Harvard Catalyst Profiles

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Russell Paul Goodman, M.D., D.Phil.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. K08DK115881 (GOODMAN, RUSSELL PAUL) Sep 1, 2018 - Jul 31, 2023
    NIH
    A METABOLIC BIOMARKER OF HEPATIC NADH/NAD+ RATIO
    Role: Principal Investigator
  2. F32DK111132 (GOODMAN, RUSSELL PAUL) Aug 1, 2016 - Jul 31, 2017
    NIH
    Compartment-Specific NAD+ Regeneration in Alcohol-Induced Liver Disease
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Vannier AGL, Przybyszewski EM, Shay J, Patel SJ, Schaefer E, Goodman RP, Luther J. Psychotherapy for Alcohol Use Disorder Is Associated With Reduced Risk of Incident Alcohol-Associated Liver Disease. Clin Gastroenterol Hepatol. 2022 Aug 11. PMID: 35964893; PMCID: PMC9918606.
    Citations:    Fields:    
  2. Luther J, Vannier AG, Schaefer EA, Goodman RP. The circulating proteomic signature of alcohol-associated liver disease. JCI Insight. 2022 07 22; 7(14). PMID: 35866482; PMCID: PMC9431701.
    Citations:    Fields:    Translation:Humans
  3. Vannier AGL, Shay JES, Fomin V, Patel SJ, Schaefer E, Goodman RP, Luther J. Incidence and Progression of Alcohol-Associated Liver Disease After Medical Therapy for Alcohol Use Disorder. JAMA Netw Open. 2022 05 02; 5(5):e2213014. PMID: 35594048; PMCID: PMC9123494.
    Citations:    Fields:    Translation:Humans
  4. Vannier AGL, Fomin V, Chung RT, Patel SJ, Schaefer E, Goodman RP, Luther J. Substance use disorder is associated with alcohol-associated liver disease in patients with alcohol use disorder. Gastro Hep Adv. 2022; 1(3):403-408. PMID: 35474707; PMCID: PMC9038113.
    Citations:    
  5. Vannier AGL, PeBenito A, Fomin V, Chung RT, Schaefer E, Goodman RP, Luther J. An exploratory analysis of the competing effects of alcohol use and advanced hepatic fibrosis on serum HDL. Clin Exp Med. 2022 Feb; 22(1):103-110. PMID: 34212294; PMCID: PMC8863747.
    Citations:    Fields:    Translation:Humans
  6. Rath S, Sharma R, Gupta R, Ast T, Chan C, Durham TJ, Goodman RP, Grabarek Z, Haas ME, Hung WHW, Joshi PR, Jourdain AA, Kim SH, Kotrys AV, Lam SS, McCoy JG, Meisel JD, Miranda M, Panda A, Patgiri A, Rogers R, Sadre S, Shah H, Skinner OS, To TL, Walker MA, Wang H, Ward PS, Wengrod J, Yuan CC, Calvo SE, Mootha VK. MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations. Nucleic Acids Res. 2021 01 08; 49(D1):D1541-D1547. PMID: 33174596; PMCID: PMC7778944.
    Citations: 116     Fields:    Translation:HumansAnimalsCells
  7. Goodman RP, Markhard AL, Shah H, Sharma R, Skinner OS, Clish CB, Deik A, Patgiri A, Hsu YH, Masia R, Noh HL, Suk S, Goldberger O, Hirschhorn JN, Yellen G, Kim JK, Mootha VK. Hepatic NADH reductive stress underlies common variation in metabolic traits. Nature. 2020 07; 583(7814):122-126. PMID: 32461692; PMCID: PMC7536642.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  8. Luther J, Khan S, Gala MK, Kedrin D, Sridharan G, Goodman RP, Garber JJ, Masia R, Diagacomo E, Adams D, King KR, Piaker S, Reinecker HC, Yarmush ML, Argemi J, Bataller R, Dienstag JL, Chung RT, Patel SJ. Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11667-11673. PMID: 32393626.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  9. Patgiri A, Skinner OS, Miyazaki Y, Schleifer G, Marutani E, Shah H, Sharma R, Goodman RP, To TL, Robert Bao X, Ichinose F, Zapol WM, Mootha VK. An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance. Nat Biotechnol. 2020 03; 38(3):309-313. PMID: 31932725.
    Citations: 26     Fields:    Translation:HumansCells
  10. Luther J, Gala MK, Borren N, Masia R, Goodman RP, Moeller IH, DiGiacomo E, Ehrlich A, Warren A, Yarmush ML, Ananthakrishnan A, Corey K, Kaplan LM, Bhatia S, Chung RT, Patel SJ. Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity. Hepatol Commun. 2018 Jul; 2(7):786-797. PMID: 30202815; PMCID: PMC6123534.
