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Umar Mahmood, M.D., Ph.D.


A Real-Time Method for Quantitative Catheter-Based Fluorescence Molecular Imaging
Summer, 06/01/05 - 09/01/05

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK123143 (MAHMOOD, UMAR) Sep 4, 2020 - May 31, 2024
    Granzyme B PET imaging as a marker of inflammatory bowel disease activity
    Role: Principal Investigator
  2. R01CA211223 (MAHMOOD, UMAR) Dec 1, 2017 - Nov 30, 2022
    Quantitative HER3 PET Imaging for Assessing Resistance and Guiding Therapy
    Role: Principal Investigator
  3. R01CA214744 (MAHMOOD, UMAR) Aug 1, 2017 - Jul 31, 2022
    Cytotoxic lymphocyte function PET imaging to predict cancer immunotherapy response
    Role: Principal Investigator
  4. U01CA202934 (MAHMOOD, UMAR) Mar 2, 2017 - Jun 30, 2022
    Optical and electromagnetic tracking guidance for hepatic interventions
    Role: Principal Investigator
  5. S10OD018004 (MAHMOOD, UMAR) Apr 15, 2014 - Apr 14, 2016
    MicroPET-MR scanner for preclinical molecular imaging
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhang C, O'Shea A, Parente CA, Amorim BJ, Caravan P, Ferrone CR, Blaszkowsky LS, Soricelli A, Salvatore M, Groshar D, Bernstine H, Domachevsky L, Canamaque LG, Umutlu L, Ken H, Catana C, Mahmood U, Catalano OA. Evaluation of the Diagnostic Performance of Positron Emission Tomography/Magnetic Resonance for the Diagnosis of Liver Metastases. Invest Radiol. 2021 Mar 25. PMID: 33813576.
    Citations:    Fields:    
  2. Husseini JS, Amorim BJ, Torrado-Carvajal A, Prabhu V, Groshar D, Umutlu L, Herrmann K, Cañamaque LG, Garzón JRG, Palmer WE, Heidari P, Shih TT, Sosna J, Matushita C, Cerci J, Queiroz M, Muglia VF, Nogueira-Barbosa MH, Borra RJH, Kwee TC, Glaudemans AWJM, Evangelista L, Salvatore M, Cuocolo A, Soricelli A, Herold C, Laghi A, Mayerhoefer M, Mahmood U, Catana C, Daldrup-Link HE, Rosen B, Catalano OA. An international expert opinion statement on the utility of PET/MR for imaging of skeletal metastases. Eur J Nucl Med Mol Imaging. 2021 May; 48(5):1522-1537. PMID: 33619599.
    Citations:    Fields:    
  3. Biondetti P, Vangel MG, Lahoud RM, Furtado FS, Rosen BR, Groshar D, Canamaque LG, Umutlu L, Zhang EW, Mahmood U, Digumarthy SR, Shepard JO, Catalano OA. PET/MRI assessment of lung nodules in primary abdominal malignancies: sensitivity and outcome analysis. Eur J Nucl Med Mol Imaging. 2021 Jun; 48(6):1976-1986. PMID: 33415433.
    Citations:    Fields:    
  4. Tan BS, Dunnick NR, Gangi A, Goergen S, Jin ZY, Neri E, Nomura CH, Pitcher RD, Yee J, Mahmood U. RSNA International Trends: A Global Perspective on the COVID-19 Pandemic and Radiology in Late 2020. Radiology. 2021 04; 299(1):E193-E203. PMID: 33289616.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  5. Sinevici N, Ataeinia B, Zehnder V, Lin K, Grove L, Heidari P, Mahmood U. HER3 Differentiates Basal From Claudin Type Triple Negative Breast Cancer and Contributes to Drug and Microenvironmental Induced Resistance. Front Oncol. 2020; 10:554704. PMID: 33330026.
  6. Silva CF, Elizondo-Rojas G, Atalabi O, Karçaaltincaba M, Morana G, Mahmood U. RSNA Committee on International Radiology Education: 25 Years of Global Education Outreach. Radiographics. 2020 Nov-Dec; 40(7):1938-1952. PMID: 33136478.
    Citations:    Fields:    
  7. Catalano OA, Lee SI, Parente C, Cauley C, Furtado FS, Striar R, Soricelli A, Salvatore M, Li Y, Umutlu L, Cañamaque LG, Groshar D, Mahmood U, Blaszkowsky LS, Ryan DP, Clark JW, Wo J, Hong TS, Kunitake H, Bordeianou L, Berger D, Ricciardi R, Rosen B. Improving staging of rectal cancer in the pelvis: the role of PET/MRI. Eur J Nucl Med Mol Imaging. 2021 Apr; 48(4):1235-1245. PMID: 33034673.
    Citations:    Fields:    
  8. Xu J, Higgins MJ, Tolaney SM, Come SE, Smith MR, Fornier M, Mahmood U, Baselga J, Yeap BY, Chabner BA, Isakoff SJ. A Phase II Trial of Cabozantinib in Hormone Receptor-Positive Breast Cancer with Bone Metastases. Oncologist. 2020 08; 25(8):652-660. PMID: 32463152.
    Citations: 2     Fields:    
  9. LaSalle T, Austin EE, Rigney G, Wehrenberg-Klee E, Nesti S, Larimer B, Mahmood U. Granzyme B PET imaging of immune-mediated tumor killing as a tool for understanding immunotherapy response. J Immunother Cancer. 2020 05; 8(1). PMID: 32461343.
    Citations: 4     Fields:    
  10. Tam J, Pilozzi A, Mahmood U, Huang X. Simultaneous Monitoring of Multi-Enzyme Activity and Concentration in Tumor Using a Triply Labeled Fluorescent In Vivo Imaging Probe. Int J Mol Sci. 2020 Apr 27; 21(9). PMID: 32349205.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Ferrone C, Goyal L, Qadan M, Gervais D, Sahani DV, Zhu AX, Hong TS, Blaszkowsky LS, Tanabe KK, Vangel M, Amorim BJ, Wo JY, Mahmood U, Pandharipande PV, Catana C, Duenas VP, Collazo YQ, Canamaque LG, Domachevsky L, Bernstine HH, Groshar D, Shih TT, Li Y, Herrmann K, Umutlu L, Rosen BR, Catalano OA. Management implications of fluorodeoxyglucose positron emission tomography/magnetic resonance in untreated intrahepatic cholangiocarcinoma. Eur J Nucl Med Mol Imaging. 2020 07; 47(8):1871-1884. PMID: 31705172.
    Citations: 4     Fields:    
  12. Esfahani SA, Heidari P, Kucherlapati MH, Ferrer JM, Kucherlapati RS, Mahmood U. Optical imaging with a novel cathepsin-activatable probe for enhanced detection of colorectal cancer. Am J Nucl Med Mol Imaging. 2019; 9(5):230-242. PMID: 31772821.
