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Mahmood, Umar
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Umar Mahmood, M.D., Ph.D.
Title
Professor of Radiology
Institution
Massachusetts General Hospital
Department
Radiology
Address
Massachusetts General Hospital
Martinos Center for Biomedical Imaging, Rm 2301
149 13th Street
Charlestown MA 02129
Phone
617/726-6477
Fax
617/726-7422
vCard
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login for email
)
webpage
|
completed student projects
|
research activities and funding
|
selected publications
|
Overview
webpage
Center for Precision Imaging
Mentoring
completed student projects
A Real-Time Method for Quantitative Catheter-Based Fluorescence Molecular Imaging
Summer, 06/01/05 - 09/01/05
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
R01DK123143
(MAHMOOD, UMAR)
Sep 4, 2020 - May 31, 2024
NIH
Granzyme B PET imaging as a marker of inflammatory bowel disease activity
Role: Principal Investigator
R01CA211223
(MAHMOOD, UMAR)
Dec 1, 2017 - Nov 30, 2022
NIH
Quantitative HER3 PET Imaging for Assessing Resistance and Guiding Therapy
Role: Principal Investigator
R01CA214744
(MAHMOOD, UMAR)
Aug 1, 2017 - Jul 31, 2022
NIH
Cytotoxic lymphocyte function PET imaging to predict cancer immunotherapy response
Role: Principal Investigator
U01CA202934
(MAHMOOD, UMAR)
Mar 2, 2017 - Jun 30, 2022
NIH
Optical and electromagnetic tracking guidance for hepatic interventions
Role: Principal Investigator
S10OD018004
(MAHMOOD, UMAR)
Apr 15, 2014 - Apr 14, 2016
NIH
MicroPET-MR scanner for preclinical molecular imaging
Role: Principal Investigator
R01CA166582
(MAHMOOD, UMAR)
Apr 1, 2013 - Mar 31, 2019
NIH
PET imaging of carcinoid tumors to guide individualized chemotherapy
Role: Principal Investigator
U01CA143056
(RUSTGI, ANIL K)
Sep 28, 2009 - Aug 31, 2014
NIH
Inflammation and the esophageal tumor microenvironment
Role: Principal Investigator
R01EB001872
(MAHMOOD, UMAR)
Sep 1, 2003 - Jul 31, 2008
NIH
In vivo multichannel fluorescent imaging
Role: Principal Investigator
U24CA092782
(WEISSLEDER, RALPH)
Jul 1, 2001 - Jun 30, 2013
NIH
Small Animal Imaging Resource
Role: Co-Principal Investigator
P50CA086355
(WEISSLEDER, RALPH)
Aug 9, 2000 - Jun 30, 2016
NIH
Center for Molecular Imaging Research at MGH/HMS
Role: Co-Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Langlotz CP, Mauro MA,
Mahmood U
, Klein JS, Meltzer CC, Bhalla S, Heller RE, Scott JA, Flanders AE, Pandharipande PV. Truth and Transformation: RSNA's Journey Toward Equity. Radiographics. 2023 04; 43(4):e239005.
PMID:
36862085
.
Citations:
Fields:
Rad
Radiology
Kuruppu D
, Bhere D,
Farrar CT
,
Shah K
,
Brownell AL
,
Mahmood U
,
Tanabe KK
. Correction to: Oncolytic HSV1 targets different growth phases of breast cancer leptomeningeal metastases. Cancer Gene Ther. 2023 Mar 08.
PMID:
36890212
.
Citations:
Fields:
Gen
Genetics
Neo
Neoplasms
The
Therapeutics
Langlotz CP, Mauro MA,
Mahmood U
, Klein JS, Meltzer CC, Bhalla S, Heller RE, Scott JA, Flanders AE, Pandharipande PV. Truth and Transformation: RSNA's Journey Toward Equity. Radiology. 2023 Mar 02; 239008.
PMID:
36862088
.
Citations:
Fields:
Rad
Radiology
Langlotz CP, Mauro MA,
Mahmood U
, Klein JS, Meltzer CC, Bhalla S, Heller RE, Scott JA, Flanders AE, Pandharipande PV. Truth and Transformation: RSNA's Journey Toward Equity. Radiol Imaging Cancer. 2023 Mar; 5(2):e239005.
PMID:
36862089
.
Citations:
Fields:
Neo
Neoplasms
Rad
Radiology
Shankar LK, Schöder H, Sharon E, Wolchok J, Knopp MV, Wahl RL, Ellingson BM, Hall NC, Yaffe MJ, Towbin AJ, Farwell MD, Pryma D,
Poussaint TY
, Wright CL, Schwartz L,
Harisinghani M
,
Mahmood U
, Wu AM, Leung D, de Vries EGE, Tang Y, Beach G, Reeves SA. Harnessing imaging tools to guide immunotherapy trials: summary from the National Cancer Institute Cancer Imaging Steering Committee workshop. Lancet Oncol. 2023 03; 24(3):e133-e143.
PMID:
36858729
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
O'Shea A
, Iravani A, Saboury B, Jadvar H,
Catalano O
,
Mahmood U
,
Heidari P
. Integrating Theranostics Into Patient Care Pathways: AJR Expert Panel Narrative Review. AJR Am J Roentgenol. 2023 Feb 22; 1-11.
PMID:
36321986
.
Citations:
Fields:
Rad
Radiology
Kuruppu D
, Bhere D,
Farrar CT
,
Shah K
,
Brownell AL
,
Mahmood U
,
Tanabe KK
. Oncolytic HSV1 targets different growth phases of breast cancer leptomeningeal metastases. Cancer Gene Ther. 2023 Feb 01.
PMID:
36721067
.
Citations:
Fields:
Gen
Genetics
Neo
Neoplasms
The
Therapeutics
Haj-Mirzaian A,
Mahmood U
,
Heidari P
. Targeted Molecular Imaging as a Biomarker in Urologic Oncology. Urol Clin North Am. 2023 Feb; 50(1):115-131.
PMID:
36424076
.
Citations:
Fields:
Uro
Urology
Translation:
Humans
Wang Y,
Yee A
, Bernstein Z,
O'Donnell E
,
Raje N
,
Mahmood U
. Carbon-11-Labeled Methionine PET/CT in Patients With FDG-Occult Multiple Myeloma: A Prospective Pilot Study. AJR Am J Roentgenol. 2023 Apr; 220(4):578-579.
PMID:
36382911
.
Citations:
Fields:
Rad
Radiology
Esfahani SA
, de Aguiar Ferreira C, Rotile NJ,
Ataeinia B
, Krishna S,
Catalano OA
,
Caravan P
, Yen YF,
Heidari P
,
Mahmood U
. HER3 PET Imaging Predicts Response to Pan Receptor Tyrosine Kinase Inhibition Therapy in Gastric Cancer. Mol Imaging Biol. 2023 Apr; 25(2):353-362.
PMID:
35962301
; PMCID:
PMC10024929
.
Citations:
1
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Mahmood UF
, Skinner GJ. Fifteen-minute consultation on excluding cardiac causes of chest pain. Arch Dis Child Educ Pract Ed. 2022 Aug 11.
PMID:
35953268
.
Citations:
Fields:
Ped
Pediatrics
de Aguiar Ferreira C,
Heidari P
,
Ataeinia B
, Sinevici N, Granito A, Kumar HM,
Wehrenberg-Klee E
,
Mahmood U
. Immune Checkpoint Inhibitor-Mediated Cancer Theranostics with Radiolabeled Anti-Granzyme B Peptide. Pharmaceutics. 2022 Jul 13; 14(7).
