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Dieter Manstein, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Müller M, Cascales JP, Marks HL, Wang-Evers M, Manstein D, Evans CL. Phosphorescent Microneedle Array for the Measurement of Oxygen Partial Pressure in Tissue. ACS Sens. 2022 Nov 25; 7(11):3440-3449. PMID: 36305608.
    Citations:    Fields:    Translation:Humans
  2. Salma N, Wang-Evers M, Casper MJ, Karasik D, Andrade YJ, Tannous Z, Manstein D. Mouse model of selective cryolipolysis. Lasers Surg Med. 2022 Jul 12. PMID: 35819225.
    Citations:    Fields:    
  3. Wang-Evers M, Blazon-Brown AJ, Ha-Wissel L, Arkhipova V, Paithankar D, Yaroslavsky IV, Altshuler G, Manstein D. Assessment of a 3050/3200 nm fiber laser system for ablative fractional laser treatments in dermatology. Lasers Surg Med. 2022 08; 54(6):851-860. PMID: 35395696; PMCID: PMC9541207.
    Citations:    Fields:    Translation:Humans
  4. Wang-Evers M, Casper MJ, Glahn J, Luo T, Doyle AE, Karasik D, Kim AC, Phothong W, Nathan NR, Heesakker T, Kositratna G, Manstein D. Assessing the impact of aging and blood pressure on dermal microvasculature by reactive hyperemia optical coherence tomography angiography. Sci Rep. 2021 06 28; 11(1):13411. PMID: 34183707; PMCID: PMC8238964.
    Citations:    Fields:    Translation:Humans
  5. Lo JA, Kawakubo M, Juneja VR, Su MY, Erlich TH, LaFleur MW, Kemeny LV, Rashid M, Malehmir M, Rabi SA, Raghavan R, Allouche J, Kasumova G, Frederick DT, Pauken KE, Weng QY, Pereira da Silva M, Xu Y, van der Sande AAJ, Silkworth W, Roider E, Browne EP, Lieb DJ, Wang B, Garraway LA, Wu CJ, Flaherty KT, Brinckerhoff CE, Mullins DW, Adams DJ, Hacohen N, Hoang MP, Boland GM, Freeman GJ, Sharpe AH, Manstein D, Fisher DE. Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses. Sci Transl Med. 2021 02 17; 13(581). PMID: 33597266.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  6. Nathan NR, O'Connor DM, Lee JJ, Cornejo KM, Tan JK, Tsao SS, Manstein D. Fractional Carbon Dioxide Laser Treatment for Textural Improvement and Symptomatic Relief of Acquired Cutis Laxa of the Neck. Lasers Surg Med. 2021 04; 53(4):427-428. PMID: 32770692.
    Citations:    Fields:    Translation:Humans
  7. Ha L, Jaspan M, Welford D, Evers M, Kositratna G, Casper MJ, Manstein D, Birngruber R. First Assessment of a Carbon Monoxide Laser and a Thulium Fiber Laser for Fractional Ablation of Skin. Lasers Surg Med. 2020 10; 52(8):788-798. PMID: 31943251.
    Citations: 1     Fields:    Translation:Humans
  8. Casper MJ, Glahn J, Evers M, Schulz-Hildebrandt H, Kositratna G, Birngruber R, Hüttmann G, Manstein D. Capillary Refill-The Key to Assessing Dermal Capillary Capacity and Pathology in Optical Coherence Tomography Angiography. Lasers Surg Med. 2020 09; 52(7):653-658. PMID: 31755127.
    Citations: 2     Fields:    Translation:Humans
  9. Kepp T, Droigk C, Casper M, Evers M, Hüttmann G, Salma N, Manstein D, Heinrich MP, Handels H. Segmentation of mouse skin layers in optical coherence tomography image data using deep convolutional neural networks. Biomed Opt Express. 2019 Jul 01; 10(7):3484-3496. PMID: 31467791; PMCID: PMC6706029.
    Citations: 10     
  10. Casper M, Schulz-Hildebrandt H, Evers M, Birngruber R, Manstein D, Hüttmann G. Optimization-based vessel segmentation pipeline for robust quantification of capillary networks in skin with optical coherence tomography angiography. J Biomed Opt. 2019 04; 24(4):1-11. PMID: 31041858.
    Citations: 5     Fields:    Translation:Humans
  11. Evers M, Salma N, Osseiran S, Casper M, Birngruber R, Evans CL, Manstein D. Enhanced quantification of metabolic activity for individual adipocytes by label-free FLIM. Sci Rep. 2018 06 08; 8(1):8757. PMID: 29884881.
