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Steven Gary DuBois, M.D.

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Mentoring
current student opportunities
Available: 02/24/25, Expires: 05/05/25

Phase 1 trials are the usual starting place for development of novel therapies. Drug development in pediatric oncology poses particular challenges given patient age and rarity of these diseases. Prior work from our group has shown a significant delay from time from start of first-in-human clinical trials of oncology drugs to initiation of first-in-child clinical trials. Once a drug enters the pediatric oncology clinic through early phase trials, the disposition of that drug is not clear, including key metrics such as probability of regulatory approval and probability of subsequent clinical trials. We are seeking a student interested in evaluating drug development databases to catalogue these outcomes, including potential predictors of higher probability of successful drug development. This project can be completed remotely and does not require IRB approval, so is ready to begin at any time.


Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01CA214912 (DUBOIS, STEVEN) Apr 15, 2018 - Mar 31, 2025
    NIH
    Tumor and host markers of clinical outcomes after MIBG therapy in neuroblastoma
    Role: Principal Investigator
  2. R01FD005740 (DUBOIS, STEVEN) Sep 1, 2017 - Aug 31, 2020
    NIH
    PhI trial of dual PI3K/BRD4 inhibitor SF1126 in neuroblastoma IND124993 (12/2/14)
    Role: Principal Investigator
  3. R01CA172067 (DUBOIS, STEVEN) Apr 4, 2013 - Mar 31, 2020
    NIH
    Optimizing 131I-mIBG Therapy for Children with Advanced Neuroblastoma
    Role: Principal Investigator
  4. K23CA154530 (DUBOIS, STEVEN) Sep 16, 2011 - Aug 31, 2014
    NIH
    Bone Marrow Micrometastatic Disease in Ewing Sarcoma
    Role: Principal Investigator

Bibliographic
selected publications
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© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.