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Umar Mahmood, M.D., Ph.D.

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Overview

Mentoring
A Real-Time Method for Quantitative Catheter-Based Fluorescence Molecular Imaging
Summer, 06/01/05 - 09/01/05

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK123143 (MAHMOOD, UMAR) Sep 4, 2020 - May 31, 2024
    NIH
    Granzyme B PET imaging as a marker of inflammatory bowel disease activity
    Role: Principal Investigator
  2. R01CA211223 (MAHMOOD, UMAR) Dec 1, 2017 - Nov 30, 2022
    NIH
    Quantitative HER3 PET Imaging for Assessing Resistance and Guiding Therapy
    Role: Principal Investigator
  3. R01CA214744 (MAHMOOD, UMAR) Aug 1, 2017 - Jul 31, 2022
    NIH
    Cytotoxic lymphocyte function PET imaging to predict cancer immunotherapy response
    Role: Principal Investigator
  4. U01CA202934 (MAHMOOD, UMAR) Mar 2, 2017 - Jun 30, 2022
    NIH
    Optical and electromagnetic tracking guidance for hepatic interventions
    Role: Principal Investigator
  5. S10OD018004 (MAHMOOD, UMAR) Apr 15, 2014 - Apr 14, 2016
    NIH
    MicroPET-MR scanner for preclinical molecular imaging
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Haj-Mirzaian A, Mahmood U, Heidari P. Targeted Molecular Imaging as a Biomarker in Urologic Oncology. Urol Clin North Am. 2023 Feb; 50(1):115-131. PMID: 36424076.
    Citations:    Fields:    Translation:Humans
  2. Wang Y, Yee A, Bernstein Z, O'Donnell E, Raje N, Mahmood U. Carbon-11-Labelled Methionine PET/CT in Patients With FDG-Occult Multiple Myeloma: A Prospective Pilot Study. AJR Am J Roentgenol. 2022 Nov 16. PMID: 36382911.
    Citations:    Fields:    
  3. O'Shea A, Iravani A, Saboury B, Jadvar H, Catalano O, Mahmood U, Heidari P. Integrating Theranostics Into Patient Care Pathways: AJR Expert Panel Narrative Review. AJR Am J Roentgenol. 2022 Nov 02. PMID: 36321986.
    Citations:    Fields:    
  4. Esfahani SA, de Aguiar Ferreira C, Rotile NJ, Ataeinia B, Krishna S, Catalano OA, Caravan P, Yen YF, Heidari P, Mahmood U. HER3 PET Imaging Predicts Response to Pan Receptor Tyrosine Kinase Inhibition Therapy in Gastric Cancer. Mol Imaging Biol. 2022 Aug 12. PMID: 35962301.
    Citations: 1     Fields:    
  5. Mahmood UF, Skinner GJ. Fifteen-minute consultation on excluding cardiac causes of chest pain. Arch Dis Child Educ Pract Ed. 2022 Aug 11. PMID: 35953268.
    Citations:    Fields:    
  6. de Aguiar Ferreira C, Heidari P, Ataeinia B, Sinevici N, Granito A, Kumar HM, Wehrenberg-Klee E, Mahmood U. Immune Checkpoint Inhibitor-Mediated Cancer Theranostics with Radiolabeled Anti-Granzyme B Peptide. Pharmaceutics. 2022 Jul 13; 14(7). PMID: 35890355; PMCID: PMC9325142.
    Citations:    
  7. Esfahani SA, Callahan C, Rotile NJ, Heidari P, Mahmood U, Caravan PD, Grant AK, Yen YF. Hyperpolarized [1-13C]Pyruvate Magnetic Resonance Spectroscopic Imaging for Evaluation of Early Response to Tyrosine Kinase Inhibition Therapy in Gastric Cancer. Mol Imaging Biol. 2022 10; 24(5):769-779. PMID: 35467249; PMCID: PMC9588528.