PMID:
35890355
; PMCID:
PMC9325142
.
Citations:
1
Esfahani SA
, Callahan C, Rotile NJ,
Heidari P
,
Mahmood U
,
Caravan PD
, Grant AK, Yen YF. Hyperpolarized [1-13C]Pyruvate Magnetic Resonance Spectroscopic Imaging for Evaluation of Early Response to Tyrosine Kinase Inhibition Therapy in Gastric Cancer. Mol Imaging Biol. 2022 10; 24(5):769-779.
PMID:
35467249
; PMCID:
PMC9588528
.
Citations:
1
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Translation:
Humans
Animals
Furtado FS, Wu MZ,
Esfahani SA
, Ferrone CR,
Blaszkowsky LS
,
Clark JW
,
Ryan DP
,
Goyal L
,
Franses JW
,
Wo JY
,
Hong TS
,
Qadan M
,
Tanabe KK
,
Weekes CD
,
Cusack JC
, Crafa F,
Mahmood U
,
Anderson MA
,
Mojtahed A
,
Hahn PF
,
Caravan P
,
Kilcoyne A
,
Vangel M
, Striar RM,
Rosen BR
,
Catalano OA
. Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) Versus the Standard of Care Imaging in the Diagnosis of Peritoneal Carcinomatosis. Ann Surg. 2023 04 01; 277(4):e893-e899.
PMID:
35185121
.
Citations:
1
Fields:
Gen
General Surgery
Ferreira CA,
Heidari P
,
Ataeinia B
, Sinevici N,
Sise ME
,
Colvin RB
,
Wehrenberg-Klee E
,
Mahmood U
. Non-invasive Detection of Immunotherapy-Induced Adverse Events. Clin Cancer Res. 2021 10 01; 27(19):5353-5364.
PMID:
34253581
; PMCID:
PMC8752648
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Zhang C,
O'Shea A
, Parente CA, Amorim BJ,
Caravan P
, Ferrone CR,
Blaszkowsky LS
, Soricelli A, Salvatore M, Groshar D, Bernstine H, Domachevsky L, Canamaque LG, Umutlu L, Ken H,
Catana C
,
Mahmood U
,
Catalano OA
. Evaluation of the Diagnostic Performance of Positron Emission Tomography/Magnetic Resonance for the Diagnosis of Liver Metastases. Invest Radiol. 2021 10 01; 56(10):621-628.
PMID:
33813576
.
Citations:
1
Fields:
Rad
Radiology
Translation:
Humans
Mahmood UF
, Durairaj S. Patent ductus arteriosus-related endocarditis: not just a theoretical risk. BMJ Case Rep. 2021 Jun 22; 14(6).
PMID:
34158324
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
Wehrenberg-Klee E
, Sinevici N, Nesti S, Kalomeris T, Austin E, Larimer B,
Mahmood U
. HER3 PET Imaging Identifies Dynamic Changes in HER3 in Response to HER2 Inhibition with Lapatinib. Mol Imaging Biol. 2021 12; 23(6):930-940.
PMID:
34101105
; PMCID:
PMC8578458
.
Citations:
2
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
de Ruiter QMB, Xu S, Li M, Pritchard WF, Starost MF, Filie A, Mikhail AS, Mauda-Havakuk M, Esparza-Trujillo JA, Bakhutashvili I,
Heidari P
,
Mahmood U
, Karanian JW, Wood BJ. Electromagnetic Tracking and Optical Molecular Imaging Guidance for Liver Biopsy and Point-of-Care Tissue Assessment in Phantom and Woodchuck Hepatocellular Carcinoma. Cardiovasc Intervent Radiol. 2021 Sep; 44(9):1439-1447.
PMID:
34021380
; PMCID:
PMC8384721
.
Citations:
Fields:
Car
Cardiology
Rad
Radiology
Vas
Vascular Diseases
Translation:
Animals
Husseini JS
, Amorim BJ, Torrado-Carvajal A, Prabhu V, Groshar D, Umutlu L, Herrmann K, Cañamaque LG, Garzón JRG,
Palmer WE
,
Heidari P
, Shih TT, Sosna J, Matushita C, Cerci J, Queiroz M, Muglia VF, Nogueira-Barbosa MH, Borra RJH, Kwee TC, Glaudemans AWJM, Evangelista L, Salvatore M, Cuocolo A, Soricelli A, Herold C, Laghi A, Mayerhoefer M,
Mahmood U
,
Catana C
, Daldrup-Link HE,
Rosen B
,
Catalano OA
. An international expert opinion statement on the utility of PET/MR for imaging of skeletal metastases. Eur J Nucl Med Mol Imaging. 2021 05; 48(5):1522-1537.
PMID:
33619599
; PMCID:
PMC8240455
.
Citations:
1
Fields:
Nuc
Nuclear Medicine
Phy
Physics
Translation:
Humans
Biondetti P,
Vangel MG
,
Lahoud RM
, Furtado FS,
Rosen BR
, Groshar D, Canamaque LG, Umutlu L, Zhang EW,
Mahmood U
,
Digumarthy SR
, Shepard JO,
Catalano OA
. PET/MRI assessment of lung nodules in primary abdominal malignancies: sensitivity and outcome analysis. Eur J Nucl Med Mol Imaging. 2021 06; 48(6):1976-1986.
PMID:
33415433
.
Citations:
6
Fields:
Nuc
Nuclear Medicine
Phy
Physics
Translation:
Humans
Tan BS, Dunnick NR, Gangi A, Goergen S, Jin ZY, Neri E, Nomura CH, Pitcher RD, Yee J,
Mahmood U
. RSNA International Trends: A Global Perspective on the COVID-19 Pandemic and Radiology in Late 2020. Radiology. 2021 04; 299(1):E193-E203.
PMID:
33289616
; PMCID:
PMC7734846
.
Citations:
15
Fields:
Rad
Radiology
Translation:
Humans
Cells
PH
Public Health
Sinevici N,
Ataeinia B
, Zehnder V, Lin K, Grove L,
Heidari P
,
Mahmood U
. HER3 Differentiates Basal From Claudin Type Triple Negative Breast Cancer and Contributes to Drug and Microenvironmental Induced Resistance. Front Oncol. 2020; 10:554704.
PMID:
33330026
.
Citations:
4
Silva CF, Elizondo-Rojas G, Atalabi O, Karçaaltincaba M, Morana G,
Mahmood U
. RSNA Committee on International Radiology Education: 25 Years of Global Education Outreach. Radiographics. 2020 Nov-Dec; 40(7):1938-1952.
PMID:
33136478
.
Citations:
Fields:
Rad
Radiology
Translation:
Humans
Catalano OA
,
Lee SI
, Parente C,
Cauley C
, Furtado FS, Striar R, Soricelli A, Salvatore M, Li Y, Umutlu L, Cañamaque LG, Groshar D,
Mahmood U
,
Blaszkowsky LS
,
Ryan DP
,
Clark JW
,
Wo J
,
Hong TS
,
Kunitake H
,
Bordeianou L
,
Berger D
,
Ricciardi R
,
Rosen B
. Improving staging of rectal cancer in the pelvis: the role of PET/MRI. Eur J Nucl Med Mol Imaging. 2021 04; 48(4):1235-1245.
PMID:
33034673
.
Citations:
15
Fields:
Nuc
Nuclear Medicine
Phy
Physics
Translation:
Humans
Xu J, Higgins MJ,
Tolaney SM
,
Come SE
, Smith MR, Fornier M,
Mahmood U
, Baselga J,
Yeap BY
,
Chabner BA
,
Isakoff SJ
. A Phase II Trial of Cabozantinib in Hormone Receptor-Positive Breast Cancer with Bone Metastases. Oncologist. 2020 08; 25(8):652-660.
