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Philip Reed Larsen, M.D.

Concepts

This page shows the publications Philip Larsen has written about RNA, Messenger.
Connection Strength

0.642
  1. The mRNA structure has potent regulatory effects on type 2 iodothyronine deiodinase expression. Mol Endocrinol. 2002 Jul; 16(7):1667-79.
    View in: PubMed
    Score: 0.078
  2. Thyroid hormone regulates hyperpolarization-activated cyclic nucleotide-gated channel (HCN2) mRNA in the rat heart. Circ Res. 1999 Sep 17; 85(6):498-503.
    View in: PubMed
    Score: 0.065
  3. Regional expression of the type 3 iodothyronine deiodinase messenger ribonucleic acid in the rat central nervous system and its regulation by thyroid hormone. Endocrinology. 1999 Feb; 140(2):784-90.
    View in: PubMed
    Score: 0.062
  4. The 3'-untranslated region of human type 2 iodothyronine deiodinase mRNA contains a functional selenocysteine insertion sequence element. J Biol Chem. 1998 Dec 11; 273(50):33374-8.
    View in: PubMed
    Score: 0.061
  5. Studies of the hormonal regulation of type 2 5'-iodothyronine deiodinase messenger ribonucleic acid in pituitary tumor cells using semiquantitative reverse transcription-polymerase chain reaction. Endocrinology. 1998 Dec; 139(12):4895-905.
    View in: PubMed
    Score: 0.061
  6. The type I iodothyronine 5'-deiodinase messenger ribonucleic acid is localized to the S3 segment of the rat kidney proximal tubule. Endocrinology. 1993 May; 132(5):2136-40.
    View in: PubMed
    Score: 0.041
  7. Thyroid hormone regulates type I deiodinase messenger RNA in rat liver. Mol Endocrinol. 1990 May; 4(5):743-8.
    View in: PubMed
    Score: 0.034
  8. The imprinted gene neuronatin is regulated by metabolic status and associated with obesity. Obesity (Silver Spring). 2010 Jul; 18(7):1289-96.
    View in: PubMed
    Score: 0.032
  9. Regional physiological adaptation of the central nervous system deiodinases to iodine deficiency. Am J Physiol Endocrinol Metab. 2001 Jul; 281(1):E54-61.
    View in: PubMed
    Score: 0.018
  10. Type 2 iodothyronin deiodinase transgene expression in the mouse heart causes cardiac-specific thyrotoxicosis. Endocrinology. 2001 Jan; 142(1):13-20.
    View in: PubMed
    Score: 0.018
  11. The human, but not rat, dio2 gene is stimulated by thyroid transcription factor-1 (TTF-1). Mol Endocrinol. 2001 Jan; 15(1):112-24.
    View in: PubMed
    Score: 0.018
  12. Characterization of the 5'-flanking and 5'-untranslated regions of the cyclic adenosine 3',5'-monophosphate-responsive human type 2 iodothyronine deiodinase gene. Endocrinology. 2000 Jan; 141(1):229-37.
    View in: PubMed
    Score: 0.016
  13. Type 2 iodothyronine deiodinase is highly expressed in human thyroid. J Clin Invest. 1996 Aug 15; 98(4):962-8.
    View in: PubMed
    Score: 0.013
  14. In vivo genomic footprinting of thyroid hormone-responsive genes in pituitary tumor cell lines. Mol Cell Biol. 1996 Aug; 16(8):4465-77.
    View in: PubMed
    Score: 0.013
  15. Effect of 3,5,3'-Triiodothyronine (T3) administration on dio1 gene expression and T3 metabolism in normal and type 1 deiodinase-deficient mice. Endocrinology. 1995 Nov; 136(11):4842-9.
    View in: PubMed
    Score: 0.012
  16. Type 3 lodothyronine deiodinase: cloning, in vitro expression, and functional analysis of the placental selenoenzyme. J Clin Invest. 1995 Nov; 96(5):2421-30.
    View in: PubMed
    Score: 0.012
  17. Pituitary cells respond to thyroid hormone by discrete, gene-specific pathways. Endocrinology. 1995 Apr; 136(4):1488-94.
    View in: PubMed
    Score: 0.012
  18. Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency. J Clin Invest. 1993 Sep; 92(3):1517-28.
    View in: PubMed
    Score: 0.011
  19. Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3' untranslated region. Nature. 1991 Sep 19; 353(6341):273-6.
    View in: PubMed
    Score: 0.009
  20. Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase. J Biol Chem. 1991 Aug 05; 266(22):14155-8.
    View in: PubMed
    Score: 0.009
  21. Mutations of the rat growth hormone promoter which increase and decrease response to thyroid hormone define a consensus thyroid hormone response element. Mol Endocrinol. 1989 Dec; 3(12):1996-2004.
    View in: PubMed
    Score: 0.008
  22. Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing. Nature. 1989 Feb 16; 337(6208):659-61.
    View in: PubMed
    Score: 0.008
  23. Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse. Endocrinology. 2005 Mar; 146(3):1568-75.
    View in: PubMed
    Score: 0.006
  24. Lipopolysaccharide induces type 2 iodothyronine deiodinase in the mediobasal hypothalamus: implications for the nonthyroidal illness syndrome. Endocrinology. 2004 Apr; 145(4):1649-55.
    View in: PubMed
    Score: 0.005
  25. The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J Clin Invest. 2001 Nov; 108(9):1379-85.
    View in: PubMed
    Score: 0.005
  26. The human type 2 iodothyronine deiodinase is a selenoprotein highly expressed in a mesothelioma cell line. J Biol Chem. 2001 Aug 10; 276(32):30183-7.
    View in: PubMed
    Score: 0.005
  27. DARPP-32 and CREB are present in type 2 iodothyronine deiodinase-producing tanycytes: implications for the regulation of type 2 deiodinase activity. Brain Res. 2000 Apr 17; 862(1-2):154-61.
    View in: PubMed
    Score: 0.004
  28. Characterization of the promoter of the rat sarcoplasmic endoplasmic reticulum Ca2+-ATPase 1 gene and analysis of thyroid hormone responsiveness. J Biol Chem. 1996 Dec 13; 271(50):32048-56.
    View in: PubMed
    Score: 0.003
  29. Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5031-5.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.