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profileThomas T. Simopoulos, M.D.

TitleAssistant Professor of Anaesthesia
InstitutionBeth Israel Deaconess Medical Center
DepartmentAnaesthesia
AddressBeth Israel Deaconess Med Ctr
Anesthesia & Critical Care Stoneman 308
330 Brookline Ave
Boston MA 02215
Phone617/667-3112
Fax617/667-7849
vCardDownload vCard (login for email)

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Simopoulos T, Sharma S, Aner M, Gill JS. A Temporary vs. Permanent Anchored Percutaneous Lead Trial of Spinal Cord Stimulation: A Comparison of Patient Outcomes and Adverse Events. Neuromodulation. 2017 Sep 13. PMID: 28901641.
    View in: PubMed
  2. Helm Ii S, Simopoulos TT, Stojanovic M, Abdi S, El Terany MA. Effectiveness of Thermal Annular Procedures in Treating Discogenic Low Back Pain. Pain Physician. 2017 Sep; 20(6):447-470. PMID: 28934777.
    View in: PubMed
  3. Bendel MA, O'Brien T, Hoelzer BC, Deer TR, Pittelkow TP, Costandi S, Walega DR, Azer G, Hayek SM, Wang Z, Eldrige JS, Qu W, Rosenow JM, Falowski SM, Neuman SA, Moeschler SM, Wassef C, Kim C, Niazi T, Saifullah T, Yee B, Kim C, Oryhan CL, Warren DT, Lerman I, Mora R, Hanes M, Simopoulos T, Sharma S, Gilligan C, Grace W, Ade T, Mekhail NA, Hunter JP, Choi D, Choi DY. Spinal Cord Stimulator Related Infections: Findings From a Multicenter Retrospective Analysis of 2737 Implants. Neuromodulation. 2017 Aug; 20(6):553-557. PMID: 28726312.
    View in: PubMed
  4. Gill J, Simopoulos T. Reliability and Accuracy of MRI Laminar Angle Measurements to Determine Intraprocedural Contralateral Oblique View Angle for Cervical or Thoracic Interlaminar Epidural Steroid Injections-Safety Before Accuracy. Pain Med. 2017 Jun 07. PMID: 28591865.
    View in: PubMed
  5. Gill J, Nagda J, Aner M, Simopoulos T. Cervical Epidural Contrast Spread Patterns in Fluoroscopic Antero-Posterior, Lateral, and Contralateral Oblique View: A Three-Dimensional Analysis. Pain Med. 2017 Jun 01; 18(6):1027-1039. PMID: 28339542.
    View in: PubMed
  6. Hoelzer BC, Bendel MA, Deer TR, Eldrige JS, Walega DR, Wang Z, Costandi S, Azer G, Qu W, Falowski SM, Neuman SA, Moeschler SM, Wassef C, Kim C, Niazi T, Saifullah T, Yee B, Kim C, Oryhan CL, Rosenow JM, Warren DT, Lerman I, Mora R, Hayek SM, Hanes M, Simopoulos T, Sharma S, Gilligan C, Grace W, Ade T, Mekhail NA, Hunter JP, Choi D, Choi DY. Spinal Cord Stimulator Implant Infection Rates and Risk Factors: A Multicenter Retrospective Study. Neuromodulation. 2017 Aug; 20(6):558-562. PMID: 28493599.
    View in: PubMed
  7. Simopoulos T, Leffler D, Barnett S, Campbell D, Lian SJ, Gill JS. Prospective Assessment of Pain and Comfort in Chronic Pain Patients Undergoing Interventional Pain Management Procedures. Pain Med. 2017 Apr 18. PMID: 28431040.
    View in: PubMed
  8. Gill JS, Simopoulos TT. Reliability and Safety of Contra-Lateral Oblique View for Interlaminar Epidural Needle Placement: Standardization of the Appropriate Angle. Pain Physician. 2017 Mar; 20(3):E469. PMID: 28339450.
    View in: PubMed
  9. Gill JS, Simopoulos TT. Optimal Angle of Contralateral Oblique View in Cervical Interlaminar Epidural Injections: Safety or Precision? Pain Physician. 2017 Mar; 20(3):E478-E479. PMID: 28339454.
    View in: PubMed
  10. Spinner D, Aner M, Paul G, Simopoulos T, Gill J. Percutaneous Translaminar Facet Cyst Rupture and Epidural Access-Description of a Novel Technique. Pain Med. 2017 03 01; 18(3):410-413. PMID: 28395102.
