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profileOrhun Muratoglu, PH.D.

TitleProfessor of Orthopedic Surgery
InstitutionMassachusetts General Hospital
DepartmentOrthopedic Surgery
AddressMassachusetts General Hospital
Orthopedic Biomechanics Lab, Jackson 1206
55 Fruit St
Boston MA 02114
Phone617/726-3869
Fax617/726-3883
vCardDownload vCard (login for email)

Collapse Mentoring 
Collapse completed student projects
The Effect of Molecular Ultrastructure on the Cross-Link Density and Mechanical Properties of Irradiated Polyethylene Polymers
Summer, 06/23/99 - 09/01/99

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01AR051142     (MURATOGLU, ORHUN K)Apr 1, 2004 - Mar 31, 2008
NIH/NIAMS
Fatigue Resistant Crosslinked UHMWPE for Total Joints
Role: Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Oral E, Fung M, Rowell SL, Muratoglu OK. An In-Vitro Oxidation Model for UHMWPE incorporating synovial fluid lipids. J Orthop Res. 2018 Jan 04. PMID: 29314179.
    View in: PubMed
  2. Xu JZ, Wannomae KK, Muratoglu OK, Oral E. Increased oxidative protection by high active vitamin E content and partial radiation crosslinking of UHMWPE. J Orthop Res. 2017 Dec 12. PMID: 29232007.
    View in: PubMed
  3. Laaksonen I, Galea VP, Connelly JW, Matuszak SJ, Muratoglu OK, Malchau H. Inferior Radiographic and Functional Outcomes With Modular Stem in Metal-on-Metal Total Hip Arthroplasty. J Arthroplasty. 2017 Sep 06. PMID: 28947371.
    View in: PubMed
  4. Chen W, Bichara DA, Suhardi J, Sheng P, Muratoglu OK. Effects of vitamin E-diffused highly cross-linked UHMWPE particles on inflammation, apoptosis and immune response against S. aureus. Biomaterials. 2017 Oct; 143:46-56. PMID: 28759874.
    View in: PubMed
  5. Senthil-Kumar P, Ng-Glazier JH, Randolph MA, Bodugoz-Senturk H, Muratoglu OK, Kochevar IE, Winograd JM, Redmond RW. An intraluminal stent facilitates light-activated vascular anastomosis. J Trauma Acute Care Surg. 2017 Jul; 83(1 Suppl 1):S43-S49. PMID: 28383474.
    View in: PubMed
  6. Gul RM, Fung K, Doshi BN, Oral E, Muratoglu OK. Surface cross-linked UHMWPE using peroxides. J Orthop Res. 2017 11; 35(11):2551-2556. PMID: 28374917.
    View in: PubMed
  7. Donahue GS, Lindgren V, Galea VP, Madanat R, Muratoglu OK, Malchau H. Risk factors for mid-term revision surgery in patients with articular surface replacement total hip arthroplasty. Hip Int. 2017 May 27; 0. PMID: 28574125.
    View in: PubMed
  8. Galea VP, Laaksonen I, Matuszak SJ, Connelly JW, Muratoglu O, Malchau H. Mid-term changes in blood metal ion levels after Articular Surface Replacement arthroplasty of the hip. Bone Joint J. 2017 Apr; 99-B(4 Supple B):33-40. PMID: 28363892.
    View in: PubMed
  9. Hussey DK, Madanat R, Donahue GS, Rolfson O, Bragdon CR, Muratoglu OK, Malchau H. Scoring the Current Risk Stratification Guidelines in Follow-up Evaluation of Patients After Metal-on-Metal Hip Arthroplasty: A Proposal for a Metal-on-Metal Risk Score Supporting Clinical Decision-Making. J Bone Joint Surg Am. 2016 Nov 16; 98(22):1905-1912. PMID: 27852907.
    View in: PubMed
  10. Zumbrunn T, Duffy MP, Rubash HE, Malchau H, Muratoglu OK, Varadarajan KM. ACL substitution may improve kinematics of PCL-retaining total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2016 Nov 11. PMID: 27837219.
    View in: PubMed
  11. Muratoglu OK. CORR Insights®: A Novel Technique for Assessing Antioxidant Concentration in Retrieved UHMWPE. Clin Orthop Relat Res. 2017 05; 475(5):1366-1368. PMID: 27637613.
    View in: PubMed
  12. Oral E, O'Brien C, Doshi B, Muratoglu OK. High temperature homogenization improves impact toughness of vitamin E-diffused, irradiated UHMWPE. J Orthop Res. 2017 06; 35(6):1343-1347. PMID: 27487014.
    View in: PubMed
  13. Hussey DK, Madanat R, Donahue GS, Rolfson O, Muratoglu OK, Malchau H. Worse health-related quality of life and hip function in female patients with elevated chromium levels. Acta Orthop. 2016 Oct; 87(5):485-91. PMID: 27459602; PMCID: PMC5016907 [Available on 10/01/16].
  14. Donahue GS, Lindgren V, Galea VP, Madanat R, Muratoglu O, Malchau H. Are Females at Greater Risk for Revision Surgery After Hip Resurfacing Arthroplasty With the Articular Surface Replacement Prosthesis? Clin Orthop Relat Res. 2016 Oct; 474(10):2257-65. PMID: 27121872.
    View in: PubMed
  15. Oral E, Doshi BN, Gul RM, Neils AL, Kayandan S, Muratoglu OK. Peroxide cross-linked UHMWPE blended with vitamin E. J Biomed Mater Res B Appl Biomater. 2017 Aug; 105(6):1379-1389. PMID: 27080171.
