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Jeffrey Stuart Brown, Ph.D.

Title
Institution
Department
Address
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Biography
1995 - 1998
Doctoral Training Fellowship
1999 - 2000
Doctoral Dissertation Grant
2006
Exceptional Reviewer (2004-2005)
2008
Best paper published in Pharmacoepidemiology and Drug Safety (PDS) in 2007
2008
Exceptional Reviewer (2006-2007)
2010
Exceptional Reviewer (2009)

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. RC1LM010371 (BROWN, JEFFREY STUART) Sep 30, 2009 - Sep 29, 2012
    NIH/NLM
    Data Mining Electronic Health Records for Drug Adverse Events
    Role: Principal Investigator
  2. R03HS010016 (BROWN, JEFFREY STUART) Sep 30, 1998 - Sep 29, 2000
    AHRQ
    CLOZAPINE'S IMPACT ON SCHIZOPHRENIC MEDICAID ENROLLEES
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Brown JS, Maro JC, Nguyen M, Ball R. Using and improving distributed data networks to generate actionable evidence: the case of real-world outcomes in the Food and Drug Administration's Sentinel system. J Am Med Inform Assoc. 2020 May 01; 27(5):793-797. PMID: 32279080.
    Citations:    
  2. McMahon AW, Cooper WO, Brown JS, Carleton B, Doshi-Velez F, Kohane I, Goldman JL, Hoffman MA, Kamaleswaran R, Sakiyama M, Sekine S, Sturkenboom MCJM, Turner MA, Califf RM. Big Data in the Assessment of Pediatric Medication Safety. Pediatrics. 2020 02; 145(2). PMID: 31937606.
    Citations:    
  3. Marsolo KA, Brown JS, Hernandez AF, Hammill BG, Raman SR, Syat B, Platt R, Curtis LH. Considerations for using distributed research networks to conduct aspects of randomized trials. Contemp Clin Trials Commun. 2020 Mar; 17:100515. PMID: 31956724.
    Citations:    
  4. Panozzo CA, Curtis LH, Marshall J, Fine L, Wells BL, Brown JS, Haynes K, Pawloski PA, Hernandez AF, Malek S, Syat B, Platt R. Incidence of statin use in older adults with and without cardiovascular disease and diabetes mellitus, January 2008- March 2018. PLoS One. 2019; 14(12):e0223515. PMID: 31805056.
    Citations:    
  5. Wang SV, Patterson OV, Gagne JJ, Brown JS, Ball R, Jonsson P, Wright A, Zhou L, Goettsch W, Bate A. Transparent Reporting on Research Using Unstructured Electronic Health Record Data to Generate 'Real World' Evidence of Comparative Effectiveness and Safety. Drug Saf. 2019 11; 42(11):1297-1309. PMID: 31452075.
    Citations:    
  6. Straub L, Gagne JJ, Maro JC, Nguyen MD, Beaulieu N, Brown JS, Kennedy A, Johnson M, Wright A, Zhou L, Wang SV. Evaluation of Use of Technologies to Facilitate Medical Chart Review. Drug Saf. 2019 09; 42(9):1071-1080. PMID: 31111340.
    Citations:    
  7. Lockhart CM, McDermott CL, Felix T, Lin ND, Cziraky MJ, Mendelsohn AB, Brown JS. Barriers and facilitators to conduct high-quality, large-scale safety and comparative effectiveness research: The Biologics and Biosimilars Collective Intelligence Consortium experience. Pharmacoepidemiol Drug Saf. 2019 Aug 11. PMID: 31402533.
    Citations:    
  8. Rogers JR, Callahan TJ, Kang T, Bauck A, Khare R, Brown JS, Kahn MG, Weng C. A Data Element-Function Conceptual Model for Data Quality Checks. EGEMS (Wash DC). 2019 Apr 23; 7(1):17. PMID: 31065558.
