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Michael Mannstadt, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK100584 (MANNSTADT, MICHAEL) Jan 1, 2014 - Oct 31, 2019
    NIH
    Mode of Action of GCM2, the Essential Parathyroid Transcription Factor
    Role: Principal Investigator
  2. K08DK081669 (MANNSTADT, MICHAEL) Jul 15, 2008 - Jun 30, 2013
    NIH
    Dominant-negative GCMB mutations cause hypoparathyroidism
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Silver Karcioglu AL, Triponez F, Solórzano CC, Iwata AJ, Abdelhamid Ahmed AH, Almquist M, Angelos P, Benmiloud F, Berber E, Bergenfelz A, Cha J, Colaianni CA, Davies L, Duh QY, Hartl D, Kandil E, Kim WW, Kopp PA, Liddy W, Mahadevan-Jansen A, Lee KD, Mannstadt M, McMullen CP, Shonka DC, Shin JJ, Singer MC, Slough CM, Stack BC, Tearney G, Thomas G, Tolley N, Vidal-Fortuny J, Randolph GW. Emerging Imaging Technologies for Parathyroid Gland Identification and Vascular Assessment in Thyroid Surgery: A Review From the American Head and Neck Society Endocrine Surgery Section. JAMA Otolaryngol Head Neck Surg. 2023 Jan 12. PMID: 36633855.
    Citations:    Fields:    
  2. Yao L, Li J, Li M, Lin C, Hui X, Tamilselvan D, Kandi M, Sreekanta A, Makhdami N, Ali DS, Dandurand K, Yang K, Bilezikian JP, Brandi ML, Clarke BL, Mannstadt M, Rejnmark L, Khan AA, Guyatt G. Parathyroid Hormone Therapy for Managing Chronic Hypoparathyroidism: A Systematic Review and Meta-Analysis. J Bone Miner Res. 2022 12; 37(12):2654-2662. PMID: 36385517.
    Citations:    Fields:    Translation:Humans
  3. Mannstadt M, Cianferotti L, Gafni RI, Giusti F, Kemp EH, Koch CA, Roszko KL, Yao L, Guyatt GH, Thakker RV, Xia W, Brandi ML. Hypoparathyroidism: Genetics and Diagnosis. J Bone Miner Res. 2022 12; 37(12):2615-2629. PMID: 36375809.
    Citations:    Fields:    Translation:Humans
  4. Khan AA, Bilezikian JP, Brandi ML, Clarke BL, Potts JJ, Mannstadt M. The Second International Workshop on the Evaluation and Management of Hypoparathyroidism. J Bone Miner Res. 2022 12; 37(12):2566-2567. PMID: 36375811.
    Citations:    Fields:    Translation:Humans
  5. Yao L, Hui X, Li M, Li J, Ahmed MM, Lin C, Kandi M, Sreekanta A, Makhdami N, Tamilselvan D, Ali DS, Dandurand K, Yang K, Bilezikian JP, Brandi ML, Clarke BL, Mannstadt M, Rejnmark L, Khan AA, Guyatt G. Complications, Symptoms, Presurgical Predictors in Patients With Chronic Hypoparathyroidism: A Systematic Review. J Bone Miner Res. 2022 12; 37(12):2642-2653. PMID: 36375810.
    Citations:    Fields:    Translation:Humans
  6. Van Uum S, Shrayyef M, M'Hiri I, Dandurand K, Ali DS, Bilezikian JP, Collins MT, Mannstadt M, Rubin MR, Siggelkow H, Tabacco G, Tay YD, Vokes T, Winer KK, Yao L, Guyatt G, Rejnmark L, Khan AA. Initial Assessment and Monitoring of Patients with Chronic Hypoparathyroidism: A Systematic Current Practice Survey. J Bone Miner Res. 2022 12; 37(12):2630-2641. PMID: 36066096.