    Citations:    Fields:    
  8. Furtado FS, Wu MZ, Esfahani SA, Ferrone CR, Blaszkowsky LS, Clark JW, Ryan DP, Goyal L, Franses JW, Wo JY, Hong TS, Qadan M, Tanabe KK, Weekes CD, Cusack JC, Crafa F, Mahmood U, Anderson MA, Mojtahed A, Hahn PF, Caravan P, Kilcoyne A, Vangel M, Striar RR, Rosen BR, Catalano OA. Positron Emission Tomography/Magnetic Resonance Imaging Versus the Standard of Care Imaging in the Diagnosis of Peritoneal Carcinomatosis. Ann Surg. 2022 Feb 17. PMID: 35185121.
    Citations: 1     Fields:    
  9. Ferreira CA, Heidari P, Ataeinia B, Sinevici N, Sise ME, Colvin RB, Wehrenberg-Klee E, Mahmood U. Non-invasive Detection of Immunotherapy-Induced Adverse Events. Clin Cancer Res. 2021 10 01; 27(19):5353-5364. PMID: 34253581; PMCID: PMC8752648.
    Citations: 1     Fields:    Translation:HumansAnimals
  10. Zhang C, O'Shea A, Parente CA, Amorim BJ, Caravan P, Ferrone CR, Blaszkowsky LS, Soricelli A, Salvatore M, Groshar D, Bernstine H, Domachevsky L, Canamaque LG, Umutlu L, Ken H, Catana C, Mahmood U, Catalano OA. Evaluation of the Diagnostic Performance of Positron Emission Tomography/Magnetic Resonance for the Diagnosis of Liver Metastases. Invest Radiol. 2021 10 01; 56(10):621-628. PMID: 33813576.
    Citations: 1     Fields:    Translation:Humans
  11. Mahmood UF, Durairaj S. Patent ductus arteriosus-related endocarditis: not just a theoretical risk. BMJ Case Rep. 2021 Jun 22; 14(6). PMID: 34158324.
    Citations:    Fields:    Translation:Humans
  12. Wehrenberg-Klee E, Sinevici N, Nesti S, Kalomeris T, Austin E, Larimer B, Mahmood U. HER3 PET Imaging Identifies Dynamic Changes in HER3 in Response to HER2 Inhibition with Lapatinib. Mol Imaging Biol. 2021 12; 23(6):930-940. PMID: 34101105; PMCID: PMC8578458.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  13. de Ruiter QMB, Xu S, Li M, Pritchard WF, Starost MF, Filie A, Mikhail AS, Mauda-Havakuk M, Esparza-Trujillo JA, Bakhutashvili I, Heidari P, Mahmood U, Karanian JW, Wood BJ. Electromagnetic Tracking and Optical Molecular Imaging Guidance for Liver Biopsy and Point-of-Care Tissue Assessment in Phantom and Woodchuck Hepatocellular Carcinoma. Cardiovasc Intervent Radiol. 2021 Sep; 44(9):1439-1447. PMID: 34021380; PMCID: PMC8384721.
    Citations:    Fields:    Translation:Animals
  14. Husseini JS, Amorim BJ, Torrado-Carvajal A, Prabhu V, Groshar D, Umutlu L, Herrmann K, Cañamaque LG, Garzón JRG, Palmer WE, Heidari P, Shih TT, Sosna J, Matushita C, Cerci J, Queiroz M, Muglia VF, Nogueira-Barbosa MH, Borra RJH, Kwee TC, Glaudemans AWJM, Evangelista L, Salvatore M, Cuocolo A, Soricelli A, Herold C, Laghi A, Mayerhoefer M, Mahmood U, Catana C, Daldrup-Link HE, Rosen B, Catalano OA. An international expert opinion statement on the utility of PET/MR for imaging of skeletal metastases. Eur J Nucl Med Mol Imaging. 2021 05; 48(5):1522-1537. PMID: 33619599; PMCID: PMC8240455.
    Citations: 1     Fields:    Translation:Humans
  15. Biondetti P, Vangel MG, Lahoud RM, Furtado FS, Rosen BR, Groshar D, Canamaque LG, Umutlu L, Zhang EW, Mahmood U, Digumarthy SR, Shepard JO, Catalano OA. PET/MRI assessment of lung nodules in primary abdominal malignancies: sensitivity and outcome analysis. Eur J Nucl Med Mol Imaging. 2021 06; 48(6):1976-1986. PMID: 33415433.
