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Michael Hayden Rosenthal, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Griffin GK, Weirather JL, Roemer MGM, Lipschitz M, Kelley A, Chen PH, Gusenleitner D, Jeter E, Pak C, Gjini E, Chapuy B, Rosenthal MH, Xu J, Chen BJ, Sohani AR, Lovitch SB, Abramson JS, Ishizuka JJ, Kim AI, Jacobson CA, LaCasce AS, Fletcher CD, Neuberg D, Freeman GJ, Hodi FS, Wright K, Ligon AH, Jacobsen ED, Armand P, Shipp MA, Rodig SJ. Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma. Blood. 2021 Mar 11; 137(10):1353-1364. PMID: 32871584.
    Citations: 2     Fields:    
  2. Kenner B, Chari ST, Kelsen D, Klimstra DS, Pandol SJ, Rosenthal M, Rustgi AK, Taylor JA, Yala A, Abul-Husn N, Andersen DK, Bernstein D, Brunak S, Canto MI, Eldar YC, Fishman EK, Fleshman J, Go VLW, Holt JM, Field B, Goldberg A, Hoos W, Iacobuzio-Donahue C, Li D, Lidgard G, Maitra A, Matrisian LM, Poblete S, Rothschild L, Sander C, Schwartz LH, Shalit U, Srivastava S, Wolpin B. Artificial Intelligence and Early Detection of Pancreatic Cancer: 2020 Summative Review. Pancreas. 2021 Mar 01; 50(3):251-279. PMID: 33835956.
    Citations:    Fields:    
  3. van Seventer E, Marquardt JP, Troschel AS, Best TD, Horick N, Azoba C, Newcomb R, Roeland EJ, Rosenthal M, Bridge CP, Greer JA, El-Jawahri A, Temel J, Fintelmann FJ, Nipp RD. Associations of Skeletal Muscle With Symptom Burden and Clinical Outcomes in Hospitalized Patients With Advanced Cancer. J Natl Compr Canc Netw. 2021 01 29; 1-9. PMID: 33513564.
    Citations:    Fields:    
  4. Zaid M, Elganainy D, Dogra P, Dai A, Widmann L, Fernandes P, Wang Z, Pelaez MJ, Ramirez JR, Singhi AD, Dasyam AK, Brand RE, Park WG, Rahmanuddin S, Rosenthal MH, Wolpin BM, Khalaf N, Goel A, Von Hoff DD, Tamm EP, Maitra A, Cristini V, Koay EJ. Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection. Front Oncol. 2020; 10:596931. PMID: 33344245.
    Citations: 1     
  5. Magudia K, Bridge CP, Bay CP, Babic A, Fintelmann FJ, Troschel FM, Miskin N, Wrobel WC, Brais LK, Andriole KP, Wolpin BM, Rosenthal MH. Population-Scale CT-based Body Composition Analysis of a Large Outpatient Population Using Deep Learning to Derive Age-, Sex-, and Race-specific Reference Curves. Radiology. 2021 02; 298(2):319-329. PMID: 33231527.
    Citations: 1     Fields:    Translation:Humans
  6. Brown JC, Rosenthal MH, Ma C, Zhang S, Nimeiri HS, McCleary NJ, Abrams TA, Yurgelun MB, Cleary JM, Rubinson DA, Schrag D, Bullock AJ, Allen J, Zuckerman D, Chan E, Chan JA, Wolpin B, Constantine M, Weckstein DJ, Faggen MA, Thomas CA, Kournioti C, Yuan C, Zheng H, Hollis BW, Fuchs CS, Ng K, Meyerhardt JA. Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Body Composition among Patients with Advanced or Metastatic Colorectal Cancer: A Randomized Trial. Cancers (Basel). 2020 Nov 20; 12(11). PMID: 33233566.
    Citations:    
  7. Yuan C, Babic A, Khalaf N, Nowak JA, Brais LK, Rubinson DA, Ng K, Aguirre AJ, Pandharipande PV, Fuchs CS, Giovannucci EL, Stampfer MJ, Rosenthal MH, Sander C, Kraft P, Wolpin BM. Diabetes, Weight Change, and Pancreatic Cancer Risk. JAMA Oncol. 2020 10 01; 6(10):e202948. PMID: 32789511.