    Citations:    Fields:    Translation:Humans
  7. Khan AA, Bilezikian JP, Brandi ML, Clarke BL, Gittoes NJ, Pasieka JL, Rejnmark L, Shoback DM, Potts JT, Guyatt GH, Mannstadt M. Evaluation and Management of Hypoparathyroidism Summary Statement and Guidelines from the Second International Workshop. J Bone Miner Res. 2022 12; 37(12):2568-2585. PMID: 36054621.
    Citations:    Fields:    Translation:Humans
  8. Khan AA, Guyatt G, Ali DS, Bilezikian JP, Collins MT, Dandurand K, Mannstadt M, Murphy D, M'Hiri I, Rubin MR, Sanders R, Shrayyef M, Siggelkow H, Tabacco G, Tay YD, Van Uum S, Vokes T, Winer KK, Yao L, Rejnmark L. Management of Hypoparathyroidism. J Bone Miner Res. 2022 12; 37(12):2663-2677. PMID: 36161671.
    Citations:    Fields:    Translation:Humans
  9. Parksook WW, Heydarpour M, Brown JM, Turchin A, Mannstadt M, Vaidya A. Evaluating the clinical and mechanistic effects of eplerenone and amiloride monotherapy, and combination therapy with cinacalcet, in primary hyperparathyroidism: A placebo-controlled randomized trial. Clin Endocrinol (Oxf). 2022 Oct 31. PMID: 36316798.
    Citations:    Fields:    
  10. Bilezikian JP, Khan AA, Clarke BL, Mannstadt M, Potts JT, Brandi ML. The Fifth International Workshop on the Evaluation and Management of Primary Hyperparathyroidism. J Bone Miner Res. 2022 11; 37(11):2290-2292. PMID: 36245277.
    Citations: 1     Fields:    Translation:Humans
  11. Yao L, Guyatt G, Ye Z, Bilezikian JP, Brandi ML, Clarke BL, Mannstadt M, Khan AA. Methodology for the Guidelines on Evaluation and Management of Hypoparathyroidism and Primary Hyperparathyroidism. J Bone Miner Res. 2022 11; 37(11):2404-2410. PMID: 36053800.
    Citations:    Fields:    Translation:Humans
  12. Ye Z, Silverberg SJ, Sreekanta A, Tong K, Wang Y, Chang Y, Zhang M, Guyatt G, Tangamornsuksun W, Zhang Y, Manja V, Bakaa L, Couban RJ, Brandi ML, Clarke B, Khan AA, Mannstadt M, Bilezikian JP. The Efficacy and Safety of Medical and Surgical Therapy in Patients With Primary Hyperparathyroidism: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Bone Miner Res. 2022 11; 37(11):2351-2372. PMID: 36053960.
    Citations:    Fields:    Translation:Humans
  13. Bilezikian JP, Khan AA, Silverberg SJ, Fuleihan GE, Marcocci C, Minisola S, Perrier N, Sitges-Serra A, Thakker RV, Guyatt G, Mannstadt M, Potts JT, Clarke BL, Brandi ML. Evaluation and Management of Primary Hyperparathyroidism: Summary Statement and Guidelines from the Fifth International Workshop. J Bone Miner Res. 2022 11; 37(11):2293-2314. PMID: 36245251.
    Citations: 2     Fields:    Translation:Humans
  14. Meyer MB, Benkusky NA, Lee SM, Yoon SH, Mannstadt M, Wein MN, Pike JW. Rapid genomic changes by mineralotropic hormones and kinase SIK inhibition drive coordinated renal Cyp27b1 and Cyp24a1 expression via CREB modules. J Biol Chem. 2022 11; 298(11):102559. PMID: 36183832; PMCID: PMC9637672.
    Citations: 1     Fields:    Translation:Animals
  15. Swartling O, Evans M, Spelman T, Kamal W, Kämpe O, Mannstadt M, Trolle Lagerros Y, Björnsdottir S. Kidney Complications and Hospitalization in Patients With Chronic Hypoparathyroidism: A Cohort Study in Sweden. J Clin Endocrinol Metab. 2022 09 28; 107(10):e4098-e4105. PMID: 35907259; PMCID: PMC9516192.
