Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Dennis Charles Sgroi, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA112021 (SGROI, DENNIS C) Mar 11, 2005 - Apr 30, 2015
    Role: Principal Investigator
  2. K08AI001252 (SGROI, DENNIS C) Sep 1, 1994 - Aug 31, 1997
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sgroi DC, Treuner K, Zhang Y, Piper T, Salunga R, Ahmed I, Doos L, Thornber S, Taylor KJ, Brachtel E, Pirrie S, Schnabel CA, Rea D, Bartlett JMS. Correlative studies of the Breast Cancer Index (HOXB13/IL17BR) and ER, PR, AR, AR/ER ratio and Ki67 for prediction of extended endocrine therapy benefit: a Trans-aTTom study. Breast Cancer Res. 2022 12 16; 24(1):90. PMID: 36527133; PMCID: PMC9758861.
    Citations: 1     Fields:    Translation:Humans
  2. Bartlett JMS, Sgroi DC, Treuner K, Zhang Y, Piper T, Salunga RC, Ahmed I, Doos L, Thornber S, Taylor KJ, Brachtel EF, Pirrie SJ, Schnabel CA, Rea DW. Breast Cancer Index Is a Predictive Biomarker of Treatment Benefit and Outcome from Extended Tamoxifen Therapy: Final Analysis of the Trans-aTTom Study. Clin Cancer Res. 2022 05 02; 28(9):1871-1880. PMID: 35144966; PMCID: PMC9306281.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  3. Lopez DR, Sgroi D, Krishnamourthy S, Tearney G. Is Real-Time Microscopy on the Horizon? A Brief Review of the Potential Future Directions in Clinical Breast Tumor Microscopy Implementation. Virchows Arch. 2022 Jan; 480(1):211-227. PMID: 35218378.
    Citations:    Fields:    Translation:Humans
  4. Nunes R, Sella T, Treuner K, Atkinson JM, Wong J, Zhang Y, Exman P, Dabbs D, Richardson AL, Schnabel CA, Sgroi DC, Oesterreich S, Cimino-Mathews A, Metzger O. Prognostic Utility of Breast Cancer Index to Stratify Distant Recurrence Risk in Invasive Lobular Carcinoma. Clin Cancer Res. 2021 10 15; 27(20):5688-5696. PMID: 34376532; PMCID: PMC9401569.
    Citations: 1     Fields:    Translation:Humans
  5. Li K, Li T, Feng Z, Huang M, Wei L, Yan Z, Long M, Hu Q, Wang J, Liu S, Sgroi DC, Demehri S. CD8+ T cell immunity blocks the metastasis of carcinogen-exposed breast cancer. Sci Adv. 2021 06; 7(25). PMID: 34144976; PMCID: PMC8213232.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Bartlett JMS, Sgroi DC, Treuner K, Zhang Y, Ahmed I, Piper T, Salunga R, Brachtel EF, Pirrie SJ, Schnabel CA, Rea DW. Breast Cancer Index and prediction of benefit from extended endocrine therapy in breast cancer patients treated in the Adjuvant Tamoxifen-To Offer More? (aTTom) trial. Ann Oncol. 2019 Nov; 30(11):1776-1783. PMID: 31987084.
  7. Bartlett JMS, Sgroi DC, Treuner K, Zhang Y, Ahmed I, Piper T, Salunga R, Brachtel EF, Pirrie SJ, Schnabel CA, Rea DW. Breast Cancer Index and prediction of benefit from extended endocrine therapy in breast cancer patients treated in the Adjuvant Tamoxifen-To Offer More? (aTTom) trial. Ann Oncol. 2019 11 01; 30(11):1776-1783. PMID: 31504126.
    Citations: 25     Fields:    Translation:HumansCTClinical Trials
  8. Drago JZ, Formisano L, Juric D, Niemierko A, Servetto A, Wander SA, Spring LM, Vidula N, Younger J, Peppercorn J, Yuen M, Malvarosa G, Sgroi D, Isakoff SJ, Moy B, Ellisen LW, Iafrate AJ, Arteaga CL, Bardia A. FGFR1 Amplification Mediates Endocrine Resistance but Retains TORC Sensitivity in Metastatic Hormone Receptor-Positive (HR+) Breast Cancer. Clin Cancer Res. 2019 11 01; 25(21):6443-6451. PMID: 31371343; PMCID: PMC6825550.
    Citations: 22     Fields:    Translation:Humans
  9. Yan C, Brunson DC, Tang Q, Do D, Iftimia NA, Moore JC, Hayes MN, Welker AM, Garcia EG, Dubash TD, Hong X, Drapkin BJ, Myers DT, Phat S, Volorio A, Marvin DL, Ligorio M, Dershowitz L, McCarthy KM, Karabacak MN, Fletcher JA, Sgroi DC, Iafrate JA, Maheswaran S, Dyson NJ, Haber DA, Rawls JF, Langenau DM. Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish. Cell. 2019 06 13; 177(7):1903-1914.e14. PMID: 31031007; PMCID: PMC6570580.
    Citations: 89     Fields:    Translation:HumansAnimalsCells
  10. Kabraji S, Sole X, Huang Y, Bango C, Sgroi D, Loda M, Ramaswamy S. AKT1low quiescent cancer cells in ductal carcinoma in situ of the breast. NPJ Breast Cancer. 2019; 5:10. PMID: 30911675; PMCID: PMC6428812.
    Citations: 2     
  11. Jerevall PL, Brock J, Palazzo J, Wieczorek T, Misialek M, Guidi AJ, Wu Y, Erlander MG, Zhang Y, Schnabel CA, Goss PE, Horick N, Sgroi DC. Discrepancy in risk assessment of hormone receptor positive early-stage breast cancer patients using breast cancer index and recurrence score. Breast Cancer Res Treat. 2019 Jan; 173(2):375-383. PMID: 30350269.
    Citations:    Fields:    Translation:Humans
  12. Sestak I, Buus R, Cuzick J, Dubsky P, Kronenwett R, Denkert C, Ferree S, Sgroi D, Schnabel C, Baehner FL, Mallon E, Dowsett M. Comparison of the Performance of 6 Prognostic Signatures for Estrogen Receptor-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial. JAMA Oncol. 2018 Apr 01; 4(4):545-553. PMID: 29450494; PMCID: PMC5885222.
    Citations: 89     Fields:    Translation:HumansCells
  13. Aceto N, Bardia A, Wittner BS, Donaldson MC, O'Keefe R, Engstrom A, Bersani F, Zheng Y, Comaills V, Niederhoffer K, Zhu H, Mackenzie O, Shioda T, Sgroi D, Kapur R, Ting DT, Moy B, Ramaswamy S, Toner M, Haber DA, Maheswaran S. AR Expression in Breast Cancer CTCs Associates with Bone Metastases. Mol Cancer Res. 2018 04; 16(4):720-727. PMID: 29453314; PMCID: PMC5882540.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  14. Matissek KJ, Onozato ML, Sun S, Zheng Z, Schultz A, Lee J, Patel K, Jerevall PL, Saladi SV, Macleay A, Tavallai M, Badovinac-Crnjevic T, Barrios C, Bese N, Chan A, Chavarri-Guerra Y, Debiasi M, Demirdögen E, Egeli Ü, Gökgöz S, Gomez H, Liedke P, Tasdelen I, Tolunay S, Werutsky G, St Louis J, Horick N, Finkelstein DM, Le LP, Bardia A, Goss PE, Sgroi DC, Iafrate AJ, Ellisen LW. Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor-Positive Breast Cancer. Cancer Discov. 2018 03; 8(3):336-353. PMID: 29242214.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  15. Alves CP, Dey-Guha I, Kabraji S, Yeh AC, Talele NP, Solé X, Chowdhury J, Mino-Kenudson M, Loda M, Sgroi D, Borresen-Dale AL, Russnes HG, Ross KN, Ramaswamy S. AKT1low Quiescent Cancer Cells Promote Solid Tumor Growth. Mol Cancer Ther. 2018 01; 17(1):254-263. PMID: 29054988; PMCID: PMC5752592.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  16. Zhang Y, Schroeder BE, Jerevall PL, Ly A, Nolan H, Schnabel CA, Sgroi DC. A Novel Breast Cancer Index for Prediction of Distant Recurrence in HR+ Early-Stage Breast Cancer with One to Three Positive Nodes. Clin Cancer Res. 2017 Dec 01; 23(23):7217-7224. PMID: 28939745.
