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Robert John Petrella, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Boa Sorte Silva NC, Nagamatsu LS, Gill DP, Owen AM, Petrella RJ. Memory Function and Brain Functional Connectivity Adaptations Following Multiple-Modality Exercise and Mind-Motor Training in Older Adults at Risk of Dementia: An Exploratory Sub-Study. Front Aging Neurosci. 2020; 12:22. PMID: 32158386.
  2. Boa Sorte Silva NC, Pulford RW, Lee DS, Petrella RJ. Heart failure management insights from primary care physicians and allied health care providers in Southwestern Ontario. BMC Fam Pract. 2020 01 13; 21(1):8. PMID: 31931728.
  3. Migliore A, Gigliucci G, Petrella RJ, Bannuru RR, Chevalier X, Maheu E, Raman R, Herrero-Beaumont G, Isailovic N, Matucci Cerinc M. It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis. Ther Clin Risk Manag. 2019; 15:1479-1482. PMID: 31920321.
  4. Migliore A, Gigliucci G, Alekseeva L, Avasthi S, Bannuru RR, Chevalier X, Conrozier T, Crimaldi S, Damjanov N, de Campos GC, Diracoglu D, Herrero-Beaumont G, Iolascon G, Ionescu R, Isailovic N, Jerosch J, Lains J, Maheu E, Makri S, Martusevich N, Matucci Cerinc M, Micu M, Pavelka K, Petrella RJ, Tarantino U, Raman R. Treat-to-target strategy for knee osteoarthritis. International technical expert panel consensus and good clinical practice statements. Ther Adv Musculoskelet Dis. 2019; 11:1759720X19893800. PMID: 31903099.
  5. Schulz JM, Birmingham TB, Atkinson HF, Woehrle E, Primeau CA, Lukacs MJ, Al-Khazraji BK, Khan MCM, Zomar BO, Petrella RJ, Beier F, Appleton CT, Shoemaker JK, Bryant DM. Are we missing the target? Are we aiming too low? What are the aerobic exercise prescriptions and their effects on markers of cardiovascular health and systemic inflammation in patients with knee osteoarthritis? A systematic review and meta-analysis. Br J Sports Med. 2019 Dec 17. PMID: 31848152.
  6. Tam J, Lacaille D, Liu-Ambrose T, Shaw C, Xie H, Backman CL, Esdaile JM, Miller K, Petrella R, Li LC. Effectiveness of an online self-management tool, OPERAS (an On-demand Program to EmpoweR Active Self-management), for people with rheumatoid arthritis: a research protocol. Trials. 2019 Dec 11; 20(1):712. PMID: 31829286.
  7. Gill DP, Blunt W, Boa Sorte Silva NC, Stiller-Moldovan C, Zou GY, Petrella RJ. The HealtheSteps™ lifestyle prescription program to improve physical activity and modifiable risk factors for chronic disease: a pragmatic randomized controlled trial. BMC Public Health. 2019 Jun 28; 19(1):841. PMID: 31253112.
  8. Ryan BL, Maddocks HL, McKay S, Petrella R, Terry AL, Stewart M. Identifying musculoskeletal conditions in electronic medical records: a prevalence and validation study using the Deliver Primary Healthcare Information (DELPHI) database. BMC Musculoskelet Disord. 2019 May 03; 20(1):187. PMID: 31053119.
  9. Karmali S, Ng V, Battram D, Burke S, Morrow D, Pearson ES, Tucker P, Mantler T, Cramp A, Petrella R, Irwin JD. Coaching and/or education intervention for parents with overweight/obesity and their children: study protocol of a single-centre randomized controlled trial. BMC Public Health. 2019 Mar 28; 19(1):345. PMID: 30922282.
  10. Shellington EM, Gill DP, Shigematsu R, Petrella RJ. Innovative Exercise as an Intervention for Older Adults with Knee Osteoarthritis: A Pilot Feasibility Study. Can J Aging. 2019 03; 38(1):111-121. PMID: 30404676.
    Citations:    Fields:    
  11. Gavarkovs AG, Blunt W, Petrella RJ. A protocol for designing online training to support the implementation of community-based interventions. Eval Program Plann. 2019 02; 72:77-87. PMID: 30316943.
    Citations:    Fields:    
  12. Brander V, Skrepnik N, Petrella RJ, Jiang GL, Accomando B, Vardanyan A. Evaluating the use of intra-articular injections as a treatment for painful hip osteoarthritis: a randomized, double-blind, multicenter, parallel-group study comparing a single 6-mL injection of hylan G-F 20 with saline. Osteoarthritis Cartilage. 2019 01; 27(1):59-70. PMID: 30223023.
    Citations:    Fields:    
  13. Shellington EM, Reichert SM, Petrella RJ. Commentary on: "Effects of Regular Physical Activity on the Cognitive Performance of Type 2 Diabetic Patients: A Systematic Review" by Podolski et al. (Metab Syndr Relat Disord 2017;15:481-493). Metab Syndr Relat Disord. 2018 08; 16(6):255-261. PMID: 29768089.
    Citations:    Fields:    
  14. Boa Sorte Silva NC, Gill DP, Owen AM, Liu-Ambrose T, Hachinski V, Shigematsu R, Petrella RJ. Cognitive changes following multiple-modality exercise and mind-motor training in older adults with subjective cognitive complaints: The M4 study. PLoS One. 2018; 13(4):e0196356. PMID: 29698440.