    Citations:    Fields:    Translation:Humans
  16. Björnsdottir S, Clarke BL, Mannstadt M, Langdahl BL. Male osteoporosis-what are the causes, diagnostic challenges, and management. Best Pract Res Clin Rheumatol. 2022 Sep; 36(3):101766. PMID: 35961836.
    Citations:    Fields:    Translation:Humans
  17. Bondeson DP, Paolella BR, Asfaw A, Rothberg MV, Skipper TA, Langan C, Mesa G, Gonzalez A, Surface LE, Ito K, Kazachkova M, Colgan WN, Warren A, Dempster JM, Krill-Burger JM, Ericsson M, Tang AA, Fung I, Chambers ES, Abdusamad M, Dumont N, Doench JG, Piccioni F, Root DE, Boehm J, Hahn WC, Mannstadt M, McFarland JM, Vazquez F, Golub TR. Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. Nat Cancer. 2022 06; 3(6):681-695. PMID: 35437317; PMCID: PMC9246846.
    Citations:    Translation:Humans
  18. Gittoes N, Rejnmark L, Ing SW, Brandi ML, Björnsdottir S, Hahner S, Hofbauer LC, Houillier P, Khan AA, Levine MA, Mannstadt M, Shoback DM, Vokes TJ, Zhang P, Marelli C, Germak J, Clarke BL. The PARADIGHM (physicians advancing disease knowledge in hypoparathyroidism) registry for patients with chronic hypoparathyroidism: study protocol and interim baseline patient characteristics. BMC Endocr Disord. 2021 Nov 20; 21(1):232. PMID: 34801015; PMCID: PMC8606089.
    Citations:    Fields:    Translation:Humans
  19. Arnold A, Dennison E, Kovacs CS, Mannstadt M, Rizzoli R, Brandi ML, Clarke B, Thakker RV. Hormonal regulation of biomineralization. Nat Rev Endocrinol. 2021 05; 17(5):261-275. PMID: 33727709.
    Citations: 11     Fields:    Translation:HumansCells
  20. Ahn SV, Lee JH, Bove-Fenderson EA, Park SY, Mannstadt M, Lee S. Incidence of Hypoparathyroidism After Thyroid Cancer Surgery in South Korea, 2007-2016. JAMA. 2019 12 24; 322(24):2441-2443. PMID: 31860036; PMCID: PMC6990661.
    Citations: 6     Fields:    Translation:Humans
  21. Mannstadt M, Clarke BL, Bilezikian JP, Bone H, Denham D, Levine MA, Peacock M, Rothman J, Shoback DM, Warren ML, Watts NB, Lee HM, Sherry N, Vokes TJ. Safety and Efficacy of 5 Years of Treatment With Recombinant Human Parathyroid Hormone in Adults With Hypoparathyroidism. J Clin Endocrinol Metab. 2019 11 01; 104(11):5136-5147. PMID: 31369089; PMCID: PMC6760337.
    Citations: 11     Fields:    Translation:Humans
  22. Biebermann H, Kleinau G, Schnabel D, Bockenhauer D, Wilson LC, Tully I, Kiff S, Scheerer P, Reyes M, Paisdzior S, Gregory JW, Allgrove J, Krude H, Mannstadt M, Gardella TJ, Dattani M, Jüppner H, Grüters A. A New Multisystem Disorder Caused by the Gas Mutation p.F376V. J Clin Endocrinol Metab. 2019 04 01; 104(4):1079-1089. PMID: 30312418; PMCID: PMC6380466.