    Citations: 3     Fields:    Translation:Humans
  16. Tan BS, Dunnick NR, Gangi A, Goergen S, Jin ZY, Neri E, Nomura CH, Pitcher RD, Yee J, Mahmood U. RSNA International Trends: A Global Perspective on the COVID-19 Pandemic and Radiology in Late 2020. Radiology. 2021 04; 299(1):E193-E203. PMID: 33289616; PMCID: PMC7734846.
    Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
  17. Sinevici N, Ataeinia B, Zehnder V, Lin K, Grove L, Heidari P, Mahmood U. HER3 Differentiates Basal From Claudin Type Triple Negative Breast Cancer and Contributes to Drug and Microenvironmental Induced Resistance. Front Oncol. 2020; 10:554704. PMID: 33330026.
    Citations: 1     
  18. Silva CF, Elizondo-Rojas G, Atalabi O, Karçaaltincaba M, Morana G, Mahmood U. RSNA Committee on International Radiology Education: 25 Years of Global Education Outreach. Radiographics. 2020 Nov-Dec; 40(7):1938-1952. PMID: 33136478.
    Citations:    Fields:    Translation:Humans
  19. Catalano OA, Lee SI, Parente C, Cauley C, Furtado FS, Striar R, Soricelli A, Salvatore M, Li Y, Umutlu L, Cañamaque LG, Groshar D, Mahmood U, Blaszkowsky LS, Ryan DP, Clark JW, Wo J, Hong TS, Kunitake H, Bordeianou L, Berger D, Ricciardi R, Rosen B. Improving staging of rectal cancer in the pelvis: the role of PET/MRI. Eur J Nucl Med Mol Imaging. 2021 04; 48(4):1235-1245. PMID: 33034673.
    Citations: 11     Fields:    Translation:Humans
  20. Xu J, Higgins MJ, Tolaney SM, Come SE, Smith MR, Fornier M, Mahmood U, Baselga J, Yeap BY, Chabner BA, Isakoff SJ. A Phase II Trial of Cabozantinib in Hormone Receptor-Positive Breast Cancer with Bone Metastases. Oncologist. 2020 08; 25(8):652-660. PMID: 32463152.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  21. LaSalle T, Austin EE, Rigney G, Wehrenberg-Klee E, Nesti S, Larimer B, Mahmood U. Granzyme B PET imaging of immune-mediated tumor killing as a tool for understanding immunotherapy response. J Immunother Cancer. 2020 05; 8(1). PMID: 32461343.
    Citations: 10     Fields:    Translation:HumansAnimals
  22. Tam J, Pilozzi A, Mahmood U, Huang X. Simultaneous Monitoring of Multi-Enzyme Activity and Concentration in Tumor Using a Triply Labeled Fluorescent In Vivo Imaging Probe. Int J Mol Sci. 2020 Apr 27; 21(9). PMID: 32349205.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  23. Ferrone C, Goyal L, Qadan M, Gervais D, Sahani DV, Zhu AX, Hong TS, Blaszkowsky LS, Tanabe KK, Vangel M, Amorim BJ, Wo JY, Mahmood U, Pandharipande PV, Catana C, Duenas VP, Collazo YQ, Canamaque LG, Domachevsky L, Bernstine HH, Groshar D, Shih TT, Li Y, Herrmann K, Umutlu L, Rosen BR, Catalano OA. Management implications of fluorodeoxyglucose positron emission tomography/magnetic resonance in untreated intrahepatic cholangiocarcinoma. Eur J Nucl Med Mol Imaging. 2020 07; 47(8):1871-1884. PMID: 31705172.
    Citations: 8     Fields:    Translation:Humans
  24. Esfahani SA, Heidari P, Kucherlapati MH, Ferrer JM, Kucherlapati RS, Mahmood U. Optical imaging with a novel cathepsin-activatable probe for enhanced detection of colorectal cancer. Am J Nucl Med Mol Imaging. 2019; 9(5):230-242. PMID: 31772821; PMCID: PMC6872479.
