Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Mitzi Kuroda, Ph.D.

Other Positions

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R35GM126944 (KURODA, MITZI I) May 1, 2018 - Apr 30, 2023
    Epigenetic regulation of transcriptional programming
    Role: Principal Investigator
  2. R01GM101958 (KURODA, MITZI I) Apr 13, 2012 - Dec 31, 2019
    Comprehensive analysis of epigenetic regulators in their native chromatin context
    Role: Principal Investigator
  3. R03TW005669 (KURODA, MITZI) Sep 1, 2001 - Aug 31, 2004
    Molecular Genetics of Dosage Compensation in Drosophila
    Role: Principal Investigator
  4. R01GM045744 (KURODA, MITZI I) Apr 1, 1991 - Jun 30, 2018
    Molecular Genetics of Dosage Compensation in Drosophila
    Role: Principal Investigator
  5. R37GM045744 (KURODA, MITZI) Apr 1, 1991 - Mar 31, 2014
    Molecular Genetics of Dosage Compensation in Drosophila
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kang H, Cabrera JR, Zee BM, Kang HA, Jobe JM, Hegarty MB, Barry AE, Glotov A, Schwartz YB, Kuroda MI. Variant Polycomb complexes in Drosophila consistent with ancient functional diversity. Sci Adv. 2022 Sep 09; 8(36):eadd0103. PMID: 36070387; PMCID: PMC9451159.
    Citations: 3     Fields:    
  2. Naxerova K, Di Stefano B, Makofske JL, Watson EV, de Kort MA, Martin TD, Dezfulian M, Ricken D, Wooten EC, Kuroda MI, Hochedlinger K, Elledge SJ. Integrated loss- and gain-of-function screens define a core network governing human embryonic stem cell behavior. Genes Dev. 2021 11 01; 35(21-22):1527-1547. PMID: 34711655; PMCID: PMC8559676.
    Citations: 2     Fields:    Translation:HumansCells
  3. Shiota H, Alekseyenko AA, Wang ZA, Filic I, Knox TM, Luong NM, Huang Y, Scott DA, Jones KL, Gokhale PC, Lemieux ME, Cole PA, Kuroda MI, French CA. Chemical Screen Identifies Diverse and Novel Histone Deacetylase Inhibitors as Repressors of NUT Function: Implications for NUT Carcinoma Pathogenesis and Treatment. Mol Cancer Res. 2021 11; 19(11):1818-1830. PMID: 34285087; PMCID: PMC8568634.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  4. Kuroda MI, Kang H, De S, Kassis JA. Dynamic Competition of Polycomb and Trithorax in Transcriptional Programming. Annu Rev Biochem. 2020 06 20; 89:235-253. PMID: 31928411.
    Citations: 31     Fields:    Translation:AnimalsCells
  5. Zucconi BE, Makofske JL, Meyers DJ, Hwang Y, Wu M, Kuroda MI, Cole PA. Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP. Biochemistry. 2019 04 23; 58(16):2133-2143. PMID: 30924641; PMCID: PMC6948846.
    Citations: 11     Fields:    Translation:HumansCells
  6. Copur Ö, Gorchakov A, Finkl K, Kuroda MI, Müller J. Sex-specific phenotypes of histone H4 point mutants establish dosage compensation as the critical function of H4K16 acetylation in Drosophila. Proc Natl Acad Sci U S A. 2018 12 26; 115(52):13336-13341. PMID: 30530664; PMCID: PMC6310812.
    Citations: 15     Fields:    Translation:AnimalsCells
  7. Shiota H, Elya JE, Alekseyenko AA, Chou PM, Gorman SA, Barbash O, Becht K, Danga K, Kuroda MI, Nardi V, French CA. "Z4" Complex Member Fusions in NUT Carcinoma: Implications for a Novel Oncogenic Mechanism. Mol Cancer Res. 2018 12; 16(12):1826-1833. PMID: 30139738; PMCID: PMC6279489.
    Citations: 15     Fields:    Translation:HumansCells
  8. Kang H, Jung YL, McElroy KA, Zee BM, Wallace HA, Woolnough JL, Park PJ, Kuroda MI. Bivalent complexes of PRC1 with orthologs of BRD4 and MOZ/MORF target developmental genes in Drosophila. Genes Dev. 2017 10 01; 31(19):1988-2002. PMID: 29070704; PMCID: PMC5710143.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  9. Alekseyenko AA, Walsh EM, Zee BM, Pakozdi T, Hsi P, Lemieux ME, Dal Cin P, Ince TA, Kharchenko PV, Kuroda MI, French CA. Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma. Proc Natl Acad Sci U S A. 2017 05 23; 114(21):E4184-E4192. PMID: 28484033; PMCID: PMC5448232.
