Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Gerhard Wagner, Ph.D.

Co-Author

This page shows the publications co-authored by Gerhard Wagner and Haribabu Arthanari.
Connection Strength

8.439
  1. Emerging solution NMR methods to illuminate the structural and dynamic properties of proteins. Curr Opin Struct Biol. 2019 10; 58:294-304.
    View in: PubMed
    Score: 0.856
  2. VirtualFlow Ants-Ultra-Large Virtual Screenings with Artificial Intelligence Driven Docking Algorithm Based on Ant Colony Optimization. Int J Mol Sci. 2021 May 28; 22(11).
    View in: PubMed
    Score: 0.243
  3. A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders. Eur J Med Chem. 2021 Jul 05; 219:113435.
    View in: PubMed
    Score: 0.241
  4. A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening. iScience. 2021 Feb 19; 24(2):102021.
    View in: PubMed
    Score: 0.237
  5. Nearest-neighbor NMR spectroscopy: categorizing spectral peaks by their adjacent nuclei. Nat Commun. 2020 11 03; 11(1):5547.
    View in: PubMed
    Score: 0.234
  6. A Multi-Pronged Approach Targeting SARS-CoV-2 Proteins Using Ultra-Large Virtual Screening. ChemRxiv. 2020 Jul 24.
    View in: PubMed
    Score: 0.229
  7. The precious fluorine on the ring: fluorine NMR for biological systems. J Biomol NMR. 2020 Sep; 74(8-9):365-379.
    View in: PubMed
    Score: 0.229
  8. An open-source drug discovery platform enables ultra-large virtual screens. Nature. 2020 04; 580(7805):663-668.
    View in: PubMed
    Score: 0.224
  9. Aromatic 19F-13C TROSY: a background-free approach to probe biomolecular structure, function, and dynamics. Nat Methods. 2019 04; 16(4):333-340.
    View in: PubMed
    Score: 0.209
  10. Nonuniform Sampling for NMR Spectroscopy. Methods Enzymol. 2019; 614:263-291.
    View in: PubMed
    Score: 0.203
  11. Optimal control theory enables homonuclear decoupling without Bloch-Siegert shifts in NMR spectroscopy. Nat Commun. 2018 08 01; 9(1):3014.
    View in: PubMed
    Score: 0.200
  12. 15N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteins. Proc Natl Acad Sci U S A. 2018 02 20; 115(8):E1710-E1719.
    View in: PubMed
    Score: 0.193
  13. Mixed pyruvate labeling enables backbone resonance assignment of large proteins using a single experiment. Nat Commun. 2018 01 24; 9(1):356.
    View in: PubMed
    Score: 0.193
  14. Erratum to: Nitrogen detected TROSY at high field yields high resolution and sensitivity for protein NMR. J Biomol NMR. 2017 12; 69(4):245.
    View in: PubMed
    Score: 0.191
  15. NMR-directed design of pre-TCRß and pMHC molecules implies a distinct geometry for pre-TCR relative to aßTCR recognition of pMHC. J Biol Chem. 2018 01 19; 293(3):754-766.
    View in: PubMed
    Score: 0.190
  16. Rapid convergence of optimal control in NMR using numerically-constructed toggling frames. J Magn Reson. 2017 08; 281:94-103.
    View in: PubMed
    Score: 0.184
  17. Perspective: revisiting the field dependence of TROSY sensitivity. J Biomol NMR. 2016 12; 66(4):221-225.
    View in: PubMed
    Score: 0.178
  18. Analytical optimization of active bandwidth and quality factor for TOCSY experiments in NMR spectroscopy. J Biomol NMR. 2016 09; 66(1):9-20.
    View in: PubMed
    Score: 0.175
  19. Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction. Nature. 2016 Feb 25; 530(7591):485-9.
    View in: PubMed
    Score: 0.169
  20. Nitrogen detected TROSY at high field yields high resolution and sensitivity for protein NMR. J Biomol NMR. 2015 Dec; 63(4):323-331.