    Citations: 6     Fields:    Translation:Humans
  23. Haghighi A, Krier JB, Toth-Petroczy A, Cassa CA, Frank NY, Carmichael N, Fieg E, Bjonnes A, Mohanty A, Briere LC, Lincoln S, Lucia S, Gupta VA, Söylemez O, Sutti S, Kooshesh K, Qiu H, Fay CJ, Perroni V, Valerius J, Hanna M, Frank A, Ouahed J, Snapper SB, Pantazi A, Chopra SS, Leshchiner I, Stitziel NO, Feldweg A, Mannstadt M, Loscalzo J, Sweetser DA, Liao E, Stoler JM, Nowak CB, Sanchez-Lara PA, Klein OD, Perry H, Patsopoulos NA, Raychaudhuri S, Goessling W, Green RC, Seidman CE, MacRae CA, Sunyaev SR, Maas RL, Vuzman D. An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery. NPJ Genom Med. 2018; 3:21. PMID: 30131872; PMCID: PMC6089983.
    Citations: 6     
  24. Bove-Fenderson E, Mannstadt M. Hypocalcemic disorders. Best Pract Res Clin Endocrinol Metab. 2018 10; 32(5):639-656. PMID: 30449546.
    Citations: 9     Fields:    Translation:Humans
  25. Bove-Fenderson E, Duffy K, Mannstadt M. Sharing the Wealth: ASBMR Journals Update Policies on Data Sharing and Data Repositories. JBMR Plus. 2018 May; 2(3):119-120. PMID: 30283896; PMCID: PMC6124207.
    Citations:    
  26. Fan Y, Liu W, Bi R, Densmore MJ, Sato T, Mannstadt M, Yuan Q, Zhou X, Olauson H, Larsson TE, Toka HR, Pollak MR, Brown EM, Lanske B. Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3749-E3758. PMID: 29618612; PMCID: PMC5910831.
    Citations: 16     Fields:    Translation:Animals
  27. Goltzman D, Mannstadt M, Marcocci C. Physiology of the Calcium-Parathyroid Hormone-Vitamin D Axis. Front Horm Res. 2018; 50:1-13. PMID: 29597231.
    Citations: 48     Fields:    Translation:Humans
  28. Bove-Fenderson E, Duffy K, Mannstadt M. Broadening Our Horizons: JBMR and JBMR Plus Embrace Preprints. JBMR Plus. 2018 Mar; 2(2):59-61. PMID: 30283891; PMCID: PMC6124178.
    Citations: 3     
  29. Bove-Fenderson E, Duffy K, Mannstadt M. Sharing the Wealth: ASBMR Journals Update Policies on Data Sharing and Data Repositories. J Bone Miner Res. 2018 03; 33(3):369-370. PMID: 29465810.
    Citations:    Fields:    
  30. Bove-Fenderson E, Duffy K, Mannstadt M. Broadening Our Horizons: JBMR and JBMR Plus Embrace Preprints. J Bone Miner Res. 2018 02; 33(2):185-187. PMID: 29405377.
    Citations: 1     Fields:    
  31. Vokes TJ, Mannstadt M, Levine MA, Clarke BL, Lakatos P, Chen K, Piccolo R, Krasner A, Shoback DM, Bilezikian JP. Recombinant Human Parathyroid Hormone Effect on Health-Related Quality of Life in Adults With Chronic Hypoparathyroidism. J Clin Endocrinol Metab. 2018 02 01; 103(2):722-731. PMID: 29099947; PMCID: PMC6458961.
    Citations: 21     Fields:    Translation:Humans
  32. Mannstadt M, Bilezikian JP, Thakker RV, Hannan FM, Clarke BL, Rejnmark L, Mitchell DM, Vokes TJ, Winer KK, Shoback DM. Hypoparathyroidism. Nat Rev Dis Primers. 2017 Oct 05; 3:17080. PMID: 28980621.
    Citations: 8     Fields:    
  33. Bilezikian JP, Clarke BL, Mannstadt M, Rothman J, Vokes T, Lee HM, Krasner A. Safety and Efficacy of Recombinant Human Parathyroid Hormone in Adults With Hypoparathyroidism Randomly Assigned to Receive Fixed 25-µg or 50-µg Daily Doses. Clin Ther. 2017 Oct; 39(10):2096-2102. PMID: 28942334.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  34. Stephen AE, Mannstadt M, Hodin RA. Indications for Surgical Management of Hyperparathyroidism: A Review. JAMA Surg. 2017 Sep 01; 152(9):878-882. PMID: 28658490.