    Citations: 39     Fields:    Translation:HumansCells
  10. McElroy KA, Jung YL, Zee BM, Wang CI, Park PJ, Kuroda MI. upSET, the Drosophila homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks. G3 (Bethesda). 2017 02 09; 7(2):625-635. PMID: 28064188; PMCID: PMC5295607.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  11. Zee BM, Dibona AB, Alekseyenko AA, French CA, Kuroda MI. The Oncoprotein BRD4-NUT Generates Aberrant Histone Modification Patterns. PLoS One. 2016; 11(10):e0163820. PMID: 27698495.
    Citations: 7     Fields:    Translation:HumansCells
  12. Kuroda MI, Hilfiker A, Lucchesi JC. Dosage Compensation in Drosophila-a Model for the Coordinate Regulation of Transcription. Genetics. 2016 Oct; 204(2):435-450. PMID: 27729494.
    Citations: 36     Fields:    Translation:AnimalsCells
  13. Zee BM, Alekseyenko AA, McElroy KA, Kuroda MI. Streamlined discovery of cross-linked chromatin complexes and associated histone modifications by mass spectrometry. Proc Natl Acad Sci U S A. 2016 Feb 16; 113(7):1784-9. PMID: 26831069; PMCID: PMC4763777.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  14. Alekseyenko AA, Walsh EM, Wang X, Grayson AR, Hsi PT, Kharchenko PV, Kuroda MI, French CA. The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains. Genes Dev. 2015 Jul 15; 29(14):1507-23. PMID: 26220994; PMCID: PMC4526735.
    Citations: 69     Fields:    Translation:HumansCells
  15. Kang H, McElroy KA, Jung YL, Alekseyenko AA, Zee BM, Park PJ, Kuroda MI. Sex comb on midleg (Scm) is a functional link between PcG-repressive complexes in Drosophila. Genes Dev. 2015 Jun 01; 29(11):1136-50. PMID: 26063573; PMCID: PMC4470282.
    Citations: 32     Fields:    Translation:AnimalsCells
  16. Lucchesi JC, Kuroda MI. Dosage compensation in Drosophila. Cold Spring Harb Perspect Biol. 2015 May 01; 7(5). PMID: 25934013.
    Citations: 84     Fields:    Translation:AnimalsCells
  17. Alekseyenko AA, McElroy KA, Kang H, Zee BM, Kharchenko PV, Kuroda MI. BioTAP-XL: Cross-linking/Tandem Affinity Purification to Study DNA Targets, RNA, and Protein Components of Chromatin-Associated Complexes. Curr Protoc Mol Biol. 2015 Jan 05; 109:21.30.1-21.30.32. PMID: 25559106.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  18. Jung YL, Kang H, Park PJ, Kuroda MI. Correspondence of Drosophila polycomb group proteins with broad H3K27me3 silent domains. Fly (Austin). 2015; 9(4):178-82. PMID: 26940990.
    Citations: 1     Fields:    Translation:AnimalsCells
  19. Ho JW, Jung YL, Liu T, Alver BH, Lee S, Ikegami K, Sohn KA, Minoda A, Tolstorukov MY, Appert A, Parker SC, Gu T, Kundaje A, Riddle NC, Bishop E, Egelhofer TA, Hu SS, Alekseyenko AA, Rechtsteiner A, Asker D, Belsky JA, Bowman SK, Chen QB, Chen RA, Day DS, Dong Y, Dose AC, Duan X, Epstein CB, Ercan S, Feingold EA, Ferrari F, Garrigues JM, Gehlenborg N, Good PJ, Haseley P, He D, Herrmann M, Hoffman MM, Jeffers TE, Kharchenko PV, Kolasinska-Zwierz P, Kotwaliwale CV, Kumar N, Langley SA, Larschan EN, Latorre I, Libbrecht MW, Lin X, Park R, Pazin MJ, Pham HN, Plachetka A, Qin B, Schwartz YB, Shoresh N, Stempor P, Vielle A, Wang C, Whittle CM, Xue H, Kingston RE, Kim JH, Bernstein BE, Dernburg AF, Pirrotta V, Kuroda MI, Noble WS, Tullius TD, Kellis M, MacAlpine DM, Strome S, Elgin SC, Liu XS, Lieb JD, Ahringer J, Karpen GH, Park PJ. Comparative analysis of metazoan chromatin organization. Nature. 2014 Aug 28; 512(7515):449-52. PMID: 25164756.
    Citations: 182     Fields:    Translation:HumansAnimalsCells
  20. Alekseyenko AA, Gorchakov AA, Zee BM, Fuchs SM, Kharchenko PV, Kuroda MI. Heterochromatin-associated interactions of Drosophila HP1a with dADD1, HIPP1, and repetitive RNAs. Genes Dev. 2014 Jul 01; 28(13):1445-60. PMID: 24990964; PMCID: PMC4083088.