    View in: PubMed
  16. Madanat R, Rolfson O, Donahue GS, Hussey DK, Potter HG, Wallace R, Muratoglu OK, Malchau H. Medial Calcar Erosion Is Associated With Synovial Thickness in Patients With ASR XL Total Hip Arthroplasty. J Arthroplasty. 2016 11; 31(11):2588-2592. PMID: 27178012.
    View in: PubMed
  17. Doshi B, Ward JS, Oral E, Muratoglu OK. Fatigue toughness of irradiated vitamin E/UHMWPE blends. J Orthop Res. 2016 09; 34(9):1514-20. PMID: 26773556.
    View in: PubMed
  18. Nebergall AK, Freiberg AA, Greene ME, Malchau H, Muratoglu O, Rowell S, Zumbrunn T, Varadarajan KM. Analysis of Dual Mobility Liner Rim Damage Using Retrieved Components and Cadaver Models. J Arthroplasty. 2016 07; 31(7):1595-602. PMID: 26796773.
    View in: PubMed
  19. Ling D, Bodugoz-Senturk H, Nanda S, Braithwaite G, Muratoglu OK. Quantifying the lubricity of mechanically tough polyvinyl alcohol hydrogels for cartilage repair. Proc Inst Mech Eng H. 2015 Dec; 229(12):845-52. PMID: 26614798.
    View in: PubMed
  20. Varadarajan KM, Zumbrunn T, Duffy MP, Patel R, Freiberg AA, Rubash HE, Malchau H, Muratoglu OK. Reducing the distal profile of dual mobility liners can mitigate soft-tissue impingement and liner entrapment without affecting mechanical performance. J Orthop Res. 2016 05; 34(5):889-97. PMID: 26496522.
    View in: PubMed
  21. Langlois J, Zaoui A, Bichara DA, Nich C, Bensidhoum M, Petite H, Muratoglu OK, Hamadouche M. Biological reaction to polyethylene particles in a murine calvarial model is highly influenced by age. J Orthop Res. 2016 Apr; 34(4):574-80. PMID: 26375608.
    View in: PubMed
  22. Madanat R, Hussey DK, Donahue GS, Potter HG, Wallace R, Bragdon C, Muratoglu O, Malchau H. Early Lessons From a Worldwide, Multicenter, Followup Study of the Recalled Articular Surface Replacement Hip System. Clin Orthop Relat Res. 2016 Jan; 474(1):166-74. PMID: 26310677; PMCID: PMC4686517 [Available on 01/01/17].
  23. Varadarajan KM, Zumbrunn T, Rubash HE, Malchau H, Muratoglu OK, Li G. Reverse Engineering Nature to Design Biomimetic Total Knee Implants. J Knee Surg. 2015 Oct; 28(5):363-9. PMID: 26166428.
    View in: PubMed
  24. de Steiger RN, Muratoglu O, Lorimer M, Cuthbert AR, Graves SE. Lower prosthesis-specific 10-year revision rate with crosslinked than with non-crosslinked polyethylene in primary total knee arthroplasty. Acta Orthop. 2015; 86(6):721-7. PMID: 26119884; PMCID: PMC4750773.
  25. Zumbrunn T, Varadarajan KM, Rubash HE, Malchau H, Li G, Muratoglu OK. Regaining Native Knee Kinematics Following Joint Arthroplasty: A Novel Biomimetic Design with ACL and PCL Preservation. J Arthroplasty. 2015 Dec; 30(12):2143-8. PMID: 26195354.
    View in: PubMed
  26. Varadarajan KM, Zumbrunn T, Rubash HE, Malchau H, Li G, Muratoglu OK. Cruciate Retaining Implant With Biomimetic Articular Surface to Reproduce Activity Dependent Kinematics of the Normal Knee. J Arthroplasty. 2015 Dec; 30(12):2149-53.e2. PMID: 26154569.
    View in: PubMed
  27. Rowell SL, Muratoglu OK. Investigation of surgically retrieved, vitamin E-stabilized, crosslinked UHMWPE implants after short-term in vivo service. J Biomed Mater Res B Appl Biomater. 2016 08; 104(6):1132-40. PMID: 26039944.
    View in: PubMed
  28. Madanat R, Hussey DK, Donahue GS, Potter HG, Wallace R, Bragdon CR, Muratoglu OK, Malchau H. The Symmetry of Adverse Local Tissue Reactions in Patients with Bilateral Simultaneous and Sequential ASR Hip Replacement. J Arthroplasty. 2015 Oct; 30(10):1794-8. PMID: 26055146.
    View in: PubMed
  29. Rowell SL, Reyes CR, Malchau H, Muratoglu OK. In Vivo Oxidative Stability Changes of Highly Cross-Linked Polyethylene Bearings: An Ex Vivo Investigation. J Arthroplasty. 2015 Oct; 30(10):1828-34. PMID: 26048729.
    View in: PubMed
  30. Dion NT, Bragdon C, Muratoglu O, Freiberg AA. Durability of highly cross-linked polyethylene in total hip and total knee arthroplasty. Orthop Clin North Am. 2015 Jul; 46(3):321-7, ix. PMID: 26043046.
    View in: PubMed
  31. Oral E, Neils AL, Doshi BN, Fu J, Muratoglu OK. Effects of simulated oxidation on the in vitro wear and mechanical properties of irradiated and melted highly crosslinked UHMWPE. J Biomed Mater Res B Appl Biomater. 2016 Feb; 104(2):316-22. PMID: 25766106.
