Harvard Catalyst Profiles

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Zhongcong Xie, Ph.D., M.D.

Concepts

This page shows the publications Zhongcong Xie has written about Isoflurane.
Connection Strength

8.503
  1. Sun Y, Zhang Y, Cheng B, Dong Y, Pan C, Li T, Xie Z. Glucose may attenuate isoflurane-induced caspase-3 activation in H4 human neuroglioma cells. Anesth Analg. 2014 Dec; 119(6):1373-80.
    View in: PubMed
    Score: 0.506
  2. Cheng B, Zhang Y, Wang A, Dong Y, Xie Z. Vitamin C Attenuates Isoflurane-Induced Caspase-3 Activation and Cognitive Impairment. Mol Neurobiol. 2015 Dec; 52(3):1580-1589.
    View in: PubMed
    Score: 0.503
  3. Xie Z. Cancer prognosis: can anesthesia play a role? Anesthesiology. 2013 Sep; 119(3):501-3.
    View in: PubMed
    Score: 0.464
  4. Dong Y, Wu X, Zhang G, Xu Z, Zhang Y, Gautam V, Kovacs DM, Wu A, Yue Y, Xie Z. Isoflurane facilitates synaptic NMDA receptor endocytosis in mice primary neurons. Curr Mol Med. 2013 May; 13(4):488-98.
    View in: PubMed
    Score: 0.453
  5. Zhang Y, Xie Z. Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory. Ann Neurol. 2012 Oct; 72(4):630.
    View in: PubMed
    Score: 0.435
  6. Dong Y, Wu X, Xu Z, Zhang Y, Xie Z. Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Aß generation. PLoS One. 2012; 7(6):e39386.
    View in: PubMed
    Score: 0.427
  7. Zhang Y, Xu Z, Wang H, Dong Y, Shi HN, Culley DJ, Crosby G, Marcantonio ER, Tanzi RE, Xie Z. Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory. Ann Neurol. 2012 May; 71(5):687-98.
    View in: PubMed
    Score: 0.418
  8. Zhang B, Tian M, Zhen Y, Yue Y, Sherman J, Zheng H, Li S, Tanzi RE, Marcantonio ER, Xie Z. The effects of isoflurane and desflurane on cognitive function in humans. Anesth Analg. 2012 Feb; 114(2):410-5.
    View in: PubMed
    Score: 0.409
  9. Xu Z, Dong Y, Wu X, Zhang J, McAuliffe S, Pan C, Zhang Y, Ichinose F, Yue Y, Xie Z. The potential dual effects of anesthetic isoflurane on Aß-induced apoptosis. Curr Alzheimer Res. 2011 Nov; 8(7):741-52.
    View in: PubMed
    Score: 0.409
  10. Zhang Y, Zhen Y, Dong Y, Xu Z, Yue Y, Golde TE, Tanzi RE, Moir RD, Xie Z. Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aß oligomerization. PLoS One. 2011; 6(11):e27019.
    View in: PubMed
    Score: 0.409
  11. Zhang J, Dong Y, Xu Z, Zhang Y, Pan C, McAuliffe S, Ichinose F, Yue Y, Liang W, Xie Z. 2-Deoxy-D-glucose attenuates isoflurane-induced cytotoxicity in an in vitro cell culture model of H4 human neuroglioma cells. Anesth Analg. 2011 Dec; 113(6):1468-75.
    View in: PubMed
    Score: 0.406
  12. Pan C, Xu Z, Dong Y, Zhang Y, Zhang J, McAuliffe S, Yue Y, Li T, Xie Z. The potential dual effects of anesthetic isoflurane on hypoxia-induced caspase-3 activation and increases in ß-site amyloid precursor protein-cleaving enzyme levels. Anesth Analg. 2011 Jul; 113(1):145-52.
    View in: PubMed
    Score: 0.394
  13. Wu X, Lu Y, Dong Y, Zhang G, Zhang Y, Xu Z, Culley DJ, Crosby G, Marcantonio ER, Tanzi RE, Xie Z. The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-a, IL-6, and IL-1ß. Neurobiol Aging. 2012 Jul; 33(7):1364-78.
