Harvard Catalyst Profiles

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Philip Reed Larsen, M.D.

Concepts

This page shows the publications Philip Larsen has written about Cysteine.
Connection Strength

0.567
  1. The role of the active site cysteine in catalysis by type 1 iodothyronine deiodinase. Endocrinology. 1997 Dec; 138(12):5452-8.
    View in: PubMed
    Score: 0.124
  2. Substitution of cysteine for selenocysteine in type I iodothyronine deiodinase reduces the catalytic efficiency of the protein but enhances its translation. Endocrinology. 1992 Oct; 131(4):1848-52.
    View in: PubMed
    Score: 0.087
  3. Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3' untranslated region. Nature. 1991 Sep 19; 353(6341):273-6.
    View in: PubMed
    Score: 0.081
  4. Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase. J Biol Chem. 1991 Aug 05; 266(22):14155-8.
    View in: PubMed
    Score: 0.080
  5. Evidence that cysteine, not selenocysteine, is in the catalytic site of type II iodothyronine deiodinase. Endocrinology. 1991 Jul; 129(1):550-2.
    View in: PubMed
    Score: 0.080
  6. The role of selenocysteine 133 in catalysis by the human type 2 iodothyronine deiodinase. Endocrinology. 2000 Dec; 141(12):4606-12.
    View in: PubMed
    Score: 0.038
  7. Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center. Endocrinology. 2000 Mar; 141(3):1127-35.
    View in: PubMed
    Score: 0.036
  8. The role of selenium in thyroid hormone action. Endocr Rev. 1992 May; 13(2):207-19.
    View in: PubMed
    Score: 0.021
  9. Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature. 1991 Jan 31; 349(6308):438-40.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.