    Citations: 7     Fields:    Translation:Humans
  17. Schroeder B, Zhang Y, Stål O, Fornander T, Brufsky A, Sgroi DC, Schnabel CA. Risk stratification with Breast Cancer Index for late distant recurrence in patients with clinically low-risk (T1N0) estrogen receptor-positive breast cancer. NPJ Breast Cancer. 2017; 3:28. PMID: 28795152; PMCID: PMC5543049.
    Citations: 2     
  18. Kabraji S, Solé X, Huang Y, Bango C, Bowden M, Bardia A, Sgroi D, Loda M, Ramaswamy S. AKT1low quiescent cancer cells persist after neoadjuvant chemotherapy in triple negative breast cancer. Breast Cancer Res. 2017 Aug 01; 19(1):88. PMID: 28764807; PMCID: PMC5540189.
    Citations: 12     Fields:    Translation:Humans
  19. Le Gallo M, Rudd ML, Urick ME, Hansen NF, Zhang S, Lozy F, Sgroi DC, Vidal Bel A, Matias-Guiu X, Broaddus RR, Lu KH, Levine DA, Mutch DG, Goodfellow PJ, Salvesen HB, Mullikin JC, Bell DW. Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing. Cancer. 2017 Sep 01; 123(17):3261-3268. PMID: 28485815; PMCID: PMC5587124.
    Citations: 28     Fields:    Translation:Humans
  20. Ebrahimi A, Jung MH, Dreyfuss JM, Pan H, Sgroi D, Bonner-Weir S, Weir GC. Evidence of stress in ß cells obtained with laser capture microdissection from pancreases of brain dead donors. Islets. 2017 03 04; 9(2):19-29. PMID: 28252345.
    Citations: 6     Fields:    Translation:HumansCells
  21. Gupta N, Badeaux M, Liu Y, Naxerova K, Sgroi D, Munn LL, Jain RK, Garkavtsev I. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc Natl Acad Sci U S A. 2017 01 31; 114(5):1033-1038. PMID: 28096337; PMCID: PMC5293063.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  22. Sgroi DC, Brufsky A. Biomarkers for Early-Stage Breast Cancer: Clinical Utility for Extended Adjuvant Treatment Decisions. J Clin Oncol. 2016 11 10; 34(32):3941-3942. PMID: 27551134.
    Citations: 2     Fields:    Translation:Humans
  23. Miles WO, Lembo A, Volorio A, Brachtel E, Tian B, Sgroi D, Provero P, Dyson N. Alternative Polyadenylation in Triple-Negative Breast Tumors Allows NRAS and c-JUN to Bypass PUMILIO Posttranscriptional Regulation. Cancer Res. 2016 12 15; 76(24):7231-7241. PMID: 27758885; PMCID: PMC5553310.
    Citations: 27     Fields:    Translation:HumansCells
  24. Jordan NV, Bardia A, Wittner BS, Benes C, Ligorio M, Zheng Y, Yu M, Sundaresan TK, Licausi JA, Desai R, O'Keefe RM, Ebright RY, Boukhali M, Sil S, Onozato ML, Iafrate AJ, Kapur R, Sgroi D, Ting DT, Toner M, Ramaswamy S, Haas W, Maheswaran S, Haber DA. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016 09 01; 537(7618):102-106. PMID: 27556950; PMCID: PMC5161614.
    Citations: 146     Fields:    Translation:HumansCells
  25. Cotter K, Liberman R, Sun-Wada G, Wada Y, Sgroi D, Naber S, Brown D, Breton S, Forgac M. The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer. Oncotarget. 2016 Jul 19; 7(29):46142-46157. PMID: 27323815.
    Citations: 21     Fields:    Translation:HumansCells
  26. Sestak I, Zhang Y, Schroeder BE, Schnabel CA, Dowsett M, Cuzick J, Sgroi D. Cross-Stratification and Differential Risk by Breast Cancer Index and Recurrence Score in Women with Hormone Receptor-Positive Lymph Node-Negative Early-Stage Breast Cancer. Clin Cancer Res. 2016 Oct 15; 22(20):5043-5048. PMID: 27252417.
    Citations: 5     Fields:    Translation:Humans
  27. Chapman JA, Sgroi DC, Goss PE, Zarella E, Binns S, Zhang Y, Schnabel CA, Erlander MG, Pritchard KI, Han L, Badovinac-Crnjevic T, Shepherd LE, Pollak MN. Relapse-free survival of statistically standardized continuous RT-PCR estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2): NCIC CTG MA.14. Breast Cancer Res Treat. 2016 05; 157(1):101-8. PMID: 27116182.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  28. Misra M, Sagar P, Friedmann AM, Ryan DP, Sgroi DC. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 12-2016. An 8-Year-Old Boy with an Enlarging Mass in the Right Breast. N Engl J Med. 2016 Apr 21; 374(16):1565-74. PMID: 27096583.
    Citations:    Fields:    Translation:Humans
  29. Sgroi DC, Chapman JA, Badovinac-Crnjevic T, Zarella E, Binns S, Zhang Y, Schnabel CA, Erlander MG, Pritchard KI, Han L, Shepherd LE, Goss PE, Pollak M. Assessment of the prognostic and predictive utility of the Breast Cancer Index (BCI): an NCIC CTG MA.14 study. Breast Cancer Res. 2016 Jan 04; 18(1):1. PMID: 26728744; PMCID: PMC4700696.
    Citations: 14     Fields:    Translation:Humans
  30. Miyoshi N, Wittner BS, Shioda K, Hitora T, Ito T, Ramaswamy S, Isselbacher KJ, Sgroi DC, Shioda T. Nodes-and-connections RNAi knockdown screening: identification of a signaling molecule network involved in fulvestrant action and breast cancer prognosis. Oncogenesis. 2015 Oct 19; 4:e172. PMID: 26479444; PMCID: PMC4632093.
  31. Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B. Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays. Nat Commun. 2014 Dec 09; 5:5662. PMID: 25489927.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  32. Olsen L, Campos B, Winther O, Sgroi DC, Karger BL, Brusic V. Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas. BMC Med Genomics. 2014; 7 Suppl 3:S2. PMID: 25521819.
    Citations: 4     Fields:    Translation:HumansCells
  33. Rudd ML, Mohamed H, Price JC, O'Hara AJ, Le Gallo M, Urick ME, Cruz P, Zhang S, Hansen NF, Godwin AK, Sgroi DC, Wolfsberg TG, Mullikin JC, Merino MJ, Bell DW. Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1. BMC Cancer. 2014 Nov 26; 14:884. PMID: 25427824; PMCID: PMC4258955.
    Citations: 8     Fields:    Translation:HumansCells
  34. Juric D, Castel P, Griffith M, Griffith OL, Won HH, Ellis H, Ebbesen SH, Ainscough BJ, Ramu A, Iyer G, Shah RH, Huynh T, Mino-Kenudson M, Sgroi D, Isakoff S, Thabet A, Elamine L, Solit DB, Lowe SW, Quadt C, Peters M, Derti A, Schegel R, Huang A, Mardis ER, Berger MF, Baselga J, Scaltriti M. Convergent loss of PTEN leads to clinical resistance to a PI(3)Ka inhibitor. Nature. 2015 Feb 12; 518(7538):240-4. PMID: 25409150.
    Citations: 230     Fields:    Translation:HumansAnimals
  35. Yu M, Bardia A, Aceto N, Bersani F, Madden MW, Donaldson MC, Desai R, Zhu H, Comaills V, Zheng Z, Wittner BS, Stojanov P, Brachtel E, Sgroi D, Kapur R, Shioda T, Ting DT, Ramaswamy S, Getz G, Iafrate AJ, Benes C, Toner M, Maheswaran S, Haber DA. Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility. Science. 2014 Jul 11; 345(6193):216-20. PMID: 25013076; PMCID: PMC4358808.
    Citations: 378     Fields:    Translation:HumansAnimalsCells
  36. Aguilar H, Urruticoechea A, Halonen P, Kiyotani K, Mushiroda T, Barril X, Serra-Musach J, Islam A, Caizzi L, Di Croce L, Nevedomskaya E, Zwart W, Bostner J, Karlsson E, Pérez Tenorio G, Fornander T, Sgroi DC, Garcia-Mata R, Jansen MP, García N, Bonifaci N, Climent F, Soler MT, Rodríguez-Vida A, Gil M, Brunet J, Martrat G, Gómez-Baldó L, Extremera AI, Figueras A, Balart J, Clarke R, Burnstein KL, Carlson KE, Katzenellenbogen JA, Vizoso M, Esteller M, Villanueva A, Rodríguez-Peña AB, Bustelo XR, Nakamura Y, Zembutsu H, Stål O, Beijersbergen RL, Pujana MA. VAV3 mediates resistance to breast cancer endocrine therapy. Breast Cancer Res. 2014 May 28; 16(3):R53. PMID: 24886537.
