Harvard Catalyst Profiles

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Irun Bhan, M.D.

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selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Taylor MS, Connie W, Fridy PC, Zhang SJ, Senussi Y, Wolters JC, Cheng WC, Heaps J, Miller BD, Mori K, Cohen L, Jiang H, Molloy KR, Norden BL, Chait BT, Goggins M, Bhan I, Franses JW, Yang X, Taplin ME, Wang X, Christiani DC, Johnson BE, Meyerson M, Uppaluri R, Egloff AM, Denault EN, Spring LM, Wang TL, Shih IM, Jung E, Arora KS, Zukerberg LR, Yilmaz OH, Chi G, Matulonis UA, Song Y, Nieman L, Parikh AR, Strickland M, Corcoran RB, Mustelin T, Eng G, Yilmaz ÃH, Skates SJ, Rueda BR, Drapkin R, Klempner SJ, Deshpande V, Ting DT, Rout MP, LaCava J, Walt DR, Burns KH. Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker. bioRxiv. 2023 Mar 17. PMID: 36747644; PMCID: PMC9900799.
    Citations:    
  2. Pal Chaudhary S, Reyes S, Chase ML, Govindan A, Zhao L, Luther J, Bhan I, Bethea E, Franses JW, Paige Walsh E, Anne Dageford L, Kimura S, Elias N, Yeh H, Markman J, Bozorgzadeh A, Tanabe K, Ferrone C, Zhu AX, Andersson K, Thiim M, Antonio Catalano O, Kambadakone A, Vagefi PA, Qadan M, Pratt D, Hashemi N, Corey KE, Misdraji J, Goyal L, Clark JW. Resection of NAFLD/NASH-related Hepatocellular Carcinoma (HCC): Clinical Features and Outcomes Compared with HCC Due to Other Etiologies. Oncologist. 2023 Feb 10. PMID: 36763374.
    Citations:    Fields:    
  3. Bhan I, Schaefer EA, Bradley WR, Rodriguez-Lopez JM, Crowley JC, Hutchison B. Case 4-2023: A 56-Year-Old Man with Abnormal Results on Liver Testing. N Engl J Med. 2023 Feb 09; 388(6):544-554. PMID: 36780679.
    Citations:    Fields:    Translation:Humans
  4. Boyraz B, Agarwal S, Pratt DS, Simoneau T, Bhan I, Markmann JF, Misdraji J. Hepatic vascular remodelling in a patient with dyskeratosis congenita. Histopathology. 2022 01; 80(2):450-453. PMID: 34327718.
    Citations:    Fields:    Translation:Humans
  5. Franses JW, Bhan I, Zhu AX. PLSec: A novel, liquid biomarker for HCC risk. Med (N Y). 2021 07 09; 2(7):788-790. PMID: 35590215.
    Citations: 1     Translation:Humans
  6. Franses JW, Bhan I, Pankaj A, Ting DT, Deshpande V, Tanabe K. Spontaneous Immune-Mediated Regression of Hepatocellular Carcinoma With High Tumor Mutational Burden. JCO Precis Oncol. 2021; 5. PMID: 34585041; PMCID: PMC8462656.
    Citations: 1     Fields:    Translation:Humans
  7. Liu J, Sun X, Ganguli S, Wehrenberg-Klee EP, Bhan I, Zhao Y, Zhao L, Meng K, Sun R, Yu H, Sun G. Partial splenic embolization is superior to intravenous somatostatin for decreasing portal pressure in cirrhotic patients: a dynamic self-controlled cohort study. Scand J Gastroenterol. 2020 Nov; 55(11):1341-1346. PMID: 33076704.
    Citations: 2     Fields:    Translation:Humans
  8. Bloom PP, Pasricha TS, Andersson KL, Pratt DS, Hashemi N, Bhan I, Viveiros K. Hepatology Consultants Often Disagree on Etiology of Abnormal Liver Biochemistries in COVID-19 but Agree on Management. Dig Dis Sci. 2021 06; 66(6):1852-1854. PMID: 32729013; PMCID: PMC7388107.
    Citations: 1     Fields:    Translation:Humans
  9. Franses JW, Philipp J, Missios P, Bhan I, Liu A, Yashaswini C, Tai E, Zhu H, Ligorio M, Nicholson B, Tassoni EM, Desai N, Kulkarni AS, Szabolcs A, Hong TS, Liss AS, Fernandez-Del Castillo C, Ryan DP, Maheswaran S, Haber DA, Daley GQ, Ting DT. Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target. Nat Commun. 2020 07 03; 11(1):3303. PMID: 32620742; PMCID: PMC7335061.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  10. Bhan I, Ting DT. Somatic Mutations in Liver Disease: Adaptation Without Carcinogenesis? Hepatology. 2020 06; 71(6):2162-2163. PMID: 32034958.