    Citations:    
  9. Raman SR, Brown JS, Curtis LH, Haynes K, Marshall J, Pawloski PA, Platt R. Cancer Screening Results and Follow-up Using Routinely Collected Electronic Health Data: Estimates for Breast, Colon, and Cervical Cancer Screenings. J Gen Intern Med. 2019 03; 34(3):341-343. PMID: 30350029.
    Citations:    Fields:    
  10. Malenfant JM, Hochstadt J, Nolan B, Barrett K, Corriveau D, Dee D, Harris M, Herzig-Marx C, Nair VP, Wyner Z, Brown JS. Cross-Network Directory Service: Infrastructure to enable collaborations across distributed research networks. Learn Health Syst. 2019 Apr; 3(2):e10187. PMID: 31245605.
    Citations:    
  11. Platt RW, Platt R, Brown JS, Henry DA, Klungel OH, Suissa S. How pharmacoepidemiology networks can manage distributed analyses to improve replicability and transparency and minimize bias. Pharmacoepidemiol Drug Saf. 2019 Jan 15. PMID: 30648307.
    Citations:    Fields:    
  12. Platt R, Brown JS, Robb M, McClellan M, Ball R, Nguyen MD, Sherman RE. The FDA Sentinel Initiative - An Evolving National Resource. N Engl J Med. 2018 Nov 29; 379(22):2091-2093. PMID: 30485777.
    Citations:    Fields:    Translation:Humans
  13. Sobel RE, Bate A, Marshall J, Haynes K, Selvam N, Nair V, Daniel G, Brown JS, Reynolds RF. Do FDA label changes work? Assessment of the 2010 class label change for proton pump inhibitors using the Sentinel System's analytic tools. Pharmacoepidemiol Drug Saf. 2018 03; 27(3):332-339. PMID: 29392851.
    Citations: 2     Fields:    
  14. Huser V, Kahn MG, Brown JS, Gouripeddi R. Methods for examining data quality in healthcare integrated data repositories. Pac Symp Biocomput. 2018; 23:628-633. PMID: 29218922.
    Citations:    Fields:    Translation:HumansPHPublic Health
  15. Johannes CB, McQuay LJ, Midkiff KD, Calingaert B, Andrews EB, Tennis P, Brown JS, Camargo CA, DiSantostefano RL, Rothman KJ, Stürmer T, Lanes S, Davis KJ. The feasibility of using multiple databases to study rare outcomes: the potential effect of long-acting beta agonists with inhaled corticosteroid therapy on asthma mortality. Pharmacoepidemiol Drug Saf. 2017 Apr; 26(4):446-458. PMID: 28000298.
    Citations:    Fields:    Translation:Humans
  16. Garabedian LF, Ross-Degnan D, Soumerai SB, Choudhry NK, Brown JS. Impact of Massachusetts Health Reform on Enrollment Length and Health Care Utilization in the Unsubsidized Individual Market. Health Serv Res. 2017 06; 52(3):1118-1137. PMID: 27456334.
    Citations:    Fields:    Translation:Humans
  17. Bourke A, Bate A, Sauer BC, Brown JS, Hall GC. Evidence generation from healthcare databases: recommendations for managing change. Pharmacoepidemiol Drug Saf. 2016 07; 25(7):749-54. PMID: 27183900.
    Citations: 1     Fields:    Translation:Humans
  18. Lanes S, Brown JS, Haynes K, Pollack MF, Walker AM. Identifying health outcomes in healthcare databases. Pharmacoepidemiol Drug Saf. 2015 Oct; 24(10):1009-16. PMID: 26282185.
    Citations: 4     Fields:    Translation:Humans
  19. Kahn MG, Brown JS, Chun AT, Davidson BN, Meeker D, Ryan PB, Schilling LM, Weiskopf NG, Williams AE, Zozus MN. Transparent reporting of data quality in distributed data networks. EGEMS (Wash DC). 2015; 3(1):1052. PMID: 25992385.
    Citations: 17     
  20. Vogel J, Brown JS, Land T, Platt R, Klompas M. MDPHnet: secure, distributed sharing of electronic health record data for public health surveillance, evaluation, and planning. Am J Public Health. 2014 Dec; 104(12):2265-70. PMID: 25322301.