  13. Amorim BJ, Hong TS, Blaszkowsky LS, Ferrone CR, Berger DL, Bordeianou LG, Ricciardi R, Clark JW, Ryan DP, Wo JY, Qadan M, Vangel M, Umutlu L, Groshar D, Cañamaques LG, Gervais DA, Mahmood U, Rosen BR, Catalano OA. Clinical impact of PET/MR in treated colorectal cancer patients. Eur J Nucl Med Mol Imaging. 2019 Oct; 46(11):2260-2269. PMID: 31359108.
    Citations: 4     Fields:    Translation:Humans
  14. Gilbert TM, Zürcher NR, Catanese MC, Tseng CJ, Di Biase MA, Lyall AE, Hightower BG, Parmar AJ, Bhanot A, Wu CJ, Hibert ML, Kim M, Mahmood U, Stufflebeam SM, Schroeder FA, Wang C, Roffman JL, Holt DJ, Greve DN, Pasternak O, Kubicki M, Wey HY, Hooker JM. Neuroepigenetic signatures of age and sex in the living human brain. Nat Commun. 2019 07 03; 10(1):2945. PMID: 31270332.
    Citations: 6     Fields:    Translation:Humans
  15. Wang Y, Ayres KL, Goldman DA, Dickler MN, Bardia A, Mayer IA, Winer E, Fredrickson J, Arteaga CL, Baselga J, Manning HC, Mahmood U, Ulaner GA. Correction: 18F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials. Clin Cancer Res. 2019 Feb 15; 25(4):1435. PMID: 30770494.
    Citations: 1     Fields:    
  16. Andriole GL, Kostakoglu L, Chau A, Duan F, Mahmood U, Mankoff DA, Schuster DM, Siegel BA. The Impact of Positron Emission Tomography with 18F-Fluciclovine on the Treatment of Biochemical Recurrence of Prostate Cancer: Results from the LOCATE Trial. J Urol. 2019 02; 201(2):322-331. PMID: 30179618.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  17. Zadra G, Ribeiro CF, Chetta P, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y, Tyekucheva S, Bastos DC, Tchaicha J, Lawney B, Uo T, D'Anello L, Csibi A, Kalekar R, Larimer B, Ellis L, Butler LM, Morrissey C, McGovern K, Palombella VJ, Kutok JL, Mahmood U, Bosari S, Adams J, Peluso S, Dehm SM, Plymate SR, Loda M. Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2019 01 08; 116(2):631-640. PMID: 30578319.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  18. Larimer BM, Bloch E, Nesti S, Austin EE, Wehrenberg-Klee E, Boland G, Mahmood U. The Effectiveness of Checkpoint Inhibitor Combinations and Administration Timing Can Be Measured by Granzyme B PET Imaging. Clin Cancer Res. 2019 02 15; 25(4):1196-1205. PMID: 30327313.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  19. Ferry-Galow KV, Datta V, Makhlouf HR, Wright J, Wood BJ, Levy E, Pisano ED, Tam AL, Lee SI, Mahmood U, Rubinstein LV, Doroshow JH, Chen AP. What Can Be Done to Improve Research Biopsy Quality in Oncology Clinical Trials? J Oncol Pract. 2018 Oct 04; JOP1800092. PMID: 30285529.
    Citations: 6     Fields:    
  20. Catalano O, Kilcoyne A, Signore A, Mahmood U, Rosen B. Lower Gastrointestinal Tract Applications of PET/Computed Tomography and PET/MR Imaging. Radiol Clin North Am. 2018 Sep; 56(5):821-834. PMID: 30119776.
    Citations: 2     Fields:    Translation:Humans
  21. Hanna GJ, Supplee JG, Kuang Y, Mahmood U, Lau CJ, Haddad RI, Jänne PA, Paweletz CP. Plasma HPV cell-free DNA monitoring in advanced HPV-associated oropharyngeal cancer. Ann Oncol. 2018 09 01; 29(9):1980-1986. PMID: 30010779.
    Citations: 10     Fields:    Translation:HumansCells
  22. Catalano OA, Umutlu L, Fuin N, Hibert ML, Scipioni M, Pedemonte S, Vangel M, Catana AM, Herrmann K, Nensa F, Groshar D, Mahmood U, Rosen BR, Catana C. Comparison of the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo). Eur J Nucl Med Mol Imaging. 2018 11; 45(12):2147-2154. PMID: 29998420.
    Citations: 2     Fields:    Translation:Humans
  23. Wang Y, Rapalino O, Heidari P, Loeffler J, Shih HA, Oh K, Mahmood U. C11 Methionine PET (MET-PET) Imaging of Glioblastoma for Detecting Postoperative Residual Disease and Response to Chemoradiation Therapy. Int J Radiat Oncol Biol Phys. 2018 11 15; 102(4):1024-1028. PMID: 29913253.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  24. Larimer BM, Dubois F, Bloch E, Nesti S, Placzek M, Zadra G, Hooker JM, Loda M, Mahmood U. Specific 18F-FDHT Accumulation in Human Prostate Cancer Xenograft Murine Models Is Facilitated by Prebinding to Sex Hormone-Binding Globulin. J Nucl Med. 2018 10; 59(10):1538-1543. PMID: 29853654.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  25. Heidari P, Kunawudhi A, Martinez-Quintanilla J, Szretter A, Shah K, Mahmood U. Somatostatin receptor type 2 as a radiotheranostic PET reporter gene for oncologic interventions. Theranostics. 2018; 8(12):3380-3391. PMID: 29930736.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  26. Li Q, Xiang F, Lin X, Grajo JR, Yang L, Xu Y, Duan Y, Vyas U, Harisinghani M, Mahmood U, Samir AE. The Role of Imaging in Prostate Cancer Care Pathway: Novel Approaches to Urologic Management Challenges Along 10 Imaging Touch Points. Urology. 2018 Sep; 119:23-31. PMID: 29730256.
    Citations: 3     Fields:    Translation:Humans
  27. Larimer BM, Phelan N, Wehrenberg-Klee E, Mahmood U. Phage Display Selection, In Vitro Characterization, and Correlative PET Imaging of a Novel HER3 Peptide. Mol Imaging Biol. 2018 04; 20(2):300-308. PMID: 28733706.
    Citations: 5     Fields:    Translation:AnimalsCells
  28. Catalano OA, Wu V, Mahmood U, Signore A, Vangel M, Soricelli A, Salvatore M, Gervais D, Rosen BR. Diagnostic performance of PET/MR in the evaluation of active inflammation in Crohn disease. Am J Nucl Med Mol Imaging. 2018; 8(1):62-69. PMID: 29531862.
    Citations: 6     
  29. Jadvar H, Chen X, Cai W, Mahmood U. Radiotheranostics in Cancer Diagnosis and Management. Radiology. 2018 02; 286(2):388-400. PMID: 29356634.