    Citations: 6     Fields:    
  11. Goodman RP, Calvo SE, Mootha VK. Spatiotemporal compartmentalization of hepatic NADH and NADPH metabolism. J Biol Chem. 2018 05 18; 293(20):7508-7516. PMID: 29514978; PMCID: PMC5961030.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  12. Goodman RP, Chung DC. Clinical Genetic Testing in Gastroenterology. Clin Transl Gastroenterol. 2016 Apr 28; 7:e167. PMID: 27124700.
    Citations:    Fields:    
  13. Titov DV, Cracan V, Goodman RP, Peng J, Grabarek Z, Mootha VK. Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio. Science. 2016 Apr 08; 352(6282):231-5. PMID: 27124460; PMCID: PMC4850741.
    Citations: 109     Fields:    Translation:HumansCells
  14. Fichorova RN, Lee Y, Yamamoto HS, Takagi Y, Hayes GR, Goodman RP, Chepa-Lotrea X, Buck OR, Murray R, Kula T, Beach DH, Singh BN, Nibert ML. Endobiont viruses sensed by the human host - beyond conventional antiparasitic therapy. PLoS One. 2012; 7(11):e48418. PMID: 23144878.
    Citations: 60     Fields:    Translation:HumansAnimalsCells
  15. Yan X, Parent KN, Goodman RP, Tang J, Shou J, Nibert ML, Duncan R, Baker TS. Virion structure of baboon reovirus, a fusogenic orthoreovirus that lacks an adhesion fiber. J Virol. 2011 Aug; 85(15):7483-95. PMID: 21593159.
    Citations: 9     Fields:    Translation:AnimalsCells
  16. Goodman RP, Freret TS, Kula T, Geller AM, Talkington MW, Tang-Fernandez V, Suciu O, Demidenko AA, Ghabrial SA, Beach DH, Singh BN, Fichorova RN, Nibert ML. Clinical isolates of Trichomonas vaginalis concurrently infected by strains of up to four Trichomonasvirus species (Family Totiviridae). J Virol. 2011 May; 85(9):4258-70. PMID: 21345965.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  17. Goodman RP, Ghabrial SA, Fichorova RN, Nibert ML. Trichomonasvirus: a new genus of protozoan viruses in the family Totiviridae. Arch Virol. 2011 Jan; 156(1):171-9. PMID: 20976609.
    Citations: 35     Fields:    Translation:AnimalsCells
  18. Kato T, Goodman RP, Erben CM, Turberfield AJ, Namba K. High-resolution structural analysis of a DNA nanostructure by cryoEM. Nano Lett. 2009 Jul; 9(7):2747-50. PMID: 19492821.
    Citations: 22     Fields:    
  19. Goodman RP, Erben CM, Malo J, Ho WM, McKee ML, Kapanidis AN, Turberfield AJ. A facile method for reversibly linking a recombinant protein to DNA. Chembiochem. 2009 Jun 15; 10(9):1551-7. PMID: 19449345.
    Citations: 13     Fields:    Translation:Cells
  20. Goodman RP, Heilemann M, Doose S, Erben CM, Kapanidis AN, Turberfield AJ. Reconfigurable, braced, three-dimensional DNA nanostructures. Nat Nanotechnol. 2008 Feb; 3(2):93-6. PMID: 18654468.
    Citations: 65     Fields:    Translation:Cells
  21. Erben CM, Goodman RP, Turberfield AJ. A self-assembled DNA bipyramid. J Am Chem Soc. 2007 Jun 06; 129(22):6992-3. PMID: 17500526.
    Citations: 14     Fields:    Translation:Cells
  22. Erben CM, Goodman RP, Turberfield AJ. Single-molecule protein encapsulation in a rigid DNA cage. Angew Chem Int Ed Engl. 2006 Nov 13; 45(44):7414-7. PMID: 17086586.
    Citations: 52     Fields:    
  23. Goodman RP. NANEV: a program employing evolutionary methods for the design of nucleic acid nanostructures. Biotechniques. 2005 Apr; 38(4):548, 550. PMID: 15884672.
    Citations: 2     Fields:    Translation:Cells
  24. Goodman RP, Berry RM, Turberfield AJ. The single-step synthesis of a DNA tetrahedron. Chem Commun (Camb). 2004 Jun 21; (12):1372-3. PMID: 15179470.
    Citations: 67     Fields:    Translation:Cells
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© 2023 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.