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Padraig Gerard Deighan, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang Erickson AF, Deighan P, Garcia CP, Weinzierl ROJ, Hochschild A, Losick R. An Amino Acid Substitution in RNA Polymerase That Inhibits the Utilization of an Alternative Sigma Factor. J Bacteriol. 2017 07 15; 199(14). PMID: 28507241.
    Citations:    Fields:    Translation:Cells
  2. Wang Erickson AF, Deighan P, Chen S, Barrasso K, Garcia CP, Martínez-Lumbreras S, Alfano C, Krysztofinska EM, Thapaliya A, Camp AH, Isaacson RL, Hochschild A, Losick R. A novel RNA polymerase-binding protein that interacts with a sigma-factor docking site. Mol Microbiol. 2017 Aug; 105(4):652-662. PMID: 28598017.
    Citations: 1     Fields:    Translation:Cells
  3. Baillargeon KR, Meserve K, Faulkner S, Watson S, Butts H, Deighan P, Gerdon AE. Precipitation SELEX: identification of DNA aptamers for calcium phosphate materials synthesis. Chem Commun (Camb). 2017 Jan 17; 53(6):1092-1095. PMID: 28045140.
    Citations:    Fields:    
  4. Wells CD, Deighan P, Brigham M, Hochschild A. Nascent RNA length dictates opposing effects of NusA on antitermination. Nucleic Acids Res. 2016 06 20; 44(11):5378-89. PMID: 27025650.
    Citations:    Fields:    Translation:Cells
  5. Javid B, Sorrentino F, Toosky M, Zheng W, Pinkham JT, Jain N, Pan M, Deighan P, Rubin EJ. Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1132-7. PMID: 24395793.
    Citations: 36     Fields:    Translation:Cells
  6. Montero-Diez C, Deighan P, Osmundson J, Darst SA, Hochschild A. Phage-encoded inhibitor of Staphylococcus aureus transcription exerts context-dependent effects on promoter function in a modified Escherichia coli-based transcription system. J Bacteriol. 2013 Aug; 195(16):3621-8. PMID: 23749973.
    Citations: 5     Fields:    Translation:Cells
  7. Huang L, Jin J, Deighan P, Kiner E, McReynolds L, Lieberman J. Efficient and specific gene knockdown by small interfering RNAs produced in bacteria. Nat Biotechnol. 2013 Apr; 31(4):350-6. PMID: 23475073.
    Citations: 15     Fields:    Translation:HumansCells
  8. Twist KA, Campbell EA, Deighan P, Nechaev S, Jain V, Geiduschek EP, Hochschild A, Darst SA. Crystal structure of the bacteriophage T4 late-transcription coactivator gp33 with the ß-subunit flap domain of Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):19961-6. PMID: 22135460.
    Citations: 5     Fields:    Translation:Cells
  9. Deighan P, Pukhrambam C, Nickels BE, Hochschild A. Initial transcribed region sequences influence the composition and functional properties of the bacterial elongation complex. Genes Dev. 2011 Jan 01; 25(1):77-88. PMID: 21205867.
    Citations: 17     Fields:    Translation:Cells
  10. Rao X, Deighan P, Hua Z, Hu X, Wang J, Luo M, Wang J, Liang Y, Zhong G, Hochschild A, Shen L. A regulator from Chlamydia trachomatis modulates the activity of RNA polymerase through direct interaction with the beta subunit and the primary sigma subunit. Genes Dev. 2009 Aug 01; 23(15):1818-29. PMID: 19651989.
    Citations: 16     Fields:    Translation:Cells
  11. Deighan P, Diez CM, Leibman M, Hochschild A, Nickels BE. The bacteriophage lambda Q antiterminator protein contacts the beta-flap domain of RNA polymerase. Proc Natl Acad Sci U S A. 2008 Oct 07; 105(40):15305-10. PMID: 18832144.
    Citations: 25     Fields:    Translation:Cells
  12. Deighan P, Hochschild A. The bacteriophage lambdaQ anti-terminator protein regulates late gene expression as a stable component of the transcription elongation complex. Mol Microbiol. 2007 Feb; 63(3):911-20. PMID: 17302807.
    Citations: 13     Fields:    Translation:Cells
  13. Deighan P, Hochschild A. Conformational toggle triggers a modulator of RNA polymerase activity. Trends Biochem Sci. 2006 Aug; 31(8):424-6. PMID: 16815708.
    Citations: 3     Fields:    Translation:Cells
  14. Hinde P, Deighan P, Dorman CJ. Characterization of the detachable Rho-dependent transcription terminator of the fimE gene in Escherichia coli K-12. J Bacteriol. 2005 Dec; 187(24):8256-66. PMID: 16321930.
    Citations: 7     Fields:    Translation:Cells
  15. Gregory BD, Deighan P, Hochschild A. An artificial activator that contacts a normally occluded surface of the RNA polymerase holoenzyme. J Mol Biol. 2005 Oct 28; 353(3):497-506. PMID: 16185714.
    Citations: 1     Fields:    Translation:Cells
  16. Beloin C, Deighan P, Doyle M, Dorman CJ. Shigella flexneri 2a strain 2457T expresses three members of the H-NS-like protein family: characterization of the Sfh protein. Mol Genet Genomics. 2003 Oct; 270(1):66-77. PMID: 12898223.
    Citations: 22     Fields:    Translation:Cells
  17. Deighan P, Beloin C, Dorman CJ. Three-way interactions among the Sfh, StpA and H-NS nucleoid-structuring proteins of Shigella flexneri 2a strain 2457T. Mol Microbiol. 2003 Jun; 48(5):1401-16. PMID: 12787365.
    Citations: 25     Fields:    Translation:Cells
  18. Dorman CJ, Deighan P. Regulation of gene expression by histone-like proteins in bacteria. Curr Opin Genet Dev. 2003 Apr; 13(2):179-84. PMID: 12672495.
    Citations: 75     Fields:    Translation:Cells
  19. Free A, Porter ME, Deighan P, Dorman CJ. Requirement for the molecular adapter function of StpA at the Escherichia coli bgl promoter depends upon the level of truncated H-NS protein. Mol Microbiol. 2001 Nov; 42(4):903-17. PMID: 11737635.
    Citations: 16     Fields:    Translation:Cells
  20. Deighan P, Free A, Dorman CJ. A role for the Escherichia coli H-NS-like protein StpA in OmpF porin expression through modulation of micF RNA stability. Mol Microbiol. 2000 Oct; 38(1):126-39. PMID: 11029695.
    Citations: 24     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.