PMID:
32463152
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
LaSalle T, Austin EE, Rigney G,
Wehrenberg-Klee E
, Nesti S, Larimer B,
Mahmood U
. Granzyme B PET imaging of immune-mediated tumor killing as a tool for understanding immunotherapy response. J Immunother Cancer. 2020 05; 8(1).
PMID:
32461343
.
Citations:
13
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Tam J
, Pilozzi A,
Mahmood U
,
Huang X
. Simultaneous Monitoring of Multi-Enzyme Activity and Concentration in Tumor Using a Triply Labeled Fluorescent In Vivo Imaging Probe. Int J Mol Sci. 2020 Apr 27; 21(9).
PMID:
32349205
.
Citations:
2
Fields:
Bio
Biochemistry
Che
Chemistry
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Ferrone C,
Goyal L
,
Qadan M
,
Gervais D
, Sahani DV, Zhu AX,
Hong TS
,
Blaszkowsky LS
,
Tanabe KK
,
Vangel M
, Amorim BJ,
Wo JY
,
Mahmood U
, Pandharipande PV,
Catana C
, Duenas VP, Collazo YQ, Canamaque LG, Domachevsky L, Bernstine HH, Groshar D, Shih TT, Li Y, Herrmann K, Umutlu L,
Rosen BR
,
Catalano OA
. Management implications of fluorodeoxyglucose positron emission tomography/magnetic resonance in untreated intrahepatic cholangiocarcinoma. Eur J Nucl Med Mol Imaging. 2020 07; 47(8):1871-1884.
PMID:
31705172
.
Citations:
10
Fields:
Nuc
Nuclear Medicine
Phy
Physics
Translation:
Humans
Esfahani SA
,
Heidari P
,
Kucherlapati MH
, Ferrer JM,
Kucherlapati RS
,
Mahmood U
. Optical imaging with a novel cathepsin-activatable probe for enhanced detection of colorectal cancer. Am J Nucl Med Mol Imaging. 2019; 9(5):230-242.
PMID:
31772821
; PMCID:
PMC6872479
.
Citations:
6
Amorim BJ,
Hong TS
,
Blaszkowsky LS
, Ferrone CR,
Berger DL
,
Bordeianou LG
,
Ricciardi R
,
Clark JW
,
Ryan DP
,
Wo JY
,
Qadan M
,
Vangel M
, Umutlu L, Groshar D, Cañamaques LG,
Gervais DA
,
Mahmood U
,
Rosen BR
,
Catalano OA
. Clinical impact of PET/MR in treated colorectal cancer patients. Eur J Nucl Med Mol Imaging. 2019 Oct; 46(11):2260-2269.
PMID:
31359108
.
Citations:
13
Fields:
Nuc
Nuclear Medicine
Phy
Physics
Translation:
Humans
Gilbert TM, Zürcher NR,
Catanese MC
,
Tseng CJ
, Di Biase MA,
Lyall AE
, Hightower BG, Parmar AJ, Bhanot A, Wu CJ, Hibert ML, Kim M,
Mahmood U
,
Stufflebeam SM
, Schroeder FA, Wang C,
Roffman JL
,
Holt DJ
,
Greve DN
,
Pasternak O
,
Kubicki M
,
Wey HY
,
Hooker JM
. Neuroepigenetic signatures of age and sex in the living human brain. Nat Commun. 2019 07 03; 10(1):2945.
PMID:
31270332
.
Citations:
14
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Wang Y, Ayres KL, Goldman DA, Dickler MN,
Bardia A
, Mayer IA, Winer E, Fredrickson J, Arteaga CL, Baselga J, Manning HC,
Mahmood U
, Ulaner GA. Correction: 18F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials. Clin Cancer Res. 2019 Feb 15; 25(4):1435.
PMID:
30770494
.
Citations:
1
Fields:
Neo
Neoplasms
Andriole GL, Kostakoglu L, Chau A, Duan F,
Mahmood U
, Mankoff DA, Schuster DM, Siegel BA. The Impact of Positron Emission Tomography with 18F-Fluciclovine on the Treatment of Biochemical Recurrence of Prostate Cancer: Results from the LOCATE Trial. J Urol. 2019 02; 201(2):322-331.
PMID:
30179618
; PMCID:
PMC7007765
.
Citations:
41
Fields:
Uro
Urology
Translation:
Humans
CT
Clinical Trials
Zadra G, Ribeiro CF,
Chetta P
, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y,
Tyekucheva S
, Bastos DC, Tchaicha J,
Lawney B
, Uo T, D'Anello L, Csibi A, Kalekar R, Larimer B, Ellis L, Butler LM, Morrissey C, McGovern K, Palombella VJ, Kutok JL,
Mahmood U
, Bosari S, Adams J, Peluso S, Dehm SM, Plymate SR,
Loda M
. Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2019 01 08; 116(2):631-640.
PMID:
30578319
; PMCID:
PMC6329966
.
Citations:
103
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Larimer BM, Bloch E, Nesti S, Austin EE,
Wehrenberg-Klee E
,
Boland G
,
Mahmood U
. The Effectiveness of Checkpoint Inhibitor Combinations and Administration Timing Can Be Measured by Granzyme B PET Imaging. Clin Cancer Res. 2019 02 15; 25(4):1196-1205.
PMID:
30327313
; PMCID:
PMC6377844
.
Citations:
44
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Ferry-Galow KV, Datta V, Makhlouf HR, Wright J, Wood BJ, Levy E, Pisano ED, Tam AL,
Lee SI
,
Mahmood U
, Rubinstein LV, Doroshow JH, Chen AP. What Can Be Done to Improve Research Biopsy Quality in Oncology Clinical Trials? J Oncol Pract. 2018 Oct 04; JOP1800092.
PMID:
30285529
.
Citations:
18
Fields:
Neo
Neoplasms
Catalano O
,
Kilcoyne A
, Signore A,
Mahmood U
,
Rosen B
. Lower Gastrointestinal Tract Applications of PET/Computed Tomography and PET/MR Imaging. Radiol Clin North Am. 2018 Sep; 56(5):821-834.
PMID:
30119776
.
Citations:
3
Fields:
Rad
Radiology
Translation:
Humans
Hanna GJ, Supplee JG, Kuang Y,
Mahmood U
, Lau CJ,
Haddad RI
, Jänne PA, Paweletz CP. Plasma HPV cell-free DNA monitoring in advanced HPV-associated oropharyngeal cancer. Ann Oncol. 2018 09 01; 29(9):1980-1986.
PMID:
30010779
.
Citations:
35
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Catalano OA
, Umutlu L, Fuin N, Hibert ML,
Scipioni M
, Pedemonte S,
Vangel M
,
Catana AM
, Herrmann K, Nensa F, Groshar D,
Mahmood U
,
Rosen BR
,
Catana C
. Comparison of the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo). Eur J Nucl Med Mol Imaging. 2018 11; 45(12):2147-2154.
PMID:
29998420
.
Citations:
5
Fields:
Nuc
Nuclear Medicine
Phy
Physics
Translation:
Humans
Wang Y,
Rapalino O
,
Heidari P
,
Loeffler J
,
Shih HA
,
Oh K
,
Mahmood U
. C11 Methionine PET (MET-PET) Imaging of Glioblastoma for Detecting Postoperative Residual Disease and Response to Chemoradiation Therapy. Int J Radiat Oncol Biol Phys. 2018 11 15; 102(4):1024-1028.
PMID:
29913253
; PMCID:
PMC7336810
.