    Citations: 2     Fields:    Translation:Humans
  8. Chawla A, Molina G, Pak LM, Rosenthal M, Mancias JD, Clancy TE, Wolpin BM, Wang J. Neoadjuvant Therapy is Associated with Improved Survival in Borderline-Resectable Pancreatic Cancer. Ann Surg Oncol. 2020 Apr; 27(4):1191-1200. PMID: 31802297.
    Citations: 4     Fields:    Translation:Humans
  9. Thomas R, Shinagare AB, Rosenthal MH, Lee B, Jacene HA, Johnston MA, Overmoyer BA. Computed tomographic assessment of lean body mass in patients on selective androgen receptor modulator. Clin Imaging. 2020 02; 59(2):100-103. PMID: 31812880.
    Citations:    Fields:    
  10. Hope TA, Gollub MJ, Arya S, Bates DDB, Ganeshan D, Harisinghani M, Jhaveri KS, Kassam Z, Kim DH, Korngold E, Lalwani N, Moreno CC, Nougaret S, Paroder V, Paspulati RM, Golia Pernicka JS, Petkovska I, Pickhardt PJ, Rauch GM, Rosenthal MH, Sheedy SP, Horvat N. Rectal cancer lexicon: consensus statement from the society of abdominal radiology rectal & anal cancer disease-focused panel. Abdom Radiol (NY). 2019 11; 44(11):3508-3517. PMID: 31388697.
    Citations: 1     Fields:    Translation:Humans
  11. Gollub MJ, Lall C, Lalwani N, Rosenthal MH. Current controversy, confusion, and imprecision in the use and interpretation of rectal MRI. Abdom Radiol (NY). 2019 11; 44(11):3549-3558. PMID: 31062058.
    Citations:    Fields:    Translation:Humans
  12. Babic A, Rosenthal MH, Bamlet WR, Takahashi N, Sugimoto M, Danai LV, Morales-Oyarvide V, Khalaf N, Dunne RF, Brais LK, Welch MW, Zellers CL, Dennis C, Rifai N, Prado CM, Caan B, Sundaresan TK, Meyerhardt JA, Kulke MH, Clish CB, Ng K, Vander Heiden MG, Petersen GM, Wolpin BM. Postdiagnosis Loss of Skeletal Muscle, but Not Adipose Tissue, Is Associated with Shorter Survival of Patients with Advanced Pancreatic Cancer. Cancer Epidemiol Biomarkers Prev. 2019 12; 28(12):2062-2069. PMID: 31533940.
    Citations: 5     Fields:    Translation:Humans
  13. Alessandrino F, Qin L, Cruz G, Sahu S, Rosenthal MH, Meyerhardt JA, Shinagare AB. 5-Fluorouracil induced liver toxicity in patients with colorectal cancer: role of computed tomography texture analysis as a potential biomarker. Abdom Radiol (NY). 2019 09; 44(9):3099-3106. PMID: 31250179.
    Citations:    Fields:    Translation:Humans
  14. Gurjao C, Liu D, Hofree M, AlDubayan SH, Wakiro I, Su MJ, Felt K, Gjini E, Brais LK, Rotem A, Rosenthal MH, Rozenblatt-Rosen O, Rodig S, Ng K, Van Allen EM, Corsello SM, Ogino S, Regev A, Nowak JA, Giannakis M. Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair-Deficient Colorectal Cancer. Cancer Immunol Res. 2019 08; 7(8):1230-1236. PMID: 31217164.
    Citations: 14     Fields:    Translation:HumansCells
  15. Howard SA, Rosenthal MH, Qin L, Matalon SA, Bernard BD, Beard CJ, Sweeney CJ. Quantifying Decreased Radiation Exposure From Modern CT Scan Technology and Surveillance Programs of Germ Cell Tumors. Am J Clin Oncol. 2018 10; 41(10):949-952. PMID: 28654572.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  16. Chawla A, Rosenthal MH, Clancy TE. Implications of the replaced right hepatic artery originating from the gastroduodenal artery in the setting of a pancreatic head mass. Clin Imaging. 2018 Nov - Dec; 52:189-192. PMID: 30103107.