    Citations: 51     Fields:    Translation:AnimalsCells
  21. McElroy KA, Kang H, Kuroda MI. Are we there yet? Initial targeting of the Male-Specific Lethal and Polycomb group chromatin complexes in Drosophila. Open Biol. 2014 Mar 26; 4:140006. PMID: 24671948.
    Citations: 15     Fields:    Translation:AnimalsCells
  22. Jung YL, Luquette LJ, Ho JW, Ferrari F, Tolstorukov M, Minoda A, Issner R, Epstein CB, Karpen GH, Kuroda MI, Park PJ. Impact of sequencing depth in ChIP-seq experiments. Nucleic Acids Res. 2014 May; 42(9):e74. PMID: 24598259.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  23. Ferrari F, Alekseyenko AA, Park PJ, Kuroda MI. Transcriptional control of a whole chromosome: emerging models for dosage compensation. Nat Struct Mol Biol. 2014 Feb; 21(2):118-25. PMID: 24500429.
    Citations: 34     Fields:    Translation:AnimalsCells
  24. Alekseyenko AA, Gorchakov AA, Kharchenko PV, Kuroda MI. Reciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2488-93. PMID: 24550272; PMCID: PMC3932854.
    Citations: 47     Fields:    Translation:HumansCells
  25. Ferrari F, Plachetka A, Alekseyenko AA, Jung YL, Ozsolak F, Kharchenko PV, Park PJ, Kuroda MI. "Jump start and gain" model for dosage compensation in Drosophila based on direct sequencing of nascent transcripts. Cell Rep. 2013 Nov 14; 5(3):629-36. PMID: 24183666.
    Citations: 24     Fields:    Translation:AnimalsCells
  26. Alekseyenko AA, Ellison CE, Gorchakov AA, Zhou Q, Kaiser VB, Toda N, Walton Z, Peng S, Park PJ, Bachtrog D, Kuroda MI. Conservation and de novo acquisition of dosage compensation on newly evolved sex chromosomes in Drosophila. Genes Dev. 2013 Apr 15; 27(8):853-8. PMID: 23630075.
    Citations: 39     Fields:    Translation:AnimalsCells
  27. Wang CI, Alekseyenko AA, LeRoy G, Elia AE, Gorchakov AA, Britton LM, Elledge SJ, Kharchenko PV, Garcia BA, Kuroda MI. Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Nat Struct Mol Biol. 2013 Feb; 20(2):202-9. PMID: 23295261.
    Citations: 65     Fields:    Translation:AnimalsCells
  28. Riddle NC, Jung YL, Gu T, Alekseyenko AA, Asker D, Gui H, Kharchenko PV, Minoda A, Plachetka A, Schwartz YB, Tolstorukov MY, Kuroda MI, Pirrotta V, Karpen GH, Park PJ, Elgin SC. Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain. PLoS Genet. 2012 Sep; 8(9):e1002954. PMID: 23028361; PMCID: PMC3447959.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  29. Larschan E, Soruco MM, Lee OK, Peng S, Bishop E, Chery J, Goebel K, Feng J, Park PJ, Kuroda MI. Identification of chromatin-associated regulators of MSL complex targeting in Drosophila dosage compensation. PLoS Genet. 2012; 8(7):e1002830. PMID: 22844249.
    Citations: 32     Fields:    Translation:AnimalsCells
  30. Schwartz YB, Linder-Basso D, Kharchenko PV, Tolstorukov MY, Kim M, Li HB, Gorchakov AA, Minoda A, Shanower G, Alekseyenko AA, Riddle NC, Jung YL, Gu T, Plachetka A, Elgin SC, Kuroda MI, Park PJ, Savitsky M, Karpen GH, Pirrotta V. Nature and function of insulator protein binding sites in the Drosophila genome. Genome Res. 2012 Nov; 22(11):2188-98. PMID: 22767387.
    Citations: 111     Fields:    Translation:AnimalsCells
  31. Bateman JR, Larschan E, D'Souza R, Marshall LS, Dempsey KE, Johnson JE, Mellone BG, Kuroda MI. A genome-wide screen identifies genes that affect somatic homolog pairing in Drosophila. G3 (Bethesda). 2012 Jul; 2(7):731-40. PMID: 22870396.
    Citations: 26     Fields:    Translation:AnimalsCells
  32. Alekseyenko AA, Ho JW, Peng S, Gelbart M, Tolstorukov MY, Plachetka A, Kharchenko PV, Jung YL, Gorchakov AA, Larschan E, Gu T, Minoda A, Riddle NC, Schwartz YB, Elgin SC, Karpen GH, Pirrotta V, Kuroda MI, Park PJ. Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context. PLoS Genet. 2012; 8(4):e1002646. PMID: 22570616; PMCID: PMC3343056.