    Citations: 5     
  25. Amorim BJ, Hong TS, Blaszkowsky LS, Ferrone CR, Berger DL, Bordeianou LG, Ricciardi R, Clark JW, Ryan DP, Wo JY, Qadan M, Vangel M, Umutlu L, Groshar D, Cañamaques LG, Gervais DA, Mahmood U, Rosen BR, Catalano OA. Clinical impact of PET/MR in treated colorectal cancer patients. Eur J Nucl Med Mol Imaging. 2019 Oct; 46(11):2260-2269. PMID: 31359108.
    Citations: 10     Fields:    Translation:Humans
  26. Gilbert TM, Zürcher NR, Catanese MC, Tseng CJ, Di Biase MA, Lyall AE, Hightower BG, Parmar AJ, Bhanot A, Wu CJ, Hibert ML, Kim M, Mahmood U, Stufflebeam SM, Schroeder FA, Wang C, Roffman JL, Holt DJ, Greve DN, Pasternak O, Kubicki M, Wey HY, Hooker JM. Neuroepigenetic signatures of age and sex in the living human brain. Nat Commun. 2019 07 03; 10(1):2945. PMID: 31270332.
    Citations: 12     Fields:    Translation:Humans
  27. Wang Y, Ayres KL, Goldman DA, Dickler MN, Bardia A, Mayer IA, Winer E, Fredrickson J, Arteaga CL, Baselga J, Manning HC, Mahmood U, Ulaner GA. Correction: 18F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials. Clin Cancer Res. 2019 Feb 15; 25(4):1435. PMID: 30770494.
    Citations: 1     Fields:    
  28. Andriole GL, Kostakoglu L, Chau A, Duan F, Mahmood U, Mankoff DA, Schuster DM, Siegel BA. The Impact of Positron Emission Tomography with 18F-Fluciclovine on the Treatment of Biochemical Recurrence of Prostate Cancer: Results from the LOCATE Trial. J Urol. 2019 02; 201(2):322-331. PMID: 30179618; PMCID: PMC7007765.
    Citations: 39     Fields:    Translation:HumansCTClinical Trials
  29. Zadra G, Ribeiro CF, Chetta P, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y, Tyekucheva S, Bastos DC, Tchaicha J, Lawney B, Uo T, D'Anello L, Csibi A, Kalekar R, Larimer B, Ellis L, Butler LM, Morrissey C, McGovern K, Palombella VJ, Kutok JL, Mahmood U, Bosari S, Adams J, Peluso S, Dehm SM, Plymate SR, Loda M. Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2019 01 08; 116(2):631-640. PMID: 30578319; PMCID: PMC6329966.
    Citations: 78     Fields:    Translation:HumansAnimalsCells
  30. Larimer BM, Bloch E, Nesti S, Austin EE, Wehrenberg-Klee E, Boland G, Mahmood U. The Effectiveness of Checkpoint Inhibitor Combinations and Administration Timing Can Be Measured by Granzyme B PET Imaging. Clin Cancer Res. 2019 02 15; 25(4):1196-1205. PMID: 30327313; PMCID: PMC6377844.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  31. Ferry-Galow KV, Datta V, Makhlouf HR, Wright J, Wood BJ, Levy E, Pisano ED, Tam AL, Lee SI, Mahmood U, Rubinstein LV, Doroshow JH, Chen AP. What Can Be Done to Improve Research Biopsy Quality in Oncology Clinical Trials? J Oncol Pract. 2018 Oct 04; JOP1800092. PMID: 30285529.
    Citations: 15     Fields:    
  32. Catalano O, Kilcoyne A, Signore A, Mahmood U, Rosen B. Lower Gastrointestinal Tract Applications of PET/Computed Tomography and PET/MR Imaging. Radiol Clin North Am. 2018 Sep; 56(5):821-834. PMID: 30119776.
    Citations: 3     Fields:    Translation:Humans
  33. Hanna GJ, Supplee JG, Kuang Y, Mahmood U, Lau CJ, Haddad RI, Jänne PA, Paweletz CP. Plasma HPV cell-free DNA monitoring in advanced HPV-associated oropharyngeal cancer. Ann Oncol. 2018 09 01; 29(9):1980-1986. PMID: 30010779.
