 2012 Dec 19; 53(13):8424-32.
    View in: PubMed
    Score: 0.200
  10. Hyperinsulinemia does not change atherosclerosis development in apolipoprotein E null mice. Arterioscler Thromb Vasc Biol. 2012 May; 32(5):1124-31.
    View in: PubMed
    Score: 0.190
  11. Glomerular-specific protein kinase C-ß-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity. Kidney Int. 2011 Apr; 79(8):883-96.
    View in: PubMed
    Score: 0.175
  12. Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes. Nat Clin Pract Endocrinol Metab. 2007 Jan; 3(1):46-56.
    View in: PubMed
    Score: 0.132
  13. Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance. Diabetes. 2006 Mar; 55(3):691-8.
    View in: PubMed
    Score: 0.125
  14. Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia. Arterioscler Thromb Vasc Biol. 2006 Apr; 26(4):787-93.
    View in: PubMed
    Score: 0.124
  15. Proatherosclerotic mechanisms involving protein kinase C in diabetes and insulin resistance. Arterioscler Thromb Vasc Biol. 2005 Mar; 25(3):487-96.
    View in: PubMed
    Score: 0.115
  16. Hyperglycemia-induced oxidative stress in diabetic complications. Histochem Cell Biol. 2004 Oct; 122(4):333-8.
    View in: PubMed
    Score: 0.112
  17. Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue. Circulation. 2002 Jan 22; 105(3):373-9.
    View in: PubMed
    Score: 0.094
  18. Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats. J Clin Invest. 1999 Aug; 104(4):447-57.
    View in: PubMed
    Score: 0.079
  19. Theoretical mechanisms by which hyperglycemia and insulin resistance could cause cardiovascular diseases in diabetes. Diabetes Care. 1999 Apr; 22 Suppl 3:C31-7.
    View in: PubMed
    Score: 0.077
  20. Exogenous Insulin Infusion Can Decrease Atherosclerosis in Diabetic Rodents by Improving Lipids, Inflammation, and Endothelial Function. Arterioscler Thromb Vasc Biol. 2018 01; 38(1):92-101.
    View in: PubMed
    Score: 0.070
  21. Regulation of Macrophage Apoptosis and Atherosclerosis by Lipid-Induced PKCd Isoform Activation. Circ Res. 2017 Oct 27; 121(10):1153-1167.
    View in: PubMed
    Score: 0.069
  22. SHP-1 activation inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and diabetes. Diabetologia. 2017 03; 60(3):585-596.
    View in: PubMed
    Score: 0.066
  23. A cross-sectional characterization of insulin resistance by phenotype and insulin clamp in East Asian Americans with type 1 and type 2 diabetes. PLoS One. 2011; 6(12):e28311.
    View in: PubMed
    Score: 0.047
  24. PKCd regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans. J Clin Invest. 2011 Jun; 121(6):2504-17.
    View in: PubMed
    Score: 0.045
  25. Diabetes: Podocytes lose their footing. Nature. 2010 Nov 04; 468(7320):42-4.
    View in: PubMed
    Score: 0.043
  26. The role of inflammatory cytokines in diabetes and its complications. J Periodontol. 2008 Aug; 79(8 Suppl):1527-34.
    View in: PubMed
    Score: 0.037
  27. Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis. Cell Metab. 2008 Feb; 7(2):125-34.
    View in: PubMed
    Score: 0.036
  28. Oxidative stress and antioxidant treatment in diabetes. Ann N Y Acad Sci. 2004 Dec; 1031:204-13.
    View in: PubMed
    Score: 0.029
  29. Protein kinase Cbeta isoform inhibitors: a new treatment for diabetic cardiovascular diseases. Circulation. 2004 Jul 06; 110(1):7-9.
    View in: PubMed
    Score: 0.028
  30. The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance. J Clin Invest. 2003 May; 111(9):1373-80.
    View in: PubMed
    Score: 0.026
  31. Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation. Diabetes. 2003 Mar; 52(3):829-37.
    View in: PubMed
    Score: 0.025
  32. Vascular dysfunction in diabetes mellitus. Lancet. 1997 Jul; 350 Suppl 1:SI9-13.
    View in: PubMed
    Score: 0.017
  33. The role of hyperglycaemia and hyperinsulinaemia in causing vascular dysfunction in diabetes. Ann Med. 1996 Oct; 28(5):427-32.
    View in: PubMed
    Score: 0.016
  34. Associations between metabolic dysregulation and circulating biomarkers of fibrosis: the Cardiovascular Health Study. Metabolism. 2015 Oct; 64(10):1316-23.
    View in: PubMed
    Score: 0.015
  35. Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells. J Neurosci. 2005 Feb 02; 25(5):1240-8.
    View in: PubMed
    Score: 0.007
  36. Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group II: pathogenesis of atherosclerosis in diabetes. Circulation. 2002 May 07; 105(18):e138-43.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.