    Citations: 33     Fields:    Translation:AnimalsCells
  33. Simon MD, Wang CI, Kharchenko PV, West JA, Chapman BA, Alekseyenko AA, Borowsky ML, Kuroda MI, Kingston RE. The genomic binding sites of a noncoding RNA. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20497-502. PMID: 22143764.
    Citations: 231     Fields:    Translation:AnimalsCells
  34. Larschan E, Bishop EP, Kharchenko PV, Core LJ, Lis JT, Park PJ, Kuroda MI. X chromosome dosage compensation via enhanced transcriptional elongation in Drosophila. Nature. 2011 Mar 03; 471(7336):115-8. PMID: 21368835.
    Citations: 112     Fields:    Translation:AnimalsCells
  35. Strukov YG, Sural TH, Kuroda MI, Sedat JW. Evidence of activity-specific, radial organization of mitotic chromosomes in Drosophila. PLoS Biol. 2011 Jan 11; 9(1):e1000574. PMID: 21264350.
    Citations: 15     Fields:    Translation:AnimalsCells
  36. Riddle NC, Minoda A, Kharchenko PV, Alekseyenko AA, Schwartz YB, Tolstorukov MY, Gorchakov AA, Jaffe JD, Kennedy C, Linder-Basso D, Peach SE, Shanower G, Zheng H, Kuroda MI, Pirrotta V, Park PJ, Elgin SC, Karpen GH. Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin. Genome Res. 2011 Feb; 21(2):147-63. PMID: 21177972.
    Citations: 137     Fields:    Translation:HumansAnimalsCells
  37. Kharchenko PV, Alekseyenko AA, Schwartz YB, Minoda A, Riddle NC, Ernst J, Sabo PJ, Larschan E, Gorchakov AA, Gu T, Linder-Basso D, Plachetka A, Shanower G, Tolstorukov MY, Luquette LJ, Xi R, Jung YL, Park RW, Bishop EP, Canfield TK, Sandstrom R, Thurman RE, MacAlpine DM, Stamatoyannopoulos JA, Kellis M, Elgin SC, Kuroda MI, Pirrotta V, Karpen GH, Park PJ. Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. Nature. 2011 Mar 24; 471(7339):480-5. PMID: 21179089.
    Citations: 489     Fields:    Translation:AnimalsCells
  38. Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, Robine N, Washington NL, Di Stefano L, Berezikov E, Brown CD, Candeias R, Carlson JW, Carr A, Jungreis I, Marbach D, Sealfon R, Tolstorukov MY, Will S, Alekseyenko AA, Artieri C, Booth BW, Brooks AN, Dai Q, Davis CA, Duff MO, Feng X, Gorchakov AA, Gu T, Henikoff JG, Kapranov P, Li R, MacAlpine HK, Malone J, Minoda A, Nordman J, Okamura K, Perry M, Powell SK, Riddle NC, Sakai A, Samsonova A, Sandler JE, Schwartz YB, Sher N, Spokony R, Sturgill D, van Baren M, Wan KH, Yang L, Yu C, Feingold E, Good P, Guyer M, Lowdon R, Ahmad K, Andrews J, Berger B, Brenner SE, Brent MR, Cherbas L, Elgin SC, Gingeras TR, Grossman R, Hoskins RA, Kaufman TC, Kent W, Kuroda MI, Orr-Weaver T, Perrimon N, Pirrotta V, Posakony JW, Ren B, Russell S, Cherbas P, Graveley BR, Lewis S, Micklem G, Oliver B, Park PJ, Celniker SE, Henikoff S, Karpen GH, Lai EC, MacAlpine DM, Stein LD, White KP, Kellis M. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science. 2010 Dec 24; 330(6012):1787-97. PMID: 21177974.
    Citations: 664     Fields:    Translation:AnimalsCells
  39. Egelhofer TA, Minoda A, Klugman S, Lee K, Kolasinska-Zwierz P, Alekseyenko AA, Cheung MS, Day DS, Gadel S, Gorchakov AA, Gu T, Kharchenko PV, Kuan S, Latorre I, Linder-Basso D, Luu Y, Ngo Q, Perry M, Rechtsteiner A, Riddle NC, Schwartz YB, Shanower GA, Vielle A, Ahringer J, Elgin SC, Kuroda MI, Pirrotta V, Ren B, Strome S, Park PJ, Karpen GH, Hawkins RD, Lieb JD. An assessment of histone-modification antibody quality. Nat Struct Mol Biol. 2011 Jan; 18(1):91-3. PMID: 21131980.
    Citations: 209     Fields:    Translation:AnimalsCells
  40. Peng S, Kuroda MI, Park PJ. Quantized correlation coefficient for measuring reproducibility of ChIP-chip data. BMC Bioinformatics. 2010 Jul 27; 11:399. PMID: 20663215.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  41. Gorchakov AA, Alekseyenko AA, Kharchenko P, Park PJ, Kuroda MI. Long-range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X. Genes Dev. 2009 Oct 01; 23(19):2266-71. PMID: 19797766.