    Citations: 15     Fields:    Translation:HumansCells
  37. Sjöström M, Hartman L, Grabau D, Fornander T, Malmström P, Nordenskjöld B, Sgroi DC, Skoog L, Stål O, Leeb-Lundberg LM, Fernö M. Lack of G protein-coupled estrogen receptor (GPER) in the plasma membrane is associated with excellent long-term prognosis in breast cancer. Breast Cancer Res Treat. 2014 May; 145(1):61-71. PMID: 24715381.
    Citations: 32     Fields:    Translation:HumansCells
  38. McMullin RP, Wittner BS, Yang C, Denton-Schneider BR, Hicks D, Singavarapu R, Moulis S, Lee J, Akbari MR, Narod SA, Aldape KD, Steeg PS, Ramaswamy S, Sgroi DC. A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity. Breast Cancer Res. 2014 Mar 14; 16(2):R25. PMID: 24625110.
    Citations: 33     Fields:    Translation:HumansCells
  39. Wong JS, Chen YH, Gadd MA, Gelman R, Lester SC, Schnitt SJ, Sgroi DC, Silver BJ, Smith BL, Troyan SL, Harris JR. Eight-year update of a prospective study of wide excision alone for small low- or intermediate-grade ductal carcinoma in situ (DCIS). Breast Cancer Res Treat. 2014 Jan; 143(2):343-50. PMID: 24346130.
    Citations: 29     Fields:    Translation:HumansCTClinical Trials
  40. Sgroi DC, Sestak I, Cuzick J, Zhang Y, Schnabel CA, Schroeder B, Erlander MG, Dunbier A, Sidhu K, Lopez-Knowles E, Goss PE, Dowsett M. Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in the TransATAC study population. Lancet Oncol. 2013 Oct; 14(11):1067-1076. PMID: 24035531; PMCID: PMC3918681.
    Citations: 130     Fields:    Translation:Humans
  41. Sgroi DC, Carney E, Zarrella E, Steffel L, Binns SN, Finkelstein DM, Szymonifka J, Bhan AK, Shepherd LE, Zhang Y, Schnabel CA, Erlander MG, Ingle JN, Porter P, Muss HB, Pritchard KI, Tu D, Rimm DL, Goss PE. Prediction of late disease recurrence and extended adjuvant letrozole benefit by the HOXB13/IL17BR biomarker. J Natl Cancer Inst. 2013 Jul 17; 105(14):1036-42. PMID: 23812955.
    Citations: 65     Fields:    Translation:Humans
  42. Zhang Y, Schnabel CA, Schroeder BE, Jerevall PL, Jankowitz RC, Fornander T, Stål O, Brufsky AM, Sgroi D, Erlander MG. Breast cancer index identifies early-stage estrogen receptor-positive breast cancer patients at risk for early- and late-distant recurrence. Clin Cancer Res. 2013 Aug 01; 19(15):4196-205. PMID: 23757354.
    Citations: 70     Fields:    Translation:Humans
  43. Price JC, Pollock LM, Rudd ML, Fogoros SK, Mohamed H, Hanigan CL, Le Gallo M, Zhang S, Cruz P, Cherukuri PF, Hansen NF, McManus KJ, Godwin AK, Sgroi DC, Mullikin JC, Merino MJ, Hieter P, Bell DW. Sequencing of candidate chromosome instability genes in endometrial cancers reveals somatic mutations in ESCO1, CHTF18, and MRE11A. PLoS One. 2014; 8(6):e63313. PMID: 23755103.
    Citations: 19     Fields:    Translation:HumansCells
  44. Weiner M, Skoog L, Fornander T, Nordenskjöld B, Sgroi DC, Stål O. Oestrogen receptor co-activator AIB1 is a marker of tamoxifen benefit in postmenopausal breast cancer. Ann Oncol. 2013 Aug; 24(8):1994-9. PMID: 23670096.
    Citations: 8     Fields:    Translation:Humans
  45. Goss PE, Lee BL, Badovinac-Crnjevic T, Strasser-Weippl K, Chavarri-Guerra Y, St Louis J, Villarreal-Garza C, Unger-Saldaña K, Ferreyra M, Debiasi M, Liedke PE, Touya D, Werutsky G, Higgins M, Fan L, Vasconcelos C, Cazap E, Vallejos C, Mohar A, Knaul F, Arreola H, Batura R, Luciani S, Sullivan R, Finkelstein D, Simon S, Barrios C, Kightlinger R, Gelrud A, Bychkovsky V, Lopes G, Stefani S, Blaya M, Souza FH, Santos FS, Kaemmerer A, de Azambuja E, Zorilla AF, Murillo R, Jeronimo J, Tsu V, Carvalho A, Gil CF, Sternberg C, Dueñas-Gonzalez A, Sgroi D, Cuello M, Fresco R, Reis RM, Masera G, Gabús R, Ribeiro R, Knust R, Ismael G, Rosenblatt E, Roth B, Villa L, Solares AL, Leon MX, Torres-Vigil I, Covarrubias-Gomez A, Hernández A, Bertolino M, Schwartsmann G, Santillana S, Esteva F, Fein L, Mano M, Gomez H, Hurlbert M, Durstine A, Azenha G. Planning cancer control in Latin America and the Caribbean. Lancet Oncol. 2013 Apr; 14(5):391-436. PMID: 23628188.
    Citations: 152     Fields:    Translation:Humans
  46. Habel LA, Sakoda LC, Achacoso N, Ma XJ, Erlander MG, Sgroi DC, Fehrenbacher L, Greenberg D, Quesenberry CP. HOXB13:IL17BR and molecular grade index and risk of breast cancer death among patients with lymph node-negative invasive disease. Breast Cancer Res. 2013 Mar 14; 15(2):R24. PMID: 23497539.
    Citations: 12     Fields:    Translation:Humans
  47. Yu M, Bardia A, Wittner BS, Stott SL, Smas ME, Ting DT, Isakoff SJ, Ciciliano JC, Wells MN, Shah AM, Concannon KF, Donaldson MC, Sequist LV, Brachtel E, Sgroi D, Baselga J, Ramaswamy S, Toner M, Haber DA, Maheswaran S. Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science. 2013 Feb 01; 339(6119):580-4. PMID: 23372014.
    Citations: 1084     Fields:    Translation:HumansAnimalsCells
  48. Karlsson E, Pérez-Tenorio G, Amin R, Bostner J, Skoog L, Fornander T, Sgroi DC, Nordenskjöld B, Hallbeck AL, Stål O. The mTOR effectors 4EBP1 and S6K2 are frequently coexpressed, and associated with a poor prognosis and endocrine resistance in breast cancer: a retrospective study including patients from the randomised Stockholm tamoxifen trials. Breast Cancer Res. 2013; 15(5):R96. PMID: 24131622; PMCID: PMC3978839.
    Citations: 48     Fields:    Translation:Humans
  49. Le Gallo M, O'Hara AJ, Rudd ML, Urick ME, Hansen NF, O'Neil NJ, Price JC, Zhang S, England BM, Godwin AK, Sgroi DC, Hieter P, Mullikin JC, Merino MJ, Bell DW. Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes. Nat Genet. 2012 Dec; 44(12):1310-5. PMID: 23104009.
    Citations: 210     Fields:    Translation:HumansCells
  50. Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C, Zou L, Cortes ML, Fernandez-Lopez JC, Peng S, Ardlie KG, Auclair D, Bautista-Piña V, Duke F, Francis J, Jung J, Maffuz-Aziz A, Onofrio RC, Parkin M, Pho NH, Quintanar-Jurado V, Ramos AH, Rebollar-Vega R, Rodriguez-Cuevas S, Romero-Cordoba SL, Schumacher SE, Stransky N, Thompson KM, Uribe-Figueroa L, Baselga J, Beroukhim R, Polyak K, Sgroi DC, Richardson AL, Jimenez-Sanchez G, Lander ES, Gabriel SB, Garraway LA, Golub TR, Melendez-Zajgla J, Toker A, Getz G, Hidalgo-Miranda A, Meyerson M. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature. 2012 Jun 20; 486(7403):405-9. PMID: 22722202.
    Citations: 597     Fields:    Translation:Humans
  51. Imielinski M, Cha S, Rejtar T, Richardson EA, Karger BL, Sgroi DC. Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse. Mol Cell Proteomics. 2012 Jun; 11(6):M111.014910. PMID: 22240506.