    Citations: 7     Fields:    Translation:AnimalsCells
  12. Evers M, Ha L, Casper M, Welford D, Kositratna G, Birngruber R, Manstein D. Assessment of skin lesions produced by focused, tunable, mid-infrared chalcogenide laser radiation. Lasers Surg Med. 2018 09; 50(9):961-972. PMID: 29799127.
    Citations:    Fields:    Translation:Humans
  13. Sajjadi AY, Manstein D, Carp SA. Measuring Temperature Induced Phase Change Kinetics in Subcutaneous Adipose Tissues Using Near Infrared Spectroscopy, MR Imaging and Spectroscopy and OCT. Sci Rep. 2017 12 19; 7(1):17786. PMID: 29259284.
    Citations:    Fields:    Translation:HumansCells
  14. Kawakubo M, Cunningham TJ, Demehri S, Manstein D. Fractional Laser Releases Tumor-Associated Antigens in Poorly Immunogenic Tumor and Induces Systemic Immunity. Sci Rep. 2017 10 06; 7(1):12751. PMID: 28986576.
    Citations: 4     Fields:    Translation:AnimalsCells
  15. Kawakubo M, Demehri S, Manstein D. Fractional laser exposure induces neutrophil infiltration (N1 phenotype) into the tumor and stimulates systemic anti-tumor immune response. PLoS One. 2017; 12(9):e0184852. PMID: 28922374.
    Citations: 5     Fields:    Translation:AnimalsCells
  16. Trousil S, Chen S, Mu C, Shaw FM, Yao Z, Ran Y, Shakuntala T, Merghoub T, Manstein D, Rosen N, Cantley LC, Zippin JH, Zheng B. Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma. J Invest Dermatol. 2017 05; 137(5):1135-1143. PMID: 28143781; PMCID: PMC5392423.
    Citations: 9     Fields:    Translation:HumansCells
  17. Manstein D. Special dermatology/plastic surgery issue 2017. Lasers Surg Med. 2017 01; 49(1):3-6. PMID: 28129437.
    Citations:    Fields:    Translation:Humans
  18. Kositratna G, Hibert ML, Jaspan M, Welford D, Manstein D. Effects of deviation from focal plane on lesion geometry for ablative fractional photothermolysis. Lasers Surg Med. 2016 07; 48(5):555-61. PMID: 26842919.
    Citations:    Fields:    Translation:Humans
  19. Kositratna G, Evers M, Sajjadi A, Manstein D. Rapid fibrin plug formation within cutaneous ablative fractional CO2 laser lesions. Lasers Surg Med. 2016 Feb; 48(2):125-32. PMID: 26388136.
    Citations: 2     Fields:    Translation:HumansAnimals
  20. Erlendsson AM, Anderson RR, Manstein D, Waibel JS. Developing technology: ablative fractional lasers enhance topical drug delivery. Dermatol Surg. 2014 Dec; 40 Suppl 12:S142-6. PMID: 25417565.
    Citations: 3     Fields:    Translation:Humans
  21. Chen X, Kositratna G, Zhou C, Manstein D, Wu MX. Micro-fractional epidermal powder delivery for improved skin vaccination. J Control Release. 2014 Oct 28; 192:310-6. PMID: 25135790.
    Citations: 17     Fields:    Translation:HumansAnimalsPHPublic Health
  22. Mallidi S, Anbil S, Lee S, Manstein D, Elrington S, Kositratna G, Schoenfeld D, Pogue B, Davis SJ, Hasan T. Photosensitizer fluorescence and singlet oxygen luminescence as dosimetric predictors of topical 5-aminolevulinic acid photodynamic therapy induced clinical erythema. J Biomed Opt. 2014 Feb; 19(2):028001. PMID: 24503639.
    Citations: 15     Fields:    Translation:Humans
  23. Kim JE, Won CH, Bak H, Kositratna G, Manstein D, Dotto GP, Chang SE. Gene profiling analysis of the early effects of ablative fractional carbon dioxide laser treatment on human skin. Dermatol Surg. 2013 Jul; 39(7):1033-43. PMID: 23489371.
    Citations: 7     Fields:    Translation:HumansCells
  24. Chiu CY, Gomolka B, Dierkes C, Huang NR, Schroeder M, Purschke M, Manstein D, Dangi B, Weylandt KH. Erratum to: Omega-6 docosapentaenoic acid-derived resolvins and 17-hydroxydocosahexaenoic acid modulate macrophage function and alleviate experimental colitis. Inflamm Res. 2012 Nov; 61(11):1293. PMID: 22975931.