    Citations: 14     Fields:    Translation:Humans
  30. Wang Y, Yee AJ, Sirard C, Landau S, Raje N, Mahmood U. Sodium fluoride PET imaging as a quantitative pharmacodynamic biomarker for bone homeostasis during anti-DKK1 therapy for multiple myeloma. Blood Cancer J. 2017 10 06; 7(10):e615. PMID: 28984867.
    Citations: 2     Fields:    Translation:Humans
  31. Collier TL, Normandin MD, Stephenson NA, Livni E, Liang SH, Wooten DW, Esfahani SA, Stabin MG, Mahmood U, Chen J, Wang W, Maresca K, Waterhouse RN, El Fakhri G, Richardson P, Vasdev N. Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib. Nat Commun. 2017 06 08; 8:15761. PMID: 28594000.
    Citations: 9     Fields:    Translation:HumansAnimals
  32. Catalano OA, Daye D, Signore A, Iannace C, Vangel M, Luongo A, Catalano M, Filomena M, Mansi L, Soricelli A, Salvatore M, Fuin N, Catana C, Mahmood U, Rosen BR. Staging performance of whole-body DWI, PET/CT and PET/MRI in invasive ductal carcinoma of the breast. Int J Oncol. 2017 Jul; 51(1):281-288. PMID: 28535000.
    Citations: 17     Fields:    Translation:Humans
  33. Holliday EB, Kuban DA, Levy LB, Bolukbasi Y, Master P, Choi S, Nguyen Q, McGuire SE, Mahmood U, Frank SJ, Hoffman KE. Select men benefit from androgen deprivation therapy delivered with salvage radiation therapy after prostatectomy. Prostate Cancer Prostatic Dis. 2017 12; 20(4):389-394. PMID: 28462945.
    Citations: 1     Fields:    Translation:Humans
  34. Larimer BM, Wehrenberg-Klee E, Dubois F, Mehta A, Kalomeris T, Flaherty K, Boland G, Mahmood U. Granzyme B PET Imaging as a Predictive Biomarker of Immunotherapy Response. Cancer Res. 2017 05 01; 77(9):2318-2327. PMID: 28461564.
    Citations: 60     Fields:    Translation:HumansAnimalsCells
  35. Esfahani SA, Salcedo S, Heidari P, Catalano OA, Pauplis R, Hesterman J, Kronauge JF, Mahmood U. A phase one, single-dose, open-label, clinical safety and PET/MR imaging study of 68Ga-DOTATOC in healthy volunteers. Am J Nucl Med Mol Imaging. 2017; 7(2):53-62. PMID: 28533937.
    Citations: 2     
  36. Catalano OA, Coutinho AM, Sahani DV, Vangel MG, Gee MS, Hahn PF, Witzel T, Soricelli A, Salvatore M, Catana C, Mahmood U, Rosen BR, Gervais D. Colorectal cancer staging: comparison of whole-body PET/CT and PET/MR. Abdom Radiol (NY). 2017 04; 42(4):1141-1151. PMID: 27891551.
    Citations: 7     Fields:    Translation:Humans
  37. Catalano OA, Horn GL, Signore A, Iannace C, Lepore M, Vangel M, Luongo A, Catalano M, Lehman C, Salvatore M, Soricelli A, Catana C, Mahmood U, Rosen BR. PET/MR in invasive ductal breast cancer: correlation between imaging markers and histological phenotype. Br J Cancer. 2017 Mar 28; 116(7):893-902. PMID: 28208155.
    Citations: 8     Fields:    Translation:Humans
  38. Catalano OA, Masch WR, Catana C, Mahmood U, Sahani DV, Gee MS, Menezes L, Soricelli A, Salvatore M, Gervais D, Rosen BR. An overview of PET/MR, focused on clinical applications. Abdom Radiol (NY). 2017 02; 42(2):631-644. PMID: 27624499.
    Citations: 4     Fields:    Translation:Humans
  39. Wang Y, Ayres KL, Goldman DA, Dickler MN, Bardia A, Mayer IA, Winer E, Fredrickson J, Arteaga CL, Baselga J, Manning HC, Mahmood U, Ulaner GA. 18F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials. Clin Cancer Res. 2017 Jun 15; 23(12):3053-3060. PMID: 28011460.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  40. Qian ZR, Li T, Ter-Minassian M, Yang J, Chan JA, Brais LK, Masugi Y, Thiaglingam A, Brooks N, Nishihara R, Bonnemarie M, Masuda A, Inamura K, Kim SA, Mima K, Sukawa Y, Dou R, Lin X, Christiani DC, Schmidlin F, Fuchs CS, Mahmood U, Ogino S, Kulke MH. Association Between Somatostatin Receptor Expression and Clinical Outcomes in Neuroendocrine Tumors. Pancreas. 2016 11; 45(10):1386-1393. PMID: 27622342.
    Citations: 25     Fields:    Translation:Humans
  41. Kilcoyne A, Harisinghani MG, Mahmood U. Prostate Cancer Imaging and Therapy: Potential Role of Nanoparticles. J Nucl Med. 2016 Oct; 57(Suppl 3):105S-110S. PMID: 27694162.
    Citations: 2     Fields:    Translation:HumansAnimals
  42. Wang Y, Oh KS, Loeffler JS, Shih HA, Mahmood U. C11 Methionine Positron Emission Tomography (MET-PET) Imaging of Glioblastoma for Detecting Postoperative Residual Disease and Response to Chemoradiation Therapy. Int J Radiat Oncol Biol Phys. 2016 Oct 1; 96(2S):E93. PMID: 27675505.
  43. Esfahani SA, Heidari P, Kim SA, Ogino S, Mahmood U. Optical Imaging of Mesenchymal Epithelial Transition Factor (MET) for Enhanced Detection and Characterization of Primary and Metastatic Hepatic Tumors. Theranostics. 2016; 6(12):2028-2038. PMID: 27698938.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  44. Heidari P, Szretter A, Rushford LE, Stevens M, Collier L, Sore J, Hooker J, Mahmood U. Design, construction and testing of a low-cost automated (68)Gallium-labeling synthesis unit for clinical use. Am J Nucl Med Mol Imaging. 2016; 6(3):176-84. PMID: 27508104.
    Citations: 4     
  45. Larimer BM, Wehrenberg-Klee E, Caraballo A, Mahmood U. Quantitative CD3 PET Imaging Predicts Tumor Growth Response to Anti-CTLA-4 Therapy. J Nucl Med. 2016 Oct; 57(10):1607-1611. PMID: 27230929.
    Citations: 34     Fields:    Translation:AnimalsCells
  46. McPartlin AJ, Li XA, Kershaw LE, Heide U, Kerkmeijer L, Lawton C, Mahmood U, Pos F, van As N, van Herk M, Vesprini D, van der Voort van Zyp J, Tree A, Choudhury A. MRI-guided prostate adaptive radiotherapy - A systematic review. Radiother Oncol. 2016 06; 119(3):371-80. PMID: 27162159.