    Citations:    Fields:    Translation:Humans
  17. Danai LV, Babic A, Rosenthal MH, Dennstedt EA, Muir A, Lien EC, Mayers JR, Tai K, Lau AN, Jones-Sali P, Prado CM, Petersen GM, Takahashi N, Sugimoto M, Yeh JJ, Lopez N, Bardeesy N, Fernandez-Del Castillo C, Liss AS, Koong AC, Bui J, Yuan C, Welch MW, Brais LK, Kulke MH, Dennis C, Clish CB, Wolpin BM, Vander Heiden MG. Altered exocrine function can drive adipose wasting in early pancreatic cancer. Nature. 2018 06; 558(7711):600-604. PMID: 29925948.
    Citations: 38     Fields:    Translation:Animals
  18. Aguirre AJ, Nowak JA, Camarda ND, Moffitt RA, Ghazani AA, Hazar-Rethinam M, Raghavan S, Kim J, Brais LK, Ragon D, Welch MW, Reilly E, McCabe D, Marini L, Anderka K, Helvie K, Oliver N, Babic A, Da Silva A, Nadres B, Van Seventer EE, Shahzade HA, St Pierre JP, Burke KP, Clancy T, Cleary JM, Doyle LA, Jajoo K, McCleary NJ, Meyerhardt JA, Murphy JE, Ng K, Patel AK, Perez K, Rosenthal MH, Rubinson DA, Ryou M, Shapiro GI, Sicinska E, Silverman SG, Nagy RJ, Lanman RB, Knoerzer D, Welsch DJ, Yurgelun MB, Fuchs CS, Garraway LA, Getz G, Hornick JL, Johnson BE, Kulke MH, Mayer RJ, Miller JW, Shyn PB, Tuveson DA, Wagle N, Yeh JJ, Hahn WC, Corcoran RB, Carter SL, Wolpin BM. Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine. Cancer Discov. 2018 09; 8(9):1096-1111. PMID: 29903880.
    Citations: 48     Fields:    Translation:HumansCells
  19. Thomas R, Rosenthal MH, Ghouri M, Steigner ML. Infundibulum of the common origin of fourth lumbar arteries and median sacral artery. J Med Imaging Radiat Oncol. 2018 Mar 24. PMID: 29573579.
    Citations:    Fields:    
  20. Richman DM, Tirumani SH, Hornick JL, Fuchs CS, Howard S, Krajewski K, Ramaiya N, Rosenthal M. Beyond gastric adenocarcinoma: Multimodality assessment of common and uncommon gastric neoplasms. Abdom Radiol (NY). 2017 01; 42(1):124-140. PMID: 27645897.
    Citations: 14     Fields:    Translation:Humans
  21. Perez K, Clancy TE, Mancias JD, Rosenthal MH, Wolpin BM. When, What, and Why of Perioperative Treatment of Potentially Curable Pancreatic Adenocarcinoma. J Clin Oncol. 2017 Feb 10; 35(5):485-489. PMID: 28029328.
    Citations: 4     Fields:    Translation:Humans
  22. Wortman JR, Tirumani SH, Jagannathan JP, Rosenthal MH, Shinagare AB, Hornick JL, Baldini EH, Ramaiya NH. Radiation Therapy for Soft-Tissue Sarcomas: A Primer for Radiologists. Radiographics. 2016 Mar-Apr; 36(2):554-72. PMID: 26963462.
    Citations: 3     Fields:    Translation:Humans
  23. Matalon SA, Mamon HJ, Fuchs CS, Doyle LA, Tirumani SH, Ramaiya NH, Rosenthal MH. Anorectal Cancer: Critical Anatomic and Staging Distinctions That Affect Use of Radiation Therapy. Radiographics. 2015 Nov-Dec; 35(7):2090-107. PMID: 26562239.