    Citations:    Fields:    Translation:Humans
  11. Bethea E, Arvind A, Gustafson J, Andersson K, Pratt D, Bhan I, Thiim M, Corey K, Bloom P, Markmann J, Yeh H, Elias N, Kimura S, Dageforde LA, Cuenca A, Kawai T, Safa K, Williams W, Gilligan H, Sise M, Fishman J, Kotton C, Kim A, Rogers CC, Shao S, Cote M, Irwin L, Myoung P, Chung RT. Immediate administration of antiviral therapy after transplantation of hepatitis C-infected livers into uninfected recipients: Implications for therapeutic planning. Am J Transplant. 2020 06; 20(6):1619-1628. PMID: 31887236; PMCID: PMC8005111.
    Citations: 9     Fields:    Translation:HumansCells
  12. Bethea ED, Gaj K, Gustafson JL, Axtell A, Lebeis T, Schoenike M, Turvey K, Coglianese E, Thomas S, Newton-Cheh C, Ibrahim N, Carlson W, Ho JE, Shah R, Nayor M, Gift T, Shao S, Dugal A, Markmann J, Elias N, Yeh H, Andersson K, Pratt D, Bhan I, Safa K, Fishman J, Kotton C, Myoung P, Villavicencio MA, D'Alessandro D, Chung RT, Lewis GD. Pre-emptive pangenotypic direct acting antiviral therapy in donor HCV-positive to recipient HCV-negative heart transplantation: an open-label study. Lancet Gastroenterol Hepatol. 2019 10; 4(10):771-780. PMID: 31353243.
    Citations: 17     Fields:    Translation:HumansCellsCTClinical Trials
  13. Ufere NN, Donlan J, Waldman L, Patel A, Dienstag JL, Friedman LS, Corey KE, Hashemi N, Carolan P, Mullen AC, Thiim M, Bhan I, Nipp R, Greer J, Temel J, Chung RT, El-Jawahri A. Physicians' Perspectives on Palliative Care for Patients With End-Stage Liver Disease: A National Survey Study. Liver Transpl. 2019 06; 25(6):859-869. PMID: 30963669; PMCID: PMC6529275.
    Citations: 12     Fields:    Translation:Humans
  14. Bhan I, Aryee M, Ting DT. Reply. Gastroenterology. 2019 05; 156(6):1933-1934. PMID: 30928436.
    Citations:    Fields:    Translation:HumansCells
  15. Ufere NN, Donlan J, Waldman L, Dienstag JL, Friedman LS, Corey KE, Hashemi N, Carolan P, Mullen AC, Thiim M, Bhan I, Nipp R, Greer JA, Temel JS, Chung RT, El-Jawahri A. Barriers to Use of Palliative Care and Advance Care Planning Discussions for Patients With End-Stage Liver Disease. Clin Gastroenterol Hepatol. 2019 11; 17(12):2592-2599. PMID: 30885884; PMCID: PMC6745282.
    Citations: 19     Fields:    Translation:Humans
  16. Bhan I, Mosesso K, Goyal L, Philipp J, Kalinich M, Franses JW, Choz M, Oklu R, Toner M, Maheswaran S, Haber DA, Zhu AX, Chung RT, Aryee M, Ting DT. Detection and Analysis of Circulating Epithelial Cells in Liquid Biopsies From Patients With Liver Disease. Gastroenterology. 2018 12; 155(6):2016-2018.e11. PMID: 30218669; PMCID: PMC6347478.
    Citations: 11     Fields:    Translation:HumansCells
  17. Bhan I, Kedrin D, Richter JM. Acute Lower Gastrointestinal Bleeding. N Engl J Med. 2017 06 08; 376(23):e50. PMID: 28594156.
    Citations:    Fields:    Translation:Humans
  18. Kalinich M, Bhan I, Kwan TT, Miyamoto DT, Javaid S, LiCausi JA, Milner JD, Hong X, Goyal L, Sil S, Choz M, Ho U, Kapur R, Muzikansky A, Zhang H, Weitz DA, Sequist LV, Ryan DP, Chung RT, Zhu AX, Isselbacher KJ, Ting DT, Toner M, Maheswaran S, Haber DA. An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma. Proc Natl Acad Sci U S A. 2017 01 31; 114(5):1123-1128. PMID: 28096363; PMCID: PMC5293050.
    Citations: 76     Fields:    Translation:HumansCells
  19. Batchelor E, Mock CS, Bhan I, Loewer A, Lahav G. Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage. Mol Cell. 2008 May 09; 30(3):277-89. PMID: 18471974; PMCID: PMC2579769.
    Citations: 179     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.