    Citations: 24     Fields:    Translation:Humans
  47. Wehrenberg-Klee E, Turker NS, Heidari P, Larimer B, Juric D, Baselga J, Scaltriti M, Mahmood U. Differential Receptor Tyrosine Kinase PET Imaging for Therapeutic Guidance. J Nucl Med. 2016 09; 57(9):1413-9. PMID: 27081168.
    Citations: 11     Fields:    Translation:HumansCells
  48. Pugmire BS, Guimaraes AR, Lim R, Friedmann AM, Huang M, Ebb D, Weinstein H, Catalano OA, Mahmood U, Catana C, Gee MS. Simultaneous whole body (18)F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging for evaluation of pediatric cancer: Preliminary experience and comparison with (18)F-fluorodeoxyglucose positron emission tomography computed tomography. World J Radiol. 2016 Mar 28; 8(3):322-30. PMID: 27028112.
    Citations: 2     
  49. Sheth RA, Heidari P, Woods K, Chung D, Chan AT, Mahmood U. Pilot Clinical Trial of Indocyanine Green Fluorescence-Augmented Colonoscopy in High Risk Patients. Gastroenterol Res Pract. 2016; 2016:6184842. PMID: 26989406.
    Citations: 1     
  50. Kunawudhi A, Wong AK, Alkasab TK, Mahmood U. Accuracy of FDG-PET/CT for Detection of Incidental Pre-Malignant and Malignant Colonic Lesions - Correlation with Colonoscopic and Histopathologic Findings. Asian Pac J Cancer Prev. 2016; 17(8):4143-7. PMID: 27644675.
    Citations: 2     Fields:    Translation:Humans
  51. Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 2015 Dec 14; 28(6):831-833. PMID: 28843279.
    Citations: 40     Fields:    
  52. Mahmood U. 2015 SNMMI Highlights Lecture: Oncology, Part II. J Nucl Med. 2015 Dec; 56(12):9N-16N. PMID: 26626870.
    Citations:    Fields:    Translation:HumansAnimals
  53. Mahmood U. 2015 SNMMI Highlights Lecture: Oncology, Part I. J Nucl Med. 2015 Nov; 56(11):9N-16N. PMID: 26526798.
    Citations:    Fields:    Translation:HumansAnimals
  54. Wehrenberg-Klee E, Redjal N, Leece A, Turker NS, Heidari P, Shah K, Mahmood U. PET imaging of glioblastoma multiforme EGFR expression for therapeutic decision guidance. Am J Nucl Med Mol Imaging. 2015; 5(4):379-89. PMID: 26269775.
    Citations: 6     
  55. Heidari P, Esfahani SA, Turker NS, Wong G, Wang TC, Rustgi AK, Mahmood U. Imaging of Secreted Extracellular Periostin, an Important Marker of Invasion in the Tumor Microenvironment in Esophageal Cancer. J Nucl Med. 2015 Aug; 56(8):1246-51. PMID: 26069303.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  56. Catalano OA, Nicolai E, Rosen BR, Luongo A, Catalano M, Iannace C, Guimaraes A, Vangel MG, Mahmood U, Soricelli A, Salvatore M. Comparison of CE-FDG-PET/CT with CE-FDG-PET/MR in the evaluation of osseous metastases in breast cancer patients. Br J Cancer. 2015 Apr 28; 112(9):1452-60. PMID: 25871331.
    Citations: 28     Fields:    Translation:Humans
  57. Arvold ND, Heidari P, Kunawudhi A, Sequist LV, Mahmood U. Tumor Hypoxia Response After Targeted Therapy in EGFR-Mutant Non-Small Cell Lung Cancer: Proof of Concept for FMISO-PET. Technol Cancer Res Treat. 2016 Apr; 15(2):234-42. PMID: 25759424.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  58. Leahy AA, Esfahani SA, Foote AT, Hui CK, Rainbow RS, Nakamura DS, Tracey BH, Mahmood U, Zeng L. Analysis of the trajectory of osteoarthritis development in a mouse model by serial near-infrared fluorescence imaging of matrix metalloproteinase activities. Arthritis Rheumatol. 2015 Feb; 67(2):442-53. PMID: 25385707.
    Citations: 12     Fields:    Translation:AnimalsCells
  59. Heidari P, Deng F, Esfahani SA, Leece AK, Shoup TM, Vasdev N, Mahmood U. Pharmacodynamic imaging guides dosing of a selective estrogen receptor degrader. Clin Cancer Res. 2015 Mar 15; 21(6):1340-7. PMID: 25609068.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  60. Gupta S, Mahmood U, Gurung S, Shrestha S, Kushner AL, Nwomeh BC, Charles AG. Burns in Nepal: A population based national assessment. Burns. 2015 Aug; 41(5):1126-32. PMID: 25523087.
    Citations: 12     Fields:    Translation:Humans
  61. Mahmood U. 2014 SNMMI highlights lecture: Oncology. J Nucl Med. 2014 Nov; 55(11):9N-24N. PMID: 25368337.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  62. Sheth RA, Arellano RS, Uppot RN, Samir AE, Goyal L, Zhu AX, Gervais DA, Mahmood U. Prospective trial with optical molecular imaging for percutaneous interventions in focal hepatic lesions. Radiology. 2015 Mar; 274(3):917-26. PMID: 25302707.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  63. Zadra G, Photopoulos C, Tyekucheva S, Heidari P, Weng QP, Fedele G, Liu H, Scaglia N, Priolo C, Sicinska E, Mahmood U, Signoretti S, Birnberg N, Loda M. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014; 6(10):1357. PMID: 25178544.
  64. Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D. Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):11419-24. PMID: 25049388.
    Citations: 24     Fields:    Translation:AnimalsCells
  65. Turker NS, Heidari P, Kucherlapati R, Kucherlapati M, Mahmood U. An EGFR targeted PET imaging probe for the detection of colonic adenocarcinomas in the setting of colitis. Theranostics. 2014; 4(9):893-903. PMID: 25057314.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  66. Kuruppu D, Brownell AL, Shah K, Mahmood U, Tanabe KK. Molecular imaging with bioluminescence and PET reveals viral oncolysis kinetics and tumor viability. Cancer Res. 2014 Aug 01; 74(15):4111-21. PMID: 24876106.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  67. Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014 Jun 16; 25(6):719-34. PMID: 24856586.
    Citations: 670     Fields:    Translation:HumansAnimalsCells
  68. Habibollahi P, Waldron T, Heidari P, Cho HS, Alcantara D, Josephson L, Wang TC, Rustgi AK, Mahmood U. Fluorescent Nanoparticle Imaging Allows Noninvasive Evaluation of Immune Cell Modulation in Esophageal Dysplasia. Mol Imaging. 2014 May 01; 13(3):7290201400003. PMID: 28650303.