    View in: PubMed
  11. Manchikanti L, Kaye AM, Knezevic NN, McAnally H, Slavin K, Trescot AM, Blank S, Pampati V, Abdi S, Grider JS, Kaye AD, Manchikanti KN, Cordner H, Gharibo CG, Harned ME, Albers SL, Atluri S, Aydin SM, Bakshi S, Barkin RL, Benyamin RM, Boswell MV, Buenaventura RM, Calodney AK, Cedeno DL, Datta S, Deer TR, Fellows B, Galan V, Grami V, Hansen H, Helm Ii S, Justiz R, Koyyalagunta D, Malla Y, Navani A, Nouri KH, Pasupuleti R, Sehgal N, Silverman SM, Simopoulos TT, Singh V, Solanki DR, Staats PS, Vallejo R, Wargo BW, Watanabe A, Hirsch JA. Responsible, Safe, and Effective Prescription of Opioids for Chronic Non-Cancer Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines. Pain Physician. 2017 Feb; 20(2S):S3-S92. PMID: 28226332.
    View in: PubMed
  12. Simopoulos TT, Sharma S, Aner M, Gill JS. The Incidence and Management of Postdural Puncture Headache in Patients Undergoing Percutaneous Lead Placement for Spinal Cord Stimulation. Neuromodulation. 2016 Oct; 19(7):738-743. PMID: 27172329.
    View in: PubMed
  13. Gill JS, Stojanovic M, Simopoulos TT. In Defense of the Meticulous: A Case Against Ambiguity, and a Time to Standardize. Pain Physician. 2016 05; 19(4):E657-8. PMID: 27228534.
    View in: PubMed
  14. Gill JS, Simopoulos T. The Devil Is in the Details. Anesthesiology. 2016 Jan; 124(1):241. PMID: 26669991.
    View in: PubMed
  15. Gill JS, Nagda JV, Aner MM, Keel JC, Simopoulos TT. Contralateral Oblique View Is Superior to the Lateral View for Lumbar Epidural Access. Pain Med. 2016 05; 17(5):839-50. PMID: 26814266.
    View in: PubMed
  16. Simopoulos TT, Rosa H, Wootton J, Eichman DS, Gill JS. A Survey of Spinal Cord Stimulator Use by Chronic Pain Patients While Driving. Neuromodulation. 2016 Jul; 19(5):487-91. PMID: 26559374.
    View in: PubMed
  17. Simopoulos TT, Manchikanti L, Gupta S, Aydin SM, Kim CH, Solanki D, Nampiaparampil DE, Singh V, Staats PS, Hirsch JA. Systematic Review of the Diagnostic Accuracy and Therapeutic Effectiveness of Sacroiliac Joint Interventions. Pain Physician. 2015 Sep-Oct; 18(5):E713-56. PMID: 26431129.
    View in: PubMed
  18. Boswell MV, Manchikanti L, Kaye AD, Bakshi S, Gharibo CG, Gupta S, Jha SS, Nampiaparampil DE, Simopoulos TT, Hirsch JA. A Best-Evidence Systematic Appraisal of the Diagnostic Accuracy and Utility of Facet (Zygapophysial) Joint Injections in Chronic Spinal Pain. Pain Physician. 2015 Jul-Aug; 18(4):E497-533. PMID: 26218947.
    View in: PubMed
  19. Manchikanti L, Nampiaparampil DE, Manchikanti KN, Falco FJ, Singh V, Benyamin RM, Kaye AD, Sehgal N, Soin A, Simopoulos TT, Bakshi S, Gharibo CG, Gilligan CJ, Hirsch JA. Comparison of the efficacy of saline, local anesthetics, and steroids in epidural and facet joint injections for the management of spinal pain: A systematic review of randomized controlled trials. Surg Neurol Int. 2015; 6(Suppl 4):S194-235. PMID: 26005584; PMCID: PMC4431057.
  20. Gill JS, Aner M, Nagda JV, Jyotsna N, Keel JC, Simopoulos TT. Contralateral oblique view is superior to lateral view for interlaminar cervical and cervicothoracic epidural access. Pain Med. 2015 Jan; 16(1):68-80. PMID: 25220833.
    View in: PubMed
  21. Manchikanti L, Atluri S, Candido KD, Boswell MV, Simopoulos TT, Grider JS, Falco FJ, Hirsch JA. Zohydro approval by food and drug administration: controversial or frightening? Pain Physician. 2014 Jul-Aug; 17(4):E437-50. PMID: 25054396.