    View in: PubMed
  32. Zeng X, Zou L, Levine RA, Guerrero JL, Handschumacher MD, Sullivan SM, Braithwaite GJC, Stone JR, Solis J, Muratoglu OK, Vlahakes GJ, Hung J. Efficacy of polymer injection for ischemic mitral regurgitation: persistent reduction of mitral regurgitation and attenuation of left ventricular remodeling. JACC Cardiovasc Interv. 2015 Feb; 8(2):355-363. PMID: 25596792.
    View in: PubMed
  33. Oral E, Neils A, Muratoglu OK. High vitamin E content, impact resistant UHMWPE blend without loss of wear resistance. J Biomed Mater Res B Appl Biomater. 2015 May; 103(4):790-7. PMID: 25115567.
    View in: PubMed
  34. Bichara DA, Bodugoz-Sentruk H, Ling D, Malchau E, Bragdon CR, Muratoglu OK. Osteochondral defect repair using a polyvinyl alcohol-polyacrylic acid (PVA-PAAc) hydrogel. Biomed Mater. 2014 Aug; 9(4):045012. PMID: 25050611.
    View in: PubMed
  35. Beecher B, Huddleston J, Rowell S, Goodman S, Malchau H, Kwon YM, Muratoglu OK. Material Properties of a Highly Anteverted Vitamin E-Stabilized Polyethylene Liner After Sixteen Months In Vivo: A Case Report. JBJS Case Connect. 2014 Jul 09; 4(3):e57-e5. PMID: 29252526.
    View in: PubMed
  36. Bichara DA, Malchau E, Sillesen NH, Cakmak S, Nielsen GP, Muratoglu OK. Vitamin E-diffused highly cross-linked UHMWPE particles induce less osteolysis compared to highly cross-linked virgin UHMWPE particles in vivo. J Arthroplasty. 2014 Sep; 29(9 Suppl):232-7. PMID: 24998319.
    View in: PubMed
  37. Oral E, Neils A, Yabannavar P, Muratoglu OK. The effect of an additional phosphite stabilizer on the properties of radiation cross-linked vitamin E blends of UHMWPE. J Orthop Res. 2014 Jun; 32(6):757-61. PMID: 24536024.
    View in: PubMed
  38. Oral E, Neils AL, Rowell SL, Lozynsky AJ, Muratoglu OK. Increasing irradiation temperature maximizes vitamin E grafting and wear resistance of ultrahigh molecular weight polyethylene. J Biomed Mater Res B Appl Biomater. 2013 Apr; 101(3):436-40. PMID: 23115033.
    View in: PubMed
  39. Oral E, Neils AL, Lyons C, Fung M, Doshi B, Muratoglu OK. Surface cross-linked UHMWPE can enable the use of larger femoral heads in total joints. J Orthop Res. 2013 Jan; 31(1):59-66. PMID: 22847503.
    View in: PubMed
  40. Oral E, Ghali BW, Neils A, Muratoglu OK. A new mechanism of oxidation in ultrahigh molecular weight polyethylene caused by squalene absorption. J Biomed Mater Res B Appl Biomater. 2012 Apr; 100(3):742-51. PMID: 22190411.
    View in: PubMed
  41. Choi J, Kung HJ, Macias CE, Muratoglu OK. Highly lubricious poly(vinyl alcohol)-poly(acrylic acid) hydrogels. J Biomed Mater Res B Appl Biomater. 2012 Feb; 100(2):524-32. PMID: 22120954.
    View in: PubMed
  42. Micheli BR, Wannomae KK, Lozynsky AJ, Christensen SD, Muratoglu OK. Knee simulator wear of vitamin E stabilized irradiated ultrahigh molecular weight polyethylene. J Arthroplasty. 2012 Jan; 27(1):95-104. PMID: 21550762.
    View in: PubMed
  43. Oral E, Ghali BW, Muratoglu OK. The elimination of free radicals in irradiated UHMWPEs with and without vitamin E stabilization by annealing under pressure. J Biomed Mater Res B Appl Biomater. 2011 Apr; 97(1):167-74. PMID: 21381192; PMCID: PMC3747829.
  44. Rowell SL, Oral E, Muratoglu OK. Comparative oxidative stability of a-tocopherol blended and diffused UHMWPEs at 3 years of real-time aging. J Orthop Res. 2011 May; 29(5):773-80. PMID: 21437958.
    View in: PubMed
  45. Oral E, Muratoglu OK. Vitamin E diffused, highly crosslinked UHMWPE: a review. Int Orthop. 2011 Feb; 35(2):215-23. PMID: 21120476; PMCID: PMC3032101.
  46. Muratoglu OK, Wannomae KK, Rowell SL, Micheli BR, Malchau H. Ex vivo stability loss of irradiated and melted ultra-high molecular weight polyethylene. J Bone Joint Surg Am. 2010 Dec 01; 92(17):2809-16. PMID: 21123611.
    View in: PubMed
  47. Jarrett BT, Cofske J, Rosenberg AE, Oral E, Muratoglu O, Malchau H. In vivo biological response to vitamin E and vitamin-E-doped polyethylene. J Bone Joint Surg Am. 2010 Nov 17; 92(16):2672-81. PMID: 21084577.
    View in: PubMed
  48. Bichara DA, Zhao X, Bodugoz-Senturk H, Ballyns FP, Oral E, Randolph MA, Bonassar LJ, Gill TJ, Muratoglu OK. Porous poly(vinyl alcohol)-hydrogel matrix-engineered biosynthetic cartilage. Tissue Eng Part A. 2011 Feb; 17(3-4):301-9. PMID: 20799889.