  69. Sheth RA, Heidari P, Esfahani SA, Wood BJ, Mahmood U. Interventional optical molecular imaging guidance during percutaneous biopsy. Radiology. 2014 Jun; 271(3):770-7. PMID: 24520946.
    Citations: 12     Fields:    Translation:Animals
  70. Zadra G, Photopoulos C, Tyekucheva S, Heidari P, Weng QP, Fedele G, Liu H, Scaglia N, Priolo C, Sicinska E, Mahmood U, Signoretti S, Birnberg N, Loda M. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014 04; 6(4):519-38. PMID: 24497570.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  71. Habibollahi P, Waldron T, Heidari P, Cho HS, Alcantara D, Josephson L, Wang TC, Rustgi AK, Mahmood U. Fluorescent nanoparticle imaging allows noninvasive evaluation of immune cell modulation in esophageal dysplasia. Mol Imaging. 2014; 13:1-11. PMID: 24824854.
    Citations: 5     Fields:    Translation:AnimalsCells
  72. Heidari P, Wehrenberg-Klee E, Habibollahi P, Yokell D, Kulke M, Mahmood U. Free somatostatin receptor fraction predicts the antiproliferative effect of octreotide in a neuroendocrine tumor model: implications for dose optimization. Cancer Res. 2013 Dec 01; 73(23):6865-73. PMID: 24080280.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  73. Martinez-Quintanilla J, Bhere D, Heidari P, He D, Mahmood U, Shah K. Therapeutic efficacy and fate of bimodal engineered stem cells in malignant brain tumors. Stem Cells. 2013 Aug; 31(8):1706-14. PMID: 23389839.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  74. Kucherlapati MH, Esfahani S, Habibollahi P, Wang J, Still ER, Bronson RT, Mahmood U, Kucherlapati RS. Genotype directed therapy in murine mismatch repair deficient tumors. PLoS One. 2013; 8(7):e68817. PMID: 23935891.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  75. Leece AK, Heidari P, Yokell DL, Mahmood U. A container closure system that allows for greater recovery of radiolabeled peptide compared to the standard borosilicate glass system. Appl Radiat Isot. 2013 Oct; 80:99-102. PMID: 23860127.
    Citations: 3     Fields:    
  76. Esfahani SA, Heidari P, Halpern EF, Hochberg EP, Palmer EL, Mahmood U. Baseline total lesion glycolysis measured with (18)F-FDG PET/CT as a predictor of progression-free survival in diffuse large B-cell lymphoma: a pilot study. Am J Nucl Med Mol Imaging. 2013; 3(3):272-81. PMID: 23638338.
    Citations: 27     
  77. Martin ES, Belmont PJ, Sinnamon MJ, Richard LG, Yuan J, Coffee EM, Roper J, Lee L, Heidari P, Lunt SY, Goel G, Ji X, Xie Z, Xie T, Lamb J, Weinrich SL, VanArsdale T, Bronson RT, Xavier RJ, Vander Heiden MG, Kan JL, Mahmood U, Hung KE. Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation. Clin Cancer Res. 2013 Jun 01; 19(11):2929-40. PMID: 23403635.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  78. Cho H, Alcantara D, Yuan H, Sheth RA, Chen HH, Huang P, Andersson SB, Sosnovik DE, Mahmood U, Josephson L. Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems. ACS Nano. 2013 Mar 26; 7(3):2032-41. PMID: 23373524.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  79. Habibollahi P, van den Berg NS, Kuruppu D, Loda M, Mahmood U. Metformin--an adjunct antineoplastic therapy--divergently modulates tumor metabolism and proliferation, interfering with early response prediction by 18F-FDG PET imaging. J Nucl Med. 2013 Feb; 54(2):252-8. PMID: 23376854.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  80. Wong GS, Habibollahi P, Heidari P, Lee JS, Klein-Szanto AJ, Waldron TJ, Gimotty P, Nakagawa H, Taylor PR, Wang TC, Mahmood U, Rustgi AK. Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice. Gastroenterology. 2013 Feb; 144(2):294-7. PMID: 23085486.
    Citations: 12     Fields:    Translation:HumansAnimals
  81. Saylor PJ, Mahmood U, Kunawudhi A, Smith MR, Palmer EL, Michaelson MD. Multitargeted tyrosine kinase inhibition produces discordant changes between 99mTc-MDP bone scans and other disease biomarkers: analysis of a phase II study of sunitinib for metastatic castration-resistant prostate cancer. J Nucl Med. 2012 Nov; 53(11):1670-5. PMID: 22984218.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  82. Sheth RA, Kunin A, Stangenberg L, Sinnamon M, Hung KE, Kucherlapati R, Mahmood U. In vivo optical molecular imaging of matrix metalloproteinase activity following celecoxib therapy for colorectal cancer. Mol Imaging. 2012 Sep-Oct; 11(5):417-25. PMID: 22954186.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  83. Yokell DL, Leece AK, Lebedev A, Miraghaie R, Ball CE, Zhang J, Kolb H, Elizarov A, Mahmood U. Microfluidic single vessel production of hypoxia tracer 1H-1-(3-[18F]-fluoro-2-hydroxy-propyl)-2-nitro-imidazole ([18F]-FMISO). Appl Radiat Isot. 2012 Oct; 70(10):2313-6. PMID: 22871433.
    Citations: 2     Fields:    
  84. Habibollahi P, Figueiredo JL, Heidari P, Dulak AM, Imamura Y, Bass AJ, Ogino S, Chan AT, Mahmood U. Optical Imaging with a Cathepsin B Activated Probe for the Enhanced Detection of Esophageal Adenocarcinoma by Dual Channel Fluorescent Upper GI Endoscopy. Theranostics. 2012; 2(2):227-34. PMID: 22400064.
    Citations: 15     Fields:    
  85. Quante M, Bhagat G, Abrams JA, Marache F, Good P, Lee MD, Lee Y, Friedman R, Asfaha S, Dubeykovskaya Z, Mahmood U, Figueiredo JL, Kitajewski J, Shawber C, Lightdale CJ, Rustgi AK, Wang TC. Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. Cancer Cell. 2012 Jan 17; 21(1):36-51. PMID: 22264787.
    Citations: 154     Fields:    Translation:AnimalsCells
  86. Mahmood U, Morris CG, Neuner GA, Koshy M, Kesmodel S, Buras R, Chumsri S, Bao T, Tkaczuk KH, Feigenberg SJ. Comparing survival with breast-conservation therapy or mastectomy in the management of young women with early-stage breast cancer. J Clin Oncol. 2011 Sep 20; 29(27_suppl):85. PMID: 27958073.
  87. Mahmood U, Hanlon AL, Koshy M, Buras R, Chumsri S, Tkaczuk KH, Cheston S, Regine W, Feigenberg SJ. Early evidence of increasing national mastectomy rates for the treatment of breast cancer. J Clin Oncol. 2011 Sep 20; 29(27_suppl):136. PMID: 27958139.