    View in: PubMed
  22. Manchikanti L, Hirsch JA, Heavner JE, Cohen SP, Benyamin RM, Sehgal N, Falco FJ, Vallejo R, Onyewu O, Zhu J, Kaye AD, Boswell MV, Helm S, Candido KD, Diwan S, Simopoulos TT, Singh V, Pampati V, Racz GB, Raj PP. Development of an interventional pain management specific instrument for methodologic quality assessment of nonrandomized studies of interventional techniques. Pain Physician. 2014 May-Jun; 17(3):E291-317. PMID: 24850112.
    View in: PubMed
  23. Jang SS, Arle JE, Gill JS, Simopoulos TT. Case series on variable presentation of ligamentum flavum stimulation following percutaneous cylindrical spinal cord stimulator lead implants. Pain Physician. 2014 May-Jun; 17(3):E397-403. PMID: 24850121.
    View in: PubMed
  24. Chaudhry ZA, Najib U, Bajwa ZH, Jacobs WC, Sheikh J, Simopoulos TT. Detailed analysis of allergic cutaneous reactions to spinal cord stimulator devices. J Pain Res. 2013; 6:617-23. PMID: 23946668; PMCID: PMC3738259.
  25. Gill J, Aner M, Simopoulos T. Intricacies of the contralateral oblique view for interlaminar epidural access. Pain Med. 2013 Aug; 14(8):1265-6. PMID: 23659540.
    View in: PubMed
  26. Simopoulos TT, Gill JS. Magnetic resonance imaging of the lumbar spine in a patient with a spinal cord stimulator. Pain Physician. 2013 May-Jun; 16(3):E295-300. PMID: 23703428.
    View in: PubMed
  27. Manchikanti L, Abdi S, Atluri S, Benyamin RM, Boswell MV, Buenaventura RM, Bryce DA, Burks PA, Caraway DL, Calodney AK, Cash KA, Christo PJ, Cohen SP, Colson J, Conn A, Cordner H, Coubarous S, Datta S, Deer TR, Diwan S, Falco FJ, Fellows B, Geffert S, Grider JS, Gupta S, Hameed H, Hameed M, Hansen H, Helm S, Janata JW, Justiz R, Kaye AD, Lee M, Manchikanti KN, McManus CD, Onyewu O, Parr AT, Patel VB, Racz GB, Sehgal N, Sharma ML, Simopoulos TT, Singh V, Smith HS, Snook LT, Swicegood JR, Vallejo R, Ward SP, Wargo BW, Zhu J, Hirsch JA. An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations. Pain Physician. 2013 Apr; 16(2 Suppl):S49-283. PMID: 23615883.
    View in: PubMed
  28. Slavin KV, Vaisman J, Pollack KL, Simopoulos TT, Kowlowitz E, Weinand ME, Norregaard TV. Treatment of chronic, intractable pain with a conventional implantable pulse generator: a meta-analysis of 4 clinical studies. Clin J Pain. 2013 Jan; 29(1):78-85. PMID: 22751030.
    View in: PubMed
  29. Falco FJ, Manchikanti L, Datta S, Sehgal N, Geffert S, Onyewu O, Singh V, Bryce DA, Benyamin RM, Simopoulos TT, Vallejo R, Gupta S, Ward SP, Hirsch JA. An update of the systematic assessment of the diagnostic accuracy of lumbar facet joint nerve blocks. Pain Physician. 2012 Nov-Dec; 15(6):E869-907. PMID: 23159979.
    View in: PubMed
  30. Hansen H, Manchikanti L, Simopoulos TT, Christo PJ, Gupta S, Smith HS, Hameed H, Cohen SP. A systematic evaluation of the therapeutic effectiveness of sacroiliac joint interventions. Pain Physician. 2012 May-Jun; 15(3):E247-78. PMID: 22622913.
    View in: PubMed
  31. Simopoulos TT, Manchikanti L, Singh V, Gupta S, Hameed H, Diwan S, Cohen SP. A systematic evaluation of prevalence and diagnostic accuracy of sacroiliac joint interventions. Pain Physician. 2012 May-Jun; 15(3):E305-44. PMID: 22622915.
    View in: PubMed
  32. Simopoulos TT, Nagda J, Aner MM. Percutaneous radiofrequency lesioning of the suprascapular nerve for the management of chronic shoulder pain: a case series. J Pain Res. 2012; 5:91-7. PMID: 22570561; PMCID: PMC3346065.
  33. Rhame EE, Debonet AF, Simopoulos TT. Ultrasonographic guidance and characterization of cryoanalgesic lesions in treating a case of refractory sural neuroma. Case Rep Anesthesiol. 2011; 2011:691478. PMID: 22606391; PMCID: PMC3350006.
  34. Nagda JV, Davis CW, Bajwa ZH, Simopoulos TT. Retrospective review of the efficacy and safety of repeated pulsed and continuous radiofrequency lesioning of the dorsal root ganglion/segmental nerve for lumbar radicular pain. Pain Physician. 2011 Jul-Aug; 14(4):371-6. PMID: 21785480.