    View in: PubMed
  49. Malchau H, Bragdon CR, Muratoglu OK. The stepwise introduction of innovation into orthopedic surgery: the next level of dilemmas. J Arthroplasty. 2011 Sep; 26(6):825-31. PMID: 20888183.
    View in: PubMed
  50. Solis J, Levine RA, Johnson B, Guerrero JL, Handschumacher MD, Sullivan S, Lam K, Berlin J, Braithwaite GJ, Muratoglu OK, Vlahakes GJ, Hung J. Polymer injection therapy to reverse remodel the papillary muscles: efficacy in reducing mitral regurgitation in a chronic ischemic model. Circ Cardiovasc Interv. 2010 Oct; 3(5):499-505. PMID: 20736444; PMCID: PMC2972670.
  51. Oral E, Ghali BW, Rowell SL, Micheli BR, Lozynsky AJ, Muratoglu OK. A surface crosslinked UHMWPE stabilized by vitamin E with low wear and high fatigue strength. Biomaterials. 2010 Sep; 31(27):7051-60. PMID: 20579730.
    View in: PubMed
  52. Bichara DA, Zhao X, Hwang NS, Bodugoz-Senturk H, Yaremchuk MJ, Randolph MA, Muratoglu OK. Porous poly(vinyl alcohol)-alginate gel hybrid construct for neocartilage formation using human nasoseptal cells. J Surg Res. 2010 Oct; 163(2):331-6. PMID: 20538292.
    View in: PubMed
  53. Oral E, Godleski-Beckos C, Ghali BW, Lozynsky AJ, Muratoglu OK. Effect of cross-link density on the high pressure crystallization of UHMWPE. J Biomed Mater Res B Appl Biomater. 2009 Aug; 90(2):720-9. PMID: 19213055; PMCID: PMC3065948.
  54. Wannomae KK, Christensen SD, Micheli BR, Rowell SL, Schroeder DW, Muratoglu OK. Delamination and adhesive wear behavior of alpha-tocopherol-stabilized irradiated ultrahigh-molecular-weight polyethylene. J Arthroplasty. 2010 Jun; 25(4):635-43. PMID: 19493652.
    View in: PubMed
  55. Oral E, Godleski Beckos CA, Lozynsky AJ, Malhi AS, Muratoglu OK. Improved resistance to wear and fatigue fracture in high pressure crystallized vitamin E-containing ultra-high molecular weight polyethylene. Biomaterials. 2009 Apr; 30(10):1870-80. PMID: 19135247; PMCID: PMC3747844.
  56. Duffy GP, Wannomae KK, Rowell SL, Muratoglu OK. Fracture of a cross-linked polyethylene liner due to impingement. J Arthroplasty. 2009 Jan; 24(1):158.e15-9. PMID: 19100926.
    View in: PubMed
  57. Bodugoz-Senturk H, Macias CE, Kung JH, Muratoglu OK. Poly(vinyl alcohol)-acrylamide hydrogels as load-bearing cartilage substitute. Biomaterials. 2009 Feb; 30(4):589-96. PMID: 18996584.
    View in: PubMed
  58. Oral E, Beckos CG, Muratoglu OK. FREE RADICAL ELIMINATION IN IRRADIATED UHMWPE THROUGH CRYSTAL MOBILITY IN PHASE TRANSITION TO THE HEXAGONAL PHASE. Polymer (Guildf). 2008 Oct 06; 49(21):4733-4739. PMID: 18985170.
    View in: PubMed
  59. Hung J, Solis J, Guerrero JL, Braithwaite GJ, Muratoglu OK, Chaput M, Fernandez-Friera L, Handschumacher MD, Wedeen VJ, Houser S, Vlahakes GJ, Levine RA. A novel approach for reducing ischemic mitral regurgitation by injection of a polymer to reverse remodel and reposition displaced papillary muscles. Circulation. 2008 Sep 30; 118(14 Suppl):S263-9. PMID: 18824765; PMCID: PMC2981105.
  60. Oral E, Malhi AS, Wannomae KK, Muratoglu OK. Highly cross-linked ultrahigh molecular weight polyethylene with improved fatigue resistance for total joint arthroplasty: recipient of the 2006 Hap Paul Award. J Arthroplasty. 2008 Oct; 23(7):1037-44. PMID: 18547783; PMCID: PMC2614333.
  61. Oral E, Godleski Beckos C, Malhi AS, Muratoglu OK. The effects of high dose irradiation on the cross-linking of vitamin E-blended ultrahigh molecular weight polyethylene. Biomaterials. 2008 Sep; 29(26):3557-60. PMID: 18514813; PMCID: PMC2516939.
  62. Crowninshield RD, Muratoglu OK. How have new sterilization techniques and new forms of polyethylene influenced wear in total joint replacement? J Am Acad Orthop Surg. 2008; 16 Suppl 1:S80-5. PMID: 18612021.
    View in: PubMed
  63. Oral E, Muratoglu OK. Radiation cross-linking in ultra-high molecular weight polyethylene for orthopaedic applications. Nucl Instrum Methods Phys Res B. 2007 Dec; 265(1):18-22. PMID: 19050735.
    View in: PubMed
  64. Bodugoz-Senturk H, Choi J, Oral E, Kung JH, Macias CE, Braithwaite G, Muratoglu OK. The effect of polyethylene glycol on the stability of pores in polyvinyl alcohol hydrogels during annealing. Biomaterials. 2008 Jan; 29(2):141-9. PMID: 17950839.