Citations:
6
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
CT
Clinical Trials
Larimer BM, Dubois F, Bloch E, Nesti S, Placzek M, Zadra G,
Hooker JM
,
Loda M
,
Mahmood U
. Specific 18F-FDHT Accumulation in Human Prostate Cancer Xenograft Murine Models Is Facilitated by Prebinding to Sex Hormone-Binding Globulin. J Nucl Med. 2018 10; 59(10):1538-1543.
PMID:
29853654
.
Citations:
2
Fields:
Nuc
Nuclear Medicine
Translation:
Humans
Animals
Cells
Heidari P
, Kunawudhi A, Martinez-Quintanilla J, Szretter A,
Shah K
,
Mahmood U
. Somatostatin receptor type 2 as a radiotheranostic PET reporter gene for oncologic interventions. Theranostics. 2018; 8(12):3380-3391.
PMID:
29930736
.
Citations:
9
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Nan
Nanotechnology
The
Therapeutics
Translation:
Humans
Animals
Cells
Li Q
, Xiang F, Lin X, Grajo JR, Yang L, Xu Y, Duan Y, Vyas U,
Harisinghani M
,
Mahmood U
,
Samir AE
. The Role of Imaging in Prostate Cancer Care Pathway: Novel Approaches to Urologic Management Challenges Along 10 Imaging Touch Points. Urology. 2018 Sep; 119:23-31.
PMID:
29730256
.
Citations:
3
Fields:
Uro
Urology
Translation:
Humans
Larimer BM, Phelan N,
Wehrenberg-Klee E
,
Mahmood U
. Phage Display Selection, In Vitro Characterization, and Correlative PET Imaging of a Novel HER3 Peptide. Mol Imaging Biol. 2018 04; 20(2):300-308.
PMID:
28733706
.
Citations:
9
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Translation:
Animals
Cells
Catalano OA
,
Wu V
,
Mahmood U
, Signore A,
Vangel M
, Soricelli A, Salvatore M,
Gervais D
,
Rosen BR
. Diagnostic performance of PET/MR in the evaluation of active inflammation in Crohn disease. Am J Nucl Med Mol Imaging. 2018; 8(1):62-69.
PMID:
29531862
; PMCID:
PMC5840324
.
Citations:
10
Jadvar H, Chen X, Cai W,
Mahmood U
. Radiotheranostics in Cancer Diagnosis and Management. Radiology. 2018 02; 286(2):388-400.
PMID:
29356634
; PMCID:
PMC5790308
.
Citations:
29
Fields:
Rad
Radiology
Translation:
Humans
Wang Y,
Yee AJ
, Sirard C, Landau S,
Raje N
,
Mahmood U
. Sodium fluoride PET imaging as a quantitative pharmacodynamic biomarker for bone homeostasis during anti-DKK1 therapy for multiple myeloma. Blood Cancer J. 2017 10 06; 7(10):e615.
PMID:
28984867
.
Citations:
4
Fields:
All
Allergy and Immunology
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Collier TL,
Normandin MD
, Stephenson NA, Livni E,
Liang SH
,
Wooten DW
,
Esfahani SA
, Stabin MG,
Mahmood U
, Chen J, Wang W, Maresca K, Waterhouse RN,
El Fakhri G
,
Richardson P
, Vasdev N. Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib. Nat Commun. 2017 06 08; 8:15761.
PMID:
28594000
; PMCID:
PMC5472746
.
Citations:
19
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Catalano OA
,
Daye D
, Signore A, Iannace C,
Vangel M
, Luongo A, Catalano M, Filomena M, Mansi L, Soricelli A, Salvatore M, Fuin N,
Catana C
,
Mahmood U
,
Rosen BR
. Staging performance of whole-body DWI, PET/CT and PET/MRI in invasive ductal carcinoma of the breast. Int J Oncol. 2017 Jul; 51(1):281-288.
PMID:
28535000
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
Holliday EB, Kuban DA, Levy LB, Bolukbasi Y, Master P, Choi S, Nguyen Q, McGuire SE,
Mahmood U
, Frank SJ, Hoffman KE. Select men benefit from androgen deprivation therapy delivered with salvage radiation therapy after prostatectomy. Prostate Cancer Prostatic Dis. 2017 12; 20(4):389-394.
PMID:
28462945
.
Citations:
1
Fields:
Neo
Neoplasms
Uro
Urology
Translation:
Humans
Larimer BM,
Wehrenberg-Klee E
, Dubois F, Mehta A, Kalomeris T,
Flaherty K
,
Boland G
,
Mahmood U
. Granzyme B PET Imaging as a Predictive Biomarker of Immunotherapy Response. Cancer Res. 2017 05 01; 77(9):2318-2327.
PMID:
28461564
; PMCID:
PMC5474226
.
Citations:
127
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Esfahani SA
, Salcedo S,
Heidari P
,
Catalano OA
, Pauplis R, Hesterman J, Kronauge JF,
Mahmood U
. A phase one, single-dose, open-label, clinical safety and PET/MR imaging study of 68Ga-DOTATOC in healthy volunteers. Am J Nucl Med Mol Imaging. 2017; 7(2):53-62.
PMID:
28533937
; PMCID:
PMC5435611
.
Citations:
3
Catalano OA
, Coutinho AM, Sahani DV,
Vangel MG
,
Gee MS
,
Hahn PF
, Witzel T, Soricelli A, Salvatore M,
Catana C
,
Mahmood U
,
Rosen BR
,
Gervais D
. Colorectal cancer staging: comparison of whole-body PET/CT and PET/MR. Abdom Radiol (NY). 2017 04; 42(4):1141-1151.
PMID:
27891551
.
Citations:
15
Fields:
Dia
Diagnostic Imaging
Gas
Gastroenterology
Translation:
Humans
Catalano OA
, Horn GL, Signore A, Iannace C, Lepore M,
Vangel M
, Luongo A, Catalano M,
Lehman C
, Salvatore M, Soricelli A,
Catana C
,
Mahmood U
,
Rosen BR
. PET/MR in invasive ductal breast cancer: correlation between imaging markers and histological phenotype. Br J Cancer. 2017 Mar 28; 116(7):893-902.
PMID:
28208155
; PMCID:
PMC5379139
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Catalano OA
, Masch WR,
Catana C
,
Mahmood U
, Sahani DV,
Gee MS
, Menezes L, Soricelli A, Salvatore M,
Gervais D
,
Rosen BR
. An overview of PET/MR, focused on clinical applications. Abdom Radiol (NY). 2017 02; 42(2):631-644.
PMID:
27624499
.
Citations:
6
Fields:
Dia
Diagnostic Imaging
Gas
Gastroenterology
Translation:
Humans
Wang Y, Ayres KL, Goldman DA, Dickler MN,
Bardia A
, Mayer IA, Winer E, Fredrickson J, Arteaga CL, Baselga J, Manning HC,
Mahmood U
, Ulaner GA. 18F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials. Clin Cancer Res. 2017 Jun 15; 23(12):3053-3060.
PMID:
28011460
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Qian ZR, Li T, Ter-Minassian M, Yang J,
Chan JA
, Brais LK, Masugi Y, Thiaglingam A, Brooks N, Nishihara R, Bonnemarie M, Masuda A, Inamura K, Kim SA, Mima K, Sukawa Y, Dou R,
Lin X
,
Christiani DC
, Schmidlin F, Fuchs CS,
Mahmood U
,
Ogino S
, Kulke MH. Association Between Somatostatin Receptor Expression and Clinical Outcomes in Neuroendocrine Tumors. Pancreas. 2016 11; 45(10):1386-1393.
