Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Steven P. Gygi, Ph.D.

Co-Author

This page shows the publications co-authored by Steven Gygi and Daniel Finley.
Connection Strength

2.766
  1. Global proteomics of Ubqln2-based murine models of ALS. J Biol Chem. 2020 Dec 04.
    View in: PubMed
    Score: 0.242
  2. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. J Biol Chem. 2017 11 24; 292(47):19209-19225.
    View in: PubMed
    Score: 0.194
  3. UBE2O remodels the proteome during terminal erythroid differentiation. Science. 2017 08 04; 357(6350).
    View in: PubMed
    Score: 0.192
  4. Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes. Cell Syst. 2016 10 26; 3(4):395-403.e4.
    View in: PubMed
    Score: 0.181
  5. USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites. Nature. 2016 Apr 21; 532(7599):398-401.
    View in: PubMed
    Score: 0.175
  6. Multiplexed, Proteome-Wide Protein Expression Profiling: Yeast Deubiquitylating Enzyme Knockout Strains. J Proteome Res. 2015 Dec 04; 14(12):5306-17.
    View in: PubMed
    Score: 0.170
  7. Cuz1/Ynl155w, a zinc-dependent ubiquitin-binding protein, protects cells from metalloid-induced proteotoxicity. J Biol Chem. 2014 Jan 17; 289(3):1876-85.
    View in: PubMed
    Score: 0.149
  8. An asymmetric interface between the regulatory and core particles of the proteasome. Nat Struct Mol Biol. 2011 Oct 30; 18(11):1259-67.
    View in: PubMed
    Score: 0.129
  9. Structural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress response. J Biol Chem. 2011 Oct 21; 286(42):36652-66.
    View in: PubMed
    Score: 0.127
  10. Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature. 2010 Sep 09; 467(7312):179-84.
    View in: PubMed
    Score: 0.119
  11. Chaperone-mediated pathway of proteasome regulatory particle assembly. Nature. 2009 Jun 11; 459(7248):861-5.
    View in: PubMed
    Score: 0.109
  12. Hexameric assembly of the proteasomal ATPases is templated through their C termini. Nature. 2009 Jun 11; 459(7248):866-70.
    View in: PubMed
    Score: 0.109
  13. Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities. Cell. 2006 Dec 29; 127(7):1401-13.
    View in: PubMed
    Score: 0.092
  14. Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation. Cell. 2006 Oct 06; 127(1):99-111.
    View in: PubMed
    Score: 0.091
  15. Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology. Nat Cell Biol. 2006 Jul; 8(7):700-10.
    View in: PubMed
    Score: 0.089
  16. The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle. Nat Struct Mol Biol. 2005 Apr; 12(4):294-303.
    View in: PubMed
    Score: 0.081
  17. A proteomics approach to understanding protein ubiquitination. Nat Biotechnol. 2003 Aug; 21(8):921-6.
    View in: PubMed
    Score: 0.072
  18. Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis. Nat Struct Mol Biol. 2021 May; 28(5):418-425.
    View in: PubMed
    Score: 0.062
  19. Membrane skeleton modulates erythroid proteome remodeling and organelle clearance. Blood. 2021 01 21; 137(3):398-409.
    View in: PubMed
    Score: 0.061
  20. Chromatin accessibility promotes hematopoietic and leukemia stem cell activity. Nat Commun. 2020 03 16; 11(1):1406.
    View in: PubMed
    Score: 0.057
  21. Thiol-based direct threat sensing by the stress-activated protein kinase Hog1. Sci Signal. 2019 11 26; 12(609).
    View in: PubMed
    Score: 0.056
  22. Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia. Blood. 2018 11 29; 132(22):2375-2388.
    View in: PubMed
    Score: 0.052
  23. Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins. Elife. 2017 09 21; 6.
    View in: PubMed
    Score: 0.048
  24. Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals. J Cell Biol. 2017 07 03; 216(7):2027-2045.
    View in: PubMed
    Score: 0.047
  25. APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1. Nat Cell Biol. 2012 Jan 29; 14(2):168-76.
    View in: PubMed
    Score: 0.033
  26. Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome. Mol Cell. 2010 Jun 11; 38(5):733-45.
    View in: PubMed
    Score: 0.029
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.