    View in: PubMed
  65. Oral E, Wannomae KK, Rowell SL, Muratoglu OK. Diffusion of vitamin E in ultra-high molecular weight polyethylene. Biomaterials. 2007 Dec; 28(35):5225-37. PMID: 17881049; PMCID: PMC2094214.
  66. Estok DM, Burroughs BR, Muratoglu OK, Harris WH. Comparison of hip simulator wear of 2 different highly cross-linked ultra high molecular weight polyethylene acetabular components using both 32- and 38-mm femoral heads. J Arthroplasty. 2007 Jun; 22(4):581-9. PMID: 17562417.
    View in: PubMed
  67. Muratoglu OK, Rubash HE, Bragdon CR, Burroughs BR, Huang A, Harris WH. Simulated normal gait wear testing of a highly cross-linked polyethylene tibial insert. J Arthroplasty. 2007 Apr; 22(3):435-44. PMID: 17400100.
    View in: PubMed
  68. Plank GR, Estok DM, Muratoglu OK, O'Connor DO, Burroughs BR, Harris WH. Contact stress assessment of conventional and highly crosslinked ultra high molecular weight polyethylene acetabular liners with finite element analysis and pressure sensitive film. J Biomed Mater Res B Appl Biomater. 2007 Jan; 80(1):1-10. PMID: 16680685.
    View in: PubMed
  69. Burroughs BR, Rubash HE, Estok D, Jasty M, Krevolin J, Muratoglu OK. Comparison of conventional and highly crosslinked UHMWPE patellae evaluated by a new in vitro patellofemoral joint simulator. J Biomed Mater Res B Appl Biomater. 2006 Nov; 79(2):268-74. PMID: 16637026.
    View in: PubMed
  70. Choi J, Bodugoz-Senturk H, Kung HJ, Malhi AS, Muratoglu OK. Effects of solvent dehydration on creep resistance of poly(vinyl alcohol) hydrogel. Biomaterials. 2007 Feb; 28(5):772-80. PMID: 17070904.
    View in: PubMed
  71. Burroughs BR, Muratoglu OK, Bragdon CR, Wannomae KK, Christensen S, Lozynsky AJ, Harris WH. In vitro comparison of frictional torque and torsional resistance of aged conventional gamma-in-nitrogen sterilized polyethylene versus aged highly crosslinked polyethylene articulating against head sizes larger than 32 mm. Acta Orthop. 2006 Oct; 77(5):710-8. PMID: 17068700.
    View in: PubMed
  72. Oral E, Rowell SL, Muratoglu OK. The effect of alpha-tocopherol on the oxidation and free radical decay in irradiated UHMWPE. Biomaterials. 2006 Nov; 27(32):5580-7. PMID: 16887182; PMCID: PMC2570163.
  73. Wannomae KK, Bhattacharyya S, Freiberg A, Estok D, Harris WH, Muratoglu O. In vivo oxidation of retrieved cross-linked ultra-high-molecular-weight polyethylene acetabular components with residual free radicals. J Arthroplasty. 2006 Oct; 21(7):1005-11. PMID: 17027543.
    View in: PubMed
  74. Oral E, Christensen SD, Malhi AS, Wannomae KK, Muratoglu OK. Wear resistance and mechanical properties of highly cross-linked, ultrahigh-molecular weight polyethylene doped with vitamin E. J Arthroplasty. 2006 Jun; 21(4):580-91. PMID: 16781413; PMCID: PMC2716092.
  75. Oral E, Wannomae KK, Rowell SL, Muratoglu OK. Migration stability of alpha-tocopherol in irradiated UHMWPE. Biomaterials. 2006 Apr; 27(11):2434-9. PMID: 16325903; PMCID: PMC2576299.
  76. Wannomae KK, Christensen SD, Freiberg AA, Bhattacharyya S, Harris WH, Muratoglu OK. The effect of real-time aging on the oxidation and wear of highly cross-linked UHMWPE acetabular liners. Biomaterials. 2006 Mar; 27(9):1980-7. PMID: 16271756.
    View in: PubMed
  77. Oral E, Greenbaum ES, Malhi AS, Harris WH, Muratoglu OK. Characterization of irradiated blends of alpha-tocopherol and UHMWPE. Biomaterials. 2005 Nov; 26(33):6657-63. PMID: 15993487; PMCID: PMC1463566.
  78. Pavoor PV, Gearing BP, Muratoglu O, Cohen RE, Bellare A. Wear reduction of orthopaedic bearing surfaces using polyelectrolyte multilayer nanocoatings. Biomaterials. 2006 Mar; 27(8):1527-33. PMID: 16174529.
    View in: PubMed
  79. Muratoglu OK, Wannomae K, Christensen S, Rubash HE, Harris WH. Ex vivo wear of conventional and cross-linked polyethylene acetabular liners. Clin Orthop Relat Res. 2005 Sep; 438:158-64. PMID: 16131885.
    View in: PubMed
  80. Oral E, Malhi AS, Muratoglu OK. Mechanisms of decrease in fatigue crack propagation resistance in irradiated and melted UHMWPE. Biomaterials. 2006 Feb; 27(6):917-25. PMID: 16105682; PMCID: PMC1463251.
  81. Jasty M, Rubash HE, Muratoglu O. Highly cross-linked polyethylene: the debate is over--in the affirmative. J Arthroplasty. 2005 Jun; 20(4 Suppl 2):55-8. PMID: 15991131.
