Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Zak Kohane, M.D.,Ph.D.

Co-Author

This page shows the publications co-authored by Zak Kohane and Shawn Murphy.
Connection Strength

7.110
  1. Combining clinical and genomics queries using i2b2 - Three methods. PLoS One. 2017; 12(4):e0172187.
    View in: PubMed
    Score: 0.724
  2. A translational engine at the national scale: informatics for integrating biology and the bedside. J Am Med Inform Assoc. 2012 Mar-Apr; 19(2):181-5.
    View in: PubMed
    Score: 0.497
  3. Strategies for maintaining patient privacy in i2b2. J Am Med Inform Assoc. 2011 Dec; 18 Suppl 1:i103-8.
    View in: PubMed
    Score: 0.494
  4. Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2). J Am Med Inform Assoc. 2010 Mar-Apr; 17(2):124-30.
    View in: PubMed
    Score: 0.442
  5. Instrumenting the health care enterprise for discovery research in the genomic era. Genome Res. 2009 Sep; 19(9):1675-81.
    View in: PubMed
    Score: 0.423
  6. Validation of an internationally derived patient severity phenotype to support COVID-19 analytics from electronic health record data. J Am Med Inform Assoc. 2021 07 14; 28(7):1411-1420.
    View in: PubMed
    Score: 0.243
  7. What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask. J Med Internet Res. 2021 03 02; 23(3):e22219.
    View in: PubMed
    Score: 0.237
  8. International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium. NPJ Digit Med. 2020; 3:109.
    View in: PubMed
    Score: 0.228
  9. Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis. Inflamm Bowel Dis. 2016 Apr; 22(4):880-5.
    View in: PubMed
    Score: 0.169
  10. Statin Use Is Associated With Reduced Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2016 07; 14(7):973-9.
    View in: PubMed
    Score: 0.167
  11. Development of phenotype algorithms using electronic medical records and incorporating natural language processing. BMJ. 2015 Apr 24; 350:h1885.
    View in: PubMed
    Score: 0.158
  12. Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS): architecture. J Am Med Inform Assoc. 2014 Jul-Aug; 21(4):615-20.
    View in: PubMed
    Score: 0.148
  13. SHRINE: enabling nationally scalable multi-site disease studies. PLoS One. 2013; 8(3):e55811.
    View in: PubMed
    Score: 0.136
  14. Apps to display patient data, making SMART available in the i2b2 platform. AMIA Annu Symp Proc. 2012; 2012:960-9.
    View in: PubMed
    Score: 0.133
  15. The co-morbidity burden of children and young adults with autism spectrum disorders. PLoS One. 2012; 7(4):e33224.
    View in: PubMed
    Score: 0.128
  16. The SMART Platform: early experience enabling substitutable applications for electronic health records. J Am Med Inform Assoc. 2012 Jul-Aug; 19(4):597-603.
    View in: PubMed
    Score: 0.127
  17. Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2012 Apr; 35(7):789-95.
    View in: PubMed
    Score: 0.127
  18. Rapid identification of myocardial infarction risk associated with diabetes medications using electronic medical records. Diabetes Care. 2010 Mar; 33(3):526-31.
    View in: PubMed
    Score: 0.109
  19. The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories. J Am Med Inform Assoc. 2009 Sep-Oct; 16(5):624-30.
    View in: PubMed
    Score: 0.106
  20. Integrating outside modules into the i2b2 architecture. AMIA Annu Symp Proc. 2008 Nov 06; 1054.
    View in: PubMed
    Score: 0.101
  21. Architecture of the open-source clinical research chart from Informatics for Integrating Biology and the Bedside. AMIA Annu Symp Proc. 2007 Oct 11; 548-52.