  25. Chuang GS, Manstein D, Tannous Z, Avram MM. Ulceration of mature surgical scars following nonablative fractional photothermolysis associated with intralesional lidocaine injections. Dermatol Surg. 2012 Nov; 38(11):1879-81. PMID: 22973818.
    Citations:    Fields:    Translation:Humans
  26. Peukert N, Bayer J, Becke D, Zurakowski D, Luger T, Manstein D, Laubach HJ. Fractional photothermolysis for the treatment of facial wrinkles - searching for optimal treatment parameters in a randomized study in the split-face design. J Dtsch Dermatol Ges. 2012 Dec; 10(12):898-904. PMID: 22776535.
    Citations:    Fields:    Translation:Humans
  27. Chiu CY, Gomolka B, Dierkes C, Huang NR, Schroeder M, Purschke M, Manstein D, Dangi B, Weylandt KH. Omega-6 docosapentaenoic acid-derived resolvins and 17-hydroxydocosahexaenoic acid modulate macrophage function and alleviate experimental colitis. Inflamm Res. 2012 Sep; 61(9):967-76. PMID: 22618200.
    Citations: 24     Fields:    Translation:AnimalsCells
  28. Chen X, Shah D, Kositratna G, Manstein D, Anderson RR, Wu MX. Facilitation of transcutaneous drug delivery and vaccine immunization by a safe laser technology. J Control Release. 2012 Apr 10; 159(1):43-51. PMID: 22261281.
    Citations: 29     Fields:    Translation:AnimalsPHPublic Health
  29. Purschke M, Anderson RR, Zurakowski D, Manstein D. Cell-cycle-dependent active thermal bystander effect (ATBE). Lasers Surg Med. 2011 Mar; 43(3):230-5. PMID: 21308697.
    Citations: 3     Fields:    Translation:HumansCells
  30. Thongsima S, Zurakowski D, Manstein D. Histological comparison of two different fractional photothermolysis devices operating at 1,550 nm. Lasers Surg Med. 2010 Jan; 42(1):32-7. PMID: 20077494.
    Citations: 1     Fields:    Translation:Humans
  31. Purschke M, Laubach HJ, Anderson RR, Manstein D. Thermal injury causes DNA damage and lethality in unheated surrounding cells: active thermal bystander effect. J Invest Dermatol. 2010 Jan; 130(1):86-92. PMID: 19587691.
    Citations: 20     Fields:    Translation:HumansCells
  32. Wanner M, Avram M, Gagnon D, Mihm MC, Zurakowski D, Watanabe K, Tannous Z, Anderson RR, Manstein D. Effects of non-invasive, 1,210 nm laser exposure on adipose tissue: results of a human pilot study. Lasers Surg Med. 2009 Aug; 41(6):401-7. PMID: 19588533.
    Citations: 2     Fields:    Translation:Humans
  33. Zelickson B, Egbert BM, Preciado J, Allison J, Springer K, Rhoades RW, Manstein D. Cryolipolysis for noninvasive fat cell destruction: initial results from a pig model. Dermatol Surg. 2009 Oct; 35(10):1462-70. PMID: 19614940.
    Citations: 36     Fields:    Translation:Animals
  34. Laubach HJ, Anderson RR, Luger T, Manstein D. Fractional photothermolysis for involuted infantile hemangioma. Arch Dermatol. 2009 Jul; 145(7):748-50. PMID: 19620554.
    Citations: 1     Fields:    Translation:Humans
  35. Laubach HJ, Astner S, Watanabe K, Clifford J, Rius-Diaz F, Zurakowski D, Manstein D. Effects of a 1,450 nm diode laser on facial sebum excretion. Lasers Surg Med. 2009 Feb; 41(2):110-5. PMID: 19226569.
    Citations: 5     Fields:    Translation:Humans
  36. Manstein D, Zurakowski D, Thongsima S, Laubach H, Chan HH. The effects of multiple passes on the epidermal thermal damage pattern in nonablative fractional resurfacing. Lasers Surg Med. 2009 Feb; 41(2):149-53. PMID: 19226571.
    Citations: 2     Fields:    Translation:Humans
  37. Manstein D, Laubach H, Watanabe K, Farinelli W, Zurakowski D, Anderson RR. Selective cryolysis: a novel method of non-invasive fat removal. Lasers Surg Med. 2008 Nov; 40(9):595-604. PMID: 18951424.
    Citations: 49     Fields:    Translation:Animals
  38. Laubach HJ, Makin IR, Barthe PG, Slayton MH, Manstein D. Intense focused ultrasound: evaluation of a new treatment modality for precise microcoagulation within the skin. Dermatol Surg. 2008 May; 34(5):727-34. PMID: 18429926.