    Citations: 9     Fields:    Translation:Humans
  35. Mannstadt M, Bilezikian JP, Thakker RV, Hannan FM, Clarke BL, Rejnmark L, Mitchell DM, Vokes TJ, Winer KK, Shoback DM. Hypoparathyroidism. Nat Rev Dis Primers. 2017 08 31; 3:17055. PMID: 28857066.
    Citations: 38     Fields:    Translation:Humans
  36. Bi R, Fan Y, Luo E, Yuan Q, Mannstadt M. Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation. J Vis Exp. 2017 03 14; (121). PMID: 28362393.
    Citations:    Fields:    Translation:Animals
  37. Roszko KL, Bi R, Gorvin CM, Bräuner-Osborne H, Xiong XF, Inoue A, Thakker RV, Strømgaard K, Gardella T, Mannstadt M. Knockin mouse with mutant Ga11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors. JCI Insight. 2017 02 09; 2(3):e91079. PMID: 28194446; PMCID: PMC5291736.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  38. Fan Y, Hanai JI, Le PT, Bi R, Maridas D, DeMambro V, Figueroa CA, Kir S, Zhou X, Mannstadt M, Baron R, Bronson RT, Horowitz MC, Wu JY, Bilezikian JP, Dempster DW, Rosen CJ, Lanske B. Parathyroid Hormone Directs Bone Marrow Mesenchymal Cell Fate. Cell Metab. 2017 03 07; 25(3):661-672. PMID: 28162969; PMCID: PMC5342925.
    Citations: 141     Fields:    Translation:HumansAnimalsCells
  39. Roszko KL, Bi RD, Mannstadt M. Autosomal Dominant Hypocalcemia (Hypoparathyroidism) Types 1 and 2. Front Physiol. 2016; 7:458. PMID: 27803672; PMCID: PMC5067375.
    Citations: 23     
  40. Clarke BL, Vokes TJ, Bilezikian JP, Shoback DM, Lagast H, Mannstadt M. Effects of parathyroid hormone rhPTH(1-84) on phosphate homeostasis and vitamin D metabolism in hypoparathyroidism: REPLACE phase 3 study. Endocrine. 2017 Jan; 55(1):273-282. PMID: 27734257.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  41. Xiong XF, Zhang H, Underwood CR, Harpsøe K, Gardella TJ, Wöldike MF, Mannstadt M, Gloriam DE, Bräuner-Osborne H, Strømgaard K. Total synthesis and structure-activity relationship studies of a series of selective G protein inhibitors. Nat Chem. 2016 11; 8(11):1035-1041. PMID: 27768111.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  42. Clarke BL, Brown EM, Collins MT, Jüppner H, Lakatos P, Levine MA, Mannstadt MM, Bilezikian JP, Romanischen AF, Thakker RV. Epidemiology and Diagnosis of Hypoparathyroidism. J Clin Endocrinol Metab. 2016 Jun; 101(6):2284-99. PMID: 26943720; PMCID: PMC5393595.
    Citations: 57     Fields:    Translation:Humans
  43. Bilezikian JP, Brandi ML, Cusano NE, Mannstadt M, Rejnmark L, Rizzoli R, Rubin MR, Winer KK, Liberman UA, Potts JT. Management of Hypoparathyroidism: Present and Future. J Clin Endocrinol Metab. 2016 Jun; 101(6):2313-24. PMID: 26938200; PMCID: PMC5393596.
    Citations: 46     Fields:    Translation:Humans
  44. Bi R, Fan Y, Lauter K, Hu J, Watanabe T, Cradock J, Yuan Q, Gardella T, Mannstadt M. Diphtheria Toxin- and GFP-Based Mouse Models of Acquired Hypoparathyroidism and Treatment With a Long-Acting Parathyroid Hormone Analog. J Bone Miner Res. 2016 05; 31(5):975-84. PMID: 26678919; PMCID: PMC4862881.