    Citations: 16     Fields:    Translation:Humans
  52. Febbo PG, Ladanyi M, Aldape KD, De Marzo AM, Hammond ME, Hayes DF, Iafrate AJ, Kelley RK, Marcucci G, Ogino S, Pao W, Sgroi DC, Birkeland ML. NCCN Task Force report: Evaluating the clinical utility of tumor markers in oncology. J Natl Compr Canc Netw. 2011 Nov; 9 Suppl 5:S1-32; quiz S33. PMID: 22138009.
    Citations: 114     Fields:    Translation:Humans
  53. Sgroi D, Carney E, Richardson E, Steffel L, Binns SN, Finkelstein DM, Shepherd LE, Kesty NC, Schnabel C, Erlander MG, Ingle JN, Porter P, Paik S, Muss HB, Pritchard KI, Tu D, Goss PE. Prediction of late recurrences by breast cancer index in the NCIC CTG MA.17 cohort. J Clin Oncol. 2011 Sep 20; 29(27_suppl):2. PMID: 27958176.
  54. Thakur D, Rejtar T, Wang D, Bones J, Cha S, Clodfelder-Miller B, Richardson E, Binns S, Dahiya S, Sgroi D, Karger BL. Microproteomic analysis of 10,000 laser captured microdissected breast tumor cells using short-range sodium dodecyl sulfate-polyacrylamide gel electrophoresis and porous layer open tubular liquid chromatography tandem mass spectrometry. J Chromatogr A. 2011 Nov 11; 1218(45):8168-74. PMID: 21982995.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  55. Bell DW, Sikdar N, Lee KY, Price JC, Chatterjee R, Park HD, Fox J, Ishiai M, Rudd ML, Pollock LM, Fogoros SK, Mohamed H, Hanigan CL, Zhang S, Cruz P, Renaud G, Hansen NF, Cherukuri PF, Borate B, McManus KJ, Stoepel J, Sipahimalani P, Godwin AK, Sgroi DC, Merino MJ, Elliot G, Elkahloun A, Vinson C, Takata M, Mullikin JC, Wolfsberg TG, Hieter P, Lim DS, Myung K. Predisposition to cancer caused by genetic and functional defects of mammalian Atad5. PLoS Genet. 2011 Aug; 7(8):e1002245. PMID: 21901109.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  56. Lee J, Hirsh AS, Wittner BS, Maeder ML, Singavarapu R, Lang M, Janarthanan S, McDermott U, Yajnik V, Ramaswamy S, Joung JK, Sgroi DC. Induction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor library. PLoS One. 2011; 6(7):e21112. PMID: 21818254.
    Citations: 5     Fields:    Translation:HumansCells
  57. Jin K, Kong X, Shah T, Penet MF, Wildes F, Sgroi DC, Ma XJ, Huang Y, Kallioniemi A, Landberg G, Bieche I, Wu X, Lobie PE, Davidson NE, Bhujwalla ZM, Zhu T, Sukumar S. The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):2736-41. PMID: 21690342.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  58. Perentes JY, Kirkpatrick ND, Nagano S, Smith EY, Shaver CM, Sgroi D, Garkavtsev I, Munn LL, Jain RK, Boucher Y. Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors. Cancer Res. 2011 Jul 01; 71(13):4527-38. PMID: 21571860.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  59. Jerevall PL, Ma XJ, Li H, Salunga R, Kesty NC, Erlander MG, Sgroi DC, Holmlund B, Skoog L, Fornander T, Nordenskjöld B, Stål O. Prognostic utility of HOXB13:IL17BR and molecular grade index in early-stage breast cancer patients from the Stockholm trial. Br J Cancer. 2011 May 24; 104(11):1762-9. PMID: 21559019.
    Citations: 80     Fields:    Translation:Humans
  60. Urick ME, Rudd ML, Godwin AK, Sgroi D, Merino M, Bell DW. PIK3R1 (p85a) is somatically mutated at high frequency in primary endometrial cancer. Cancer Res. 2011 Jun 15; 71(12):4061-7. PMID: 21478295.
    Citations: 91     Fields:    Translation:HumansCells
  61. Rudd ML, Price JC, Fogoros S, Godwin AK, Sgroi DC, Merino MJ, Bell DW. A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas. Clin Cancer Res. 2011 Mar 15; 17(6):1331-40. PMID: 21266528.
    Citations: 110     Fields:    Translation:HumansCells
  62. Jermendy A, Toschi E, Aye T, Koh A, Aguayo-Mazzucato C, Sharma A, Weir GC, Sgroi D, Bonner-Weir S. Rat neonatal beta cells lack the specialised metabolic phenotype of mature beta cells. Diabetologia. 2011 Mar; 54(3):594-604. PMID: 21240476.
    Citations: 66     Fields:    Translation:AnimalsCells
  63. Yang C, Hayashida T, Forster N, Li C, Shen D, Maheswaran S, Chen L, Anderson KS, Ellisen LW, Sgroi D, Schmidt EV. The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers. Cancer Res. 2011 Feb 01; 71(3):937-45. PMID: 21127199.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  64. Bombonati A, Sgroi DC. The molecular pathology of breast cancer progression. J Pathol. 2011 Jan; 223(2):307-17. PMID: 21125683.
    Citations: 123     Fields:    Translation:HumansCells
  65. Tung N, Miron A, Schnitt SJ, Gautam S, Fetten K, Kaplan J, Yassin Y, Buraimoh A, Kim JY, Szász AM, Tian R, Wang ZC, Collins LC, Brock J, Krag K, Legare RD, Sgroi D, Ryan PD, Silver DP, Garber JE, Richardson AL. Prevalence and predictors of loss of wild type BRCA1 in estrogen receptor positive and negative BRCA1-associated breast cancers. Breast Cancer Res. 2010; 12(6):R95. PMID: 21080930.
    Citations: 19     Fields:    Translation:HumansCells
  66. Cha S, Imielinski MB, Rejtar T, Richardson EA, Thakur D, Sgroi DC, Karger BL. In situ proteomic analysis of human breast cancer epithelial cells using laser capture microdissection: annotation by protein set enrichment analysis and gene ontology. Mol Cell Proteomics. 2010 Nov; 9(11):2529-44. PMID: 20739354.
    Citations: 28     Fields:    Translation:HumansCells
  67. Marselli L, Thorne J, Dahiya S, Sgroi DC, Sharma A, Bonner-Weir S, Marchetti P, Weir GC. Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes. PLoS One. 2010 Jul 13; 5(7):e11499. PMID: 20644627.
    Citations: 142     Fields:    Translation:HumansCells
  68. Kennedy J, Katsuta H, Jung MH, Marselli L, Goldfine AB, Balis UJ, Sgroi D, Bonner-Weir S, Weir GC. Protective unfolded protein response in human pancreatic beta cells transplanted into mice. PLoS One. 2010 Jun 18; 5(6):e11211. PMID: 20585452.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  69. Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Tam A, Ma XJ, Erlander M, Sgroi DC, Rocco JW, Lingen MW, Cohen EE, Louis DN, Settleman J, Haber DA. A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res. 2010 Mar 15; 70(6):2158-64. PMID: 20215515; PMCID: PMC2881662.
    Citations: 44     Fields:    Translation:HumansCells
  70. Horak P, Crawford AR, Vadysirisack DD, Nash ZM, DeYoung MP, Sgroi D, Ellisen LW. Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4675-80. PMID: 20176937.
    Citations: 89     Fields:    Translation:HumansAnimalsCells
  71. Tung N, Wang Y, Collins LC, Kaplan J, Li H, Gelman R, Comander AH, Gallagher B, Fetten K, Krag K, Stoeckert KA, Legare RD, Sgroi D, Ryan PD, Garber JE, Schnitt SJ. Estrogen receptor positive breast cancers in BRCA1 mutation carriers: clinical risk factors and pathologic features. Breast Cancer Res. 2010; 12(1):R12. PMID: 20149218.
    Citations: 38     Fields:    Translation:Humans
  72. Silver DP, Richardson AL, Eklund AC, Wang ZC, Szallasi Z, Li Q, Juul N, Leong CO, Calogrias D, Buraimoh A, Fatima A, Gelman RS, Ryan PD, Tung NM, De Nicolo A, Ganesan S, Miron A, Colin C, Sgroi DC, Ellisen LW, Winer EP, Garber JE. Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer. J Clin Oncol. 2010 Mar 01; 28(7):1145-53. PMID: 20100965.
    Citations: 388     Fields:    Translation:HumansCells
  73. Aye T, Toschi E, Sharma A, Sgroi D, Bonner-Weir S. Identification of markers for newly formed beta-cells in the perinatal period: a time of recognized beta-cell immaturity. J Histochem Cytochem. 2010 Apr; 58(4):369-76. PMID: 20051380.