    Citations: 13     Fields:    Translation:HumansPHPublic Health
  21. Maro JC, Brown JS, Dal Pan GJ, Li L. Orphan therapies: making best use of postmarket data. J Gen Intern Med. 2014 Aug; 29 Suppl 3:S745-51. PMID: 25029972.
    Citations: 2     Fields:    Translation:Humans
  22. Fleurence RL, Curtis LH, Califf RM, Platt R, Selby JV, Brown JS. Launching PCORnet, a national patient-centered clinical research network. J Am Med Inform Assoc. 2014 Jul-Aug; 21(4):578-82. PMID: 24821743.
    Citations: 75     Fields:    Translation:Humans
  23. Maro JC, Brown JS, Dal Pan GJ, Kulldorff M. Minimizing signal detection time in postmarket sequential analysis: balancing positive predictive value and sensitivity. Pharmacoepidemiol Drug Saf. 2014 Aug; 23(8):839-48. PMID: 24700557.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  24. Holmes JH, Elliott TE, Brown JS, Raebel MA, Davidson A, Nelson AF, Chung A, La Chance P, Steiner JF. Clinical research data warehouse governance for distributed research networks in the USA: a systematic review of the literature. J Am Med Inform Assoc. 2014 Jul-Aug; 21(4):730-6. PMID: 24682495.
    Citations: 9     Fields:    
  25. Raebel MA, Haynes K, Woodworth TS, Saylor G, Cavagnaro E, Coughlin KO, Curtis LH, Weiner MG, Archdeacon P, Brown JS. Electronic clinical laboratory test results data tables: lessons from Mini-Sentinel. Pharmacoepidemiol Drug Saf. 2014 Jun; 23(6):609-18. PMID: 24677577.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  26. Kim SC, Gillet VG, Feldman S, Lii H, Toh S, Brown JS, Katz JN, Solomon DH, Schneeweiss S. Validation of claims-based algorithms for identification of high-grade cervical dysplasia and cervical cancer. Pharmacoepidemiol Drug Saf. 2013 Nov; 22(11):1239-44. PMID: 24027140.
    Citations: 4     Fields:    Translation:Humans
  27. Maro JC, Brown JS, Kulldorff M. Medical product safety surveillance: how many databases to use? Epidemiology. 2013 Sep; 24(5):692-9. PMID: 23867812.
    Citations: 3     Fields:    Translation:Humans
  28. Toh S, Gagne JJ, Rassen JA, Fireman BH, Kulldorff M, Brown JS. Confounding adjustment in comparative effectiveness research conducted within distributed research networks. Med Care. 2013 Aug; 51(8 Suppl 3):S4-10. PMID: 23752258.
    Citations: 20     Fields:    Translation:Humans
  29. Brown JS, Kahn M, Toh S. Data quality assessment for comparative effectiveness research in distributed data networks. Med Care. 2013 Aug; 51(8 Suppl 3):S22-9. PMID: 23793049.
    Citations: 26     Fields:    Translation:Humans
  30. Toh S, Baker MA, Brown JS, Kornegay C, Platt R. Rapid assessment of cardiovascular risk among users of smoking cessation drugs within the US Food and Drug Administration's Mini-Sentinel program. JAMA Intern Med. 2013 May 13; 173(9):817-9. PMID: 23529063.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  31. Kulldorff M, Dashevsky I, Avery TR, Chan AK, Davis RL, Graham D, Platt R, Andrade SE, Boudreau D, Gunter MJ, Herrinton LJ, Pawloski PA, Raebel MA, Roblin D, Brown JS. Drug safety data mining with a tree-based scan statistic. Pharmacoepidemiol Drug Saf. 2013 May; 22(5):517-23. PMID: 23512870.
