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George Liang King, M.D.

Concepts

This page shows the publications George King has written about Glucose.
Connection Strength

2.203
  1. Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy. Diabetes Care. 2019 07; 42(7):1263-1273.
    View in: PubMed
    Score: 0.339
  2. Preservation of renal function in chronic diabetes by enhancing glomerular glucose metabolism. J Mol Med (Berl). 2018 05; 96(5):373-381.
    View in: PubMed
    Score: 0.314
  3. Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction. Nat Med. 2017 Jun; 23(6):753-762.
    View in: PubMed
    Score: 0.294
  4. More sugar, less blood vessels: another piece in the puzzle of increased cardiovascular risk in diabetes. Arterioscler Thromb Vasc Biol. 2008 Apr; 28(4):608-10.
    View in: PubMed
    Score: 0.157
  5. Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation. Diabetes. 2000 Jul; 49(7):1239-48.
    View in: PubMed
    Score: 0.092
  6. d-Alpha-tocopherol prevents the hyperglycemia induced activation of diacylglycerol (DAG)-protein kinase C (PKC) pathway in vascular smooth muscle cell by an increase of DAG kinase activity. Diabetes Res Clin Pract. 1999 Sep; 45(2-3):183-90.
    View in: PubMed
    Score: 0.087
  7. Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways. J Clin Invest. 1999 Jan; 103(2):185-95.
    View in: PubMed
    Score: 0.083
  8. Vascular dysfunction in diabetes mellitus. Lancet. 1997 Jul; 350 Suppl 1:SI9-13.
    View in: PubMed
    Score: 0.075
  9. Role of protein kinase C in glucose- and angiotensin II-induced plasminogen activator inhibitor expression. Contrib Nephrol. 1996; 118:180-7.
    View in: PubMed
    Score: 0.067
  10. Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2. J Clin Invest. 1995 Aug; 96(2):733-40.
    View in: PubMed
    Score: 0.065
  11. Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues. Am J Physiol. 1994 Sep; 267(3 Pt 1):E369-79.
    View in: PubMed
    Score: 0.061
  12. Identification of multiple genes in bovine retinal pericytes altered by exposure to elevated levels of glucose by using mRNA differential display. Proc Natl Acad Sci U S A. 1994 Jun 21; 91(13):6231-5.
    View in: PubMed
    Score: 0.060
  13. Glucose induced genes in bovine aortic smooth muscle cells identified by mRNA differential display. FASEB J. 1994 Jan; 8(1):103-6.
    View in: PubMed
    Score: 0.059
  14. Differential regulation of glucose transport and transporters by glucose in vascular endothelial and smooth muscle cells. Diabetes. 1993 Jan; 42(1):80-9.
    View in: PubMed
    Score: 0.055
  15. Induction of resistance to endothelin-1's biochemical actions by elevated glucose levels in retinal pericytes. Diabetes. 1992 Dec; 41(12):1533-9.
    View in: PubMed
    Score: 0.054
  16. Glomerular VEGF resistance induced by PKCd/SHP-1 activation and contribution to diabetic nephropathy. FASEB J. 2012 Jul; 26(7):2963-74.
    View in: PubMed
    Score: 0.052
  17. Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy. Nat Med. 2009 Nov; 15(11):1298-306.
    View in: PubMed
    Score: 0.044
  18. Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications. Proc Natl Acad Sci U S A. 1989 07; 86(13):5141-5.
    View in: PubMed
    Score: 0.043
  19. Differential regulation of protein kinase C and (Na,K)-adenosine triphosphatase activities by elevated glucose levels in retinal capillary endothelial cells. J Clin Invest. 1989 Jan; 83(1):90-4.
    View in: PubMed
    Score: 0.041
  20. Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cells. J Biol Chem. 2002 Feb 01; 277(5):3680-5.
    View in: PubMed
    Score: 0.025
  21. Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats. J Clin Invest. 1997 Jul 01; 100(1):115-26.
    View in: PubMed
    Score: 0.019
  22. Vitamin E normalizes diacylglycerol-protein kinase C activation induced by hyperglycemia in rat vascular tissues. Diabetes. 1996 Jul; 45 Suppl 3:S117-9.
    View in: PubMed
    Score: 0.017
  23. Normalization of diacylglycerol-protein kinase C activation by vitamin E in aorta of diabetic rats and cultured rat smooth muscle cells exposed to elevated glucose levels. Diabetes. 1994 Nov; 43(11):1372-7.
    View in: PubMed
    Score: 0.016
  24. Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia. Diabetes. 1994 Sep; 43(9):1122-9.
    View in: PubMed
    Score: 0.015
  25. Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):11059-63.
    View in: PubMed
    Score: 0.014
  26. p38 MAPK is a major regulator of MafA protein stability under oxidative stress. Mol Endocrinol. 2009 Aug; 23(8):1281-90.
    View in: PubMed
    Score: 0.011
  27. Receptors for and effects of insulin and IGF-I in rat glomerular mesangial cells. Am J Physiol. 1988 Mar; 254(3 Pt 1):C411-6.
    View in: PubMed
    Score: 0.010
  28. Cell biology as an approach to the study of the vascular complications of diabetes. Metabolism. 1985 Dec; 34(12 Suppl 1):17-22.
    View in: PubMed
    Score: 0.008
  29. The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance. J Clin Invest. 2003 May; 111(9):1373-80.
    View in: PubMed
    Score: 0.007
  30. Differential responsiveness to insulin of endothelial and support cells from micro- and macrovessels. J Clin Invest. 1983 Apr; 71(4):974-9.
    View in: PubMed
    Score: 0.007
  31. Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group II: pathogenesis of atherosclerosis in diabetes. Circulation. 2002 May 07; 105(18):e138-43.
    View in: PubMed
    Score: 0.007
  32. Non-parallel evolution of metabolic and growth-promoting functions of insulin. Nature. 1981 Aug 13; 292(5824):644-6.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.