    Citations: 25     Fields:    Translation:HumansCells
  34. Catalano OA, Umutlu L, Fuin N, Hibert ML, Scipioni M, Pedemonte S, Vangel M, Catana AM, Herrmann K, Nensa F, Groshar D, Mahmood U, Rosen BR, Catana C. Comparison of the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo). Eur J Nucl Med Mol Imaging. 2018 11; 45(12):2147-2154. PMID: 29998420.
    Citations: 4     Fields:    Translation:Humans
  35. Wang Y, Rapalino O, Heidari P, Loeffler J, Shih HA, Oh K, Mahmood U. C11 Methionine PET (MET-PET) Imaging of Glioblastoma for Detecting Postoperative Residual Disease and Response to Chemoradiation Therapy. Int J Radiat Oncol Biol Phys. 2018 11 15; 102(4):1024-1028. PMID: 29913253; PMCID: PMC7336810.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  36. Larimer BM, Dubois F, Bloch E, Nesti S, Placzek M, Zadra G, Hooker JM, Loda M, Mahmood U. Specific 18F-FDHT Accumulation in Human Prostate Cancer Xenograft Murine Models Is Facilitated by Prebinding to Sex Hormone-Binding Globulin. J Nucl Med. 2018 10; 59(10):1538-1543. PMID: 29853654.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  37. Heidari P, Kunawudhi A, Martinez-Quintanilla J, Szretter A, Shah K, Mahmood U. Somatostatin receptor type 2 as a radiotheranostic PET reporter gene for oncologic interventions. Theranostics. 2018; 8(12):3380-3391. PMID: 29930736.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  38. Li Q, Xiang F, Lin X, Grajo JR, Yang L, Xu Y, Duan Y, Vyas U, Harisinghani M, Mahmood U, Samir AE. The Role of Imaging in Prostate Cancer Care Pathway: Novel Approaches to Urologic Management Challenges Along 10 Imaging Touch Points. Urology. 2018 Sep; 119:23-31. PMID: 29730256.
    Citations: 3     Fields:    Translation:Humans
  39. Larimer BM, Phelan N, Wehrenberg-Klee E, Mahmood U. Phage Display Selection, In Vitro Characterization, and Correlative PET Imaging of a Novel HER3 Peptide. Mol Imaging Biol. 2018 04; 20(2):300-308. PMID: 28733706.
    Citations: 8     Fields:    Translation:AnimalsCells
  40. Catalano OA, Wu V, Mahmood U, Signore A, Vangel M, Soricelli A, Salvatore M, Gervais D, Rosen BR. Diagnostic performance of PET/MR in the evaluation of active inflammation in Crohn disease. Am J Nucl Med Mol Imaging. 2018; 8(1):62-69. PMID: 29531862; PMCID: PMC5840324.
    Citations: 10     
  41. Jadvar H, Chen X, Cai W, Mahmood U. Radiotheranostics in Cancer Diagnosis and Management. Radiology. 2018 02; 286(2):388-400. PMID: 29356634; PMCID: PMC5790308.
    Citations: 25     Fields:    Translation:Humans
  42. Wang Y, Yee AJ, Sirard C, Landau S, Raje N, Mahmood U. Sodium fluoride PET imaging as a quantitative pharmacodynamic biomarker for bone homeostasis during anti-DKK1 therapy for multiple myeloma. Blood Cancer J. 2017 10 06; 7(10):e615. PMID: 28984867.
    Citations: 4     Fields:    Translation:Humans
  43. Collier TL, Normandin MD, Stephenson NA, Livni E, Liang SH, Wooten DW, Esfahani SA, Stabin MG, Mahmood U, Chen J, Wang W, Maresca K, Waterhouse RN, El Fakhri G, Richardson P, Vasdev N. Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib. Nat Commun. 2017 06 08; 8:15761. PMID: 28594000; PMCID: PMC5472746.