    Citations: 10     Fields:    Translation:Humans
  32. Brown JS, Petronis KR, Bate A, Zhang F, Dashevsky I, Kulldorff M, Avery TR, Davis RL, Chan KA, Andrade SE, Boudreau D, Gunter MJ, Herrinton L, Pawloski PA, Raebel MA, Roblin D, Smith D, Reynolds R. Drug Adverse Event Detection in Health Plan Data Using the Gamma Poisson Shrinker and Comparison to the Tree-based Scan Statistic. Pharmaceutics. 2013 Mar 14; 5(1):179-200. PMID: 24300404.
    Citations: 4     
  33. Avery TR, Kulldorff M, Vilk Y, Li L, Cheetham TC, Dublin S, Davis RL, Liu L, Herrinton L, Brown JS. Near real-time adverse drug reaction surveillance within population-based health networks: methodology considerations for data accrual. Pharmacoepidemiol Drug Saf. 2013 May; 22(5):488-95. PMID: 23401239.
    Citations: 3     Fields:    Translation:Humans
  34. Velentgas P, Amato AA, Bohn RL, Chan KA, Cochrane T, Funch DP, Dashevsky I, Duddy AL, Gladowski P, Greenberg SA, Kramer JM, McMahill-Walraven C, Nakasato C, Spettell CM, Syat BL, Wahl PM, Walker AM, Zhang F, Brown JS, Platt R. Risk of Guillain-Barré syndrome after meningococcal conjugate vaccination. Pharmacoepidemiol Drug Saf. 2012 Dec; 21(12):1350-8. PMID: 22807266.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  35. Curtis LH, Weiner MG, Boudreau DM, Cooper WO, Daniel GW, Nair VP, Raebel MA, Beaulieu NU, Rosofsky R, Woodworth TS, Brown JS. Design considerations, architecture, and use of the Mini-Sentinel distributed data system. Pharmacoepidemiol Drug Saf. 2012 Jan; 21 Suppl 1:23-31. PMID: 22262590.
    Citations: 57     Fields:    Translation:Humans
  36. Platt R, Carnahan RM, Brown JS, Chrischilles E, Curtis LH, Hennessy S, Nelson JC, Racoosin JA, Robb M, Schneeweiss S, Toh S, Weiner MG. The U.S. Food and Drug Administration's Mini-Sentinel program: status and direction. Pharmacoepidemiol Drug Saf. 2012 Jan; 21 Suppl 1:1-8. PMID: 22262586.
    Citations: 70     Fields:    Translation:Humans
  37. Hall GC, Sauer B, Bourke A, Brown JS, Reynolds MW, LoCasale R, Casale RL. Guidelines for good database selection and use in pharmacoepidemiology research. Pharmacoepidemiol Drug Saf. 2012 Jan; 21(1):1-10. PMID: 22069180.
    Citations: 17     Fields:    Translation:Humans
  38. Maro JC, Brown JS. Impact of exposure accrual on sequential postmarket evaluations: a simulation study. Pharmacoepidemiol Drug Saf. 2011 Nov; 20(11):1184-91. PMID: 22020903.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  39. Behrman RE, Benner JS, Brown JS, McClellan M, Woodcock J, Platt R. Developing the Sentinel System--a national resource for evidence development. N Engl J Med. 2011 Feb 10; 364(6):498-9. PMID: 21226658.
    Citations: 71     Fields:    Translation:Humans
  40. Mapel D, Schum M, Yood M, Brown J, Miller D, Davis K. Pneumonia among COPD patients using inhaled corticosteroids and long-acting bronchodilators. Prim Care Respir J. 2010 Jun; 19(2):109-17. PMID: 20082059.
    Citations: 5     Fields:    Translation:Humans
  41. Brown JS, Holmes JH, Shah K, Hall K, Lazarus R, Platt R. Distributed health data networks: a practical and preferred approach to multi-institutional evaluations of comparative effectiveness, safety, and quality of care. Med Care. 2010 Jun; 48(6 Suppl):S45-51. PMID: 20473204.
