Concepts
This page shows the publications Philip Larsen has written about Amino Acid Sequence.
Connection Strength
0.319
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The mRNA structure has potent regulatory effects on type 2 iodothyronine deiodinase expression. Mol Endocrinol. 2002 Jul; 16(7):1667-79.
Score: 0.024
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Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev. 2002 Feb; 23(1):38-89.
Score: 0.023
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Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center. Endocrinology. 2000 Mar; 141(3):1127-35.
Score: 0.020
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Cloning and expression of the chicken type 2 iodothyronine 5'-deiodinase. J Biol Chem. 1999 May 14; 274(20):13768-76.
Score: 0.019
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The guanosine monophosphate reductase gene is conserved in rats and its expression increases rapidly in brown adipose tissue during cold exposure. J Biol Chem. 1998 Nov 20; 273(47):31092-6.
Score: 0.019
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The role of the active site cysteine in catalysis by type 1 iodothyronine deiodinase. Endocrinology. 1997 Dec; 138(12):5452-8.
Score: 0.017
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Update on the human iodothyronine selenodeiodinases, the enzymes regulating the activation and inactivation of thyroid hormone. Biochem Soc Trans. 1997 May; 25(2):588-92.
Score: 0.017
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Molecular biological and biochemical characterization of the human type 2 selenodeiodinase. Endocrinology. 1996 Aug; 137(8):3308-15.
Score: 0.016
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Structural features of thyroid hormone response elements that increase susceptibility to inhibition by an RTH mutant thyroid hormone receptor. Endocrinology. 1996 Jul; 137(7):2833-41.
Score: 0.016
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The structure of the coding and 5'-flanking region of the type 1 iodothyronine deiodinase (dio1) gene is normal in a patient with suspected congenital dio1 deficiency. J Clin Endocrinol Metab. 1996 Jun; 81(6):2121-4.
Score: 0.016
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Type 3 lodothyronine deiodinase: cloning, in vitro expression, and functional analysis of the placental selenoenzyme. J Clin Invest. 1995 Nov; 96(5):2421-30.
Score: 0.015
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Structural and functional differences in the dio1 gene in mice with inherited type 1 deiodinase deficiency. Mol Endocrinol. 1995 Aug; 9(8):969-80.
Score: 0.015
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Topological analysis of the integral membrane protein, type 1 iodothyronine deiodinase (D1). J Biol Chem. 1995 May 19; 270(20):12310-8.
Score: 0.015
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Nutritional and hormonal regulation of thyroid hormone deiodinases. Annu Rev Nutr. 1995; 15:323-52.
Score: 0.014
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Identification of critical amino acids for 3,5,3'-triiodothyronine deiodination by human type 1 deiodinase based on comparative functional-structural analyses of the human, dog, and rat enzymes. J Biol Chem. 1994 Aug 12; 269(32):20329-34.
Score: 0.014
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Type I iodothyronine deiodinase: unexpected complexities in a simple deiodination reaction. Thyroid. 1994; 4(3):357-62.
Score: 0.013
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Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase. J Clin Endocrinol Metab. 1992 Oct; 75(4):1133-9.
Score: 0.012
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Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature. 1991 Jan 31; 349(6308):438-40.
Score: 0.011
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The thyroid hormone-inactivating deiodinase functions as a homodimer. Mol Endocrinol. 2008 Jun; 22(6):1382-93.
Score: 0.009
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The iodothyronine selenodeiodinases are thioredoxin-fold family proteins containing a glycoside hydrolase clan GH-A-like structure. J Biol Chem. 2003 Sep 19; 278(38):36887-96.
Score: 0.006
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Structure-activity relationships for thyroid hormone deiodination by mammalian type I iodothyronine deiodinases. Endocrinology. 1997 Jan; 138(1):213-9.
Score: 0.004
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Identification of a thyroid hormone receptor that is pituitary-specific. Science. 1989 Apr 07; 244(4900):76-9.
Score: 0.002
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Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5031-5.
Score: 0.002
Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.