    Citations: 14     Fields:    Translation:HumansAnimals
  44. Catalano OA, Daye D, Signore A, Iannace C, Vangel M, Luongo A, Catalano M, Filomena M, Mansi L, Soricelli A, Salvatore M, Fuin N, Catana C, Mahmood U, Rosen BR. Staging performance of whole-body DWI, PET/CT and PET/MRI in invasive ductal carcinoma of the breast. Int J Oncol. 2017 Jul; 51(1):281-288. PMID: 28535000.
    Citations: 20     Fields:    Translation:Humans
  45. Holliday EB, Kuban DA, Levy LB, Bolukbasi Y, Master P, Choi S, Nguyen Q, McGuire SE, Mahmood U, Frank SJ, Hoffman KE. Select men benefit from androgen deprivation therapy delivered with salvage radiation therapy after prostatectomy. Prostate Cancer Prostatic Dis. 2017 12; 20(4):389-394. PMID: 28462945.
    Citations: 1     Fields:    Translation:Humans
  46. Larimer BM, Wehrenberg-Klee E, Dubois F, Mehta A, Kalomeris T, Flaherty K, Boland G, Mahmood U. Granzyme B PET Imaging as a Predictive Biomarker of Immunotherapy Response. Cancer Res. 2017 05 01; 77(9):2318-2327. PMID: 28461564; PMCID: PMC5474226.
    Citations: 107     Fields:    Translation:HumansAnimalsCells
  47. Esfahani SA, Salcedo S, Heidari P, Catalano OA, Pauplis R, Hesterman J, Kronauge JF, Mahmood U. A phase one, single-dose, open-label, clinical safety and PET/MR imaging study of 68Ga-DOTATOC in healthy volunteers. Am J Nucl Med Mol Imaging. 2017; 7(2):53-62. PMID: 28533937; PMCID: PMC5435611.
    Citations: 3     
  48. Catalano OA, Coutinho AM, Sahani DV, Vangel MG, Gee MS, Hahn PF, Witzel T, Soricelli A, Salvatore M, Catana C, Mahmood U, Rosen BR, Gervais D. Colorectal cancer staging: comparison of whole-body PET/CT and PET/MR. Abdom Radiol (NY). 2017 04; 42(4):1141-1151. PMID: 27891551.
    Citations: 10     Fields:    Translation:Humans
  49. Catalano OA, Horn GL, Signore A, Iannace C, Lepore M, Vangel M, Luongo A, Catalano M, Lehman C, Salvatore M, Soricelli A, Catana C, Mahmood U, Rosen BR. PET/MR in invasive ductal breast cancer: correlation between imaging markers and histological phenotype. Br J Cancer. 2017 Mar 28; 116(7):893-902. PMID: 28208155; PMCID: PMC5379139.
    Citations: 15     Fields:    Translation:Humans
  50. Catalano OA, Masch WR, Catana C, Mahmood U, Sahani DV, Gee MS, Menezes L, Soricelli A, Salvatore M, Gervais D, Rosen BR. An overview of PET/MR, focused on clinical applications. Abdom Radiol (NY). 2017 02; 42(2):631-644. PMID: 27624499.
    Citations: 6     Fields:    Translation:Humans
  51. Wang Y, Ayres KL, Goldman DA, Dickler MN, Bardia A, Mayer IA, Winer E, Fredrickson J, Arteaga CL, Baselga J, Manning HC, Mahmood U, Ulaner GA. 18F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials. Clin Cancer Res. 2017 Jun 15; 23(12):3053-3060. PMID: 28011460.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  52. Qian ZR, Li T, Ter-Minassian M, Yang J, Chan JA, Brais LK, Masugi Y, Thiaglingam A, Brooks N, Nishihara R, Bonnemarie M, Masuda A, Inamura K, Kim SA, Mima K, Sukawa Y, Dou R, Lin X, Christiani DC, Schmidlin F, Fuchs CS, Mahmood U, Ogino S, Kulke MH. Association Between Somatostatin Receptor Expression and Clinical Outcomes in Neuroendocrine Tumors. Pancreas. 2016 11; 45(10):1386-1393. PMID: 27622342.