    Citations: 58     Fields:    Translation:Humans
  42. Brown JS, Moore KM, Braun MM, Ziyadeh N, Chan KA, Lee GM, Kulldorff M, Walker AM, Platt R. Active influenza vaccine safety surveillance: potential within a healthcare claims environment. Med Care. 2009 Dec; 47(12):1251-7. PMID: 19786905.
    Citations: 6     Fields:    Translation:Humans
  43. Moore KM, Duddy A, Lee GM, Velentgas P, Burwen DR, Platt R, Brown JS. Outpatient urticaria diagnosis codes have limited predictive value for same-day influenza vaccine adverse event detection. J Clin Epidemiol. 2010 Apr; 63(4):407-11. PMID: 19889513.
    Citations: 2     Fields:    Translation:Humans
  44. Maro JC, Platt R, Holmes JH, Strom BL, Hennessy S, Lazarus R, Brown JS. Design of a national distributed health data network. Ann Intern Med. 2009 Sep 01; 151(5):341-4. PMID: 19638403.
    Citations: 46     Fields:    Translation:Humans
  45. Brown JS, Kulldorff M, Petronis KR, Reynolds R, Chan KA, Davis RL, Graham D, Andrade SE, Raebel MA, Herrinton L, Roblin D, Boudreau D, Smith D, Gurwitz JH, Gunter MJ, Platt R. Early adverse drug event signal detection within population-based health networks using sequential methods: key methodologic considerations. Pharmacoepidemiol Drug Saf. 2009 Mar; 18(3):226-34. PMID: 19148879.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  46. Velentgas P, Bohn RL, Brown JS, Chan KA, Gladowski P, Holick CN, Kramer JM, Nakasato C, Spettell CM, Walker AM, Zhang F, Platt R. A distributed research network model for post-marketing safety studies: the Meningococcal Vaccine Study. Pharmacoepidemiol Drug Saf. 2008 Dec; 17(12):1226-34. PMID: 18956428.
    Citations: 11     Fields:    Translation:Humans
  47. Moore KM, Duddy A, Braun MM, Platt R, Brown JS. Potential population-based electronic data sources for rapid pandemic influenza vaccine adverse event detection: a survey of health plans. Pharmacoepidemiol Drug Saf. 2008 Dec; 17(12):1137-41. PMID: 18763248.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  48. Brown JS, Neumann PJ, Papadopoulos G, Ruoff G, Diamond M, Menzin J. Migraine frequency and health utilities: findings from a multisite survey. Value Health. 2008 Mar-Apr; 11(2):315-21. PMID: 18380644.
    Citations: 6     Fields:    Translation:Humans
  49. Andrade SE, Raebel MA, Brown J, Lane K, Livingston J, Boudreau D, Rolnick SJ, Roblin D, Smith DH, Dal Pan GJ, Scott PE, Platt R. Outpatient use of cardiovascular drugs during pregnancy. Pharmacoepidemiol Drug Saf. 2008 Mar; 17(3):240-7. PMID: 18200619.
    Citations: 16     Fields:    Translation:Humans
  50. Brown JS, Kulldorff M, Chan KA, Davis RL, Graham D, Pettus PT, Andrade SE, Raebel MA, Herrinton L, Roblin D, Boudreau D, Smith D, Gurwitz JH, Gunter MJ, Platt R. Early detection of adverse drug events within population-based health networks: application of sequential testing methods. Pharmacoepidemiol Drug Saf. 2007 Dec; 16(12):1275-84. PMID: 17955500.
    Citations: 28     Fields:    Translation:HumansPHPublic Health
  51. Andrade SE, Raebel MA, Brown J, Lane K, Livingston J, Boudreau D, Rolnick SJ, Roblin D, Smith DH, Willy ME, Staffa JA, Platt R. Use of antidepressant medications during pregnancy: a multisite study. Am J Obstet Gynecol. 2008 Feb; 198(2):194.e1-5. PMID: 17905176.
    Citations: 95     Fields:    Translation:Humans
  52. Lieu TA, Kulldorff M, Davis RL, Lewis EM, Weintraub E, Yih K, Yin R, Brown JS, Platt R. Real-time vaccine safety surveillance for the early detection of adverse events. Med Care. 2007 Oct; 45(10 Supl 2):S89-95. PMID: 17909389.