    View in: PubMed
  82. Bragdon CR, Jasty M, Muratoglu OK, Harris WH. Third-body wear testing of a highly cross-linked acetabular liner: the effect of large femoral head size in the presence of particulate poly(methyl-methacrylate) debris. J Arthroplasty. 2005 Apr; 20(3):379-85. PMID: 15809958.
    View in: PubMed
  83. Muratoglu OK, Spiegelberg SH, McKinley GH. A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt. 2005.
  84. Estok DM, Bragdon CR, Plank GR, Huang A, Muratoglu OK, Harris WH. The measurement of creep in ultrahigh molecular weight polyethylene: a comparison of conventional versus highly cross-linked polyethylene. J Arthroplasty. 2005 Feb; 20(2):239-43. PMID: 15902864.
    View in: PubMed
  85. Harris WH, Muratoglu OK. A review of current cross-linked polyethylenes used in total joint arthroplasty. Clin Orthop Relat Res. 2005 Jan; (430):46-52. PMID: 15662303.
    View in: PubMed
  86. Wannomae KK, Bhattacharyya S, Freiberg AA, Estok D, Harris WH, Muratoglu OK. In vivo oxidation of retrieved crosslinked UHMWPE acetabular components with residual free radicals. Journal of Arthroplasty. 2005; in print.
  87. Merrill EW, Harris WH, Jasty M, Muratoglu OK, Bragdon CR, O’Connor DO, Venugopalan, P. Radiation and Melt Treated Ultra High Molecular Weight Polyethylene Prosthetic Devices. 2004.
  88. Muratoglu OK, Burroughs BR, Bragdon CR, Christensen S, Lozynsky A, Harris WH. Knee simulator wear of polyethylene tibias articulating against explanted rough femoral components. Clin Orthop Relat Res. 2004 Nov; (428):108-13. PMID: 15534529.
    View in: PubMed
  89. Oral E, Wannomae KK, Hawkins N, Harris WH, Muratoglu OK. Alpha-tocopherol-doped irradiated UHMWPE for high fatigue resistance and low wear. Biomaterials. 2004 Nov; 25(24):5515-22. PMID: 15142733.
    View in: PubMed
  90. Muratoglu OK, Bragdon CR, Jasty M, O'Connor DO, Von Knoch RS, Harris WH. Knee-simulator testing of conventional and cross-linked polyethylene tibial inserts. J Arthroplasty. 2004 Oct; 19(7):887-97. PMID: 15483806.
    View in: PubMed
  91. Merrill EW, Harris WH, Jasty M, Muratoglu OK, Bragdon CR, O’Connor DO, Venugopalan, P. Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices. 2004.
  92. Greenbaum ES, Burroughs BB, Harris WH, Muratoglu OK. Effect of lipid absorption on wear and compressive properties of unirradiated and highly crosslinked UHMWPE: an in vitro experimental model. Biomaterials. 2004 Aug; 25(18):4479-84. PMID: 15046938.
    View in: PubMed
  93. Muratoglu OK, Greenbaum ES, Bragdon CR, Jasty M, Freiberg AA, Harris WH. Surface analysis of early retrieved acetabular polyethylene liners: a comparison of conventional and highly crosslinked polyethylenes. J Arthroplasty. 2004 Jan; 19(1):68-77. PMID: 14716654.
    View in: PubMed
  94. Muratoglu OK. In vitro wear of acetabular liners. Callaghan JJ, Rosenberg AG, Rubash HE. The Adult Hip. 2004; in print.
  95. Muratoglu OK, Burroughs BR, Bragdon CR, Christensen S, Lozynsky A, Harris WH. Knee Simulator Wear of Polyethylene Tibias Articulating Against Explanted Rough Femoral Components. Clin Orthop. 2004; 428:108-113.
  96. Crowninshield RD, Muratoglu OK, Hawkins M. Polyethylene in total hip replacement. Callaghan JJ, Rosenberg AG, Rubash HE. The Adult Hip. 2004; (in print):in print.
  97. Muratoglu OK. Polyethylene basic science and general knowledge. Orthopaedic knowledge update: Hip and knee reconstruction. 2004.
  98. Harris WH, Muratoglu OK. A Review of Current Cross-linked Polyethylenes Used in Total Joint Arthroplasty. Clin Orthop. 2004; in print.
  99. Harris WH, Jasty M, Muratoglu OK, O'Connor D, Bragdon C. Polyethylene hip joint prosthesis with extended range of motion. 2004.
  100. Muratoglu OK, Merrill EW, Bragdon CR, O'Connor D, Hoeffel D, Burroughs B, Jasty M, Harris WH. Effect of radiation, heat, and aging on in vitro wear resistance of polyethylene. Clin Orthop Relat Res. 2003 Dec; (417):253-62. PMID: 14646724.
    View in: PubMed
  101. Muratoglu OK, Ruberti J, Melotti S, Spiegelberg SH, Greenbaum ES, Harris WH. Optical analysis of surface changes on early retrievals of highly cross-linked and conventional polyethylene tibial inserts. J Arthroplasty. 2003 Oct; 18(7 Suppl 1):42-7. PMID: 14560410.
    View in: PubMed
  102. Bragdon CR, Jasty M, Muratoglu OK, O'Connor DO, Harris WH. Third-body wear of highly cross-linked polyethylene in a hip simulator. J Arthroplasty. 2003 Aug; 18(5):553-61. PMID: 12934205.
    View in: PubMed
  103. Santavirta S, Böhler M, Harris WH, Konttinen YT, Lappalainen R, Muratoglu O, Rieker C, Salzer M. Alternative materials to improve total hip replacement tribology. Acta Orthop Scand. 2003 Aug; 74(4):380-8. PMID: 14521286.