    View in: PubMed
  35. Bernardini DJ, Pratt SD, Takoudes TC, Simopoulos TT. Spinal cord stimulation and the pregnant patient-specific considerations for management: A case series and review of the literature. Neuromodulation. 2010 Oct; 13(4):270-4. PMID: 21992881.
    View in: PubMed
  36. Simopoulos T, Bajwa Z, Lantz G, Lee S, Burstein R. Implanted auriculotemporal nerve stimulator for the treatment of refractory chronic migraine. Headache. 2010 Jun; 50(6):1064-9. PMID: 20618819.
    View in: PubMed
  37. Lowry AM, Simopoulos TT. Spinal cord stimulation for the treatment of chronic knee pain following total knee replacement. Pain Physician. 2010 May-Jun; 13(3):251-6. PMID: 20495589.
    View in: PubMed
  38. Gerszten PC, Smuck M, Rathmell JP, Simopoulos TT, Bhagia SM, Mocek CK, Crabtree T, Bloch DA. Plasma disc decompression compared with fluoroscopy-guided transforaminal epidural steroid injections for symptomatic contained lumbar disc herniation: a prospective, randomized, controlled trial. J Neurosurg Spine. 2010 Apr; 12(4):357-71. PMID: 20201654.
    View in: PubMed
  39. Bajwa ZH, Simopoulos TT, Pal J, Kraemer JJ, Chopra P, Nagda JV, Najib U, Celestin J, Sial K, Ahmad B, Warfield C, Steinman TI, Wootton J. Low and therapeutic doses of antidepressants are associated with similar response in the context of multimodal treatment of pain. Pain Physician. 2009 Sep-Oct; 12(5):893-900. PMID: 19787016.
    View in: PubMed
  40. Simopoulos TT, Kraemer JJ, Glazer P, Bajwa ZH. Vertebral osteomyelitis: a potentially catastrophic outcome after lumbar epidural steroid injection. Pain Physician. 2008 Sep-Oct; 11(5):693-7. PMID: 18850035.
    View in: PubMed
  41. Ramanavarapu V, Simopoulos TT. Pulsed radiofrequency of lumbar dorsal root ganglia for chronic post-amputation stump pain. Pain Physician. 2008 Jul-Aug; 11(4):561-6. PMID: 18690285.
    View in: PubMed
  42. Simopoulos TT, Kraemer J, Nagda JV, Aner M, Bajwa ZH. Response to pulsed and continuous radiofrequency lesioning of the dorsal root ganglion and segmental nerves in patients with chronic lumbar radicular pain. Pain Physician. 2008 Mar-Apr; 11(2):137-44. PMID: 18354708.
    View in: PubMed
  43. Elkersh MA, Simopoulos TT, Bajwa ZH. Fundamentals of interventional pain medicine. Neurologist. 2005 Sep; 11(5):285-93. PMID: 16148735.
    View in: PubMed
  44. Simopoulos TT, Malik AB, Sial KA, Elkersh M, Bajwa ZH. Radiofrequency lesioning of the L2 ramus communicans in managing discogenic low back pain. Pain Physician. 2005 Jan; 8(1):61-5. PMID: 16850044.
    View in: PubMed
  45. Hosny A, Simopoulos T, Collins B. Response of intractable post herpetic neuralgia to intrathecal baclofen. Pain Physician. 2004 Jul; 7(3):345-7. PMID: 16858473.
    View in: PubMed
  46. Elkersh MA, Simopoulos TT, Malik AB, Cho EH, Bajwa ZH. Epidural clonidine relieves intractable neuropathic itch associated with herpes zoster-related pain. Reg Anesth Pain Med. 2003 Jul-Aug; 28(4):344-6. PMID: 12945030.
    View in: PubMed
  47. Simopoulos TT, Smith HS, Peeters-Asdourian C, Stevens DS. Use of meperidine in patient-controlled analgesia and the development of a normeperidine toxic reaction. Arch Surg. 2002 Jan; 137(1):84-8. PMID: 11772223.
    View in: PubMed
  48. Simopoulos T, Peeters-Asdourian C. Pneumocephalus after cervical epidural steroid injection. Anesth Analg. 2001 Jun; 92(6):1576-7. PMID: 11375849.
    View in: PubMed
  49. Simopoulos TT, Jencks WP. Alkaline phosphatase is an almost perfect enzyme. Biochemistry. 1994 Aug 30; 33(34):10375-80. PMID: 8068674.
    View in: PubMed
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