    Citations: 30     Fields:    Translation:AnimalsCells
  42. Gelbart ME, Larschan E, Peng S, Park PJ, Kuroda MI. Drosophila MSL complex globally acetylates H4K16 on the male X chromosome for dosage compensation. Nat Struct Mol Biol. 2009 Aug; 16(8):825-32. PMID: 19648925.
    Citations: 74     Fields:    Translation:AnimalsCells
  43. Gelbart ME, Kuroda MI. Drosophila dosage compensation: a complex voyage to the X chromosome. Development. 2009 May; 136(9):1399-410. PMID: 19363150.
    Citations: 137     Fields:    Translation:AnimalsCells
  44. Sural TH, Peng S, Li B, Workman JL, Park PJ, Kuroda MI. The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila melanogaster X chromosome. Nat Struct Mol Biol. 2008 Dec; 15(12):1318-25. PMID: 19029895.
    Citations: 58     Fields:    Translation:AnimalsCells
  45. Alekseyenko AA, Peng S, Larschan E, Gorchakov AA, Lee OK, Kharchenko P, McGrath SD, Wang CI, Mardis ER, Park PJ, Kuroda MI. A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome. Cell. 2008 Aug 22; 134(4):599-609. PMID: 18724933.
    Citations: 157     Fields:    Translation:AnimalsCells
  46. Park SW, Kuroda MI, Park Y. Regulation of histone H4 Lys16 acetylation by predicted alternative secondary structures in roX noncoding RNAs. Mol Cell Biol. 2008 Aug; 28(16):4952-62. PMID: 18541664.
    Citations: 20     Fields:    Translation:AnimalsCells
  47. Larschan E, Alekseyenko AA, Gortchakov AA, Peng S, Li B, Yang P, Workman JL, Park PJ, Kuroda MI. MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism. Mol Cell. 2007 Oct 12; 28(1):121-33. PMID: 17936709.
    Citations: 133     Fields:    Translation:AnimalsCells
  48. Peng S, Alekseyenko AA, Larschan E, Kuroda MI, Park PJ. Normalization and experimental design for ChIP-chip data. BMC Bioinformatics. 2007 Jun 25; 8:219. PMID: 17592629.
    Citations: 31     Fields:    
  49. Bai X, Larschan E, Kwon SY, Badenhorst P, Kuroda MI. Regional control of chromatin organization by noncoding roX RNAs and the NURF remodeling complex in Drosophila melanogaster. Genetics. 2007 Jul; 176(3):1491-9. PMID: 17507677; PMCID: PMC1931522.
    Citations: 27     Fields:    Translation:AnimalsCells
  50. Yang PK, Kuroda MI. Noncoding RNAs and intranuclear positioning in monoallelic gene expression. Cell. 2007 Feb 23; 128(4):777-86. PMID: 17320513.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  51. Alekseyenko AA, Larschan E, Lai WR, Park PJ, Kuroda MI. High-resolution ChIP-chip analysis reveals that the Drosophila MSL complex selectively identifies active genes on the male X chromosome. Genes Dev. 2006 Apr 01; 20(7):848-57. PMID: 16547173; PMCID: PMC1472287.
    Citations: 138     Fields:    Translation:AnimalsCells
  52. Larschan E, Alekseyenko AA, Lai WR, Park PJ, Kuroda MI. MSL complex associates with clusters of actively transcribed genes along the Drosophila male X chromosome. Cold Spring Harb Symp Quant Biol. 2006; 71:385-94. PMID: 17381321.
    Citations: 3     Fields:    Translation:AnimalsCells
  53. Park Y, Oh H, Meller VH, Kuroda MI. Variable splicing of non-coding roX2 RNAs influences targeting of MSL dosage compensation complexes in Drosophila. RNA Biol. 2005 Oct-Dec; 2(4):157-64. PMID: 17114930.
    Citations: 11     Fields:    Translation:AnimalsCells
  54. Hamada FN, Park PJ, Gordadze PR, Kuroda MI. Global regulation of X chromosomal genes by the MSL complex in Drosophila melanogaster. Genes Dev. 2005 Oct 01; 19(19):2289-94. PMID: 16204180; PMCID: PMC1240037.
    Citations: 101     Fields:    Translation:AnimalsCells
  55. Bai X, Alekseyenko AA, Kuroda MI. Sequence-specific targeting of MSL complex regulates transcription of the roX RNA genes. EMBO J. 2004 Jul 21; 23(14):2853-61. PMID: 15229655; PMCID: PMC514957.