    View in: PubMed
    Score: 0.094
  22. Mapping tool for maintaining vocabulary relationships. AMIA Annu Symp Proc. 2006; 939.
    View in: PubMed
    Score: 0.083
  23. Integration of clinical and genetic data in the i2b2 architecture. AMIA Annu Symp Proc. 2006; 1040.
    View in: PubMed
    Score: 0.083
  24. International Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: Retrospective Cohort Study. J Med Internet Res. 2021 10 11; 23(10):e31400.
    View in: PubMed
    Score: 0.062
  25. ATLAS: an automated association test using probabilistically linked health records with application to genetic studies. J Am Med Inform Assoc. 2021 Oct 05.
    View in: PubMed
    Score: 0.062
  26. International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries. JAMA Netw Open. 2021 06 01; 4(6):e2112596.
    View in: PubMed
    Score: 0.060
  27. International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort Study. medRxiv. 2021 Feb 05.
    View in: PubMed
    Score: 0.059
  28. High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP). Nat Protoc. 2019 12; 14(12):3426-3444.
    View in: PubMed
    Score: 0.054
  29. High-throughput multimodal automated phenotyping (MAP) with application to PheWAS. J Am Med Inform Assoc. 2019 11 01; 26(11):1255-1262.
    View in: PubMed
    Score: 0.054
  30. Use of Narrative Concepts in Electronic Health Records to Validate Associations Between Genetic Factors and Response to Treatment of Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2020 07; 18(8):1890-1892.
    View in: PubMed
    Score: 0.053
  31. Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes. Sci Data. 2019 01 08; 6:180298.
    View in: PubMed
    Score: 0.051
  32. Enabling phenotypic big data with PheNorm. J Am Med Inform Assoc. 2018 01 01; 25(1):54-60.
    View in: PubMed
    Score: 0.048
  33. Surrogate-assisted feature extraction for high-throughput phenotyping. J Am Med Inform Assoc. 2017 Apr 01; 24(e1):e143-e149.
    View in: PubMed
    Score: 0.045
  34. Sharing electronic medical records across multiple heterogeneous and competing institutions. Proc AMIA Annu Fall Symp. 1996; 608-12.
    View in: PubMed
    Score: 0.041
  35. Using HL7 and the World Wide Web for unifying patient data from remote databases. Proc AMIA Annu Fall Symp. 1996; 643-7.
    View in: PubMed
    Score: 0.041
  36. Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2015 Nov; 21(11):2507-14.
    View in: PubMed
    Score: 0.041
  37. Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts. PLoS One. 2015; 10(8):e0136651.
    View in: PubMed
    Score: 0.040
  38. Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. J Am Med Inform Assoc. 2015 Sep; 22(5):993-1000.
    View in: PubMed
    Score: 0.040
  39. Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases. Aliment Pharmacol Ther. 2015 Jun; 41(11):1141-8.
    View in: PubMed
    Score: 0.039
  40. TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits. PLoS One. 2015; 10(4):e0122271.
    View in: PubMed
    Score: 0.039
  41. Validation of electronic health record phenotyping of bipolar disorder cases and controls. Am J Psychiatry. 2015 Apr; 172(4):363-72.
    View in: PubMed
    Score: 0.039
  42. Stratification of risk for hospital admissions for injury related to fall: cohort study. BMJ. 2014 Oct 24; 349:g5863.
    View in: PubMed
    Score: 0.038
  43. Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Dig Dis Sci. 2015 Feb; 60(2):471-7.
    View in: PubMed
    Score: 0.038
  44. Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system. Mol Psychiatry. 2015 Jun; 20(6):727-34.
    View in: PubMed
    Score: 0.038
  45. An electronic health records study of long-term weight gain following antidepressant use. JAMA Psychiatry. 2014 Aug; 71(8):889-96.
    View in: PubMed
    Score: 0.038
  46. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Hum Genet. 2014 Nov; 133(11):1369-82.
    View in: PubMed
    Score: 0.038
  47. Colonoscopy is associated with a reduced risk for colon cancer and mortality in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2015 Feb; 13(2):322-329.e1.