PMID:
27622342
.
Citations:
48
Fields:
Gas
Gastroenterology
Translation:
Humans
Kilcoyne A
,
Harisinghani MG
,
Mahmood U
. Prostate Cancer Imaging and Therapy: Potential Role of Nanoparticles. J Nucl Med. 2016 Oct; 57(Suppl 3):105S-110S.
PMID:
27694162
.
Citations:
2
Fields:
Nuc
Nuclear Medicine
Translation:
Humans
Animals
Wang Y, Oh KS, Loeffler JS, Shih HA,
Mahmood U
. C11 Methionine Positron Emission Tomography (MET-PET) Imaging of Glioblastoma for Detecting Postoperative Residual Disease and Response to Chemoradiation Therapy. Int J Radiat Oncol Biol Phys. 2016 Oct 1; 96(2S):E93.
PMID:
27675505
.
Citations:
Esfahani SA
,
Heidari P
, Kim SA,
Ogino S
,
Mahmood U
. Optical Imaging of Mesenchymal Epithelial Transition Factor (MET) for Enhanced Detection and Characterization of Primary and Metastatic Hepatic Tumors. Theranostics. 2016; 6(12):2028-2038.
PMID:
27698938
.
Citations:
5
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Nan
Nanotechnology
The
Therapeutics
Translation:
Humans
Animals
Cells
Heidari P
, Szretter A, Rushford LE, Stevens M, Collier L, Sore J,
Hooker J
,
Mahmood U
. Design, construction and testing of a low-cost automated (68)Gallium-labeling synthesis unit for clinical use. Am J Nucl Med Mol Imaging. 2016; 6(3):176-84.
PMID:
27508104
; PMCID:
PMC4965522
.
Citations:
4
Larimer BM,
Wehrenberg-Klee E
, Caraballo A,
Mahmood U
. Quantitative CD3 PET Imaging Predicts Tumor Growth Response to Anti-CTLA-4 Therapy. J Nucl Med. 2016 Oct; 57(10):1607-1611.
PMID:
27230929
; PMCID:
PMC5367446
.
Citations:
62
Fields:
Nuc
Nuclear Medicine
Translation:
Animals
Cells
McPartlin AJ, Li XA, Kershaw LE, Heide U, Kerkmeijer L, Lawton C,
Mahmood U
, Pos F, van As N, van Herk M, Vesprini D, van der Voort van Zyp J, Tree A, Choudhury A. MRI-guided prostate adaptive radiotherapy - A systematic review. Radiother Oncol. 2016 06; 119(3):371-80.
PMID:
27162159
.
Citations:
49
Fields:
Neo
Neoplasms
Rad
Radiotherapy
Translation:
Humans
Wehrenberg-Klee E
, Turker NS,
Heidari P
, Larimer B,
Juric D
, Baselga J, Scaltriti M,
Mahmood U
. Differential Receptor Tyrosine Kinase PET Imaging for Therapeutic Guidance. J Nucl Med. 2016 09; 57(9):1413-9.
PMID:
27081168
; PMCID:
PMC5093919
.
Citations:
17
Fields:
Nuc
Nuclear Medicine
Translation:
Humans
Cells
Pugmire BS, Guimaraes AR,
Lim R
,
Friedmann AM
, Huang M,
Ebb D
,
Weinstein H
,
Catalano OA
,
Mahmood U
,
Catana C
,
Gee MS
. Simultaneous whole body (18)F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging for evaluation of pediatric cancer: Preliminary experience and comparison with (18)F-fluorodeoxyglucose positron emission tomography computed tomography. World J Radiol. 2016 Mar 28; 8(3):322-30.
PMID:
27028112
; PMCID:
PMC4807342
.
Citations:
2
Sheth RA,
Heidari P
, Woods K,
Chung D
,
Chan AT
,
Mahmood U
. Pilot Clinical Trial of Indocyanine Green Fluorescence-Augmented Colonoscopy in High Risk Patients. Gastroenterol Res Pract. 2016; 2016:6184842.
PMID:
26989406
; PMCID:
PMC4773548
.
Citations:
2
Kunawudhi A,
Wong AK
,
Alkasab TK
,
Mahmood U
. Accuracy of FDG-PET/CT for Detection of Incidental Pre-Malignant and Malignant Colonic Lesions - Correlation with Colonoscopic and Histopathologic Findings. Asian Pac J Cancer Prev. 2016; 17(8):4143-7.
PMID:
27644675
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P,
Heidari P
,
Mahmood U
, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 2015 Dec 14; 28(6):831-833.
PMID:
28843279
.
Citations:
83
Fields:
Neo
Neoplasms
Mahmood U
. 2015 SNMMI Highlights Lecture: Oncology, Part II. J Nucl Med. 2015 Dec; 56(12):9N-16N.
PMID:
26626870
.
Citations:
Fields:
Nuc
Nuclear Medicine
Translation:
Humans
Animals
Mahmood U
. 2015 SNMMI Highlights Lecture: Oncology, Part I. J Nucl Med. 2015 Nov; 56(11):9N-16N.
PMID:
26526798
; PMCID:
PMC4826777
.
Citations:
Fields:
Nuc
Nuclear Medicine
Translation:
Humans
Animals
Wehrenberg-Klee E
, Redjal N, Leece A, Turker NS,
Heidari P
,
Shah K
,
Mahmood U
. PET imaging of glioblastoma multiforme EGFR expression for therapeutic decision guidance. Am J Nucl Med Mol Imaging. 2015; 5(4):379-89.
PMID:
26269775
; PMCID:
PMC4529591
.
Citations:
8
Heidari P
,
Esfahani SA
, Turker NS, Wong G, Wang TC, Rustgi AK,
Mahmood U
. Imaging of Secreted Extracellular Periostin, an Important Marker of Invasion in the Tumor Microenvironment in Esophageal Cancer. J Nucl Med. 2015 Aug; 56(8):1246-51.
PMID:
26069303
; PMCID:
PMC4826779
.
Citations:
11
Fields:
Nuc
Nuclear Medicine
Translation:
Humans
Animals
Cells
Catalano OA
, Nicolai E,
Rosen BR
, Luongo A, Catalano M, Iannace C, Guimaraes A,
Vangel MG
,
Mahmood U
, Soricelli A, Salvatore M. Comparison of CE-FDG-PET/CT with CE-FDG-PET/MR in the evaluation of osseous metastases in breast cancer patients. Br J Cancer. 2015 Apr 28; 112(9):1452-60.
PMID:
25871331
; PMCID:
PMC4453670
.
Citations:
38
Fields:
Neo
Neoplasms
Translation:
Humans
Arvold ND,
Heidari P
, Kunawudhi A,
Sequist LV
,
Mahmood U
. Tumor Hypoxia Response After Targeted Therapy in EGFR-Mutant Non-Small Cell Lung Cancer: Proof of Concept for FMISO-PET. Technol Cancer Res Treat. 2016 Apr; 15(2):234-42.
PMID:
25759424
; PMCID:
PMC4565779
.
Citations:
7
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Leahy AA,
Esfahani SA
, Foote AT, Hui CK, Rainbow RS, Nakamura DS, Tracey BH,
Mahmood U
, Zeng L. Analysis of the trajectory of osteoarthritis development in a mouse model by serial near-infrared fluorescence imaging of matrix metalloproteinase activities. Arthritis Rheumatol. 2015 Feb; 67(2):442-53.
PMID:
25385707
; PMCID:
PMC4312249
.