    View in: PubMed
    Score: 0.385
  14. Zhang Y, Dong Y, Wu X, Lu Y, Xu Z, Knapp A, Yue Y, Xu T, Xie Z. The mitochondrial pathway of anesthetic isoflurane-induced apoptosis. J Biol Chem. 2010 Feb 05; 285(6):4025-37.
    View in: PubMed
    Score: 0.358
  15. Zhen Y, Dong Y, Wu X, Xu Z, Lu Y, Zhang Y, Norton D, Tian M, Li S, Xie Z. Nitrous oxide plus isoflurane induces apoptosis and increases beta-amyloid protein levels. Anesthesiology. 2009 Oct; 111(4):741-52.
    View in: PubMed
    Score: 0.354
  16. Xie Z, Culley DJ, Dong Y, Zhang G, Zhang B, Moir RD, Frosch MP, Crosby G, Tanzi RE. The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo. Ann Neurol. 2008 Dec; 64(6):618-27.
    View in: PubMed
    Score: 0.334
  17. Zhang G, Dong Y, Zhang B, Ichinose F, Wu X, Culley DJ, Crosby G, Tanzi RE, Xie Z. Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci. 2008 Apr 23; 28(17):4551-60.
    View in: PubMed
    Score: 0.320
  18. Zhang B, Dong Y, Zhang G, Moir RD, Xia W, Yue Y, Tian M, Culley DJ, Crosby G, Tanzi RE, Xie Z. The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions. J Biol Chem. 2008 May 02; 283(18):11866-75.
    View in: PubMed
    Score: 0.317
  19. Xie Z, Dong Y, Maeda U, Moir R, Inouye SK, Culley DJ, Crosby G, Tanzi RE. Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. J Gerontol A Biol Sci Med Sci. 2006 Dec; 61(12):1300-6.
    View in: PubMed
    Score: 0.291
  20. Xie Z, Dong Y, Maeda U, Alfille P, Culley DJ, Crosby G, Tanzi RE. The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels. Anesthesiology. 2006 May; 104(5):988-94.
    View in: PubMed
    Score: 0.279
  21. Wang H, Xu Z, Wu A, Dong Y, Zhang Y, Yue Y, Xie Z. 2-deoxy-D-glucose enhances anesthetic effects in mice. Anesth Analg. 2015 Feb; 120(2):312-9.
    View in: PubMed
    Score: 0.128
  22. Li XM, Su F, Ji MH, Zhang GF, Qiu LL, Jia M, Gao J, Xie Z, Yang JJ. Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice. Anesthesiology. 2014 Jul; 121(1):79-88.
    View in: PubMed
    Score: 0.123
  23. Shen X, Dong Y, Xu Z, Wang H, Miao C, Soriano SG, Sun D, Baxter MG, Zhang Y, Xie Z. Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. Anesthesiology. 2013 Mar; 118(3):502-15.
    View in: PubMed
    Score: 0.112
  24. Culley DJ, Boyd JD, Palanisamy A, Xie Z, Kojima K, Vacanti CA, Tanzi RE, Crosby G. Isoflurane decreases self-renewal capacity of rat cultured neural stem cells. Anesthesiology. 2011 Oct; 115(4):754-63.
    View in: PubMed
    Score: 0.102
  25. Palanisamy A, Baxter MG, Keel PK, Xie Z, Crosby G, Culley DJ. Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. Anesthesiology. 2011 Mar; 114(3):521-8.
    View in: PubMed
    Score: 0.097
  26. Culley DJ, Yukhananov RY, Xie Z, Gali RR, Tanzi RE, Crosby G. Altered hippocampal gene expression 2 days after general anesthesia in rats. Eur J Pharmacol. 2006 Nov 07; 549(1-3):71-8.
    View in: PubMed
    Score: 0.071
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.