    Citations: 12     Fields:    Translation:Animals
  45. Lee S, Mannstadt M, Guo J, Kim SM, Yi HS, Khatri A, Dean T, Okazaki M, Gardella TJ, Jüppner H. A Homozygous [Cys25]PTH(1-84) Mutation That Impairs PTH/PTHrP Receptor Activation Defines a Novel Form of Hypoparathyroidism. J Bone Miner Res. 2015 Oct; 30(10):1803-13. PMID: 25891861; PMCID: PMC4580526.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  46. Monis EL, Mannstadt M. Hypoparathyroidism - disease update and emerging treatments. Ann Endocrinol (Paris). 2015 May; 76(2):84-8. PMID: 25882889.
    Citations: 2     Fields:    Translation:Humans
  47. Eyal O, Oren A, Jüppner H, Somech R, De Bellis A, Mannstadt M, Szalat A, Bleiberg M, Weisman Y, Weintrob N. Hypoparathyroidism and central diabetes insipidus: in search of the link. Eur J Pediatr. 2014 Dec; 173(12):1731-4. PMID: 25367057; PMCID: PMC5103624.
    Citations: 2     Fields:    Translation:Humans
  48. Mannstadt M, Lin AE, Le LP. Case records of the Massachusetts General Hospital. Case 24-2014. A 27-year-old man with severe osteoporosis and multiple bone fractures. N Engl J Med. 2014 Jul 31; 371(5):465-72. PMID: 25075839.
    Citations: 2     Fields:    Translation:Humans
  49. Mannstadt M, Clarke BL, Vokes T, Brandi ML, Ranganath L, Fraser WD, Lakatos P, Bajnok L, Garceau R, Mosekilde L, Lagast H, Shoback D, Bilezikian JP. Efficacy and safety of recombinant human parathyroid hormone (1-84) in hypoparathyroidism (REPLACE): a double-blind, placebo-controlled, randomised, phase 3 study. Lancet Diabetes Endocrinol. 2013 Dec; 1(4):275-83. PMID: 24622413.
    Citations: 72     Fields:    Translation:HumansCTClinical Trials
  50. Mannstadt M, Harris M, Bravenboer B, Chitturi S, Dreijerink KM, Lambright DG, Lim ET, Daly MJ, Gabriel S, Jüppner H. Germline mutations affecting Ga11 in hypoparathyroidism. N Engl J Med. 2013 Jun 27; 368(26):2532-4. PMID: 23802536; PMCID: PMC3750735.
    Citations: 32     Fields:    Translation:Humans
  51. Zhao W, Petit E, Gafni RI, Collins MT, Robey PG, Seton M, Miller KK, Mannstadt M. Mutations in NOTCH2 in patients with Hajdu-Cheney syndrome. Osteoporos Int. 2013 Aug; 24(8):2275-81. PMID: 23389697.
    Citations: 23     Fields:    Translation:Humans
  52. Mitchell DM, Regan S, Cooley MR, Lauter KB, Vrla MC, Becker CB, Burnett-Bowie SA, Mannstadt M. Long-term follow-up of patients with hypoparathyroidism. J Clin Endocrinol Metab. 2012 Dec; 97(12):4507-14. PMID: 23043192; PMCID: PMC3513540.
    Citations: 98     Fields:    Translation:Humans
  53. Mannstadt M, Magen D, Segawa H, Stanley T, Sharma A, Sharma A, Sasaki S, Bergwitz C, Mounien L, Boepple P, Thorens B, Zelikovic I, Jüppner H. Fanconi-Bickel syndrome and autosomal recessive proximal tubulopathy with hypercalciuria (ARPTH) are allelic variants caused by GLUT2 mutations. J Clin Endocrinol Metab. 2012 Oct; 97(10):E1978-86. PMID: 22865906; PMCID: PMC3462928.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  54. Block GA, Wheeler DC, Persky MS, Kestenbaum B, Ketteler M, Spiegel DM, Allison MA, Asplin J, Smits G, Hoofnagle AN, Kooienga L, Thadhani R, Mannstadt M, Wolf M, Chertow GM. Effects of phosphate binders in moderate CKD. J Am Soc Nephrol. 2012 Aug; 23(8):1407-15. PMID: 22822075; PMCID: PMC3402292.