Citations:
13
Fields:
Rhe
Rheumatology
Translation:
Animals
Cells
Heidari P
, Deng F,
Esfahani SA
, Leece AK,
Shoup TM
, Vasdev N,
Mahmood U
. Pharmacodynamic imaging guides dosing of a selective estrogen receptor degrader. Clin Cancer Res. 2015 Mar 15; 21(6):1340-7.
PMID:
25609068
; PMCID:
PMC4359957
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Gupta S,
Mahmood U
, Gurung S, Shrestha S, Kushner AL, Nwomeh BC, Charles AG. Burns in Nepal: A population based national assessment. Burns. 2015 Aug; 41(5):1126-32.
PMID:
25523087
.
Citations:
13
Fields:
Tra
Traumatology
Translation:
Humans
Mahmood U
. 2014 SNMMI highlights lecture: Oncology. J Nucl Med. 2014 Nov; 55(11):9N-24N.
PMID:
25368337
; PMCID:
PMC4403671
.
Citations:
1
Fields:
Nuc
Nuclear Medicine
Translation:
Humans
Animals
Cells
Sheth RA,
Arellano RS
,
Uppot RN
,
Samir AE
,
Goyal L
, Zhu AX,
Gervais DA
,
Mahmood U
. Prospective trial with optical molecular imaging for percutaneous interventions in focal hepatic lesions. Radiology. 2015 Mar; 274(3):917-26.
PMID:
25302707
; PMCID:
PMC4407559
.
Citations:
18
Fields:
Rad
Radiology
Translation:
Humans
CT
Clinical Trials
Zadra G, Photopoulos C,
Tyekucheva S
,
Heidari P
, Weng QP, Fedele G, Liu H, Scaglia N,
Priolo C
,
Sicinska E
,
Mahmood U
,
Signoretti S
, Birnberg N,
Loda M
. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014; 6(10):1357.
PMID:
25178544
.
Citations:
Stangenberg L
, Burzyn D, Binstadt BA,
Weissleder R
,
Mahmood U
,
Benoist C
,
Mathis D
. Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):11419-24.
PMID:
25049388
.
Citations:
29
Fields:
Sci
Science
Translation:
Animals
Cells
Turker NS,
Heidari P
,
Kucherlapati R
,
Kucherlapati M
,
Mahmood U
. An EGFR targeted PET imaging probe for the detection of colonic adenocarcinomas in the setting of colitis. Theranostics. 2014; 4(9):893-903.
PMID:
25057314
.
Citations:
20
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Nan
Nanotechnology
The
Therapeutics
Translation:
Humans
Animals
Cells
Kuruppu D
,
Brownell AL
,
Shah K
,
Mahmood U
,
Tanabe KK
. Molecular imaging with bioluminescence and PET reveals viral oncolysis kinetics and tumor viability. Cancer Res. 2014 Aug 01; 74(15):4111-21.
PMID:
24876106
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P,
Heidari P
,
Mahmood U
, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014 Jun 16; 25(6):719-34.
PMID:
24856586
; PMCID:
PMC4180632
.
Citations:
1065
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Habibollahi P, Waldron T,
Heidari P
, Cho HS, Alcantara D,
Josephson L
, Wang TC, Rustgi AK,
Mahmood U
. Fluorescent Nanoparticle Imaging Allows Noninvasive Evaluation of Immune Cell Modulation in Esophageal Dysplasia. Mol Imaging. 2014 May 01; 13(3):7290201400003.
PMID:
28650303
.
Citations:
Sheth RA,
Heidari P
,
Esfahani SA
, Wood BJ,
Mahmood U
. Interventional optical molecular imaging guidance during percutaneous biopsy. Radiology. 2014 Jun; 271(3):770-7.
PMID:
24520946
; PMCID:
PMC4263633
.
Citations:
16
Fields:
Rad
Radiology
Translation:
Animals
Zadra G, Photopoulos C,
Tyekucheva S
,
Heidari P
, Weng QP, Fedele G, Liu H, Scaglia N,
Priolo C
,
Sicinska E
,
Mahmood U
,
Signoretti S
, Birnberg N,
Loda M
. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014 04; 6(4):519-38.
PMID:
24497570
.
Citations:
99
Fields:
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Habibollahi P, Waldron T,
Heidari P
, Cho HS, Alcantara D,
Josephson L
, Wang TC, Rustgi AK,
Mahmood U
. Fluorescent nanoparticle imaging allows noninvasive evaluation of immune cell modulation in esophageal dysplasia. Mol Imaging. 2014; 13:1-11.
PMID:
24824854
.
Citations:
5
Fields:
Dia
Diagnostic Imaging
Translation:
Animals
Cells
Heidari P
,
Wehrenberg-Klee E
, Habibollahi P,
Yokell D
, Kulke M,
Mahmood U
. Free somatostatin receptor fraction predicts the antiproliferative effect of octreotide in a neuroendocrine tumor model: implications for dose optimization. Cancer Res. 2013 Dec 01; 73(23):6865-73.
PMID:
24080280
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Martinez-Quintanilla J, Bhere D,
Heidari P
, He D,
Mahmood U
,
Shah K
. Therapeutic efficacy and fate of bimodal engineered stem cells in malignant brain tumors. Stem Cells. 2013 Aug; 31(8):1706-14.
PMID:
23389839
.
Citations:
48
Fields:
Cel
Cell Biology
Emb
Embryology
Translation:
Humans
Animals
Cells
Kucherlapati MH
,
Esfahani S
, Habibollahi P, Wang J, Still ER,
Bronson RT
,
Mahmood U
,
Kucherlapati RS
. Genotype directed therapy in murine mismatch repair deficient tumors. PLoS One. 2013; 8(7):e68817.
PMID:
23935891
; PMCID:
PMC3720855
.
Citations:
5
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Leece AK,
Heidari P
,
Yokell DL
,
Mahmood U
. A container closure system that allows for greater recovery of radiolabeled peptide compared to the standard borosilicate glass system. Appl Radiat Isot. 2013 Oct; 80:99-102.
PMID:
23860127
.
Citations:
4
Fields:
Env
Environmental Health
Nuc
Nuclear Medicine
Esfahani SA
,
Heidari P
, Halpern EF,
Hochberg EP
, Palmer EL,
Mahmood U
. Baseline total lesion glycolysis measured with (18)F-FDG PET/CT as a predictor of progression-free survival in diffuse large B-cell lymphoma: a pilot study. Am J Nucl Med Mol Imaging. 2013; 3(3):272-81.
PMID:
23638338
.
Citations:
37
Martin ES, Belmont PJ, Sinnamon MJ, Richard LG, Yuan J, Coffee EM, Roper J, Lee L,
Heidari P
, Lunt SY, Goel G, Ji X, Xie Z, Xie T, Lamb J, Weinrich SL, VanArsdale T,
Bronson RT
,
Xavier RJ
,
Vander Heiden MG
, Kan JL,
Mahmood U
, Hung KE. Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation. Clin Cancer Res. 2013 Jun 01; 19(11):2929-40.
PMID:
23403635
; PMCID:
PMC3951107
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Cho H, Alcantara D,
Yuan H
, Sheth RA, Chen HH, Huang P, Andersson SB,
Sosnovik DE
,
Mahmood U
,
Josephson L
. Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems. ACS Nano. 2013 Mar 26; 7(3):2032-41.
PMID:
23373524
.
Citations:
8
Fields:
Nan
Nanotechnology
Translation:
Humans
Animals
Cells
Habibollahi P, van den Berg NS,
Kuruppu D
,
Loda M
,
Mahmood U
. Metformin--an adjunct antineoplastic therapy--divergently modulates tumor metabolism and proliferation, interfering with early response prediction by 18F-FDG PET imaging. J Nucl Med. 2013 Feb; 54(2):252-8.