    Citations: 10     Fields:    Translation:HumansCells
  24. Keraliya AR, Rosenthal MH, Krajewski KM, Jagannathan JP, Shinagare AB, Tirumani SH, Ramaiya NH. Imaging of Fluid in Cancer Patients Treated With Systemic Therapy: Chemotherapy, Molecular Targeted Therapy, and Hematopoietic Stem Cell Transplantation. AJR Am J Roentgenol. 2015 Oct; 205(4):709-19. PMID: 26397319.
    Citations: 1     Fields:    Translation:Humans
  25. Sharmeen F, Rosenthal MH, Wood MJ, Tirumani SH, Sweeney C, Howard SA. Relationship Between the Pathologic Subtype/Initial Stage and Microliths in Testicular Germ Cell Tumors. J Ultrasound Med. 2015 Nov; 34(11):1977-82. PMID: 26396167.
    Citations: 4     Fields:    Translation:Humans
  26. Rosenthal MH, Lee A, Jajoo K. Imaging and Endoscopic Approaches to Pancreatic Cancer. Hematol Oncol Clin North Am. 2015 Aug; 29(4):675-99. PMID: 26226904.
    Citations:    Fields:    Translation:Humans
  27. Fairchild A, Tirumani SH, Rosenthal MH, Howard SA, Krajewski KM, Nishino M, Shinagare AB, Jagannathan JP, Ramaiya NH. Hormonal therapy in oncology: a primer for the radiologist. AJR Am J Roentgenol. 2015 Jun; 204(6):W620-30. PMID: 26001251.
    Citations: 4     Fields:    Translation:Humans
  28. Suh CH, Tirumani SH, Shinagare AB, Kim KW, Rosenthal MH, Ramaiya NH, Baheti AD. Diagnosis and management of duodenal adenocarcinomas: a comprehensive review for the radiologist. Abdom Imaging. 2015 Jun; 40(5):1110-20. PMID: 25427987.
    Citations: 2     Fields:    Translation:Humans
  29. Rosenthal MH, Kim KW, Fuchs CS, Meyerhardt JA, Ramaiya NH. CT predictors of overall survival at initial diagnosis in patients with stage IV colorectal cancer. Abdom Imaging. 2015 Jun; 40(5):1170-6. PMID: 25326260.
    Citations: 2     Fields:    Translation:Humans
  30. Tirumani SH, Shinagare AB, O'Neill AC, Nishino M, Rosenthal MH, Ramaiya NH. Accuracy and feasibility of estimated tumour volumetry in primary gastric gastrointestinal stromal tumours: validation using semiautomated technique in 127 patients. Eur Radiol. 2016 Jan; 26(1):286-95. PMID: 25991487.
    Citations: 8     Fields:    Translation:Humans
  31. Howard SA, Rosenthal MH, Jagannathan JP, Krajewski KM, Shinagare AB, Ramaiya NH, Tirumani SH. Beyond the vascular endothelial growth factor axis: update on role of imaging in nonantiangiogenic molecular targeted therapies in oncology. AJR Am J Roentgenol. 2015 May; 204(5):919-32. PMID: 25905926.
    Citations: 1     Fields:    Translation:Humans
  32. Tirumani H, Rosenthal MH, Tirumani SH, Shinagare AB, Krajewski KM, Ramaiya NH. Esophageal Carcinoma: Current Concepts in the Role of Imaging in Staging and Management. Can Assoc Radiol J. 2015 May; 66(2):130-9. PMID: 25770628.
    Citations: 6     Fields:    Translation:Humans
  33. Tirumani SH, Fairchild A, Krajewski KM, Nishino M, Howard SA, Baheti AD, Rosenthal MH, Jagannathan JP, Shinagare AB, Ramaiya NH. Anti-VEGF molecular targeted therapies in common solid malignancies: comprehensive update for radiologists. Radiographics. 2015 Mar-Apr; 35(2):455-74. PMID: 25763729.