    Citations: 32     Fields:    Translation:AnimalsCells
  56. Oh H, Bone JR, Kuroda MI. Multiple classes of MSL binding sites target dosage compensation to the X chromosome of Drosophila. Curr Biol. 2004 Mar 23; 14(6):481-7. PMID: 15043812.
    Citations: 45     Fields:    Translation:AnimalsCells
  57. Alekseyenko AA, Kuroda MI. Molecular biology. Filling gaps in genome organization. Science. 2004 Feb 20; 303(5661):1148-9. PMID: 14976302.
    Citations: 2     Fields:    Translation:AnimalsCells
  58. Oh H, Bai X, Park Y, Bone JR, Kuroda MI. Targeting dosage compensation to the X chromosome of Drosophila males. Cold Spring Harb Symp Quant Biol. 2004; 69:81-8. PMID: 16117636.
    Citations: 6     Fields:    Translation:AnimalsCells
  59. Demakova OV, Kotlikova IV, Gordadze PR, Alekseyenko AA, Kuroda MI, Zhimulev IF. The MSL complex levels are critical for its correct targeting to the chromosomes in Drosophila melanogaster. Chromosoma. 2003 Oct; 112(3):103-15. PMID: 14579126.
    Citations: 40     Fields:    Translation:AnimalsCells
  60. Stuckenholz C, Meller VH, Kuroda MI. Functional redundancy within roX1, a noncoding RNA involved in dosage compensation in Drosophila melanogaster. Genetics. 2003 Jul; 164(3):1003-14. PMID: 12871910.
    Citations: 27     Fields:    Translation:AnimalsCells
  61. Kelley RL, Kuroda MI. The Drosophila roX1 RNA gene can overcome silent chromatin by recruiting the male-specific lethal dosage compensation complex. Genetics. 2003 Jun; 164(2):565-74. PMID: 12807777.
    Citations: 19     Fields:    Translation:AnimalsCells
  62. Oh H, Park Y, Kuroda MI. Local spreading of MSL complexes from roX genes on the Drosophila X chromosome. Genes Dev. 2003 Jun 01; 17(11):1334-9. PMID: 12782651; PMCID: PMC196065.
    Citations: 55     Fields:    Translation:AnimalsCells
  63. Park Y, Mengus G, Bai X, Kageyama Y, Meller VH, Becker PB, Kuroda MI. Sequence-specific targeting of Drosophila roX genes by the MSL dosage compensation complex. Mol Cell. 2003 Apr; 11(4):977-86. PMID: 12718883.
    Citations: 42     Fields:    Translation:AnimalsCells
  64. Park Y, Kelley RL, Oh H, Kuroda MI, Meller VH. Extent of chromatin spreading determined by roX RNA recruitment of MSL proteins. Science. 2002 Nov 22; 298(5598):1620-3. PMID: 12446910.
    Citations: 68     Fields:    Translation:AnimalsCells
  65. Meller VH, Kuroda MI. Sex and the single chromosome. Adv Genet. 2002; 46:1-24. PMID: 11931222.
    Citations: 19     Fields:    Translation:AnimalsCells
  66. Park Y, Kuroda MI. Epigenetic aspects of X-chromosome dosage compensation. Science. 2001 Aug 10; 293(5532):1083-5. PMID: 11498577.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  67. Kageyama Y, Mengus G, Gilfillan G, Kennedy HG, Stuckenholz C, Kelley RL, Becker PB, Kuroda MI. Association and spreading of the Drosophila dosage compensation complex from a discrete roX1 chromatin entry site. EMBO J. 2001 May 01; 20(9):2236-45. PMID: 11331589; PMCID: PMC125240.
    Citations: 49     Fields:    Translation:AnimalsCells
  68. Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, Hayward DC, Ball EE, Degnan B, Müller P, Spring J, Srinivasan A, Fishman M, Finnerty J, Corbo J, Levine M, Leahy P, Davidson E, Ruvkun G. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature. 2000 Nov 02; 408(6808):86-9. PMID: 11081512.
    Citations: 815     Fields:    Translation:HumansAnimalsCells
  69. Kelley RL, Kuroda MI. The role of chromosomal RNAs in marking the X for dosage compensation. Curr Opin Genet Dev. 2000 Oct; 10(5):555-61. PMID: 10980435.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  70. Kelley RL, Kuroda MI. Noncoding RNA genes in dosage compensation and imprinting. Cell. 2000 Sep 29; 103(1):9-12. PMID: 11051542.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  71. Meller VH, Gordadze PR, Park Y, Chu X, Stuckenholz C, Kelley RL, Kuroda MI. Ordered assembly of roX RNAs into MSL complexes on the dosage-compensated X chromosome in Drosophila. Curr Biol. 2000 Feb 10; 10(3):136-43. PMID: 10679323.