  88. Chan AT, Baba Y, Shima K, Nosho K, Chung DC, Hung KE, Mahmood U, Madden K, Poss K, Ranieri A, Shue D, Kucherlapati R, Fuchs CS, Ogino S. Cathepsin B expression and survival in colon cancer: implications for molecular detection of neoplasia. Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11):2777-85. PMID: 20833970.
    Citations: 18     Fields:    Translation:Humans
  89. Sheth RA, Mahmood U. Optical molecular imaging and its emerging role in colorectal cancer. Am J Physiol Gastrointest Liver Physiol. 2010 Oct; 299(4):G807-20. PMID: 20595618.
    Citations: 11     Fields:    Translation:Humans
  90. Sheth RA, Maricevich M, Mahmood U. In vivo optical molecular imaging of matrix metalloproteinase activity in abdominal aortic aneurysms correlates with treatment effects on growth rate. Atherosclerosis. 2010 Sep; 212(1):181-7. PMID: 20542274.
    Citations: 20     Fields:    Translation:Animals
  91. Mahmood U. Science to practice: can a targeted nanoparticle be used to image autoimmune nephritis? Radiology. 2010 May; 255(2):309-10. PMID: 20413745.
    Citations: 1     Fields:    Translation:Animals
  92. Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A, Bronson RT, Mahmood U, Kucherlapati R. Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4):1565-70. PMID: 20080688.
    Citations: 106     Fields:    Translation:AnimalsCells
  93. Ventura E, Islam T, Gee MS, Mahmood U, Braschi M, Harisinghani MG. Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT. Clin Imaging. 2010 Jan-Feb; 34(1):20-8. PMID: 20122515.
    Citations: 1     Fields:    Translation:Humans
  94. Mahmood U. Optical molecular imaging approaches in colorectal cancer. Gastroenterology. 2010 Feb; 138(2):419-22. PMID: 20026448.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  95. Sheth RA, Josephson L, Mahmood U. Evaluation and clinically relevant applications of a fluorescent imaging analog to fluorodeoxyglucose positron emission tomography. J Biomed Opt. 2009 Nov-Dec; 14(6):064014. PMID: 20059252.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  96. Wadlow RC, Wittner BS, Finley SA, Bergquist H, Upadhyay R, Finn S, Loda M, Mahmood U, Ramaswamy S. Systems-level modeling of cancer-fibroblast interaction. PLoS One. 2009 Sep 03; 4(9):e6888. PMID: 19727395.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  97. Mahmood U. Science to practice: can an enzyme-sensitive MR contrast agent be used to image inflammation in aneurysms? Radiology. 2009 Sep; 252(3):627-8. PMID: 19717746.
    Citations: 2     Fields:    Translation:Animals
  98. Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U. Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheum. 2009 Aug; 60(8):2314-24. PMID: 19644878.
    Citations: 7     Fields:    Translation:AnimalsCells
  99. Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG. Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2009 Jul 15; 74(4):1207-16. PMID: 19545786.
    Citations: 23     Fields:    Translation:Animals
  100. Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R. Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commun (Camb). 2009 Jul 28; (28):4188-90. PMID: 19585016.
    Citations: 33     Fields:    Translation:Animals
  101. Sheth RA, Tam JM, Maricevich MA, Josephson L, Mahmood U. Quantitative endovascular fluorescence-based molecular imaging through blood of arterial wall inflammation. Radiology. 2009 Jun; 251(3):813-21. PMID: 19474377.
    Citations: 5     Fields:    Translation:Animals
  102. Salthouse CD, Reynolds F, Tam JM, Josephson L, Mahmood U. Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects. Sens Actuators B Chem. 2009 May 06; 138(2):591-597. PMID: 20161242.
    Citations: 4     
  103. Hung KE, Faca V, Song K, Sarracino DA, Richard LG, Krastins B, Forrester S, Porter A, Kunin A, Mahmood U, Haab BB, Hanash SM, Kucherlapati R. Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with intestinal tumorigenesis. Cancer Prev Res (Phila). 2009 Mar; 2(3):224-33. PMID: 19240248.
    Citations: 25     Fields:    Translation:AnimalsCells
  104. Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U. Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model. Gynecol Oncol. 2009 Mar; 112(3):616-22. PMID: 19135233.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  105. Salthouse C, Hildebrand S, Weissleder R, Mahmood U. Design and demonstration of a small-animal up-conversion imager. Opt Express. 2008 Dec 22; 16(26):21731-7. PMID: 19104605.
    Citations: 6     Fields:    Translation:Animals
  106. Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, García-Echeverría C, Weissleder R, Mahmood U, Cantley LC, Wong KK. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med. 2008 Dec; 14(12):1351-6. PMID: 19029981.
    Citations: 623     Fields:    Translation:AnimalsCells
  107. Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK. A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest. 2008 Dec; 118(12):3860-9. PMID: 19033657.
    Citations: 51     Fields:    Translation:AnimalsCells
  108. Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U. Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone. 2009 Feb; 44(2):190-8. PMID: 19007918.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  109. Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK. Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. Clin Cancer Res. 2008 Oct 15; 14(20):6478-86. PMID: 18927287.
    Citations: 35     Fields:    Translation:HumansAnimals
  110. Salthouse CD, Weissleder R, Mahmood U. Development of a time domain fluorimeter for fluorescent lifetime multiplexing analysis. IEEE Trans Biomed Circuits Syst. 2008 Sep 01; 2(3):204-11. PMID: 19830273.
    Citations: 1     Fields:    
  111. Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U. Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy. Radiology. 2008 Sep; 248(3):925-35. PMID: 18647846.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  112. Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U. In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008 Jul; 1(2):84-94. PMID: 18633456.
    Citations: 13     
  113. Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R. Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. PLoS Med. 2008 Apr 15; 5(4):e85. PMID: 18416599.
    Citations: 91     Fields:    Translation:HumansAnimalsCells
  114. Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U. Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer. 2007 Dec 01; 121(11):2492-500. PMID: 17683072.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  115. Upadhyay R, Sheth RA, Weissleder R, Mahmood U. Quantitative real-time catheter-based fluorescence molecular imaging in mice. Radiology. 2007 Nov; 245(2):523-31. PMID: 17940307.
    Citations: 26     Fields:    Translation:Animals
  116. Kozloff KM, Weissleder R, Mahmood U. Noninvasive optical detection of bone mineral. J Bone Miner Res. 2007 Aug; 22(8):1208-16. PMID: 17488196.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  117. Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K. Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo. Cancer Res. 2007 Aug 01; 67(15):7335-42. PMID: 17671203.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  118. Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D. Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. J Exp Med. 2007 Aug 06; 204(8):1911-22. PMID: 17646407.
    Citations: 38     Fields:    Translation:AnimalsCells
  119. Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U. Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007 Jul-Aug; 6(4):269-76. PMID: 17711782.