    Citations: 7     Fields:    Translation:Humans
  34. Richman DM, Bresler SC, Rosenthal MH, Howard SA. Malignant tenosynovial giant cell tumor of the leg: a radiologic-pathologic correlation and review of the literature. J Clin Imaging Sci. 2015; 5:13. PMID: 25861547.
    Citations: 2     
  35. Hill AJ, Tirumani SH, Rosenthal MH, Shinagare AB, Carrasco RD, Munshi NC, Ramaiya NH, Howard SA. Multimodality imaging and clinical features in Castleman disease: single institute experience in 30 patients. Br J Radiol. 2015 May; 88(1049):20140670. PMID: 25710283.
    Citations: 13     Fields:    Translation:Humans
  36. Baheti AD, Tirumani SH, Rosenthal MH, Howard SA, Shinagare AB, Ramaiya NH, Jagannathan JP. Myxoid soft-tissue neoplasms: comprehensive update of the taxonomy and MRI features. AJR Am J Roentgenol. 2015 Feb; 204(2):374-85. PMID: 25615761.
    Citations: 14     Fields:    Translation:Humans
  37. Baheti AD, Tirumani SH, Giardino A, Rosenthal MH, Tirumani H, Krajewski K, Ramaiya NH. Basal cell carcinoma: a comprehensive review for the radiologist. AJR Am J Roentgenol. 2015 Feb; 204(2):W132-40. PMID: 25615773.
    Citations: 3     Fields:    Translation:Humans
  38. Suh CH, Baheti AD, Tirumani SH, Rosenthal MH, Kim KW, Ramaiya NH, Shinagare AB. Multimodality imaging of penile cancer: what radiologists need to know. Abdom Imaging. 2015 Feb; 40(2):424-35. PMID: 25117563.
    Citations:    Fields:    Translation:Humans
  39. Baheti AD, Tirumani SH, Shinagare AB, Rosenthal MH, Hornick JL, Ramaiya NH, Wolpin BM. Correlation of CT patterns of primary intrahepatic cholangiocarcinoma at the time of presentation with the metastatic spread and clinical outcomes: retrospective study of 92 patients. Abdom Imaging. 2014 Dec; 39(6):1193-201. PMID: 24869789.
    Citations: 7     Fields:    Translation:Humans
  40. Rohatgi S, Jagannathan JP, Rosenthal MH, Kim KW, Ramaiya NH, Krajewski KM. Vascular toxicity associated with chemotherapy and molecular targeted therapy: what should a radiologist know? AJR Am J Roentgenol. 2014 Dec; 203(6):1353-62. PMID: 25415715.
    Citations: 5     Fields:    Translation:Humans
  41. Rosenthal MH, Kim KW, Fuchs CS, Meyerhardt JA, Ramaiya NH. Relationships between KRAS mutation status and baseline radiographic distribution of disease in patients with stage IV colorectal cancer. Abdom Imaging. 2014 Dec; 39(6):1261-6. PMID: 24906690.
    Citations: 1     Fields:    Translation:Humans
  42. O'Neill AC, Shinagare AB, Rosenthal MH, Tirumani SH, Jagannathan JP, Ramaiya NH. Differences in CT features of peritoneal carcinomatosis, sarcomatosis, and lymphomatosis: retrospective analysis of 122 cases at a tertiary cancer institution. Clin Radiol. 2014 Dec; 69(12):1219-27. PMID: 25308238.
    Citations: 3     Fields:    Translation:Humans
  43. Baheti AD, Tirumani SH, Rosenthal MH, Shinagare AB, Ramaiya NH. Diagnosis and management of intrahepatic cholangiocarcinoma: a comprehensive update for the radiologist. Clin Radiol. 2014 Dec; 69(12):e463-70. PMID: 25240565.
    Citations: 6     Fields:    Translation:Humans
  44. Shah SM, Rosenthal MH, Griffin GK, Jacobsen ED, McCleary NJ. An aggressive presentation of colorectal cancer with an atypical lymphoproliferative pattern of metastatic disease: a case report and review of the literature. Clin Colorectal Cancer. 2014 Sep; 13(3):e5-e11. PMID: 25065654.
