Harvard Catalyst Profiles

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Ludy Chen Shih, M.D.

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Stanford University, Stanford, CABS06/1997Biological Sciences
UCLA School of Medicine, Los Angeles, CAMD05/2002Medicine
Beth Israel Deaconess Medical Center, Boston, MA06/2003Internship, Internal Medicine
Beth Israel Deaconess Medical Center, Boston, MA06/2006Residency, Neurology
Beth Israel Deaconess Medical Center, Boston, MA06/2007Fellowship, Movement Disorders
Harvard-MIT Health Sciences and Technology, Boston, MAMMSc06/2010Clinical Investigation
Alpha Omega Alpha Student Research Fellowship
American Stroke Association Student Scholarship in Cerebrovascular Disease
Carl and Edith Lasky Research Award
Richard D. Walter Award, UCLA Dept. of Neurology
Alpha Omega Alpha Honor Medical Society
2007 - 2008
Judith Goldberg Translational Research in Parkinson's Disease Grant
2008 - 2009
Harvard-MIT Clinical Investigator Training Program Fellowship

My clinical and research interests focus primarily on the use of deep brain stimulation for disorders of the basal ganglia. The primary conditions for which this therapy is used include dystonia, tremor and Parkinson's disease (PD). I am interested in characterization of circuitry of specific motor phenomenology in movement disorders, such as essential tremor and gait disorder associated with Parkinson's disease.

My clinical practice consists of evaluation and ongoing treatment of movement disorders including tremor, Parkinson's disease, and dystonia. In addition, I am the co-director of our multidisciplinary deep brain stimulation (DBS) program for movement disorders along with Ron Alterman, MD (neurosurgery).

Currently ongoing projects include a translational approach to gait analysis in human subjects with Parkinson's disease along with Dr. Veronique Vanderhorst. We are examining the utility and validity of measuring gait in a velocity-dependent manner in subjects with PD under various conditions.

Other projects under development noninvasive stimulation of the cerebellum for essential tremor, study of new investigational drugs for treatment of essential tremor and standardization of screening and outcomes guiding selection of patients for deep brain stimulation therapy. I am also involved in the planning of a nationwide registry for deep brain stimulation for Parkinson's disease.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.