Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Gordon Harold Williams, M.D.

Co-Author

This page shows the publications co-authored by Gordon Williams and Gail Adler.
Connection Strength

6.497
  1. Aldosterone: villain or protector? Hypertension. 2007 Jul; 50(1):31-2.
    View in: PubMed
    Score: 0.356
  2. Biological sex modifies aldosterone's secretion at a cellular level. J Endocrinol. 2021 11 24; 252(1):1-13.
    View in: PubMed
    Score: 0.243
  3. Genetic Predictors of Salt Sensitivity of Blood Pressure: The Additive Impact of 2 Hits in the Same Biological Pathway. Hypertension. 2021 12; 78(6):1809-1817.
    View in: PubMed
    Score: 0.242
  4. The Role of Thyroid in Renovascular Function: Independent Association of Serum TSH With Renal Plasma Flow. J Clin Endocrinol Metab. 2021 08 18; 106(9):e3327-e3334.
    View in: PubMed
    Score: 0.238
  5. Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design. Pharmacogenet Genomics. 2021 06 01; 31(4):83-88.
    View in: PubMed
    Score: 0.235
  6. Interplay Between Statins, Cav1 (Caveolin-1), and Aldosterone. Hypertension. 2020 09; 76(3):962-967.
    View in: PubMed
    Score: 0.222
  7. Striatin heterozygous mice are more sensitive to aldosterone-induced injury. J Endocrinol. 2020 06; 245(3):439-450.
    View in: PubMed
    Score: 0.219
  8. mTORC1 Deficiency Modifies Volume Homeostatic Responses to Dietary Sodium in a Sex-Specific Manner. Endocrinology. 2020 05 01; 161(5).
    View in: PubMed
    Score: 0.218
  9. Higher urinary cortisol levels associate with increased cardiovascular risk. Endocr Connect. 2019 Jun 01; 8(6):634-640.
    View in: PubMed
    Score: 0.204
  10. Aldosterone Modulates the Mechanistic Target of Rapamycin Signaling in Male Mice. Endocrinology. 2019 04 01; 160(4):716-728.
    View in: PubMed
    Score: 0.202
  11. Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production. J Endocrinol. 2019 02 01; 240(2):111-122.
    View in: PubMed
    Score: 0.200
  12. Dysregulated aldosterone secretion in persons of African descent with endothelin-1 gene variants. JCI Insight. 2017 12 07; 2(23).
    View in: PubMed
    Score: 0.185
  13. Regulation of aldosterone secretion by mineralocorticoid receptor-mediated signaling. J Endocrinol. 2017 03; 232(3):525-534.
    View in: PubMed
    Score: 0.174
  14. Response to Letter Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects". Circulation. 2016 Apr 19; 133(16):e606.
    View in: PubMed
    Score: 0.165
  15. Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects. Circulation. 2015 Nov 10; 132(19):1825-33.
    View in: PubMed
    Score: 0.159
  16. Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans. Hypertension. 2015 Jan; 65(1):211-217.
    View in: PubMed
    Score: 0.149
  17. Sodium restriction increases aldosterone biosynthesis by increasing late pathway, but not early pathway, messenger ribonucleic acid levels and enzyme activity in normotensive rats. Endocrinology. 1993 Nov; 133(5):2235-40.
    View in: PubMed
    Score: 0.139
  18. Abnormal aldosterone physiology and cardiometabolic risk factors. Hypertension. 2013 Apr; 61(4):886-93.
    View in: PubMed
    Score: 0.132
  19. Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake. Age (Dordr). 2013 Oct; 35(5):1809-20.
    View in: PubMed
    Score: 0.129
  20. Effect of low dose mineralocorticoid receptor antagonist eplerenone on glucose and lipid metabolism in healthy adult males. Metabolism. 2013 Mar; 62(3):386-91.
    View in: PubMed
    Score: 0.129
  21. Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2012 Oct; 97(10):3775-82.
    View in: PubMed
    Score: 0.127
  22. Replication and meta-analysis of the gene-environment interaction between body mass index and the interleukin-6 promoter polymorphism with higher insulin resistance. Metabolism. 2012 May; 61(5):667-71.
    View in: PubMed
    Score: 0.121
  23. Dietary sodium intake regulates angiotensin II type 1, mineralocorticoid receptor, and associated signaling proteins in heart. J Endocrinol. 2011 Oct; 211(1):47-54.
    View in: PubMed
    Score: 0.118
  24. Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension. J Clin Endocrinol Metab. 2011 Aug; 96(8):E1288-92.
    View in: PubMed
    Score: 0.117
  25. Cell membrane-associated mineralocorticoid receptors? New evidence. Hypertension. 2011 Jun; 57(6):1019-25.
    View in: PubMed
    Score: 0.116
  26. The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach. Metabolism. 2011 Aug; 60(8):1150-7.
    View in: PubMed
    Score: 0.115
  27. Low-salt diet increases insulin resistance in healthy subjects. Metabolism. 2011 Jul; 60(7):965-8.
    View in: PubMed
    Score: 0.113
  28. The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study. J Clin Endocrinol Metab. 2010 Sep; 95(9):E75-9.
    View in: PubMed
    Score: 0.110
  29. Aldosterone production and insulin resistance in healthy adults. J Clin Endocrinol Metab. 2010 Apr; 95(4):1986-90.
    View in: PubMed
    Score: 0.107
  30. Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II. Endocrinology. 2010 Mar; 151(3):1236-46.
    View in: PubMed