    View in: PubMed
    Score: 0.165
  21. Backbone resonance assignment of N15, N30 and D10 T cell receptor ß subunits. Biomol NMR Assign. 2016 Apr; 10(1):35-9.
    View in: PubMed
    Score: 0.163
  22. Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):9010-5.
    View in: PubMed
    Score: 0.162
  23. eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference. Nat Commun. 2015 May 28; 6:7194.
    View in: PubMed
    Score: 0.161
  24. Increased resolution of aromatic cross peaks using alternate 13C labeling and TROSY. J Biomol NMR. 2015 Jul; 62(3):291-301.
    View in: PubMed
    Score: 0.160
  25. Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):E3187-95.
    View in: PubMed
    Score: 0.151
  26. A new broadband homonuclear mixing pulse for NMR with low applied power. J Chem Phys. 2014 Jul 14; 141(2):024201.
    View in: PubMed
    Score: 0.151
  27. Selective methyl labeling of eukaryotic membrane proteins using cell-free expression. J Am Chem Soc. 2014 Aug 13; 136(32):11308-10.
    View in: PubMed
    Score: 0.151
  28. Perspectives in magnetic resonance: NMR in the post-FFT era. J Magn Reson. 2014 Apr; 241:60-73.
    View in: PubMed
    Score: 0.148
  29. Resonance assignments of the microtubule-binding domain of the C. elegans spindle and kinetochore-associated protein 1. Biomol NMR Assign. 2014 Oct; 8(2):275-8.
    View in: PubMed
    Score: 0.140
  30. The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2ß. Cell Rep. 2012 Jun 28; 1(6):689-702.
    View in: PubMed
    Score: 0.130
  31. Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling. J Biomol NMR. 2012 Apr; 52(4):315-27.
    View in: PubMed
    Score: 0.128
  32. Applications of non-uniform sampling and processing. Top Curr Chem. 2012; 316:125-48.
    View in: PubMed
    Score: 0.127
  33. Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly. J Biol Chem. 2011 Dec 23; 286(51):44266-44276.
    View in: PubMed
    Score: 0.125
  34. Optimal pulse design in quantum control: a unified computational method. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):1879-84.
    View in: PubMed
    Score: 0.119
  35. Heteronuclear decoupling by multiple rotating frame technique. J Magn Reson. 2011 Mar; 209(1):8-18.
    View in: PubMed
    Score: 0.118
  36. Time-shared HSQC-NOESY for accurate distance constraints measured at high-field in (15)N-(13)C-ILV methyl labeled proteins. J Biomol NMR. 2009 Nov; 45(3):311-8.
    View in: PubMed
    Score: 0.109
  37. A double TROSY hNCAnH experiment for efficient assignment of large and challenging proteins. J Am Chem Soc. 2009 Sep 16; 131(36):12880-1.
    View in: PubMed
    Score: 0.108
  38. FM reconstruction of non-uniformly sampled protein NMR data at higher dimensions and optimization by distillation. J Biomol NMR. 2009 Nov; 45(3):283-94.
    View in: PubMed
    Score: 0.108
  39. The T-lock: automated compensation of radio-frequency induced sample heating. J Biomol NMR. 2009 Jun; 44(2):69-76.
    View in: PubMed
    Score: 0.106
  40. Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase. Nature. 2008 Aug 14; 454(7206):903-6.
    View in: PubMed
    Score: 0.100
  41. Unambiguous assignment of NMR protein backbone signals with a time-shared triple-resonance experiment. J Biomol NMR. 2005 Nov; 33(3):187-96.
    View in: PubMed
    Score: 0.083
  42. Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin. Endocrinology. 2021 02 01; 162(2).
    View in: PubMed
    Score: 0.060
  43. Pre-T cell receptors topologically sample self-ligands during thymocyte ß-selection. Science. 2021 01 08; 371(6525):181-185.