    Citations: 17     Fields:    Translation:Humans
  39. Chan HH, Manstein D, Yu CS, Shek S, Kono T, Wei WI. The prevalence and risk factors of post-inflammatory hyperpigmentation after fractional resurfacing in Asians. Lasers Surg Med. 2007 Jun; 39(5):381-5. PMID: 17518354.
    Citations: 25     Fields:    Translation:Humans
  40. Kono T, Chan HH, Groff WF, Manstein D, Sakurai H, Takeuchi M, Yamaki T, Soejima K, Nozaki M. Prospective direct comparison study of fractional resurfacing using different fluences and densities for skin rejuvenation in Asians. Lasers Surg Med. 2007 Apr; 39(4):311-4. PMID: 17457835.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  41. Laubach HJ, Manstein D. [Fractional photothermolysis]. Hautarzt. 2007 Mar; 58(3):216-8, 220-3. PMID: 17318467.
    Citations: 2     Fields:    Translation:Humans
  42. Laubach H, Chan HH, Rius F, Anderson RR, Manstein D. Effects of skin temperature on lesion size in fractional photothermolysis. Lasers Surg Med. 2007 Jan; 39(1):14-8. PMID: 17252573.
    Citations: 3     Fields:    Translation:HumansCells
  43. Anderson RR, Farinelli W, Laubach H, Manstein D, Yaroslavsky AN, Gubeli J, Jordan K, Neil GR, Shinn M, Chandler W, Williams GP, Benson SV, Douglas DR, Dylla HF. Selective photothermolysis of lipid-rich tissues: a free electron laser study. Lasers Surg Med. 2006 Dec; 38(10):913-9. PMID: 17163478.
    Citations: 42     Fields:    Translation:HumansAnimals
  44. Laubach HJ, Tannous Z, Anderson RR, Manstein D. Skin responses to fractional photothermolysis. Lasers Surg Med. 2006 Feb; 38(2):142-9. PMID: 16392146.
    Citations: 53     Fields:    Translation:HumansCells
  45. Kono T, Manstein D, Chan HH, Nozaki M, Anderson RR. Q-switched ruby versus long-pulsed dye laser delivered with compression for treatment of facial lentigines in Asians. Lasers Surg Med. 2006 Feb; 38(2):94-7. PMID: 16265659.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  46. Willey A, Anderson RR, Azpiazu JL, Bakus AD, Barlow RJ, Dover JS, Garden JM, Kilmer SL, Landa N, Manstein D, Ross EV, Sadick N, Tanghetti EA, Yaghmai D, Zelickson BD. Complications of laser dermatologic surgery. Lasers Surg Med. 2006 Jan; 38(1):1-15. PMID: 16444692.
    Citations: 7     Fields:    Translation:Humans
  47. Khan MH, Sink RK, Manstein D, Eimerl D, Anderson RR. Intradermally focused infrared laser pulses: thermal effects at defined tissue depths. Lasers Surg Med. 2005 Apr; 36(4):270-80. PMID: 15719420.
    Citations: 20     Fields:    Translation:Humans
  48. Anderson, Manstein, Rokhsar, Tope and Dover . Fractional Resurfacing Forum. 2005.
  49. Khan MH, Sink RK, Manstein D, Eimerl D, Anderson RR. Intradermally focused infrared laser pulses: Thermal effects at defined tissue depths. . Lasers Surg Med. 2005.
  50. Method and apparatus for dermatological treatment and fractional skin resurfacing. 2004.
  51. . Method and apparatus for photothermal treatment of tissue at depth. 2004.
  52. Method and apparatus for hair growth management . 2004.
  53. Manstein D, Herron GS, Sink RK, Tanner H, Anderson RR. Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury. Lasers Surg Med. 2004; 34(5):426-38. PMID: 15216537.
    Citations: 162     Fields:    Translation:HumansCTClinical Trials
  54. Methods and devices for selective disruption of fatty tissue by controlled cooling. 2003.
  55. Method and apparatus for the selective targeting Method and apparatus for the selective targeting of lipid-rich tissues . 2003.
  56. Method and apparatus for EMR treatment (island of damage) . 2002.
  57. Method and apparatus for medical treatment utilizing long duration electromagnetic radiation. 2002.
  58. Altshuler GB, Anderson RR, Manstein D, Zenzie HH, Smirnov MZ. Extended theory of selective photothermolysis. Lasers Surg Med. 2001; 29(5):416-32. PMID: 11891730.
    Citations: 36     Fields:    Translation:Humans
  59. Altshuler GB, Anderson RR, Manstein D, Zenzie HH, Smirnov MZ. Extended theory of selective photothermolysis. Laser Surg Med. 2001; 29(5):416-432.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.