    Score: 0.107
  31. Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats. J Endocrinol. 2009 Jan; 200(1):75-84.
    View in: PubMed
    Score: 0.098
  32. Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammatory adipokines. Circulation. 2008 Apr 29; 117(17):2253-61.
    View in: PubMed
    Score: 0.095
  33. Changes in adrenal responsiveness and potassium balance with shifts in sodium intake. Endocr Res. 1987; 13(4):419-45.
    View in: PubMed
    Score: 0.086
  34. Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Endocrinology. 2006 Nov; 147(11):5363-73.
    View in: PubMed
    Score: 0.084
  35. Effect of acute aldosterone administration on gene expression profile in the heart. Endocrinology. 2006 Jul; 147(7):3183-9.
    View in: PubMed
    Score: 0.082
  36. Cardiac damage prevention by eplerenone: comparison with low sodium diet or potassium loading. Hypertension. 2002 Feb; 39(2 Pt 2):614-8.
    View in: PubMed
    Score: 0.062
  37. Aldosterone: a mediator of myocardial necrosis and renal arteriopathy. Endocrinology. 2000 Oct; 141(10):3871-8.
    View in: PubMed
    Score: 0.056
  38. A clinical trial to evaluate the effect of statin use on lowering aldosterone levels. BMC Endocr Disord. 2020 Jul 14; 20(1):105.
    View in: PubMed
    Score: 0.055
  39. Sex-specific differences in endoplasmic reticulum aminopeptidase 1 modulation influence blood pressure and renin-angiotensin system responses. JCI Insight. 2019 11 01; 4(21).
    View in: PubMed
    Score: 0.053
  40. Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II. Hypertension. 2018 06; 71(6):1083-1090.
    View in: PubMed
    Score: 0.047
  41. Caloric restriction improves glucose homeostasis, yet increases cardiometabolic risk in caveolin-1-deficient mice. Metabolism. 2018 06; 83:92-101.
    View in: PubMed
    Score: 0.047
  42. Combined Salt and Caloric Restrictions: Potential Adverse Outcomes. J Am Heart Assoc. 2017 Oct 11; 6(10).
    View in: PubMed
    Score: 0.046
  43. Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis. J Am Heart Assoc. 2016 09 28; 5(10).
    View in: PubMed
    Score: 0.042
  44. A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics. Metabolism. 2015 Dec; 64(12):1674-81.
    View in: PubMed
    Score: 0.040
  45. Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury. J Pharmacol Exp Ther. 2015 Oct; 355(1):32-47.
    View in: PubMed
    Score: 0.039
  46. Critical Role of Striatin in Blood Pressure and Vascular Responses to Dietary Sodium Intake. Hypertension. 2015 Sep; 66(3):674-80.
    View in: PubMed
    Score: 0.039
  47. Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function. Endocrinology. 2014 Nov; 155(11):4461-72.
    View in: PubMed
    Score: 0.037
  48. Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk. Hypertension. 2014 Jun; 63(6):1205-11.
    View in: PubMed
    Score: 0.036
  49. Aldosterone's rapid, nongenomic effects are mediated by striatin: a modulator of aldosterone's effect on estrogen action. Endocrinology. 2014 Jun; 155(6):2233-43.
    View in: PubMed
    Score: 0.036
  50. Dissociation of hyperglycemia from altered vascular contraction and relaxation mechanisms in caveolin-1 null mice. J Pharmacol Exp Ther. 2014 Feb; 348(2):260-70.
    View in: PubMed
    Score: 0.035
  51. Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone. Hypertension. 2014 Feb; 63(2):273-80.
    View in: PubMed
    Score: 0.035
  52. Direct renin inhibition modulates insulin resistance in caveolin-1-deficient mice. Metabolism. 2013 Feb; 62(2):275-81.
    View in: PubMed
    Score: 0.032
  53. Dose effect of adrenocorticotropin on aldosterone and cortisol biosynthesis in cultured bovine adrenal glomerulosa cells: in vitro correlate of hyperreninemic hypoaldosteronism. Endocrinology. 1992 Jul; 131(1):187-94.
    View in: PubMed
    Score: 0.032
  54. Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. Am J Hypertens. 2012 Jul; 25(7):812-7.
    View in: PubMed
    Score: 0.031
  55. Activation of the mineralocorticoid receptor increases striatin levels. Am J Hypertens. 2012 Feb; 25(2):243-9.
    View in: PubMed
    Score: 0.030
  56. Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension. Am J Physiol Heart Circ Physiol. 2011 Nov; 301(5):H1862-71.
    View in: PubMed
    Score: 0.030
  57. Mineralocorticoid receptor expression in human venous smooth muscle cells: a potential role for aldosterone signaling in vein graft arterialization. Am J Physiol Heart Circ Physiol. 2011 Jul; 301(1):H41-7.
    View in: PubMed
    Score: 0.029
  58. Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H1776-88.
    View in: PubMed
    Score: 0.027
  59. Effect of dietary sodium on vasoconstriction and eNOS-mediated vascular relaxation in caveolin-1-deficient mice. Am J Physiol Heart Circ Physiol. 2008 Mar; 294(3):H1258-65.
    View in: PubMed
    Score: 0.023
  60. Body mass index predicts aldosterone production in normotensive adults on a high-salt diet. J Clin Endocrinol Metab. 2007 Nov; 92(11):4472-5.
    View in: PubMed
    Score: 0.023
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.