    Citations: 5     Fields:    Translation:Humans
  45. Cabral FC, Krajewski KM, Rosenthal MH, Hirsch MS, Howard SA. Teratoma with malignant transformation: report of three cases and review of the literature. Clin Imaging. 2014 Sep-Oct; 38(5):589-93. PMID: 24908364.
    Citations: 7     Fields:    Translation:Humans
  46. Somarouthu BS, Shinagare AB, Rosenthal MH, Tirumani H, Hornick JL, Ramaiya NH, Tirumani SH. Multimodality imaging features, metastatic pattern and clinical outcome in adult extraskeletal Ewing sarcoma: experience in 26 patients. Br J Radiol. 2014 Jun; 87(1038):20140123. PMID: 24734938.
    Citations: 7     Fields:    Translation:Humans
  47. Tirumani H, Rosenthal MH, Tirumani SH, Shinagare AB, Krajewski KM, Ramaiya NH. Imaging of uncommon esophageal malignancies. Dis Esophagus. 2015 Aug-Sep; 28(6):552-9. PMID: 24635682.
    Citations: 3     Fields:    Translation:Humans
  48. Sharmeen F, Rosenthal MH, Howard SA. The management of retroperitoneal lymphadenopathy in spermatocytic seminoma of the testicle. Clin Imaging. 2014 Mar-Apr; 38(2):202-4. PMID: 24361173.
    Citations: 1     Fields:    Translation:HumansCells
  49. Burke CT, Cullen JM, State A, Gadi S, Wilber K, Rosenthal M, Bulysheva A, Pease A, Mauro MA, Fuchs H. Development of an animal model for radiofrequency ablation of primary, virally induced hepatocellular carcinoma in the woodchuck. J Vasc Interv Radiol. 2011 Nov; 22(11):1613-1618.e1. PMID: 21959057.
    Citations: 6     Fields:    Translation:AnimalsCells
  50. Fortson JK, Brown J, Patel VG, Lawrence GE, Rosenthal M. Pathologic fracture of the femur as a presenting sign of metastatic follicular carcinoma of the thyroid. Am Surg. 2010 Aug; 76(8):E137-8. PMID: 21513636.
    Citations:    Fields:    Translation:Humans
  51. Rosenthal M, Young Kim H, Lee KS. Some morphologic features may differentiate nodular ground-glass opacities: statistical review. Radiology. 2008 Apr; 247(1):296; author reply 296. PMID: 18372478.
    Citations:    Fields:    Translation:Humans
  52. Fuchs H, State A, Yang H, Peck T, Lee SW, Rosenthal M, Bulysheva A, Burke C. Optimizing a head-tracked stereo display system to guide hepatic tumor ablation. Stud Health Technol Inform. 2008; 132:126-31. PMID: 18391272.
    Citations: 1     Fields:    Translation:Humans
  53. Myers RE, Sifri R, Hyslop T, Rosenthal M, Vernon SW, Cocroft J, Wolf T, Andrel J, Wender R. A randomized controlled trial of the impact of targeted and tailored interventions on colorectal cancer screening. Cancer. 2007 Nov 01; 110(9):2083-91. PMID: 17893869.
    Citations: 107     Fields:    Translation:HumansPHPublic Health
  54. State A, Keller K, Rosenthal M, Yang H, Ackerman J, Fuchs H. Stereo imagery from the UNC augmented reality system for breast biopsy guidance. Stud Health Technol Inform. 2003; 94:325-8. PMID: 15455917.
    Citations: 1     Fields:    
  55. Rosenthal M, State A, Lee J, Hirota G, Ackerman J, Keller K, Pisano E, Jiroutek M, Muller K, Fuchs H. Augmented reality guidance for needle biopsies: an initial randomized, controlled trial in phantoms. Med Image Anal. 2002 Sep; 6(3):313-20. PMID: 12270235.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  56. Rosenthal M, Jacobson F, Silverman S. Understanding Perfusion Imaging: How Is It Done and How Can It Be Used? Radiological Society of North America Annual Meeting, Chicago, IL. November 28 - December 3, 2010.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.