    Citations: 211     Fields:    Translation:Humans
  55. Yi HS, Eom YS, Park IeB, Lee S, Hong S, Jüppner H, Mannstadt M, Lee S. Identification and characterization of C106R, a novel mutation in the DNA-binding domain of GCMB, in a family with autosomal-dominant hypoparathyroidism. Clin Endocrinol (Oxf). 2012 May; 76(5):625-33. PMID: 22066718.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  56. Mannstadt M, Holick E, Zhao W, Jüppner H. Mutational analysis of GCMB, a parathyroid-specific transcription factor, in parathyroid adenoma of primary hyperparathyroidism. J Endocrinol. 2011 Aug; 210(2):165-71. PMID: 21642377.
    Citations: 8     Fields:    Translation:Humans
  57. Gutiérrez OM, Mannstadt M, Isakova T, Rauh-Hain JA, Tamez H, Shah A, Smith K, Lee H, Thadhani R, Jüppner H, Wolf M. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med. 2008 Aug 07; 359(6):584-92. PMID: 18687639; PMCID: PMC2890264.
    Citations: 690     Fields:    Translation:Humans
  58. Mannstadt M, Lorente C, and Jüppner H. Rapid Detection of Intact FGF-23 in Tumor Tissue From Patients With Oncogenic Osteomalacia. . Clin Chemistry. 2008; 54:1251-53.
  59. Mannstadt M, Lorente C, Jüppner H. Rapid detection of intact FGF-23 in tumor tissue from patients with oncogenic osteomalacia. Clin Chem. 2008 Jul; 54(7):1252-4. PMID: 18593970.
    Citations: 2     Fields:    Translation:Humans
  60. Mannstadt M, Bertrand G, Muresan M, Weryha G, Leheup B, Pulusani SR, Grandchamp B, Jüppner H, Silve C. Dominant-negative GCMB mutations cause an autosomal dominant form of hypoparathyroidism. J Clin Endocrinol Metab. 2008 Sep; 93(9):3568-76. PMID: 18583467; PMCID: PMC2567849.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  61. Bazari H, Jaff MR, Mannstadt M, Yan S. Case records of the Massachusetts General Hospital. Case 7-2007. A 59-year-old woman with diabetic renal disease and nonhealing skin ulcers. N Engl J Med. 2007 Mar 08; 356(10):1049-57. PMID: 17347459.
    Citations: 5     Fields:    Translation:Humans
  62. Sabatine M, editor. Pocket Medicine. 2007.
  63. Schindler S, Mannstadt M, Urena P, Segre GV, Stein G. PTH secretion in patients with chronic renal failure assessed by a modified CiCa clamp method: effects of 1-year calcitriol therapy. Clin Nephrol. 2004 Apr; 61(4):253-60. PMID: 15125031.
    Citations: 2     Fields:    Translation:Humans
  64. Jonsson KB, Mannstadt M, Miyauchi A, Yang IM, Stein G, Jüppner H. Extracts from tumors causing oncogenic osteomalacia inhibit phosphate uptake in opossum kidney cells. J Endocrinol. 2001 Jun; 169(3):613-20. PMID: 11375132.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  65. White KE, Jonsson KB, Carn G, Hampson G, Spector TD, Mannstadt M, Lorenz-Depiereux B, Miyauchi A, Yang IM, Ljunggren O, Meitinger T, Strom TM, Jüppner H, Econs MJ. The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting. J Clin Endocrinol Metab. 2001 Feb; 86(2):497-500. PMID: 11157998.
    Citations: 73     Fields:    Translation:HumansAnimalsCells
  66. Mannstadt M, Sing A, Leitritz L, Brenner-Maucher K, Bogner J. Conservative management of biliary obstruction due to Fasciola hepatica. Clin Infect Dis. 2000 Nov; 31(5):1301-3. PMID: 11073771.
