Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Ralph Mazitschek, Ph.D.

Co-Author

This page shows the publications co-authored by Ralph Mazitschek and Stephen Haggarty.
Connection Strength

1.526
  1. Activation of WNT and CREB signaling pathways in human neuronal cells in response to the Omega-3 fatty acid docosahexaenoic acid (DHA). Mol Cell Neurosci. 2019 09; 99:103386.
    View in: PubMed
    Score: 0.212
  2. Class I Histone Deacetylase Inhibition by Tianeptinaline Modulates Neuroplasticity and Enhances Memory. ACS Chem Neurosci. 2018 09 19; 9(9):2262-2273.
    View in: PubMed
    Score: 0.199
  3. Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia. Cell Chem Biol. 2017 Jul 20; 24(7):892-906.e5.
    View in: PubMed
    Score: 0.186
  4. Light-controlled modulation of gene expression by chemical optoepigenetic probes. Nat Chem Biol. 2016 May; 12(5):317-23.
    View in: PubMed
    Score: 0.170
  5. Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation. Bioorg Med Chem Lett. 2016 Feb 15; 26(4):1265-1271.
    View in: PubMed
    Score: 0.168
  6. Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity. Neuropharmacology. 2013 Jan; 64:81-96.
    View in: PubMed
    Score: 0.131
  7. Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin. ACS Med Chem Lett. 2010 Oct 08; 2(1):39-42.
    View in: PubMed
    Score: 0.116
  8. Chemical phylogenetics of histone deacetylases. Nat Chem Biol. 2010 Mar; 6(3):238-243.
    View in: PubMed
    Score: 0.111
  9. Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells. ACS Chem Biol. 2017 08 18; 12(8):2139-2148.
    View in: PubMed
    Score: 0.046
  10. HDAC6 inhibitors modulate Lys49 acetylation and membrane localization of ß-catenin in human iPSC-derived neuronal cells. ACS Chem Biol. 2015 Mar 20; 10(3):883-90.
    View in: PubMed
    Score: 0.039
  11. Histone deacetylase 3 as a novel therapeutic target in multiple myeloma. Leukemia. 2014 Mar; 28(3):680-9.
    View in: PubMed
    Score: 0.035
  12. Synapse microarray identification of small molecules that enhance synaptogenesis. Nat Commun. 2011 Oct 25; 2:510.
    View in: PubMed
    Score: 0.031
  13. Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease. Proc Natl Acad Sci U S A. 2010 Jul 13; 107(28):12617-22.
    View in: PubMed
    Score: 0.029
  14. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature. 2009 May 07; 459(7243):55-60.
    View in: PubMed
    Score: 0.026
  15. Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity. Neuron. 2008 Dec 10; 60(5):803-17.
    View in: PubMed
    Score: 0.026
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.