PMID:
23376854
.
Citations:
14
Fields:
Nuc
Nuclear Medicine
Translation:
Humans
Animals
Cells
Wong GS, Habibollahi P,
Heidari P
, Lee JS, Klein-Szanto AJ, Waldron TJ, Gimotty P, Nakagawa H, Taylor PR, Wang TC,
Mahmood U
, Rustgi AK. Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice. Gastroenterology. 2013 Feb; 144(2):294-297.
PMID:
23085486
; PMCID:
PMC3624041
.
Citations:
13
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Saylor PJ
,
Mahmood U
, Kunawudhi A,
Smith MR
, Palmer EL,
Michaelson MD
. Multitargeted tyrosine kinase inhibition produces discordant changes between 99mTc-MDP bone scans and other disease biomarkers: analysis of a phase II study of sunitinib for metastatic castration-resistant prostate cancer. J Nucl Med. 2012 Nov; 53(11):1670-5.
PMID:
22984218
.
Citations:
7
Fields:
Nuc
Nuclear Medicine
Translation:
Humans
CT
Clinical Trials
Sheth RA, Kunin A,
Stangenberg L
, Sinnamon M, Hung KE,
Kucherlapati R
,
Mahmood U
. In vivo optical molecular imaging of matrix metalloproteinase activity following celecoxib therapy for colorectal cancer. Mol Imaging. 2012 Sep-Oct; 11(5):417-25.
PMID:
22954186
.
Citations:
6
Fields:
Dia
Diagnostic Imaging
Translation:
Humans
Animals
Cells
Yokell DL
, Leece AK, Lebedev A, Miraghaie R, Ball CE, Zhang J, Kolb H, Elizarov A,
Mahmood U
. Microfluidic single vessel production of hypoxia tracer 1H-1-(3-[18F]-fluoro-2-hydroxy-propyl)-2-nitro-imidazole ([18F]-FMISO). Appl Radiat Isot. 2012 Oct; 70(10):2313-6.
PMID:
22871433
.
Citations:
4
Fields:
Env
Environmental Health
Nuc
Nuclear Medicine
Habibollahi P, Figueiredo JL,
Heidari P
, Dulak AM, Imamura Y, Bass AJ,
Ogino S
,
Chan AT
,
Mahmood U
. Optical Imaging with a Cathepsin B Activated Probe for the Enhanced Detection of Esophageal Adenocarcinoma by Dual Channel Fluorescent Upper GI Endoscopy. Theranostics. 2012; 2(2):227-34.
PMID:
22400064
.
Citations:
19
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Nan
Nanotechnology
The
Therapeutics
Quante M, Bhagat G, Abrams JA, Marache F, Good P, Lee MD, Lee Y, Friedman R, Asfaha S, Dubeykovskaya Z,
Mahmood U
, Figueiredo JL, Kitajewski J, Shawber C, Lightdale CJ, Rustgi AK, Wang TC. Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. Cancer Cell. 2012 Jan 17; 21(1):36-51.
PMID:
22264787
.
Citations:
208
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Mahmood U
, Hanlon AL, Koshy M, Buras R, Chumsri S, Tkaczuk KH, Cheston S, Regine W, Feigenberg SJ. Early evidence of increasing national mastectomy rates for the treatment of breast cancer. J Clin Oncol. 2011 Sep 20; 29(27_suppl):136.
PMID:
27958139
.
Citations:
Mahmood U
, Morris CG, Neuner GA, Koshy M, Kesmodel S, Buras R, Chumsri S, Bao T, Tkaczuk KH, Feigenberg SJ. Comparing survival with breast-conservation therapy or mastectomy in the management of young women with early-stage breast cancer. J Clin Oncol. 2011 Sep 20; 29(27_suppl):85.
PMID:
27958073
.
Citations:
Chan AT
, Baba Y, Shima K, Nosho K,
Chung DC
, Hung KE,
Mahmood U
, Madden K, Poss K, Ranieri A, Shue D,
Kucherlapati R
, Fuchs CS,
Ogino S
. Cathepsin B expression and survival in colon cancer: implications for molecular detection of neoplasia. Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11):2777-85.
PMID:
20833970
.
Citations:
24
Fields:
Bio
Biochemistry
Epi
Epidemiology
Neo
Neoplasms
Translation:
Humans
Sheth RA,
Mahmood U
. Optical molecular imaging and its emerging role in colorectal cancer. Am J Physiol Gastrointest Liver Physiol. 2010 Oct; 299(4):G807-20.
PMID:
20595618
.
Citations:
11
Fields:
Gas
Gastroenterology
Phy
Physiology
Translation:
Humans
Sheth RA, Maricevich M,
Mahmood U
. In vivo optical molecular imaging of matrix metalloproteinase activity in abdominal aortic aneurysms correlates with treatment effects on growth rate. Atherosclerosis. 2010 Sep; 212(1):181-7.
PMID:
20542274
.
Citations:
23
Fields:
Vas
Vascular Diseases
Translation:
Animals
Mahmood U
. Science to practice: can a targeted nanoparticle be used to image autoimmune nephritis? Radiology. 2010 May; 255(2):309-10.
PMID:
20413745
.
Citations:
1
Fields:
Rad
Radiology
Translation:
Animals
Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A,
Bronson RT
,
Mahmood U
,
Kucherlapati R
. Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4):1565-70.
PMID:
20080688
; PMCID:
PMC2824379
.
Citations:
118
Fields:
Sci
Science
Translation:
Animals
Cells
Ventura E, Islam T,
Gee MS
,
Mahmood U
, Braschi M,
Harisinghani MG
. Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT. Clin Imaging. 2010 Jan-Feb; 34(1):20-8.
PMID:
20122515
.
Citations:
2
Fields:
Dia
Diagnostic Imaging
Translation:
Humans
Mahmood U
. Optical molecular imaging approaches in colorectal cancer. Gastroenterology. 2010 Feb; 138(2):419-22.
PMID:
20026448
; PMCID:
PMC2896906
.
Citations:
13
Fields:
Gas
Gastroenterology
Translation:
Humans
Animals
Cells
Sheth RA,
Josephson L
,
Mahmood U
. Evaluation and clinically relevant applications of a fluorescent imaging analog to fluorodeoxyglucose positron emission tomography. J Biomed Opt. 2009 Nov-Dec; 14(6):064014.
PMID:
20059252
.
Citations:
25
Fields:
Bio
Biomedical Engineering
Oph
Ophthalmology
Translation:
Humans
Animals
Cells
Wadlow RC,
Wittner BS
, Finley SA, Bergquist H, Upadhyay R, Finn S,
Loda M
,
Mahmood U
, Ramaswamy S. Systems-level modeling of cancer-fibroblast interaction. PLoS One. 2009 Sep 03; 4(9):e6888.
PMID:
19727395
.
Citations:
15
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Mahmood U
. Science to practice: can an enzyme-sensitive MR contrast agent be used to image inflammation in aneurysms? Radiology. 2009 Sep; 252(3):627-8.
PMID:
19717746
.
Citations:
2
Fields:
Rad
Radiology
Translation:
Animals
Stangenberg L
, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A,
Yuan H
, Blois J, Smith RA,
Yaffe MB
,
Weissleder R
,
Benoist C
,
Mathis D
,
Josephson L
,
Mahmood U
. Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheum. 2009 Aug; 60(8):2314-24.
PMID:
19644878
; PMCID:
PMC3080016
.