    Citations: 69     Fields:    Translation:AnimalsCells
  72. Stuckenholz C, Kageyama Y, Kuroda MI. Guilt by association: non-coding RNAs, chromosome-specific proteins and dosage compensation in Drosophila. Trends Genet. 1999 Nov; 15(11):454-8. PMID: 10529808.
    Citations: 19     Fields:    Translation:AnimalsCells
  73. Kelley RL, Meller VH, Gordadze PR, Roman G, Davis RL, Kuroda MI. Epigenetic spreading of the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin. Cell. 1999 Aug 20; 98(4):513-22. PMID: 10481915.
    Citations: 144     Fields:    Translation:AnimalsCells
  74. Kuroda MI, Kelley RL. Sex and repression. Science. 1999 Jun 11; 284(5421):1787-8. PMID: 10391797.
    Citations:    Fields:    Translation:AnimalsCells
  75. Chang KA, Kuroda MI. Modulation of MSL1 abundance in female Drosophila contributes to the sex specificity of dosage compensation. Genetics. 1998 Oct; 150(2):699-709. PMID: 9755201.
    Citations: 20     Fields:    Translation:AnimalsCells
  76. Copps K, Richman R, Lyman LM, Chang KA, Rampersad-Ammons J, Kuroda MI. Complex formation by the Drosophila MSL proteins: role of the MSL2 RING finger in protein complex assembly. EMBO J. 1998 Sep 15; 17(18):5409-17. PMID: 9736618; PMCID: PMC1170866.
    Citations: 57     Fields:    Translation:AnimalsCells
  77. Rastelli L, Kuroda MI. An analysis of maleless and histone H4 acetylation in Drosophila melanogaster spermatogenesis. Mech Dev. 1998 Feb; 71(1-2):107-17. PMID: 9507080.
    Citations: 45     Fields:    Translation:AnimalsCells
  78. Lyman LM, Copps K, Rastelli L, Kelley RL, Kuroda MI. Drosophila male-specific lethal-2 protein: structure/function analysis and dependence on MSL-1 for chromosome association. Genetics. 1997 Dec; 147(4):1743-53. PMID: 9409833.
    Citations: 72     Fields:    Translation:AnimalsCells
  79. Kuroda MI, Meller VH. Transient Xist-ence. Cell. 1997 Oct 03; 91(1):9-11. PMID: 9335329.
    Citations: 1     Fields:    Translation:Animals
  80. Lee CG, Chang KA, Kuroda MI, Hurwitz J. The NTPase/helicase activities of Drosophila maleless, an essential factor in dosage compensation. EMBO J. 1997 May 15; 16(10):2671-81. PMID: 9184214; PMCID: PMC1169878.
    Citations: 50     Fields:    Translation:AnimalsCells
  81. Kelley RL, Wang J, Bell L, Kuroda MI. Sex lethal controls dosage compensation in Drosophila by a non-splicing mechanism. Nature. 1997 May 08; 387(6629):195-9. PMID: 9144292.
    Citations: 111     Fields:    Translation:AnimalsCells
  82. Meller VH, Wu KH, Roman G, Kuroda MI, Davis RL. roX1 RNA paints the X chromosome of male Drosophila and is regulated by the dosage compensation system. Cell. 1997 Feb 21; 88(4):445-57. PMID: 9038336.
    Citations: 115     Fields:    Translation:AnimalsCells
  83. Kuroda MI, Villeneuve AM. Promiscuous chromosomal proteins: complexes about sex. Science. 1996 Dec 06; 274(5293):1633-4. PMID: 8984631.
    Citations:    Fields:    Translation:AnimalsCells
  84. Bone JR, Kuroda MI. Dosage compensation regulatory proteins and the evolution of sex chromosomes in Drosophila. Genetics. 1996 Oct; 144(2):705-13. PMID: 8889531.
    Citations: 44     Fields:    Translation:AnimalsCells
  85. Richter L, Bone JR, Kuroda MI. RNA-dependent association of the Drosophila maleless protein with the male X chromosome. Genes Cells. 1996 Mar; 1(3):325-36. PMID: 9133666.
    Citations: 38     Fields:    Translation:AnimalsCells
  86. Kelley RL, Kuroda MI. Equality for X chromosomes. Science. 1995 Dec 08; 270(5242):1607-10. PMID: 7502070.
    Citations: 30     Fields:    Translation:AnimalsCells
  87. Rastelli L, Richman R, Kuroda MI. The dosage compensation regulators MLE, MSL-1 and MSL-2 are interdependent since early embryogenesis in Drosophila. Mech Dev. 1995 Oct; 53(2):223-33. PMID: 8562424.
    Citations: 36     Fields:    Translation:AnimalsCells
  88. Kelley RL, Solovyeva I, Lyman LM, Richman R, Solovyev V, Kuroda MI. Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila. Cell. 1995 Jun 16; 81(6):867-77. PMID: 7781064.