    View in: PubMed
    Score: 0.037
  48. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Aliment Pharmacol Ther. 2014 May; 39(10):1136-42.
    View in: PubMed
    Score: 0.037
  49. Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Nov; 12(11):1905-10.
    View in: PubMed
    Score: 0.037
  50. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. J Crohns Colitis. 2014 Sep; 8(9):956-63.
    View in: PubMed
    Score: 0.036
  51. Rare copy number variation in treatment-resistant major depressive disorder. Biol Psychiatry. 2014 Oct 01; 76(7):536-41.
    View in: PubMed
    Score: 0.036
  52. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Aug; 12(8):1342-8.e1.
    View in: PubMed
    Score: 0.036
  53. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Arthritis Care Res (Hoboken). 2013 Dec; 65(12):2046-50.
    View in: PubMed
    Score: 0.036
  54. Modeling disease severity in multiple sclerosis using electronic health records. PLoS One. 2013; 8(11):e78927.
    View in: PubMed
    Score: 0.036
  55. Association between reduced plasma 25-hydroxy vitamin D and increased risk of cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 May; 12(5):821-7.
    View in: PubMed
    Score: 0.036
  56. Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease. Inflamm Bowel Dis. 2013 Aug; 19(9):1921-7.
    View in: PubMed
    Score: 0.035
  57. Improving case definition of Crohn's disease and ulcerative colitis in electronic medical records using natural language processing: a novel informatics approach. Inflamm Bowel Dis. 2013 Jun; 19(7):1411-20.
    View in: PubMed
    Score: 0.035
  58. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. Ann Rheum Dis. 2014 Jun; 73(6):1170-5.
    View in: PubMed
    Score: 0.035
  59. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls. Arthritis Rheum. 2013 Mar; 65(3):571-81.
    View in: PubMed
    Score: 0.034
  60. QT interval and antidepressant use: a cross sectional study of electronic health records. BMJ. 2013 Jan 29; 346:f288.
    View in: PubMed
    Score: 0.034
  61. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. Am J Gastroenterol. 2013 Apr; 108(4):594-601.
    View in: PubMed
    Score: 0.034
  62. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease. Aliment Pharmacol Ther. 2013 Feb; 37(4):445-54.
    View in: PubMed
    Score: 0.034
  63. Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: a pilot study. Psychiatry Res. 2013 Mar 30; 211(3):202-13.
    View in: PubMed
    Score: 0.033
  64. Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study. Am J Psychiatry. 2012 Oct; 169(10):1065-72.
    View in: PubMed
    Score: 0.033
  65. Limbic system white matter microstructure and long-term treatment outcome in major depressive disorder: a diffusion tensor imaging study using legacy data. World J Biol Psychiatry. 2014 Feb; 15(2):122-34.
    View in: PubMed
    Score: 0.032
  66. A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry. 2013 Apr; 18(4):497-511.
    View in: PubMed
    Score: 0.032
  67. Incident user cohort study of risk for gastrointestinal bleed and stroke in individuals with major depressive disorder treated with antidepressants. BMJ Open. 2012; 2(2):e000544.
    View in: PubMed
    Score: 0.032
  68. Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model. Psychol Med. 2012 Jan; 42(1):41-50.
    View in: PubMed
    Score: 0.030
  69. Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels. Clin Pharmacol Ther. 2011 Jul; 90(1):133-42.
    View in: PubMed
    Score: 0.030
  70. Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records. Am J Hum Genet. 2011 Jan 07; 88(1):57-69.
    View in: PubMed
    Score: 0.029
  71. Electronic medical records for discovery research in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2010 Aug; 62(8):1120-7.
    View in: PubMed
    Score: 0.028
  72. iTools: a framework for classification, categorization and integration of computational biology resources. PLoS One. 2008 May 28; 3(5):e2265.
    View in: PubMed
    Score: 0.024
  73. Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. J Cell Biol. 2006 Oct 09; 175(1):99-110.
    View in: PubMed
    Score: 0.022
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.