Citations:
7
Fields:
Rhe
Rheumatology
Translation:
Animals
Cells
Yoon SS,
Stangenberg L
, Lee YJ, Rothrock C,
Dreyfuss JM
, Baek KH, Waterman PR,
Nielsen GP
,
Weissleder R
,
Mahmood U
,
Park PJ
, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG. Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2009 Jul 15; 74(4):1207-16.
PMID:
19545786
.
Citations:
25
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Animals
Hilderbrand SA, Shao F, Salthouse C,
Mahmood U
,
Weissleder R
. Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commun (Camb). 2009 Jul 28; (28):4188-90.
PMID:
19585016
.
Citations:
36
Fields:
Che
Chemistry
Translation:
Animals
Sheth RA,
Tam JM
, Maricevich MA,
Josephson L
,
Mahmood U
. Quantitative endovascular fluorescence-based molecular imaging through blood of arterial wall inflammation. Radiology. 2009 Jun; 251(3):813-21.
PMID:
19474377
; PMCID:
PMC2687531
.
Citations:
6
Fields:
Rad
Radiology
Translation:
Animals
Salthouse CD, Reynolds F,
Tam JM
,
Josephson L
,
Mahmood U
. Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects. Sens Actuators B Chem. 2009 May 06; 138(2):591-597.
PMID:
20161242
.
Citations:
4
Hung KE, Faca V, Song K, Sarracino DA, Richard LG, Krastins B, Forrester S, Porter A, Kunin A,
Mahmood U
, Haab BB, Hanash SM,
Kucherlapati R
. Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with intestinal tumorigenesis. Cancer Prev Res (Phila). 2009 Mar; 2(3):224-33.
PMID:
19240248
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Sheth RA, Upadhyay R,
Stangenberg L
, Sheth R,
Weissleder R
,
Mahmood U
. Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model. Gynecol Oncol. 2009 Mar; 112(3):616-22.
PMID:
19135233
.
Citations:
40
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Salthouse C, Hildebrand S,
Weissleder R
,
Mahmood U
. Design and demonstration of a small-animal up-conversion imager. Opt Express. 2008 Dec 22; 16(26):21731-7.
PMID:
19104605
.
Citations:
6
Fields:
Bio
Biophysics
Oph
Ophthalmology
Translation:
Animals
Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y,
Chirieac LR
, Kaur R, Lightbown A, Simendinger J, Li T,
Padera RF
, García-Echeverría C,
Weissleder R
,
Mahmood U
,
Cantley LC
, Wong KK. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med. 2008 Dec; 14(12):1351-6.
PMID:
19029981
.
Citations:
688
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Animals
Cells
Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL,
Mahmood U
, Diehl JA, Herlyn M, Rustgi AK. A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest. 2008 Dec; 118(12):3860-9.
PMID:
19033657
; PMCID:
PMC2579884
.
Citations:
60
Fields:
Med
Medicine (General)
Translation:
Animals
Cells
Kozloff KM,
Quinti L
, Patntirapong S, Hauschka PV, Tung CH,
Weissleder R
,
Mahmood U
. Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone. 2009 Feb; 44(2):190-8.
PMID:
19007918
.
Citations:
32
Fields:
Met
Metabolism
Ort
Orthopedics
Translation:
Humans
Animals
Cells
Girnun GD, Chen L, Silvaggi J, Drapkin R,
Chirieac LR
,
Padera RF
, Upadhyay R, Vafai SB,
Weissleder R
,
Mahmood U
, Naseri E, Buckley S, Li D, Force J, McNamara K,
Demetri G
,
Spiegelman BM
, Wong KK. Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. Clin Cancer Res. 2008 Oct 15; 14(20):6478-86.
PMID:
18927287
; PMCID:
PMC2696122
.
Citations:
40
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Salthouse CD,
Weissleder R
,
Mahmood U
. Development of a time domain fluorimeter for fluorescent lifetime multiplexing analysis. IEEE Trans Biomed Circuits Syst. 2008 Sep 01; 2(3):204-11.
PMID:
19830273
.
Citations:
2
Fields:
Bio
Biomedical Engineering
Bio
Biotechnology
Gee MS
, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M,
Weissleder R
,
Josephson L
,
Mahmood U
. Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy. Radiology. 2008 Sep; 248(3):925-35.
PMID:
18647846
; PMCID:
PMC2798096
.
Citations:
25
Fields:
Rad
Radiology
Translation:
Humans
Animals
Cells
Lin KY, Maricevich M, Bardeesy N,
Weissleder R
,
Mahmood U
. In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008 Jul; 1(2):84-94.
PMID:
18633456
.
Citations:
13
Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA,
Mahmood U
,
Weissleder R
. Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. PLoS Med. 2008 Apr 15; 5(4):e85.
PMID:
18416599
.
Citations:
102
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Gee MS
, Upadhyay R, Bergquist H,
Weissleder R
,
Josephson L
,
Mahmood U
. Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer. 2007 Dec 01; 121(11):2492-500.
PMID:
17683072
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Upadhyay R, Sheth RA,
Weissleder R
,
Mahmood U
. Quantitative real-time catheter-based fluorescence molecular imaging in mice. Radiology. 2007 Nov; 245(2):523-31.
PMID:
17940307
.
Citations:
28
Fields:
Rad
Radiology
Translation:
Animals
Arwert E, Hingtgen S, Figueiredo JL, Bergquist H,
Mahmood U
,
Weissleder R
,
Shah K
. Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo. Cancer Res. 2007 Aug 01; 67(15):7335-42.
PMID:
17671203
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Kozloff KM,
Weissleder R
,
Mahmood U
. Noninvasive optical detection of bone mineral. J Bone Miner Res. 2007 Aug; 22(8):1208-16.
PMID:
17488196
.
Citations:
26
Fields:
Met
Metabolism
Ort
Orthopedics
Translation:
Humans
Animals
Cells
Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L,
Mahmood U
,
Weissleder R
, Carulli J,
Benoist C
,
Mathis D
. Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. J Exp Med. 2007 Aug 06; 204(8):1911-22.
PMID:
17646407
; PMCID:
PMC2118664
.
Citations:
42
Fields:
All
Allergy and Immunology
Med
Medicine (General)
Translation:
Animals
Cells
Tam JM
, Upadhyay R,
Pittet MJ
,
Weissleder R
,
Mahmood U
. Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007 Jul-Aug; 6(4):269-76.
PMID:
17711782
.
Citations:
14
Fields:
Dia
Diagnostic Imaging
Translation:
Animals
Cells
Mahmood U
, Upadhyay R. Current and Future Imaging Paradigms in Colorectal Cancer. Semin Colon Rectal Surg. 2007 Jun; 18(2):132-138.
PMID:
18516215
.
Citations:
Alencar H, Funovics MA, Figueiredo J, Sawaya H,
Weissleder R
,
Mahmood U
. Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice. Radiology. 2007 Jul; 244(1):232-8.
PMID:
17507718
.
Citations:
45
Fields:
Rad
Radiology
Translation:
Animals
Cells
Sheth RA, Upadhyay R,
Weissleder R
,
Mahmood U
. Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging. 2007 May-Jun; 6(3):147-55.
PMID:
17532881
.
Citations:
13
Fields:
Dia
Diagnostic Imaging
Translation:
Animals
Montet X, Figueiredo JL, Alencar H, Ntziachristos V,
Mahmood U
,
Weissleder R
. Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology. 2007 Mar; 242(3):751-8.
PMID:
17325064
.
Citations:
47
Fields:
Rad
Radiology
Translation:
Animals
Cells
Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T,
Weissleder R
,
Mahmood U
, Healy AM, Jaffee B. Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arthritis Rheum. 2007 Jan; 56(1):117-28.
PMID:
17195214
.