    Citations: 27     Fields:    Translation:Humans
  53. Kazan-Tannus JF, Dialani V, Kataoka ML, Chiang G, Feldman HA, Brown JS, Levine D. MR volumetry of brain and CSF in fetuses referred for ventriculomegaly. AJR Am J Roentgenol. 2007 Jul; 189(1):145-51. PMID: 17579164.
    Citations: 14     Fields:    Translation:Humans
  54. Brown JS, Rupnow MF, Neumann P, Friedman M, Menzin J. Cost effectiveness of topiramate in the prevention of migraines in the United States: an update. Manag Care Interface. 2006 Dec; 19(12):31-8. PMID: 17274479.
    Citations: 2     Fields:    Translation:Humans
  55. Brown JS, Papadopoulos G, Neumann PJ, Price M, Friedman M, Menzin J. Cost-effectiveness of migraine prevention: the case of topiramate in the UK. Cephalalgia. 2006 Dec; 26(12):1473-82. PMID: 17116098.
    Citations: 3     Fields:    Translation:Humans
  56. Brown JS, Papadopoulos G, Neumann PJ, Friedman M, Miller JD, Menzin J. Cost-effectiveness of topiramate in migraine prevention: results from a pharmacoeconomic model of topiramate treatment. Headache. 2005 Sep; 45(8):1012-22. PMID: 16109115.
    Citations: 9     Fields:    Translation:Humans
  57. Simoni-Wastila L, Ross-Degnan D, Mah C, Gao X, Brown J, Cosler LE, Fanning T, Gallagher P, Salzman C, Soumerai SB. A retrospective data analysis of the impact of the New York triplicate prescription program on benzodiazepine use in medicaid patients with chronic psychiatric and neurologic disorders. Clin Ther. 2004 Feb; 26(2):322-36. PMID: 15038954.
    Citations: 14     Fields:    Translation:Humans
  58. Ross-Degnan D, Simoni-Wastila L, Brown JS, Gao X, Mah C, Cosler LE, Fanning T, Gallagher P, Salzman C, Shader RI, Inui TS, Soumerai SB. A controlled study of the effects of state surveillance on indicators of problematic and non-problematic benzodiazepine use in a Medicaid population. Int J Psychiatry Med. 2004; 34(2):103-23. PMID: 15387395.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  59. Pegus C, Bazzarre TL, Brown JS, Menzin J. Effect of the Heart At Work program on awareness of risk factors, self-efficacy, and health behaviors. J Occup Environ Med. 2002 Mar; 44(3):228-36. PMID: 11911024.
    Citations: 7     Fields:    Translation:Humans
  60. Brown JS, Kaitin KI, McAuslane N, Thomas K, Walker SR. Population exposure required to assess clinical safety: a report to the International Conference on Harmonization Efficacy Working Group. Drug Information Journal. 1996; 10(30):17-27.
  61. DiMasi JA, Brown JS. An analysis of regulatory review times of supplemental indications for already-approved drugs: 1989 to 1993. Drug Information Journal. 1996; 30(2):315-37.
  62. Brown JS, Bienz-Tadmor B, Lasagna L. Availability of anticancer drugs in the United States, Europe, and Japan from 1960 through 1991. Clin Pharmacol Ther. 1995 Sep; 58(3):243-56. PMID: 7554697.
    Citations: 1     Fields:    Translation:Humans
  63. Shulman SR, Brown JS. The Food and Drug Administration's early access and fast-track approval initiatives: how have they worked? Food Drug Law J. 1995; 50(4):503-31. PMID: 10343017.
    Citations: 1     Fields:    Translation:Humans
  64. Kaitin KI, Brown JS. A drug lag update. Drug Information Journal. 1995; 29:361-73.
  65. Bienz-Tadmor B, Brown JS. Biopharmaceuticals and conventional drugs: comparing development times. BioPharm. 1994; 7(2):44-9.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.