Bradley Theodore Hyman, M.D., Ph.D.
This page shows the publications co-authored by Bradley Hyman and Sudeshna Das.
Differential gene expression data from the human central nervous system across Alzheimer's disease, Lewy body diseases, and the amyotrophic lateral sclerosis and frontotemporal dementia spectrum. Data Brief. 2021 Apr; 35:106863.
APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches. Lancet Neurol. 2021 01; 20(1):68-80.
Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration. Neurobiol Dis. 2021 02; 149:105225.
Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration. J Neuroinflammation. 2020 Jul 31; 17(1):227.
Characterizing Clinical and Neuropathological Traits of APOE Haplotypes in African Americans and Europeans. J Alzheimers Dis. 2020; 78(1):467-477.
Novel methods for integration and visualization of genomics and genetics data in Alzheimer's disease. Alzheimers Dement. 2019 06; 15(6):788-798.
Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease. Proc Natl Acad Sci U S A. 2018 02 06; 115(6):E1289-E1298.
Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease. Neuropathol Appl Neurobiol. 2021 Jul 23.
Visit-to-Visit Blood Pressure Variability, Neuropathology, and Cognitive Decline. Neurology. 2021 06 08; 96(23):e2812-e2823.
Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics. Neurobiol Aging. 2021 09; 105:99-114.
Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. Front Neurol. 2020; 11:575953.
Characterization of the 18 kDa translocator protein (TSPO) expression in post-mortem normal and Alzheimer's disease brains. Brain Pathol. 2020 01; 30(1):151-164.
The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aß Plaques. Cell Rep. 2019 04 23; 27(4):1293-1306.e6.
Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain. J Neurochem. 2018 10; 147(1):24-39.
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