    Citations: 13     Fields:    Translation:AnimalsCells
  120. Mahmood U, Upadhyay R. Current and Future Imaging Paradigms in Colorectal Cancer. Semin Colon Rectal Surg. 2007 Jun; 18(2):132-138. PMID: 18516215.
  121. Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U. Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice. Radiology. 2007 Jul; 244(1):232-8. PMID: 17507718.
    Citations: 43     Fields:    Translation:AnimalsCells
  122. Sheth RA, Upadhyay R, Weissleder R, Mahmood U. Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging. 2007 May-Jun; 6(3):147-55. PMID: 17532881.
    Citations: 12     Fields:    Translation:Animals
  123. Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R. Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology. 2007 Mar; 242(3):751-8. PMID: 17325064.
    Citations: 44     Fields:    Translation:AnimalsCells
  124. Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B. Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arthritis Rheum. 2007 Jan; 56(1):117-28. PMID: 17195214.
    Citations: 19     Fields:    Translation:AnimalsCells
  125. Mahmood U, Wallace MB. Molecular imaging in gastrointestinal disease. Gastroenterology. 2007 Jan; 132(1):11-4. PMID: 17241854.
    Citations: 9     Fields:    Translation:HumansAnimals
  126. Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U. Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization. Gastrointest Endosc. 2006 Oct; 64(4):589-97. PMID: 16996355.
    Citations: 28     Fields:    Translation:Animals
  127. Kozloff KM, Quinti L, Tung C, Weissleder R, Mahmood U. Non-invasive imaging of osteoclast activity via near-infrared cathepsin-K activatable optical probe. J Musculoskelet Neuronal Interact. 2006 Oct-Dec; 6(4):353. PMID: 17185820.
    Citations: 2     Fields:    Translation:AnimalsCells
  128. Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL. In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice. Neoplasia. 2006 Sep; 8(9):772-80. PMID: 16984734.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  129. Mahmood U. Can a clinically used chemoembolization vehicle improve transgene delivery? Radiology. 2006 Sep; 240(3):619-20. PMID: 16926318.
    Citations:    Fields:    Translation:HumansAnimals
  130. Figueiredo JL, Alencar H, Weissleder R, Mahmood U. Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer. Int J Cancer. 2006 Jun 01; 118(11):2672-7. PMID: 16380983.
    Citations: 25     Fields:    Translation:HumansAnimals
  131. Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK. N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption. Mol Cell Biol. 2006 Jun; 26(11):4185-200. PMID: 16705170.
    Citations: 13     Fields:    Translation:AnimalsCells
  132. Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Jänne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK. The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell. 2006 Jun; 9(6):485-95. PMID: 16730237.
    Citations: 170     Fields:    Translation:HumansAnimalsCells
  133. Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A. 2006 Apr 11; 103(15):5947-52. PMID: 16585505.
    Citations: 256     Fields:    Translation:Animals
  134. Tréhin R, Figueiredo JL, Pittet MJ, Weissleder R, Josephson L, Mahmood U. Fluorescent nanoparticle uptake for brain tumor visualization. Neoplasia. 2006 Apr; 8(4):302-11. PMID: 16756722.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  135. Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C. Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006 Mar; 7(3):284-92. PMID: 16444258.
    Citations: 81     Fields:    Translation:AnimalsCells
  136. Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC. Identification of the target self-antigens in reperfusion injury. J Exp Med. 2006 Jan 23; 203(1):141-52. PMID: 16390934.
    Citations: 93     Fields:    Translation:Animals
  137. Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006 Jan; 17(1):20-30. PMID: 16409122.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  138. Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X. Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery. Hum Gene Ther. 2005 Dec; 16(12):1367-76. PMID: 16390268.
    Citations:    Fields:    Translation:AnimalsCells
  139. Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U. A novel mouse model for segmental orthotopic colon cancer. Int J Cancer. 2005 Nov 10; 117(3):335-9. PMID: 15900588.
    Citations: 14     Fields:    Translation:Animals
  140. Alencar H, Mahmood U, Kawano Y, Hirata T, Weissleder R. Novel multiwavelength microscopic scanner for mouse imaging. Neoplasia. 2005 Nov; 7(11):977-83. PMID: 16331883.
    Citations: 29     Fields:    Translation:Animals
  141. Kim YR, Yudina A, Figueiredo J, Reichardt W, Hu-Lowe D, Petrovsky A, Kang HW, Torres D, Mahmood U, Weissleder R, Bogdanov AA. Detection of early antiangiogenic effects in human colon adenocarcinoma xenografts: in vivo changes of tumor blood volume in response to experimental VEGFR tyrosine kinase inhibitor. Cancer Res. 2005 Oct 15; 65(20):9253-60. PMID: 16230386.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  142. Pivovarov M, Bhandary G, Mahmood U, Zahlmann G, Naraghi M, Weissleder R. MIPortal: a high capacity server for molecular imaging research. Mol Imaging. 2005 Oct-Dec; 4(4):425-31. PMID: 16285904.
    Citations:    Fields:    
  143. Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D. Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes. J Clin Invest. 2005 Sep; 115(9):2454-61. PMID: 16110329.
    Citations: 24     Fields:    Translation:HumansAnimals
  144. Mahmood U, Josephson L. Molecular MR Imaging Probes. Proc IEEE Inst Electr Electron Eng. 2005 Apr; 93(4):800-808. PMID: 19194516.
  145. Chen WT, Mahmood U, Weissleder R, Tung CH. Arthritis imaging using a near-infrared fluorescence folate-targeted probe. Arthritis Res Ther. 2005; 7(2):R310-7. PMID: 15743478.
    Citations: 45     Fields:    Translation:AnimalsCells
  146. Wunder A, Schellenberger E, Mahmood U, Bogdanov A, Müller-Ladner U, Weissleder R, Josephson L. Methotrexate-induced accumulation of fluorescent annexin V in collagen-induced arthritis. Mol Imaging. 2005 Jan-Mar; 4(1):1-6. PMID: 15967121.
    Citations: 4     Fields:    Translation:Animals
  147. Mahmood U. Can MR imaging be used to track delivery of intravascularly administered stem cells? Radiology. 2004 Dec; 233(3):625-6. PMID: 15564396.
    Citations:    Fields:    Translation:Animals
  148. Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R. Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Res. 2004 Sep 01; 64(17):6247-51. PMID: 15342411.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  149. Denis MC, Mahmood U, Benoist C, Mathis D, Weissleder R. Imaging inflammation of the pancreatic islets in type 1 diabetes. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12634-9. PMID: 15304647.
    Citations: 55     Fields:    Translation:AnimalsCells
  150. Wunder A, Tung CH, Müller-Ladner U, Weissleder R, Mahmood U. In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arthritis Rheum. 2004 Aug; 50(8):2459-65. PMID: 15334458.