    Citations: 2     Fields:    Translation:HumansAnimals
  67. Brenner-Maucher K, Szeimies U, Mannstadt M, Gross M. [Fasciola hepatica: the sonographic and computed tomographic changes in a case with a liver fluke]. Rofo. 2000 Jun; 172(6):562-3. PMID: 10916555.
    Citations:    Fields:    Translation:HumansAnimals
  68. Mannstadt M, Jüppner H, Gardella TJ. Receptors for PTH and PTHrP: their biological importance and functional properties. Am J Physiol. 1999 11; 277(5):F665-75. PMID: 10564229.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  69. Jüppner H, Schipani E, Bastepe M, Cole DE, Lawson ML, Mannstadt M, Hendy GN, Plotkin H, Koshiyama H, Koh T, Crawford JD, Olsen BR, Vikkula M. The gene responsible for pseudohypoparathyroidism type Ib is paternally imprinted and maps in four unrelated kindreds to chromosome 20q13.3. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11798-803. PMID: 9751745; PMCID: PMC21720.
    Citations: 43     Fields:    Translation:HumansCells
  70. Mannstadt M, Luck MD, Gardella TJ, Jüppner H. Evidence for a ligand interaction site at the amino-terminus of the parathyroid hormone (PTH)/PTH-related protein receptor from cross-linking and mutational studies. J Biol Chem. 1998 Jul 03; 273(27):16890-6. PMID: 9642250.
    Citations: 11     Fields:    Translation:AnimalsCells
  71. Mannstadt M. [The knockout mouse--a revolutionizing model in biomedical research]. Med Klin (Munich). 1997 Sep 15; 92(9):558-60. PMID: 9411205.
    Citations: 1     Fields:    Translation:HumansAnimals
  72. Mannstadt M, Drüeke TB. [Parathyroid hormone receptors: from cloning to physiological, physiopathological and clinical implications]. Nephrologie. 1997; 18(1):5-10. PMID: 9121603.
    Citations:    Fields:    Translation:HumansAnimals
  73. Hruby M, Ureña P, Mannstadt M, Schmitt F, Lacour B, Drüeke TB. Effects of new vitamin D analogues on parathyroid function in chronically uraemic rats with secondary hyperparathyroidism. Nephrol Dial Transplant. 1996 Sep; 11(9):1781-6. PMID: 8918622.
    Citations:    Fields:    Translation:Animals
  74. Ureña P, Mannstadt M, Hruby M, Ferreira A, Schmitt F, Silve C, Ardaillou R, Lacour B, Abou-Samra AB, Segre GV, et al. Parathyroidectomy does not prevent the renal PTH/PTHrP receptor down-regulation in uremic rats. Kidney Int. 1995 Jun; 47(6):1797-805. PMID: 7643551.
    Citations: 10     Fields:    Translation:AnimalsCells
  75. Mannstadt M, Touam M, Fink E, Ureña P, Hruby M, Zingraff J, Uhlenbusch-Körwer I, Grassmann A, Lemke HD, Drüeke TB. No generation of bradykinin with a new polyacrylonitrile membrane (SPAN) in haemodialysis patients treated with ACE inhibitors. Nephrol Dial Transplant. 1995; 10(9):1696-700. PMID: 8559491.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  76. Ureña P, Kubrusly M, Mannstadt M, Hruby M, Trinh MM, Silve C, Lacour B, Abou-Samra AB, Segre GV, Drüeke T. The renal PTH/PTHrP receptor is down-regulated in rats with chronic renal failure. Kidney Int. 1994 Feb; 45(2):605-11. PMID: 8164450.
    Citations: 13     Fields:    Translation:AnimalsCells
  77. Ureña P, Kubrusly M, Mannstadt M, Sarfati E, Drüeke T. Total or subtotal parathyroidectomy in uremic patients? Clin Nephrol. 1994 Jan; 41(1):59-60. PMID: 8137572.
    Citations: 2     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.