Harvard Catalyst Profiles

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Michael Barry Brenner, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P01AI148102 (BRENNER, MICHAEL B.) Jun 15, 2021 - Mar 31, 2026
    NIH
    Differentiation of immune cells and fibrobalsts in inflamed tissue in RA and SLE
    Role: Principal Investigator
  2. R01AR073833 (BRENNER, MICHAEL B.) Aug 1, 2019 - Jul 31, 2024
    NIH
    Deciphering Pathways Driving Inflammatory Fibroblast Effector Functions in RA
    Role: Principal Investigator
  3. R21AI144139 (BRENNER, MICHAEL B.) Feb 20, 2019 - Jan 31, 2021
    NIH
    iNKT cells hyperactivate DCs
    Role: Principal Investigator
  4. R01AR073290 (BRENNER, MICHAEL B.) Sep 13, 2018 - Jun 30, 2023
    NIH
    Newly Identified T Peripheral Helper (Tph) Cells in Rheumatoid Arthritis
    Role: Principal Investigator
  5. R01AR063709 (BRENNER, MICHAEL B.) Feb 1, 2015 - Aug 31, 2026
    NIH
    Cadherin 11 Regulates Synovial Inflammation in Arthritis
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jonsson AH, Zhang F, Dunlap G, Gomez-Rivas E, Watts GFM, Faust HJ, Rupani KV, Mears JR, Meednu N, Wang R, Keras G, Coblyn JS, Massarotti EM, Todd DJ, Anolik JH, McDavid A, Wei K, Rao DA, Raychaudhuri S, Brenner MB. Granzyme K+ CD8 T cells form a core population in inflamed human tissue. Sci Transl Med. 2022 06 15; 14(649):eabo0686. PMID: 35704599.
    Citations:    Fields:    Translation:HumansCells
  2. Korsunsky I, Wei K, Pohin M, Kim EY, Barone F, Major T, Taylor E, Ravindran R, Kemble S, Watts GFM, Jonsson AH, Jeong Y, Athar H, Windell D, Kang JB, Friedrich M, Turner J, Nayar S, Fisher BA, Raza K, Marshall JL, Croft AP, Tamura T, Sholl LM, Vivero M, Rosas IO, Bowman SJ, Coles M, Frei AP, Lassen K, Filer A, Powrie F, Buckley CD, Brenner MB, Raychaudhuri S. Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases. Med (N Y). 2022 07 08; 3(7):481-518.e14. PMID: 35649411; PMCID: PMC9271637.
    Citations: 1     Translation:AnimalsCells
  3. Simmons DP, Nguyen HN, Gomez-Rivas E, Jeong Y, Jonsson AH, Chen AF, Lange JK, Dyer GS, Blazar P, Earp BE, Coblyn JS, Massarotti EM, Sparks JA, Todd DJ, Rao DA, Kim EY, Brenner MB. SLAMF7 engagement superactivates macrophages in acute and chronic inflammation. Sci Immunol. 2022 02 11; 7(68):eabf2846. PMID: 35148199; PMCID: PMC8991457.
    Citations: 1     Fields:    Translation:HumansCells
  4. Wei K, Nguyen HN, Brenner MB. Fibroblast pathology in inflammatory diseases. J Clin Invest. 2021 10 15; 131(20). PMID: 34651581; PMCID: PMC8516469.
    Citations: 5     Fields:    Translation:HumansCells
  5. Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML, Raychaudhuri S, Brenner MB, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Sci Adv. 2020 06; 6(26):eaba4353. PMID: 32637608; PMCID: PMC7319753.
    Citations: 8     Fields:    Translation:AnimalsCells
  6. LaMarche NM, Kane H, Kohlgruber AC, Dong H, Lynch L, Brenner MB. Distinct iNKT Cell Populations Use IFN? or ER Stress-Induced IL-10 to Control Adipose Tissue Homeostasis. Cell Metab. 2020 08 04; 32(2):243-258.e6. PMID: 32516575.
    Citations: 18     Fields:    Translation:AnimalsCells
  7. Kim EY, Ner-Gaon H, Varon J, Cullen AM, Guo J, Choi J, Barragan-Bradford D, Higuera A, Pinilla-Vera M, Short SA, Arciniegas-Rubio A, Tamura T, Leaf DE, Baron RM, Shay T, Brenner MB. Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-? in NK cells. J Clin Invest. 2020 06 01; 130(6):3238-3252. PMID: 32154791; PMCID: PMC7260006.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  8. Wei K, Korsunsky I, Marshall JL, Gao A, Watts GFM, Major T, Croft AP, Watts J, Blazar PE, Lange JK, Thornhill TS, Filer A, Raza K, Donlin LT, Siebel CW, Buckley CD, Raychaudhuri S, Brenner MB. Notch signalling drives synovial fibroblast identity and arthritis pathology. Nature. 2020 06; 582(7811):259-264. PMID: 32499639; PMCID: PMC7841716.
    Citations: 82     Fields:    Translation:HumansAnimalsCells
  9. Donado CA, Cao AB, Simmons DP, Croker BA, Brennan PJ, Brenner MB. A Two-Cell Model for IL-1ß Release Mediated by Death-Receptor Signaling. Cell Rep. 2020 04 07; 31(1):107466. PMID: 32268091.
    Citations: 11     Fields:    Translation:HumansAnimalsCells