    Citations: 54     Fields:    Translation:Animals
  151. Mahmood U. Near infrared optical applications in molecular imaging. Earlier, more accurate assessment of disease presence, disease course, and efficacy of disease treatment. IEEE Eng Med Biol Mag. 2004 Jul-Aug; 23(4):58-66. PMID: 15508386.
    Citations: 6     Fields:    Translation:HumansAnimals
  152. Funovics MA, Weissleder R, Mahmood U. Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology. 2004 Jun; 231(3):659-66. PMID: 15163807.
    Citations: 20     Fields:    Translation:AnimalsCells
  153. Kircher MF, Mahmood U, King RS, Weissleder R, Josephson L. A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation. Cancer Res. 2003 Dec 01; 63(23):8122-5. PMID: 14678964.
    Citations: 123     Fields:    Translation:AnimalsCells
  154. Funovics MA, Alencar H, Su HS, Khazaie K, Weissleder R, Mahmood U. Miniaturized multichannel near infrared endoscope for mouse imaging. Mol Imaging. 2003 Oct; 2(4):350-7. PMID: 14717334.
    Citations: 25     Fields:    Translation:Animals
  155. Mahmood U, Weissleder R. Near-infrared optical imaging of proteases in cancer. . 2003 May; 2(5):489-96. PMID: 12748311.
    Citations: 66     Translation:HumansAnimals
  156. Josephson L, Mahmood U, Wunderbaldinger P, Tang Y, Weissleder R. Pan and sentinel lymph node visualization using a near-infrared fluorescent probe. Mol Imaging. 2003 Jan; 2(1):18-23. PMID: 12926234.
    Citations: 10     Fields:    Translation:Animals
  157. Schellingerhout D, Accorsi R, Mahmood U, Idoine J, Lanza RC, Weissleder R. Coded aperture nuclear scintigraphy: a novel small animal imaging technique. Mol Imaging. 2002 Oct; 1(4):344-53. PMID: 12926230.
    Citations: 3     Fields:    Translation:AnimalsCells
  158. Mahmood U, Tung CH, Tang Y, Weissleder R. Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice. Radiology. 2002 Aug; 224(2):446-51. PMID: 12147841.
    Citations: 7     Fields:    Translation:AnimalsCells
  159. Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R. In vivo imaging of proteolytic activity in atherosclerosis. Circulation. 2002 Jun 11; 105(23):2766-71. PMID: 12057992.
    Citations: 106     Fields:    Translation:AnimalsCells
  160. Mahmood U, Weissleder R. Some tools for molecular imaging. Acad Radiol. 2002 Jun; 9(6):629-31. PMID: 12061735.
    Citations: 2     Fields:    Translation:Animals
  161. Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R. Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes. Bioconjug Chem. 2002 May-Jun; 13(3):554-60. PMID: 12009946.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  162. Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D. Arthritis critically dependent on innate immune system players. Immunity. 2002 Feb; 16(2):157-68. PMID: 11869678.
    Citations: 252     Fields:    Translation:AnimalsCells
  163. Bremer C, Bredow S, Mahmood U, Weissleder R, Tung CH. Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model. Radiology. 2001 Nov; 221(2):523-9. PMID: 11687699.
    Citations: 89     Fields:    Translation:Animals
  164. Weissleder R, Mahmood U. Molecular imaging. Radiology. 2001 May; 219(2):316-33. PMID: 11323453.
    Citations: 288     Fields:    Translation:HumansAnimals
  165. Bremer C, Ntziachristos V, Mahmood U, Tung CH, Weissleder R. [Progress in optical imaging]. Radiologe. 2001 Feb; 41(2):131-7. PMID: 11253098.
    Citations: 2     Fields:    Translation:HumansAnimals
  166. Tung CH, Mahmood U, Bredow S, Weissleder R. In vivo imaging of proteolytic enzyme activity using a novel molecular reporter. Cancer Res. 2000 Sep 01; 60(17):4953-8. PMID: 10987312.
    Citations: 81     Fields:    Translation:AnimalsCells
  167. Weissleder R, Moore A, Mahmood U, Bhorade R, Benveniste H, Chiocca EA, Basilion JP. In vivo magnetic resonance imaging of transgene expression. Nat Med. 2000 Mar; 6(3):351-5. PMID: 10700241.
    Citations: 161     Fields:    Translation:AnimalsCells
  168. Mahmood U, Tung CH, Bogdanov A, Weissleder R. Near-infrared optical imaging of protease activity for tumor detection. Radiology. 1999 Dec; 213(3):866-70. PMID: 10580968.
    Citations: 64     Fields:    Translation:HumansAnimalsCells
  169. Tung CH, Bredow S, Mahmood U, Weissleder R. Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging. Bioconjug Chem. 1999 Sep-Oct; 10(5):892-6. PMID: 10502358.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  170. Weissleder R, Tung CH, Mahmood U, Bogdanov A. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol. 1999 Apr; 17(4):375-8. PMID: 10207887.
    Citations: 405     Fields:    Translation:HumansAnimalsCells
  171. Street JC, Szwergold BS, Matei C, Kappler F, Mahmood U, Brown TR, Koutcher JA. Study of the metabolism of choline and phosphatidylcholine in tumors in vivo using phosphonium-choline. Magn Reson Med. 1997 Nov; 38(5):769-75. PMID: 9358451.
    Citations: 3     Fields:    Translation:Animals
  172. Mahmood U, Street JC, Matei C, Ballon D, Martin DS, Koutcher JA. In vivo detection by 31P NMR of pentose phosphate pathway block secondary to biochemical modulation. NMR Biomed. 1996 May; 9(3):114-20. PMID: 8892397.
    Citations: 1     Fields:    Translation:AnimalsCells
  173. Street JC, Mahmood U, Ballon D, Alfieri AA, Koutcher JA. 13C and 31P NMR investigation of effect of 6-aminonicotinamide on metabolism of RIF-1 tumor cells in vitro. J Biol Chem. 1996 Feb 23; 271(8):4113-9. PMID: 8626749.
    Citations: 7     Fields:    Translation:AnimalsCells
  174. Mahmood U, Koutcher JA. Magnetic resonance spectroscopy and imaging in radiology. Med Phys. 1995 Nov; 22(11 Pt 2):1935-41. PMID: 8587547.
    Citations:    Fields:    Translation:HumansAnimals
  175. Street JC, Mahmood U, Matei C, Koutcher JA. In vivo and in vitro studies of cyclophosphamide chemotherapy in a mouse mammary carcinoma by 31P NMR spectroscopy. NMR Biomed. 1995 Jun; 8(4):149-58. PMID: 8771089.
    Citations: 4     Fields:    Translation:Animals
  176. Mahmood U, Alfieri AA, Ballon D, Traganos F, Koutcher JA. In vitro and in vivo 31P nuclear magnetic resonance measurements of metabolic changes post radiation. Cancer Res. 1995 Mar 15; 55(6):1248-54. PMID: 7882317.