Harvard Catalyst Profiles

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Dominic M. Walsh, Ph.D.

Co-Author

This page shows the publications co-authored by Dominic Walsh and Matthew Frosch.
Connection Strength

1.609
  1. Corbett GT, Wang Z, Hong W, Colom-Cadena M, Rose J, Liao M, Asfaw A, Hall TC, Ding L, DeSousa A, Frosch MP, Collinge J, Harris DA, Perkinton MS, Spires-Jones TL, Young-Pearse TL, Billinton A, Walsh DM. PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins. Acta Neuropathol. 2020 Mar; 139(3):503-526.
    View in: PubMed
    Score: 0.241
  2. Brinkmalm G, Hong W, Wang Z, Liu W, O'Malley TT, Sun X, Frosch MP, Selkoe DJ, Portelius E, Zetterberg H, Blennow K, Walsh DM. Identification of neurotoxic cross-linked amyloid-ß dimers in the Alzheimer's brain. Brain. 2019 05 01; 142(5):1441-1457.
    View in: PubMed
    Score: 0.231
  3. Mengel D, Hong W, Corbett GT, Liu W, DeSousa A, Solforosi L, Fang C, Frosch MP, Collinge J, Harris DA, Walsh DM. PrP-grafted antibodies bind certain amyloid ß-protein aggregates, but do not prevent toxicity. Brain Res. 2019 05 01; 1710:125-135.
    View in: PubMed
    Score: 0.225
  4. Jin M, O'Nuallain B, Hong W, Boyd J, Lagomarsino VN, O'Malley TT, Liu W, Vanderburg CR, Frosch MP, Young-Pearse T, Selkoe DJ, Walsh DM. An in vitro paradigm to assess potential anti-Aß antibodies for Alzheimer's disease. Nat Commun. 2018 07 11; 9(1):2676.
    View in: PubMed
    Score: 0.218
  5. Hong W, Wang Z, Liu W, O'Malley TT, Jin M, Willem M, Haass C, Frosch MP, Walsh DM. Diffusible, highly bioactive oligomers represent a critical minority of soluble Aß in Alzheimer's disease brain. Acta Neuropathol. 2018 07; 136(1):19-40.
    View in: PubMed
    Score: 0.215
  6. Wang Z, Jackson RJ, Hong W, Taylor WM, Corbett GT, Moreno A, Liu W, Li S, Frosch MP, Slutsky I, Young-Pearse TL, Spires-Jones TL, Walsh DM. Human Brain-Derived Aß Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP. J Neurosci. 2017 12 06; 37(49):11947-11966.
    View in: PubMed
    Score: 0.208
  7. Mc Donald JM, O'Malley TT, Liu W, Mably AJ, Brinkmalm G, Portelius E, Wittbold WM, Frosch MP, Walsh DM. The aqueous phase of Alzheimer's disease brain contains assemblies built from ~4 and ~7 kDa Aß species. Alzheimers Dement. 2015 Nov; 11(11):1286-305.
    View in: PubMed
    Score: 0.174
  8. Zott B, Simon MM, Hong W, Unger F, Chen-Engerer HJ, Frosch MP, Sakmann B, Walsh DM, Konnerth A. A vicious cycle of ß amyloid-dependent neuronal hyperactivation. Science. 2019 08 09; 365(6453):559-565.
    View in: PubMed
    Score: 0.059
  9. Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP, Selkoe DJ. Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron. 2003 Dec 18; 40(6):1087-93.
    View in: PubMed
    Score: 0.020
  10. Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ. The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease. Neuron. 2003 Feb 20; 37(4):583-95.
    View in: PubMed
    Score: 0.019
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.