    Citations:    Fields:    Translation:Humans
  15. Boa Sorte Silva NC, Gregory MA, Gill DP, McGowan CL, Petrella RJ. The Impact of Blood Pressure Dipping Status on Cognition, Mobility, and Cardiovascular Health in Older Adults Following an Exercise Program. Gerontol Geriatr Med. 2018 Jan-Dec; 4:2333721418770333. PMID: 29761133.
  16. Shellington EM, Reichert SM, Heath M, Gill DP, Shigematsu R, Petrella RJ. Results From a Feasibility Study of Square-Stepping Exercise in Older Adults With Type 2 Diabetes and Self-Reported Cognitive Complaints to Improve Global Cognitive Functioning. Can J Diabetes. 2018 Dec; 42(6):603-612.e1. PMID: 29884522.
    Citations:    Fields:    
  17. Petrella, R.J. Optimization Bias in Energy-Based Structure Prediction. J. Theor Comput Chem. 2013; 12(8):1341014.
  18. Petrella RJ. A versatile method for systematic conformational searches: Application to CheY. J Comput Chem. 2011; 32(11):2369-2385.
  19. Brooks BR, Brooks CL, Mackerell AD, Nilsson L, Petrella RJ, Roux B, Won Y, Archontis G, Bartels C, Boresch S, Caflisch A, Caves L, Cui Q, Dinner AR, Feig M, Fischer S, Gao J, Hodoscek M, Im W, Kuczera K, Lazaridis T, Ma J, Ovchinnikov V, Paci E, Pastor RW, Post CB, Pu JZ, Schaefer M, Tidor B, Venable RM, Woodcock HL, Wu X, Yang W, York DM, Karplus M. CHARMM: the biomolecular simulation program. J Comput Chem. 2009 Jul 30; 30(10):1545-614. PMID: 19444816.
    Citations: 1510     Fields:    
  20. Komazin-Meredith G, Petrella RJ, Santos WL, Filman DJ, Hogle JM, Verdine GL, Karplus M, Coen DM. The human cytomegalovirus UL44 C clamp wraps around DNA. Structure. 2008 Aug 06; 16(8):1214-25. PMID: 18682223.
    Citations: 11     Fields:    Translation:HumansCells
  21. Petrella RJ, Karplus M. Electrostatic energies and forces computed without explicit interparticle interactions: a linear time complexity formulation. J Comput Chem. 2005 Jun; 26(8):755-87. PMID: 15800892.
    Citations:    Fields:    
  22. Petrella RJ, Karplus M. The role of carbon-donor hydrogen bonds in stabilizing tryptophan conformations. Proteins. 2004 Mar 01; 54(4):716-26. PMID: 14997567.
    Citations: 3     Fields:    Translation:Cells
  23. Petrella RJ, Andricioaei I, Brooks BR, Karplus M. An improved method for nonbonded list generation: rapid determination of near-neighbor pairs. J Comput Chem. 2003 Jan 30; 24(2):222-31. PMID: 12497601.
    Citations: 4     Fields:    
  24. Petrella RJ, Karplus M. The energetics of off-rotamer protein side-chain conformations. J Mol Biol. 2001 Oct 05; 312(5):1161-75. PMID: 11580256.
    Citations: 12     Fields:    Translation:Cells
  25. Petrella RJ, Lazaridis T, Karplus M. A Limiting-Case Study of Protein Structure Prediction: Energy-Based Searches of Reduced Conformational Space. J Phys Chem. 2000; 104:11370-11378.
  26. Petrella RJ, Lazaridis T, Karplus M. Protein sidechain conformer prediction: a test of the energy function. Fold Des. 1998; 3(5):353-77. PMID: 9806937.
    Citations: 11     Fields:    Translation:Cells
  27. Petrella RJ, Yokoyama MM. Ubihomologous homology usage. Nature. 1990 Feb 08; 343(6258):518. PMID: 2300203.
    Citations:    Fields:    
  28. Petrella RJ, Yokoyama MM. Enzyme-Inhibiting Antibodies and Immunoglobulin Combining Site Functional Perspectives. Kurume Med J. 1990; 37:209-238.
  29. Inoue M, Sei Y, Kashiwagi S, Shingu T, Yokoyama MM. Presence of HIV-1 Reverse Transcriptase Inhibitory Antibodies and Absence of Anti-HIV Neutralizing Antibodies in the Sera of Some HTLV-I Carriers. JPN J Clin Lab Immun. 1989; 28:173-177.
  30. Sei Y, Inoue M, Yokoyama MM, Petrella RJ. Immunity in AIDS. JPN J Immun. 1988; 20:389.
  31. Sei Y, Tsang PH, Petrella RJ, Bekesi JG. Multiple dysfunctions in developmental and activational stages of T lymphocytes, B lymphocytes and monocytes in ARC and AIDS patients. Immunol Lett. 1987 Nov; 16(2):157-62. PMID: 3501405.
    Citations: 1     Fields:    Translation:HumansCells
  32. Sei Y, Petrella RJ, Inoue M, Yokoyama MM, Bekesi JG. Prognostic Importance of Presence of NAb and Anti-p17/24 Antibodies in HIV Infected Individuals. Blood. 1987; 70:126a.
  33. Sei Y, Petrella RJ, Tsang P, Bekesi JG, Yokoyama MM. Monocytes in AIDS. N Engl J Med. 1986 Dec 18; 315(25):1611-2. PMID: 3466035.
    Citations: 7     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.