    Citations: 22     Fields:    Translation:AnimalsCells
  74. Sgroi DC. Preinvasive breast cancer. Annu Rev Pathol. 2010; 5:193-221. PMID: 19824828.
    Citations: 42     Fields:    Translation:Humans
  75. Hayashida T, Takahashi F, Chiba N, Brachtel E, Takahashi M, Godin-Heymann N, Gross KW, Vivanco Md, Wijendran V, Shioda T, Sgroi D, Donahoe PK, Maheswaran S. HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis. Proc Natl Acad Sci U S A. 2010 Jan 19; 107(3):1100-5. PMID: 20080567.
    Citations: 84     Fields:    Translation:Humans
  76. Zhang J, Song YH, Brannigan BW, Wahrer DC, Schiripo TA, Harris PL, Haserlat SM, Ulkus LE, Shannon KM, Garber JE, Freedman ML, Henderson BE, Zou L, Sgroi DC, Haber DA, Bell DW. Prevalence and functional analysis of sequence variants in the ATR checkpoint mediator Claspin. Mol Cancer Res. 2009 Sep; 7(9):1510-6. PMID: 19737971.
    Citations: 4     Fields:    Translation:HumansCells
  77. Burstein HJ, Souter I, D'Alessandro HA, Sgroi DC. Case records of the Massachusetts General Hospital. Case 25-2009. A 36-year-old woman with hormone-receptor-positive breast cancer. N Engl J Med. 2009 Aug 13; 361(7):699-707. PMID: 19675333.
    Citations:    Fields:    Translation:HumansPHPublic Health
  78. Willers H, Taghian AG, Luo CM, Treszezamsky A, Sgroi DC, Powell SN. Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies. Mol Cancer Res. 2009 Aug; 7(8):1304-9. PMID: 19671671.
    Citations: 56     Fields:    Translation:HumansCells
  79. Sgroi DC. Breast cancer SRC activity: bad to the bone. Cancer Cell. 2009 Jul 07; 16(1):1-2. PMID: 19573804.
    Citations: 5     Fields:    Translation:Humans
  80. Sgroi DC. The HOXB13:IL17BR gene-expression ratio: a biomarker providing information above and beyond tumor grade. Biomark Med. 2009 Apr; 3(2):99-102. PMID: 20477500.
    Citations: 1     Fields:    
  81. Ma XJ, Dahiya S, Richardson E, Erlander M, Sgroi DC. Gene expression profiling of the tumor microenvironment during breast cancer progression. Breast Cancer Res. 2009; 11(1):R7. PMID: 19187537.
    Citations: 338     Fields:    Translation:HumansCells
  82. Marselli L, Sgroi DC, Bonner-Weir S, Weir GC. Laser capture microdissection of human pancreatic beta-cells and RNA preparation for gene expression profiling. Methods Mol Biol. 2009; 560:87-98. PMID: 19504246.
    Citations: 16     Fields:    Translation:HumansCells
  83. Goetz MP, Suman VJ, Couch FJ, Ames MM, Rae JM, Erlander MG, Ma XJ, Sgroi DC, Reynolds CA, Lingle WL, Weinshilboum RM, Flockhart DA, Desta Z, Perez EA, Ingle JN. Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance. Clin Cancer Res. 2008 Sep 15; 14(18):5864-8. PMID: 18794098.
    Citations: 11     Fields:    Translation:Humans
  84. Ince TA, Ward JM, Valli VE, Sgroi D, Nikitin AY, Loda M, Griffey SM, Crum CP, Crawford JM, Bronson RT, Cardiff RD. Do-it-yourself (DIY) pathology. Nat Biotechnol. 2008 Sep; 26(9):978-9; discussion 979. PMID: 18779800.
    Citations: 16     Fields:    Translation:HumansAnimals
  85. Hao J, Serohijos AW, Newton G, Tassone G, Wang Z, Sgroi DC, Dokholyan NV, Basilion JP. Identification and rational redesign of peptide ligands to CRIP1, a novel biomarker for cancers. PLoS Comput Biol. 2008 Aug 01; 4(8):e1000138. PMID: 18670594.
    Citations: 16     Fields:    Translation:HumansCells
  86. Maeder ML, Thibodeau-Beganny S, Osiak A, Wright DA, Anthony RM, Eichtinger M, Jiang T, Foley JE, Winfrey RJ, Townsend JA, Unger-Wallace E, Sander JD, Müller-Lerch F, Fu F, Pearlberg J, Göbel C, Dassie JP, Pruett-Miller SM, Porteus MH, Sgroi DC, Iafrate AJ, Dobbs D, McCray PB, Cathomen T, Voytas DF, Joung JK. Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol Cell. 2008 Jul 25; 31(2):294-301. PMID: 18657511.
    Citations: 305     Fields:    Translation:HumansCells
  87. Sgroi D, Hameed O, Hattab E, Chang B, Moulis S, Steffel L, Salunga R, Ma X, Erlander M, Goss P. Comparison of risk stratification of ER-positive, node-negative breast cancer patients by Oncotype DX versus molecular grade index and HOXB13/IL17BR ratio. J Clin Oncol. 2008 May 20; 26(15_suppl):22061. PMID: 27950672.
  88. Wittner BS, Sgroi DC, Ryan PD, Bruinsma TJ, Glas AM, Male A, Dahiya S, Habin K, Bernards R, Haber DA, Van't Veer LJ, Ramaswamy S. Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort. Clin Cancer Res. 2008 May 15; 14(10):2988-93. PMID: 18483364.
    Citations: 49     Fields:    Translation:Humans
  89. Ma XJ, Salunga R, Dahiya S, Wang W, Carney E, Durbecq V, Harris A, Goss P, Sotiriou C, Erlander M, Sgroi D. A five-gene molecular grade index and HOXB13:IL17BR are complementary prognostic factors in early stage breast cancer. Clin Cancer Res. 2008 May 01; 14(9):2601-8. PMID: 18451222.
    Citations: 100     Fields:    Translation:Humans
  90. Moulis S, Sgroi DC. Re-evaluating early breast neoplasia. Breast Cancer Res. 2008; 10(1):302. PMID: 18279539.
    Citations: 9     Fields:    Translation:Humans
  91. DeYoung MP, Horak P, Sofer A, Sgroi D, Ellisen LW. Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling. Genes Dev. 2008 Jan 15; 22(2):239-51. PMID: 18198340; PMCID: PMC2192757.
    Citations: 335     Fields:    Translation:HumansAnimalsCells
  92. Bell DW, Kim SH, Godwin AK, Schiripo TA, Harris PL, Haserlat SM, Wahrer DC, Haiman CA, Daly MB, Niendorf KB, Smith MR, Sgroi DC, Garber JE, Olopade OI, Le Marchand L, Henderson BE, Altshuler D, Haber DA, Freedman ML. Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts. Int J Cancer. 2007 Dec 15; 121(12):2661-7. PMID: 17721994; PMCID: PMC3090684.
    Citations: 34     Fields:    Translation:Humans
  93. Marselli L, Thorne J, Ahn YB, Omer A, Sgroi DC, Libermann T, Otu HH, Sharma A, Bonner-Weir S, Weir GC. Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection. J Clin Endocrinol Metab. 2008 Mar; 93(3):1046-53. PMID: 18073315; PMCID: PMC2266961.
    Citations: 41     Fields:    Translation:HumansCells
  94. Wang Z, Dahiya S, Provencher H, Muir B, Carney E, Coser K, Shioda T, Ma XJ, Sgroi DC. The prognostic biomarkers HOXB13, IL17BR, and CHDH are regulated by estrogen in breast cancer. Clin Cancer Res. 2007 Nov 01; 13(21):6327-34. PMID: 17975144.
    Citations: 38     Fields:    Translation:HumansCells
  95. Miao J, Wang Z, Provencher H, Muir B, Dahiya S, Carney E, Leong CO, Sgroi DC, Orsulic S. HOXB13 promotes ovarian cancer progression. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):17093-8. PMID: 17942676.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  96. Smolen GA, Schott BJ, Stewart RA, Diederichs S, Muir B, Provencher HL, Look AT, Sgroi DC, Peterson RT, Haber DA. A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors. Genes Dev. 2007 Sep 01; 21(17):2131-6. PMID: 17704304; PMCID: PMC1950852.
    Citations: 23     Fields:    Translation:Animals
  97. Moran ST, Cariappa A, Liu H, Muir B, Sgroi D, Boboila C, Pillai S. Synergism between NF-kappa B1/p50 and Notch2 during the development of marginal zone B lymphocytes. J Immunol. 2007 Jul 01; 179(1):195-200. PMID: 17579038.