    View in: PubMed
  104. Gul RM, McGarry FJ, Bragdon CR, Muratoglu OK, Harris WH. Effect of consolidation on adhesive and abrasive wear of ultra high molecular weight polyethylene. Biomaterials. 2003 Aug; 24(19):3193-9. PMID: 12763446.
    View in: PubMed
  105. Muratoglu OK, Delaney J, O'Connor DO, Harris WH. The use of trans-vinylene formation in quantifying the spatial distribution of electron beam penetration in polyethylene. Single-sided, double-sided and shielded irradiation. Biomaterials. 2003 May; 24(12):2021-9. PMID: 12628821.
    View in: PubMed
  106. Muratoglu OK, Perinchief RS, Bragdon CR, O'Connor DO, Konrad R, Harris WH. Metrology to quantify wear and creep of polyethylene tibial knee inserts. Clin Orthop Relat Res. 2003 May; (410):155-64. PMID: 12771826.
    View in: PubMed
  107. Merrill EW, Harris WH, Muratoglu OK, O’Connor DO, Venugopalan P, Bragdon CR, Jasty M. Radiation and melt treated UHMWPE prosthetic devices. 2003.
  108. Merrill EW, Harris WH, Jasty M, Muratoglu OK, Bragdon CR, O’Connor DO, Venugopalan, P. Radiation and melt treated ultra high molecular weight polyethylene prosthetic device and method. 2003.
  109. Muratoglu OK, Mark A, Vittetoe DA, Harris WH, Rubash HE. Polyethylene damage in total knees and use of highly crosslinked polyethylene. J Bone Joint Surg Am. 2003; 85-A Suppl 1:S7-S13. PMID: 12540663.
    View in: PubMed
  110. Muratoglu OK, Vittetoe DA, Rubash HE. Damage of Implant Surfaces in Total Knee Arthroplasty. Callaghan JJ, Rosenberg AG, Rubash HE, Simonian PT, Wickiewicz TJ. The Adult Knee. 2003; in print:297-313.
  111. Santavirta S, Bohler M, Harris WH, Konttinen YT, Lapalainen R, Muratoglu OK, Rieker C, Salzer M. Alternative Materials to Improve Total Hip Replacement Tribology. Acta Scandinavia. 2003; 380-386.
  112. Burroughs BR, Muratoglu OK, Rubash HE, Estok D, Jasty M, Freiberg AF, Harris WH. Development of a New In Vitro Patella Wear Tester in the Orthopaedic Biomechanics and Biomaterials Laboratory. The Orthopaedic Journal at Harvard Medical School. 2003; 102-103.
  113. Muratoglu OK, Bragdon CR, O'Connor DO, Perinchief RS, Jasty M, Harris WH. Aggressive wear testing of a cross-linked polyethylene in total knee arthroplasty. Clin Orthop Relat Res. 2002 Nov; (404):89-95. PMID: 12439243.
    View in: PubMed
  114. Muratoglu OK, O'Connor DO, Bragdon CR, Delaney J, Jasty M, Harris WH, Merrill E, Venugopalan P. Gradient crosslinking of UHMWPE using irradiation in molten state for total joint arthroplasty. Biomaterials. 2002 Feb; 23(3):717-24. PMID: 11771692.
    View in: PubMed
  115. Muratoglu OK, Harris WH. Use of highly crossliked UHMWPE in THR to decrease the generation of wear debris and reduce periprostheic osteolysis. Illgen R, Rubash HE. Seminars in Arthroplasty. 2002; 13(4):318-324.
  116. Muratoglu OK, Harris WH. Electron Beam Crosslinked and Melted Polyethylene in Total Hip and Knee Arthroplasty. Shanhbag AS, Rubash HE, Jacobs JJ. Joint Replacement and Bone Resorption: Pathology, Biomaterials, and Clinical Practice. 2002.
  117. Muratoglu OK, Deluzio K, Rubash HE, Harris WH. The use of high dose irradiated and melt treated UHMWPE in TKR to decrease the incidence of delamination and wear debris generation. Illgen R, Rubash HE. Seminars in Arthroplasty. 2002; 13(4):338-342.
  118. Muratoglu OK, Mark AK, Harris WH, Rubash HE. Electron Beam Crosslinked and Melted Polyethylene Should be Used in Total Knee Replacements. AAOS Bulletin. 2002; 50-51.
  119. Kurtz SM, Muratoglu OK, Gsell R, Greer K, Shen FW, Cooper C, Buchanan FJ, Spiegelberg S, Yau SS, Edidin AA. Interlaboratory validation of oxidation-index measurement methods for UHMWPE after long-term shelf aging. J Biomed Mater Res. 2002; 63(1):15-23. PMID: 11787024.
    View in: PubMed
  120. Konrad R, Rieker C, Schon R, Muratoglu OK, Perinchief R. A New Measurement Method for Wear Scars Generated with Knee Simulators. Hutchings IM. Friction, Lubrication, and Wear of Artificial Joints. 2002; 127-132.
  121. Muratoglu OK, Kurtz SM. Alternate bearings in hip replacement. Sinha RK. Total Hip Replacement: Current Trends and Controversies. 2002; 1-46.
  122. Muratoglu OK, Bragdon CR, O'Connor D, Perinchief RS, Estok DM, Jasty M, Harris WH. Larger diameter femoral heads used in conjunction with a highly cross-linked ultra-high molecular weight polyethylene: a new concept. J Arthroplasty. 2001 Dec; 16(8 Suppl 1):24-30. PMID: 11742447.
