Harvard Catalyst Profiles

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Gewei Lian, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lian G, Wong T, Lu J, Hu J, Zhang J, Sheen V. Cytoskeletal Associated Filamin A and RhoA Affect Neural Progenitor Specification During Mitosis. Cereb Cortex. 2019 Mar 01; 29(3):1280-1290. PMID: 29462287.
    Citations:    Fields:    
  2. Lian G, Chenn A, Ekuta V, Kanaujia S, Sheen V. Formin 2 Regulates Lysosomal Degradation of Wnt-Associated ß-Catenin in Neural Progenitors. Cereb Cortex. 2018 Apr 05. PMID: 29659741.
    Citations:    Fields:    
  3. Lian G, Kanaujia S, Wong T, Sheen V. FilaminA and Formin2 regulate skeletal, muscular, and intestinal formation through mesenchymal progenitor proliferation. PLoS One. 2017; 12(12):e0189285. PMID: 29240780.
    Citations:    Fields:    Translation:AnimalsCells
  4. Hu J, Lu J, Goyal A, Wong T, Lian G, Zhang J, Hecht JL, Feng Y, Sheen VL. Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading. Hum Mol Genet. 2017 04 01; 26(7):1294-1304. PMID: 28175289.
    Citations: 2     Fields:    Translation:HumansCells
  5. Lian G, Dettenhofer M, Lu J, Downing M, Chenn A, Wong T, Sheen V. Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Development. 2016 12 01; 143(23):4509-4520. PMID: 27789627.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Lu J, Mccarter M, Lian G, Esposito G, Capoccia E, Delli-Bovi LC, Hecht J, Sheen V. Global hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression. Hum Mol Genet. 2016 05 01; 25(9):1714-27. PMID: 26911678; PMCID: PMC4986328.
    Citations: 3     Fields:    Translation:HumansCells
  7. Lian G, Sheen VL. Cytoskeletal proteins in cortical development and disease: actin associated proteins in periventricular heterotopia. Front Cell Neurosci. 2015; 9:99. PMID: 25883548; PMCID: PMC4381626.
    Citations: 13     
  8. Hu J, Lu J, Lian G, Ferland RJ, Dettenhofer M, Sheen VL. Formin 1 and filamin B physically interact to coordinate chondrocyte proliferation and differentiation in the growth plate. Hum Mol Genet. 2014 Sep 01; 23(17):4663-73. PMID: 24760772; PMCID: PMC4119417.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  9. Hu J, Lu J, Lian G, Zhang J, Hecht JL, Sheen VL. Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling. PLoS One. 2014; 9(2):e89352. PMID: 24551245; PMCID: PMC3925234.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  10. Zhang J, Neal J, Lian G, Hu J, Lu J, Sheen V. Filamin A regulates neuronal migration through brefeldin A-inhibited guanine exchange factor 2-dependent Arf1 activation. J Neurosci. 2013 Oct 02; 33(40):15735-46. PMID: 24089482; PMCID: PMC3787497.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  11. Zhang J, Neal J, Lian G, Shi B, Ferland RJ, Sheen V. Brefeldin A-inhibited guanine exchange factor 2 regulates filamin A phosphorylation and neuronal migration. J Neurosci. 2012 Sep 05; 32(36):12619-29. PMID: 22956851; PMCID: PMC3478955.
    Citations: 21     Fields:    Translation:AnimalsCells
  12. Lian G, Lu J, Hu J, Zhang J, Cross SH, Ferland RJ, Sheen VL. Filamin a regulates neural progenitor proliferation and cortical size through Wee1-dependent Cdk1 phosphorylation. J Neurosci. 2012 May 30; 32(22):7672-84. PMID: 22649246; PMCID: PMC3368379.
    Citations: 24     Fields:    Translation:AnimalsCells
  13. Lu J, Lian G, Zhou H, Esposito G, Steardo L, Delli-Bovi LC, Hecht JL, Lu QR, Sheen V. OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors. Hum Mol Genet. 2012 May 15; 21(10):2330-40. PMID: 22343408; PMCID: PMC3335315.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  14. Ferland RJ, Batiz LF, Neal J, Lian G, Bundock E, Lu J, Hsiao YC, Diamond R, Mei D, Banham AH, Brown PJ, Vanderburg CR, Joseph J, Hecht JL, Folkerth R, Guerrini R, Walsh CA, Rodriguez EM, Sheen VL. Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia. Hum Mol Genet. 2009 Feb 01; 18(3):497-516. PMID: 18996916; PMCID: PMC2722192.
    Citations: 60     Fields:    Translation:HumansAnimalsCells
  15. Lu J, Lian G, Lenkinski R, De Grand A, Vaid RR, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V. Filamin B mutations cause chondrocyte defects in skeletal development. Hum Mol Genet. 2007 Jul 15; 16(14):1661-75. PMID: 17510210.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  16. Lian G, Sheen V. Cerebral developmental disorders. Curr Opin Pediatr. 2006 Dec; 18(6):614-20. PMID: 17099359.
    Citations: 14     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.