    Citations: 38     Fields:    Translation:AnimalsCells
  98. Leong CO, Vidnovic N, DeYoung MP, Sgroi D, Ellisen LW. The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers. J Clin Invest. 2007 May; 117(5):1370-80. PMID: 17446929; PMCID: PMC1849987.
    Citations: 122     Fields:    Translation:HumansCells
  99. Harris LN, You F, Schnitt SJ, Witkiewicz A, Lu X, Sgroi D, Ryan PD, Come SE, Burstein HJ, Lesnikoski BA, Kamma M, Friedman PN, Gelman R, Iglehart JD, Winer EP. Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer. Clin Cancer Res. 2007 Feb 15; 13(4):1198-207. PMID: 17317830.
    Citations: 84     Fields:    Translation:HumansCTClinical Trials
  100. Ahn YB, Xu G, Marselli L, Toschi E, Sharma A, Bonner-Weir S, Sgroi DC, Weir GC. Changes in gene expression in beta cells after islet isolation and transplantation using laser-capture microdissection. Diabetologia. 2007 Feb; 50(2):334-42. PMID: 17180350.
    Citations: 25     Fields:    Translation:AnimalsCells
  101. Yang C, Trent S, Ionescu-Tiba V, Lan L, Shioda T, Sgroi D, Schmidt EV. Identification of cyclin D1- and estrogen-regulated genes contributing to breast carcinogenesis and progression. Cancer Res. 2006 Dec 15; 66(24):11649-58. PMID: 17178859.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  102. Hartwell KA, Muir B, Reinhardt F, Carpenter AE, Sgroi DC, Weinberg RA. The Spemann organizer gene, Goosecoid, promotes tumor metastasis. Proc Natl Acad Sci U S A. 2006 Dec 12; 103(50):18969-74. PMID: 17142318; PMCID: PMC1748161.
    Citations: 106     Fields:    Translation:HumansAnimalsCells
  103. Ma XJ, Hilsenbeck SG, Wang W, Ding L, Sgroi DC, Bender RA, Osborne CK, Allred DC, Erlander MG. The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer. J Clin Oncol. 2006 Oct 01; 24(28):4611-9. PMID: 17008703.
    Citations: 74     Fields:    Translation:Humans
  104. Overholtzer M, Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX, Brugge JS, Haber DA. Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon. Proc Natl Acad Sci U S A. 2006 Aug 15; 103(33):12405-10. PMID: 16894141; PMCID: PMC1533802.
    Citations: 470     Fields:    Translation:HumansAnimalsCells
  105. Kwak EL, Jankowski J, Thayer SP, Lauwers GY, Brannigan BW, Harris PL, Okimoto RA, Haserlat SM, Driscoll DR, Ferry D, Muir B, Settleman J, Fuchs CS, Kulke MH, Ryan DP, Clark JW, Sgroi DC, Haber DA, Bell DW. Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas. Clin Cancer Res. 2006 Jul 15; 12(14 Pt 1):4283-7. PMID: 16857803; PMCID: PMC3807136.
    Citations: 59     Fields:    Translation:HumansCells
  106. Smolen GA, Muir B, Mohapatra G, Barmettler A, Kim WJ, Rivera MN, Haserlat SM, Okimoto RA, Kwak E, Dahiya S, Garber JE, Bell DW, Sgroi DC, Chin L, Deng CX, Haber DA. Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis. Cancer Res. 2006 Apr 01; 66(7):3452-5. PMID: 16585167.
    Citations: 22     Fields:    Translation:AnimalsCells
  107. Ma XJ, Patel R, Wang X, Salunga R, Murage J, Desai R, Tuggle JT, Wang W, Chu S, Stecker K, Raja R, Robin H, Moore M, Baunoch D, Sgroi D, Erlander M. Molecular classification of human cancers using a 92-gene real-time quantitative polymerase chain reaction assay. Arch Pathol Lab Med. 2006 Apr; 130(4):465-73. PMID: 16594740.
    Citations: 79     Fields:    Translation:Humans
  108. Goetz MP, Suman VJ, Ingle JN, Nibbe AM, Visscher DW, Reynolds CA, Lingle WL, Erlander M, Ma XJ, Sgroi DC, Perez EA, Couch FJ. A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen. Clin Cancer Res. 2006 Apr 01; 12(7 Pt 1):2080-7. PMID: 16609019.
    Citations: 44     Fields:    Translation:HumansCTClinical Trials
  109. Wong JS, Kaelin CM, Troyan SL, Gadd MA, Gelman R, Lester SC, Schnitt SJ, Sgroi DC, Silver BJ, Harris JR, Smith BL. Prospective study of wide excision alone for ductal carcinoma in situ of the breast. J Clin Oncol. 2006 Mar 01; 24(7):1031-6. PMID: 16461781.
    Citations: 43     Fields:    Translation:HumansCTClinical Trials
  110. Smolen GA, Sordella R, Muir B, Mohapatra G, Barmettler A, Archibald H, Kim WJ, Okimoto RA, Bell DW, Sgroi DC, Christensen JG, Settleman J, Haber DA. Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2316-21. PMID: 16461907; PMCID: PMC1413705.
    Citations: 219     Fields:    Translation:HumansCells
  111. Frackelton AR, Lu L, Davol PA, Bagdasaryan R, Hafer LJ, Sgroi DC. p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy. Breast Cancer Res. 2006; 8(6):R73. PMID: 17196107; PMCID: PMC1797038.
    Citations: 10     Fields:    Translation:HumansCells
  112. Gunawardane RN, Sgroi DC, Wrobel CN, Koh E, Daley GQ, Brugge JS. Novel role for PDEF in epithelial cell migration and invasion. Cancer Res. 2005 Dec 15; 65(24):11572-80. PMID: 16357167; PMCID: PMC2919290.
    Citations: 39     Fields:    Translation:HumansCells
  113. Michaelson JS, Cheongsiatmoy JA, Dewey F, Silverstein MJ, Sgroi D, Smith B, Tanabe KK. Spread of human cancer cells occurs with probabilities indicative of a nongenetic mechanism. Br J Cancer. 2005 Nov 28; 93(11):1244-9. PMID: 16278668; PMCID: PMC2361524.
    Citations: 10     Fields:    Translation:HumansCells
  114. Cohen EE, Lingen MW, Martin LE, Harris PL, Brannigan BW, Haserlat SM, Okimoto RA, Sgroi DC, Dahiya S, Muir B, Clark JR, Rocco JW, Vokes EE, Haber DA, Bell DW. Response of some head and neck cancers to epidermal growth factor receptor tyrosine kinase inhibitors may be linked to mutation of ERBB2 rather than EGFR. Clin Cancer Res. 2005 Nov 15; 11(22):8105-8. PMID: 16299242.
    Citations: 48     Fields:    Translation:HumansCells
  115. Bell DW, Lynch TJ, Haserlat SM, Harris PL, Okimoto RA, Brannigan BW, Sgroi DC, Muir B, Riemenschneider MJ, Iacona RB, Krebs AD, Johnson DH, Giaccone G, Herbst RS, Manegold C, Fukuoka M, Kris MG, Baselga J, Ochs JS, Haber DA. Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials. J Clin Oncol. 2005 Nov 01; 23(31):8081-92. PMID: 16204011.
    Citations: 165     Fields:    Translation:HumansCTClinical Trials
  116. Ryan PD, Kopans DB, Sgroi DC. Case records of the Massachusetts General Hospital. Case 24-2005. A 58-year-old woman with early-stage estrogen-receptor-positive breast cancer. N Engl J Med. 2005 Aug 11; 353(6):617-22. PMID: 16093471.
    Citations:    Fields:    Translation:Humans
  117. Collins NL, Reginato MJ, Paulus JK, Sgroi DC, Labaer J, Brugge JS. G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression. Mol Cell Biol. 2005 Jun; 25(12):5282-91. PMID: 15923641; PMCID: PMC1140593.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  118. Petricoin EF, Bichsel VE, Calvert VS, Espina V, Winters M, Young L, Belluco C, Trock BJ, Lippman M, Fishman DA, Sgroi DC, Munson PJ, Esserman LJ, Liotta LA. Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy. J Clin Oncol. 2005 May 20; 23(15):3614-21. PMID: 15908672.
    Citations: 50     Fields:    Translation:HumansCells
  119. Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 2005 May 06; 121(3):335-48. PMID: 15882617.
    Citations: 1558     Fields:    Translation:HumansAnimalsCells
  120. Sgroi DC, Haber DA, Ryan PD, Ma XJ, Erlander MG. RE: A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell. 2004 Nov; 6(5):445. PMID: 15542428.