    View in: PubMed
  123. Duffy GP, Muratoglu OK, Biggs SA, Larson SL, Lozynsky AJ, Harris WH. A critical assessment of proximal macrotexturing on cemented femoral components. J Arthroplasty. 2001 Dec; 16(8 Suppl 1):42-8. PMID: 11742450.
    View in: PubMed
  124. Kurt SM, Muratoglu OK, Buchanan FJ, Currier B, Gsell R, Shen FW, Yau SS. Interlaboratory studies to determine optimal analytical methods for measuring the oxidation index of UHMWPE. Biomaterials. 2001 Nov; 22(21):2875-81. PMID: 11561893.
    View in: PubMed
  125. Muratoglu OK. The comparison of the wear behavior of four different types of crosslinked acetabular components. J Orthop Res. 2001 Nov; 19(6):1210. PMID: 11781026.
    View in: PubMed
  126. Muratoglu OK, Harris WH. Identification and quantification of irradiation in UHMWPE through trans-vinylene yield. J Biomed Mater Res. 2001 Sep 15; 56(4):584-92. PMID: 11400137.
    View in: PubMed
  127. Kurtz SM, Muratoglu OK, Buchanan F, Currier B, Gsell R, Greer K, Gualtieri G, Johnson R, Schaffner S, Sevo K, Spiegelberg S, Shen FW, Yau SS. Interlaboratory reproducibility of standard accelerated aging methods for oxidation of UHMWPE. Biomaterials. 2001 Jul; 22(13):1731-7. PMID: 11396876.
    View in: PubMed
  128. Muratoglu OK, Bragdon CR, O'Connor DO, Jasty M, Harris WH. A novel method of cross-linking ultra-high-molecular-weight polyethylene to improve wear, reduce oxidation, and retain mechanical properties. Recipient of the 1999 HAP Paul Award. J Arthroplasty. 2001 Feb; 16(2):149-60. PMID: 11222887.
    View in: PubMed
  129. Muratoglu OK. Implant wear in total joint replacement: Clinical and biological issues, materials and design considerations. 2001; 193-203.
  130. Merrill EW, Harris WH, Muratoglu OK, O’Connor DO, Venugopalan P, Bragdon CR, Jasty M. Radiation and melt treated UHMWPE prosthetic devices. 2001.
  131. Muratoglu OK, Bragdon CR, O'Connor DO, Jasty M, Harris WH. A highly crosslinked, melted ultra-high molecular weight polyethylene: Expanded potential for total joint arthroplasty. Reiker C, Oberhaulzer S, Wyss U, Huber H. World Tribology Forum in Arthroplasty. 2001; 245-262.
  132. Argon AS, Bartczak Z, Cohen RE, Muratoglu OK. Novel mechanism of toughening semi-crystalline polymers. Pearson RA, Sue H-J, Yee, AF. ACS Symposium Series 759. 2000; 98-124.
  133. Merrill EW, Harris WH, Muratoglu OK, O’Connor DO, Venugopalan P, Bragdon CR, Jasty M. Radiation and melt treated UHMWPE prosthetic devices. 2000.
  134. Kurtz SM, Muratoglu OK, Evans M, Edidin AA. Advances in the processing, sterilization, and crosslinking of ultra-high molecular weight polyethylene for total joint arthroplasty. Biomaterials. 1999 Sep; 20(18):1659-88. PMID: 10503968.
    View in: PubMed
  135. Muratoglu OK, Bragdon CR, O'Connor DO, Jasty M, Harris WH, Gul R, McGarry F. Unified wear model for highly crosslinked ultra-high molecular weight polyethylenes (UHMWPE). Biomaterials. 1999 Aug; 20(16):1463-70. PMID: 10458559.
    View in: PubMed
  136. Muratoglu OK, Jasty M, Harris WH. A new method to determine the locus of radiation damage in retrieved UHMWPE components. ASTM-SMP. 1997; (1307):79.
  137. Argon AS, Bartczak Z, Cohen RE, Muratoglu OK. Novel mechanisms of toughening semi-crystalline polymers. Proc. 18th Riso International Symposium on Materials Science: Polymeric Composites-Expanding the Limits, Eds: Andersen SI, Brondted P, Lillhot H, Lystrup A, Rheinlander JT, Sorensen BF, Toftegaard H. 1997.
  138. Muratoglu OK, Cohen RE, Argon AS, Weinberg M. Microstructural processes of fracture of rubber modified polyamides. Polymer. 1995; 36(25):4771.
  139. Muratoglu OK, Cohen RE, Argon AS, Weinberg M. Microstructural Fracture Processes Accompanying Growing Cracks in Tough Rubber-Modified Polyamides. Polymer. 1995; 36(25):4787.
  140. Muratoglu OK, Cohen RE, Argon AS, Weinberg M. Toughening mechanism of rubber modified polyamides. Polymer. 1995; 36(5):921.
  141. Argon AS, Cohen RE, Muratoglu OK. Toughness of particle modified sem-crystalline polymers: General principles and specific examples. Boyce MC. Mechanics of plastics and plastic composites. 1995; 177-195.
  142. Muratoglu OK, Cohen RE, Argon AS. Crystalline morphology of polyamide 6 near planar surfaces. Polymer. 1995; 36(11):2143.
  143. Muratoglu, OK. Microstructural processes governing the fracture and toughening mechanisms of rubber modified polyamides: A morphological approach. 1995.
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