    Citations: 140     Fields:    Translation:AnimalsCells
  89. Lavender JS, Birley AJ, Palmer MJ, Kuroda MI, Turner BM. Histone H4 acetylated at lysine 16 and proteins of the Drosophila dosage compensation pathway co-localize on the male X chromosome through mitosis. Chromosome Res. 1994 Sep; 2(5):398-404. PMID: 7981944.
    Citations: 12     Fields:    Translation:AnimalsCells
  90. Palmer MJ, Richman R, Richter L, Kuroda MI. Sex-specific regulation of the male-specific lethal-1 dosage compensation gene in Drosophila. Genes Dev. 1994 Mar 15; 8(6):698-706. PMID: 7926760.
    Citations: 37     Fields:    Translation:Animals
  91. Bone JR, Lavender J, Richman R, Palmer MJ, Turner BM, Kuroda MI. Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila. Genes Dev. 1994 Jan; 8(1):96-104. PMID: 8288132.
    Citations: 114     Fields:    Translation:AnimalsCells
  92. Palmer MJ, Mergner VA, Richman R, Manning JE, Kuroda MI, Lucchesi JC. The male-specific lethal-one (msl-1) gene of Drosophila melanogaster encodes a novel protein that associates with the X chromosome in males. Genetics. 1993 Jun; 134(2):545-57. PMID: 8325488.
    Citations: 36     Fields:    Translation:AnimalsCells
  93. Gorman M, Kuroda MI, Baker BS. Regulation of the sex-specific binding of the maleless dosage compensation protein to the male X chromosome in Drosophila. Cell. 1993 Jan 15; 72(1):39-49. PMID: 8422681.
    Citations: 27     Fields:    Translation:AnimalsCells
  94. Kuroda, MI, Palmer MJ, Lucchesi JC. X chromosome dosage compensation in Drosophila. Seminars in Dev. Biol. 1993; 4:107-116.
  95. Kuroda MI, Kernan MJ, Kreber R, Ganetzky B, Baker BS. The maleless protein associates with the X chromosome to regulate dosage compensation in Drosophila. Cell. 1991 Sep 06; 66(5):935-47. PMID: 1653648.
    Citations: 105     Fields:    Translation:AnimalsCells
  96. Kernan MJ, Kuroda MI, Kreber R, Baker BS, Ganetzky B. napts, a mutation affecting sodium channel activity in Drosophila, is an allele of mle, a regulator of X chromosome transcription. Cell. 1991 Sep 06; 66(5):949-59. PMID: 1653649.
    Citations: 41     Fields:    Translation:AnimalsCells
  97. Gollnick P, Ishino S, Kuroda MI, Henner DJ, Yanofsky C. The mtr locus is a two-gene operon required for transcription attenuation in the trp operon of Bacillus subtilis. Proc Natl Acad Sci U S A. 1990 Nov; 87(22):8726-30. PMID: 2123343; PMCID: PMC55032.
    Citations: 42     Fields:    Translation:Cells
  98. Kuroda MI, Henner D, Yanofsky C. cis-acting sites in the transcript of the Bacillus subtilis trp operon regulate expression of the operon. J Bacteriol. 1988 Jul; 170(7):3080-8. PMID: 3133360; PMCID: PMC211252.
    Citations: 42     Fields:    Translation:Cells
  99. Kuroda MI, Shimotsu H, Henner DJ, Yanofsky C. Regulatory elements common to the Bacillus pumilus and Bacillus subtilis trp operons. J Bacteriol. 1986 Sep; 167(3):792-8. PMID: 3091579; PMCID: PMC215943.
    Citations: 14     Fields:    Translation:Cells
  100. Shimotsu H, Kuroda MI, Yanofsky C, Henner DJ. Novel form of transcription attenuation regulates expression the Bacillus subtilis tryptophan operon. J Bacteriol. 1986 May; 166(2):461-71. PMID: 2422155; PMCID: PMC214627.
    Citations: 64     Fields:    Translation:Cells
  101. Kuroda MI, Yanofsky C. Evidence for the transcript secondary structures predicted to regulate transcription attenuation in the trp operon. J Biol Chem. 1984 Oct 25; 259(20):12838-43. PMID: 6092347.
    Citations: 5     Fields:    Translation:Cells
  102. Kuroda MI, Yanofsky C. Correction of the nucleotide sequence of the Citrobacter freundii tryptophan operon regulatory region. J Bacteriol. 1984 Sep; 159(3):1063-4. PMID: 6090386.
    Citations: 2     Fields:    Translation:Cells
  103. Stroynowski I, Kuroda M, Yanofsky C. Transcription termination in vitro at the tryptophan operon attenuator is controlled by secondary structures in the leader transcript. Pro. Natl. Acad. Sci. USA. 1983; 80:2206-2210.
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