Anna Christina Muriel, M.D.
Associate Professor of Psychiatry
Dana-Farber Cancer Institute
Dana Farber Cancer Institute
Pediatric Psychosocial Oncology
44 Binney St
Boston MA 02115
Available: 01/10/22, Expires: 12/01/22
Acute Lymphoblastic Leukemia (ALL) is the most common childhood cancer and requires two to three years of treatment with corticosteroids every few weeks to achieve very high survival rates. Steroids are an essential component of curative ALL treatment and yet have significant neuropsychiatric side effects that decrease quality of life for children with cancer and their families. Steroids can cause irritability, insomnia, increased appetite, behavior problems, and aggression, which are extremely challenging for children and families. Periodic behavioral issues disrupt children's schooling, family life, and social development. Identifying and measuring these symptoms is a first step in supporting families and alleviating this source of distress. There is no standardized questionnaire to help patients and oncology teams identify and measure these emotional and behavioral symptoms. This study will use focus groups and written input from parents and oncology staff to develop a validated questionnaire of steroid induced mood symptoms. Qualitative focus group data will be analyzed to determine the most common and challenging symptoms observed by parents and staff. These qualitative themes will then be used to create a standardized questionnaire to identify symptoms and measure their intensity. Such a questionnaire would help families and oncology staff better understand these side effects and access appropriate support and interventions to improve quality of life for children and their families during treatment for childhood leukemia. Students would have the opportunity to collaborate with the study team and the Data Survey Core at DFCI in collecting and analyzing qualitative data from focus groups and learn the steps in measure development. They would also have an opportunity to do some clinical shadowing and understand more about the management of the emotional and behavioral side effects of cancer treatment in youth.
Caregiver Medical Traumatic Stress in Newly Diagnosed Pediatric Cancer Patients: Associated Psychosocial Variables and Implications
Summer, 07/01/13 - 08/16/13
The research activities and funding listed below are automatically derived from
NIH ExPORTER and other sources, which might result in incorrect or missing items.
to make corrections and additions.
(MURIEL, ANNA C)
Sep 27, 2006 - Aug 31, 2009
A Study of Distress and Parenting Concerns Among Adults with Cancer
Role: Principal Investigator
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