    Citations: 3     Fields:    Translation:Humans
  121. Sgroi DC, Ma XJ, Ryan P, Wang Z, Younger J, Isakoff S, Smith B, Brugge J, Baer TM, Erlander MG. Discovery of new gene expression predictors for adjuvant tamoxifen outcome for breast cancer patients. J Clin Oncol. 2004 Jul 15; 22(14_suppl):9503. PMID: 28016805.
  122. Erlander MG, Moore MW, Cotter P, Reyes M, Stahl R, Hamati H, Ma XJ, Bloom K, Sgroi D, Baunoch D. Molecular classification of carcinoma of unknown primary by gene expression profiling from formalin-fixed paraffin-embedded tissues. J Clin Oncol. 2004 Jul 15; 22(14_suppl):9545. PMID: 28016873.
  123. Lechpammer M, Sgroi DC. Laser Capture Microdissection: a rising tool in genetic profiling of cancer. Expert Rev Mol Diagn. 2004 Jul; 4(4):429-30. PMID: 15225089.
    Citations: 1     Fields:    Translation:Humans
  124. Ma XJ, Wang Z, Ryan PD, Isakoff SJ, Barmettler A, Fuller A, Muir B, Mohapatra G, Salunga R, Tuggle JT, Tran Y, Tran D, Tassin A, Amon P, Wang W, Wang W, Enright E, Stecker K, Estepa-Sabal E, Smith B, Younger J, Balis U, Michaelson J, Bhan A, Habin K, Baer TM, Brugge J, Haber DA, Erlander MG, Sgroi DC. A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell. 2004 Jun; 5(6):607-16. PMID: 15193263.
    Citations: 312     Fields:    Translation:HumansCells
  125. Zang L, Palmer Toy D, Hancock WS, Sgroi DC, Karger BL. Proteomic analysis of ductal carcinoma of the breast using laser capture microdissection, LC-MS, and 16O/18O isotopic labeling. J Proteome Res. 2004 May-Jun; 3(3):604-12. PMID: 15253443.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  126. Yang C, Ionescu-Tiba V, Burns K, Gadd M, Zukerberg L, Louis DN, Sgroi D, Schmidt EV. The role of the cyclin D1-dependent kinases in ErbB2-mediated breast cancer. Am J Pathol. 2004 Mar; 164(3):1031-8. PMID: 14982856; PMCID: PMC1614725.
    Citations: 13     Fields:    Translation:HumansAnimals
  127. Rabban JT, Sgroi DC. Sclerosing lesions of the breast. Semin Diagn Pathol. 2004 Feb; 21(1):42-7. PMID: 15074558.
    Citations: 1     Fields:    Translation:Humans
  128. Michaelson JS, Silverstein M, Sgroi D, Cheongsiatmoy JA, Taghian A, Powell S, Hughes K, Comegno A, Tanabe KK, Smith B. The effect of tumor size and lymph node status on breast carcinoma lethality. Cancer. 2003 Nov 15; 98(10):2133-43. PMID: 14601082.
    Citations: 34     Fields:    Translation:Humans
  129. Högemann-Savellano D, Bos E, Blondet C, Sato F, Abe T, Josephson L, Weissleder R, Gaudet J, Sgroi D, Peters PJ, Basilion JP. The transferrin receptor: a potential molecular imaging marker for human cancer. Neoplasia. 2003 Nov-Dec; 5(6):495-506. PMID: 14965443.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  130. Reynolds PA, Smolen GA, Palmer RE, Sgroi D, Yajnik V, Gerald WL, Haber DA. Identification of a DNA-binding site and transcriptional target for the EWS-WT1(+KTS) oncoprotein. Genes Dev. 2003 Sep 01; 17(17):2094-107. PMID: 12923058; PMCID: PMC196452.
    Citations: 18     Fields:    Translation:HumansCells
  131. Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J, Muthuswamy SK, Brugge JS. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nat Cell Biol. 2003 Aug; 5(8):733-40. PMID: 12844146.
    Citations: 222     Fields:    Translation:HumansAnimalsCells
  132. Fuller AP, Palmer-Toy D, Erlander MG, Sgroi DC. Laser capture microdissection and advanced molecular analysis of human breast cancer. J Mammary Gland Biol Neoplasia. 2003 Jul; 8(3):335-45. PMID: 14973377.
    Citations: 11     Fields:    Translation:Humans
  133. Ma XJ, Salunga R, Tuggle JT, Gaudet J, Enright E, McQuary P, Payette T, Pistone M, Stecker K, Zhang BM, Zhou YX, Varnholt H, Smith B, Gadd M, Chatfield E, Kessler J, Baer TM, Erlander MG, Sgroi DC. Gene expression profiles of human breast cancer progression. Proc Natl Acad Sci U S A. 2003 May 13; 100(10):5974-9. PMID: 12714683; PMCID: PMC156311.
    Citations: 351     Fields:    Translation:HumansCells
  134. Wulfkuhle JD, Sgroi DC, Krutzsch H, McLean K, McGarvey K, Knowlton M, Chen S, Shu H, Sahin A, Kurek R, Wallwiener D, Merino MJ, Petricoin EF, Zhao Y, Steeg PS. Proteomics of human breast ductal carcinoma in situ. Cancer Res. 2002 Nov 15; 62(22):6740-9. PMID: 12438275.
    Citations: 75     Fields:    Translation:Humans
  135. Talora C, Sgroi DC, Crum CP, Dotto GP. Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation. Genes Dev. 2002 Sep 01; 16(17):2252-63. PMID: 12208848; PMCID: PMC186663.
    Citations: 100     Fields:    Translation:HumansCells
  136. Elkahloun AG, Gaudet J, Robinson GS, Sgroi DC. In situ gene expression analysis of cancer using laser capture microdissection, microarrays and real time quantitative PCR. Cancer Biol Ther. 2002 Jul-Aug; 1(4):354-8. PMID: 12432245.
    Citations: 7     Fields:    Translation:Humans
  137. Bell DW, Erban J, Sgroi DC, Haber DA. Selective loss of heterozygosity in multiple breast cancers from a carrier of mutations in both BRCA1 and BRCA2. Cancer Res. 2002 May 15; 62(10):2741-3. PMID: 12019146.
    Citations: 10     Fields:    Translation:Humans
  138. Laybutt DR, Kaneto H, Hasenkamp W, Grey S, Jonas JC, Sgroi DC, Groff A, Ferran C, Bonner-Weir S, Sharma A, Weir GC. Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia. Diabetes. 2002 Feb; 51(2):413-23. PMID: 11812749.
    Citations: 50     Fields:    Translation:Animals
  139. Laybutt DR, Sharma A, Sgroi DC, Gaudet J, Bonner-Weir S, Weir GC. Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia. J Biol Chem. 2002 Mar 29; 277(13):10912-21. PMID: 11782487.
    Citations: 67     Fields:    Translation:AnimalsCells
  140. Enerbäck C, Porter DA, Seth P, Sgroi D, Gaudet J, Weremowicz S, Morton CC, Schnitt S, Pitts RL, Stampl J, Barnhart K, Polyak K. Psoriasin expression in mammary epithelial cells in vitro and in vivo. Cancer Res. 2002 Jan 01; 62(1):43-7. PMID: 11782356.
    Citations: 32     Fields:    Translation:HumansCells
  141. Lee SB, Kim SH, Bell DW, Wahrer DC, Schiripo TA, Jorczak MM, Sgroi DC, Garber JE, Li FP, Nichols KE, Varley JM, Godwin AK, Shannon KM, Harlow E, Haber DA. Destabilization of CHK2 by a missense mutation associated with Li-Fraumeni Syndrome. Cancer Res. 2001 Nov 15; 61(22):8062-7. PMID: 11719428.
    Citations: 39     Fields:    Translation:HumansCells
  142. Wulfkuhle JD, McLean KC, Paweletz CP, Sgroi DC, Trock BJ, Steeg PS, Petricoin EF. New approaches to proteomic analysis of breast cancer. Proteomics. 2001 Oct; 1(10):1205-15. PMID: 11721633.
    Citations: 32     Fields:    Translation:HumansPHPublic Health
  143. Porter DA, Krop IE, Nasser S, Sgroi D, Kaelin CM, Marks JR, Riggins G, Polyak K. A SAGE (serial analysis of gene expression) view of breast tumor progression. Cancer Res. 2001 Aug 01; 61(15):5697-702. PMID: 11479200.