    View in: PubMed
    Score: 0.059
  44. NMR: an essential structural tool for integrative studies of T cell development, pMHC ligand recognition and TCR mechanobiology. J Biomol NMR. 2019 Jul; 73(6-7):319-332.
    View in: PubMed
    Score: 0.052
  45. The T Cell Antigen Receptor a Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations. Immunity. 2018 11 20; 49(5):829-841.e6.
    View in: PubMed
    Score: 0.051
  46. Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major. Nucleic Acids Res. 2018 04 20; 46(7):3791-3801.
    View in: PubMed
    Score: 0.049
  47. 1H, 13C, and 15N backbone chemical shift assignments of 4E-BP144-87 and 4E-BP144-87 bound to eIF4E. Biomol NMR Assign. 2017 Oct; 11(2):187-191.
    View in: PubMed
    Score: 0.046
  48. Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5. Cell Rep. 2017 03 14; 18(11):2651-2663.
    View in: PubMed
    Score: 0.045
  49. Identification of DNA primase inhibitors via a combined fragment-based and virtual screening. Sci Rep. 2016 11 02; 6:36322.
    View in: PubMed
    Score: 0.044
  50. Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins. PLoS One. 2016; 11(9):e0163660.
    View in: PubMed
    Score: 0.044
  51. Nitrogen-detected TROSY yields comparable sensitivity to proton-detected TROSY for non-deuterated, large proteins under physiological salt conditions. J Biomol NMR. 2016 Feb; 64(2):143-51.
    View in: PubMed
    Score: 0.042
  52. Structure of a CGI-58 motif provides the molecular basis of lipid droplet anchoring. J Biol Chem. 2015 Oct 30; 290(44):26361-72.
    View in: PubMed
    Score: 0.041
  53. Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1. Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):E4036-45.
    View in: PubMed
    Score: 0.040
  54. Pre-TCR ligand binding impacts thymocyte development before aßTCR expression. Proc Natl Acad Sci U S A. 2015 Jul 07; 112(27):8373-8.
    View in: PubMed
    Score: 0.040
  55. An RNA-binding Protein, Lin28, Recognizes and Remodels G-quartets in the MicroRNAs (miRNAs) and mRNAs It Regulates. J Biol Chem. 2015 Jul 17; 290(29):17909-17922.
    View in: PubMed
    Score: 0.040
  56. Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments. J Biol Chem. 2014 Jul 04; 289(27):18880-92.
    View in: PubMed
    Score: 0.037
  57. The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes. Biochemistry. 2013 Dec 31; 52(52):9510-8.
    View in: PubMed
    Score: 0.036
  58. Pulse design for broadband correlation NMR spectroscopy by multi-rotating frames. J Biomol NMR. 2013 Mar; 55(3):291-302.
    View in: PubMed
    Score: 0.034
  59. The kinetochore-bound Ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments. Dev Cell. 2012 Nov 13; 23(5):968-80.
    View in: PubMed
    Score: 0.033
  60. Complexes of native ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants. J Am Chem Soc. 2011 Nov 09; 133(44):17681-95.
    View in: PubMed
    Score: 0.031
  61. Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability. J Am Chem Soc. 2010 Dec 15; 132(49):17411-25.
    View in: PubMed
    Score: 0.029
  62. Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p. J Biol Chem. 2009 Feb 13; 284(7):4422-8.
    View in: PubMed
    Score: 0.026
  63. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature. 2008 Apr 03; 452(7187):604-9.
    View in: PubMed
    Score: 0.024
  64. CTL recognition of a protective immunodominant influenza A virus nucleoprotein epitope utilizes a highly restricted Vbeta but diverse Valpha repertoire: functional and structural implications. J Mol Biol. 2007 Sep 14; 372(2):535-48.
    View in: PubMed
    Score: 0.023
  65. Synthetic studies toward aryl-(4-aryl-4H-[1,2,4]triazole-3-yl)-amine from 1,3-diarylthiourea as urea mimetics. J Org Chem. 2005 Aug 05; 70(16):6362-8.
    View in: PubMed
    Score: 0.020
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.