    Citations: 67     Fields:    Translation:Humans
  144. Krop IE, Sgroi D, Porter DA, Lunetta KL, LeVangie R, Seth P, Kaelin CM, Rhei E, Bosenberg M, Schnitt S, Marks JR, Pagon Z, Belina D, Razumovic J, Polyak K. HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9796-801. PMID: 11481438; PMCID: PMC55532.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  145. Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell. 2001 Apr 06; 105(1):149-60. PMID: 11301010.
    Citations: 292     Fields:    Translation:HumansCells
  146. Hartsough MT, Clare SE, Mair M, Elkahloun AG, Sgroi D, Osborne CK, Clark G, Steeg PS. Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition. Cancer Res. 2001 Mar 01; 61(5):2320-7. PMID: 11280805.
    Citations: 32     Fields:    Translation:HumansCells
  147. Easson AM, Pawlik TM, Fischer CP, Conroy JL, Sgroi D, Souba WW, Bode BP. Tumor-influenced amino acid transport activities in zonal-enriched hepatocyte populations. Am J Physiol Gastrointest Liver Physiol. 2000 Dec; 279(6):G1209-18. PMID: 11093943.
    Citations:    Fields:    Translation:Animals
  148. Palmer-Toy DE, Sarracino DA, Sgroi D, LeVangie R, Leopold PE. Direct acquisition of matrix-assisted laser Desorption/Ionization time-of-flight mass spectra from laser capture microdissected tissues Clin Chem. 2000 Sep; 46(9):1513-6. PMID: 10973907.
    Citations: 16     Fields:    
  149. Sgroi DC, Teng S, Robinson G, LeVangie R, Hudson JR, Elkahloun AG. In vivo gene expression profile analysis of human breast cancer progression. Cancer Res. 1999 Nov 15; 59(22):5656-61. PMID: 10582678.
    Citations: 88     Fields:    Translation:Humans
  150. Barnes YC, Skelton TP, Stamenkovic I, Sgroi DC. Sialylation of the sialic acid binding lectin sialoadhesin regulates its ability to mediate cell adhesion. Blood. 1999 Feb 15; 93(4):1245-52. PMID: 9949167.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  151. Crocker PR, Clark EA, Filbin M, Gordon S, Jones Y, Kehrl JH, Kelm S, Le Douarin N, Powell L, Roder J, Schnaar RL, Sgroi DC, Stamenkovic K, Schauer R, Schachner M, van den Berg TK, van der Merwe PA, Watt SM, Varki A. Siglecs: a family of sialic-acid binding lectins. Glycobiology. 1998 Feb; 8(2):v. PMID: 9498912.
    Citations: 65     Fields:    Translation:HumansAnimals
  152. Hulka CA, Edmister WB, Smith BL, Tan L, Sgroi DC, Campbell T, Kopans DB, Weisskoff RM. Dynamic echo-planar imaging of the breast: experience in diagnosing breast carcinoma and correlation with tumor angiogenesis. Radiology. 1997 Dec; 205(3):837-42. PMID: 9393545.
    Citations: 19     Fields:    Translation:Humans
  153. Sgroi D, Nocks A, Stamenkovic I. A single N-linked glycosylation site is implicated in the regulation of ligand recognition by the I-type lectins CD22 and CD33. J Biol Chem. 1996 Aug 02; 271(31):18803-9. PMID: 8702538.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  154. FitzGerald MG, MacDonald DJ, Krainer M, Hoover I, O'Neil E, Unsal H, Silva-Arrieto S, Finkelstein DM, Beer-Romero P, Englert C, Sgroi DC, Smith BL, Younger JW, Garber JE, Duda RB, Mayzel KA, Isselbacher KJ, Friend SH, Haber DA. Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer. N Engl J Med. 1996 Jan 18; 334(3):143-9. PMID: 8531968.
    Citations: 69     Fields:    Translation:HumansCells
  155. Sgroi D, Koerner FC. Involvement of collagenous spherulosis by lobular carcinoma in situ. Potential confusion with cribriform ductal carcinoma in situ. Am J Surg Pathol. 1995 Dec; 19(12):1366-70. PMID: 7503359.
    Citations: 2     Fields:    Translation:Humans
  156. Hulka CA, Smith BL, Sgroi DC, Tan L, Edmister WB, Semple JP, Campbell T, Kopans DB, Brady TJ, Weisskoff RM. Benign and malignant breast lesions: differentiation with echo-planar MR imaging. Radiology. 1995 Oct; 197(1):33-8. PMID: 7568850.
    Citations: 24     Fields:    Translation:Humans
  157. Sgroi D, Koretzky GA, Stamenkovic I. Regulation of CD45 engagement by the B-cell receptor CD22. Proc Natl Acad Sci U S A. 1995 Apr 25; 92(9):4026-30. PMID: 7537381; PMCID: PMC42095.
    Citations: 22     Fields:    Translation:HumansCells
  158. Xu L, Sgroi D, Sterner CJ, Beauchamp RL, Pinney DM, Keel S, Ueki K, Rutter JL, Buckler AJ, Louis DN, et al. Mutational analysis of CDKN2 (MTS1/p16ink4) in human breast carcinomas. Cancer Res. 1994 Oct 15; 54(20):5262-4. PMID: 7923151.
    Citations: 31     Fields:    Translation:HumansCells
  159. Sgroi D, Stamenkovic I. The B-cell adhesion molecule CD22 is cross-species reactive and recognizes distinct sialoglycoproteins on different functional T-cell sub-populations. Scand J Immunol. 1994 May; 39(5):433-8. PMID: 8191218.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  160. Powell LD, Sgroi D, Sjoberg ER, Stamenkovic I, Varki A. Natural ligands of the B cell adhesion molecule CD22 beta carry N-linked oligosaccharides with alpha-2,6-linked sialic acids that are required for recognition. J Biol Chem. 1993 Apr 05; 268(10):7019-27. PMID: 8463235.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  161. Sgroi D, Varki A, Braesch-Andersen S, Stamenkovic I. CD22, a B cell-specific immunoglobulin superfamily member, is a sialic acid-binding lectin. J Biol Chem. 1993 Apr 05; 268(10):7011-8. PMID: 8463234.
    Citations: 57     Fields:    Translation:AnimalsCells
  162. Aruffo A, Kanner SB, Sgroi D, Ledbetter JA, Stamenkovic I. CD22-mediated stimulation of T cells regulates T-cell receptor/CD3-induced signaling. Proc Natl Acad Sci U S A. 1992 Nov 01; 89(21):10242-6. PMID: 1438211; PMCID: PMC50314.
    Citations: 20     Fields:    Translation:HumansCells
  163. Stamenkovic I, Sgroi D, Aruffo A. CD22 binds to alpha-2,6-sialyltransferase-dependent epitopes on COS cells. Cell. 1992 Mar 20; 68(6):1003-4. PMID: 1372195.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  164. Stamenkovic I, Sgroi D, Aruffo A, Sy MS, Anderson T. The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and alpha 2-6 sialyltransferase, CD75, on B cells. Cell. 1991 Sep 20; 66(6):1133-44. PMID: 1717156.
    Citations: 67     Fields:    Translation:HumansCells
  165. Love JT, Padula SJ, Lingenheld EG, Amin JK, Sgroi DC, Wong RL, Sha'fi RI, Clark RB. Effects of H-7 are not exclusively mediated through protein kinase C or the cyclic nucleotide-dependent kinases. Biochem Biophys Res Commun. 1989 Jul 14; 162(1):138-43. PMID: 2546543.
    Citations: 2     Fields:    Translation:AnimalsCells
  166. Padula SJ, Sgroi DC, Lingenheld EG, Love JT, Chou CH, Clark RB. T cell receptor beta chain gene rearrangement shared by murine T cell lines derived from a site of autoimmune inflammation. J Clin Invest. 1988 Jun; 81(6):1810-8. PMID: 2454949; PMCID: PMC442629.
    Citations: 4     Fields:    Translation:AnimalsCells
  167. Clark RB, Love JT, Sgroi D, Lingenheld EG, Sha'afi RI. The protein kinase C inhibitor H-7, inhibits antigen and IL-2-induced proliferation of murine T cell lines. Biochem Biophys Res Commun. 1987 Jun 15; 145(2):666-72. PMID: 2439080.
    Citations: 5     Fields:    Translation:AnimalsCells
  168. Sgroi D, Cohen RN, Lingenheld EG, Strong MK, Binder T, Goldschneider I, Greiner D, Grunnet M, Clark RB. T cell lines derived from the spinal cords of mice with experimental allergic encephalomyelitis are self reactive. J Immunol. 1986 Sep 15; 137(6):1850-4. PMID: 2427582.
    Citations: 7     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.