    Citations: 43     Fields:    Translation:Humans
  53. Kilcoyne A, Harisinghani MG, Mahmood U. Prostate Cancer Imaging and Therapy: Potential Role of Nanoparticles. J Nucl Med. 2016 Oct; 57(Suppl 3):105S-110S. PMID: 27694162.
    Citations: 2     Fields:    Translation:HumansAnimals
  54. Wang Y, Oh KS, Loeffler JS, Shih HA, Mahmood U. C11 Methionine Positron Emission Tomography (MET-PET) Imaging of Glioblastoma for Detecting Postoperative Residual Disease and Response to Chemoradiation Therapy. Int J Radiat Oncol Biol Phys. 2016 Oct 1; 96(2S):E93. PMID: 27675505.
    Citations:    
  55. Esfahani SA, Heidari P, Kim SA, Ogino S, Mahmood U. Optical Imaging of Mesenchymal Epithelial Transition Factor (MET) for Enhanced Detection and Characterization of Primary and Metastatic Hepatic Tumors. Theranostics. 2016; 6(12):2028-2038. PMID: 27698938.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  56. Heidari P, Szretter A, Rushford LE, Stevens M, Collier L, Sore J, Hooker J, Mahmood U. Design, construction and testing of a low-cost automated (68)Gallium-labeling synthesis unit for clinical use. Am J Nucl Med Mol Imaging. 2016; 6(3):176-84. PMID: 27508104; PMCID: PMC4965522.
    Citations: 4     
  57. Larimer BM, Wehrenberg-Klee E, Caraballo A, Mahmood U. Quantitative CD3 PET Imaging Predicts Tumor Growth Response to Anti-CTLA-4 Therapy. J Nucl Med. 2016 Oct; 57(10):1607-1611. PMID: 27230929; PMCID: PMC5367446.
    Citations: 54     Fields:    Translation:AnimalsCells
  58. McPartlin AJ, Li XA, Kershaw LE, Heide U, Kerkmeijer L, Lawton C, Mahmood U, Pos F, van As N, van Herk M, Vesprini D, van der Voort van Zyp J, Tree A, Choudhury A. MRI-guided prostate adaptive radiotherapy - A systematic review. Radiother Oncol. 2016 06; 119(3):371-80. PMID: 27162159.
    Citations: 42     Fields:    Translation:Humans
  59. Wehrenberg-Klee E, Turker NS, Heidari P, Larimer B, Juric D, Baselga J, Scaltriti M, Mahmood U. Differential Receptor Tyrosine Kinase PET Imaging for Therapeutic Guidance. J Nucl Med. 2016 09; 57(9):1413-9. PMID: 27081168; PMCID: PMC5093919.
    Citations: 15     Fields:    Translation:HumansCells
  60. Pugmire BS, Guimaraes AR, Lim R, Friedmann AM, Huang M, Ebb D, Weinstein H, Catalano OA, Mahmood U, Catana C, Gee MS. Simultaneous whole body (18)F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging for evaluation of pediatric cancer: Preliminary experience and comparison with (18)F-fluorodeoxyglucose positron emission tomography computed tomography. World J Radiol. 2016 Mar 28; 8(3):322-30. PMID: 27028112; PMCID: PMC4807342.
    Citations: 2     
  61. Sheth RA, Heidari P, Woods K, Chung D, Chan AT, Mahmood U. Pilot Clinical Trial of Indocyanine Green Fluorescence-Augmented Colonoscopy in High Risk Patients. Gastroenterol Res Pract. 2016; 2016:6184842. PMID: 26989406; PMCID: PMC4773548.
    Citations: 1     
  62. Kunawudhi A, Wong AK, Alkasab TK, Mahmood U. Accuracy of FDG-PET/CT for Detection of Incidental Pre-Malignant and Malignant Colonic Lesions - Correlation with Colonoscopic and Histopathologic Findings. Asian Pac J Cancer Prev. 2016; 17(8):4143-7. PMID: 27644675.
    Citations: 2     Fields:    Translation:Humans
  63. Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 2015 Dec 14; 28(6):831-833. PMID: 28843279.
    Citations: 74     Fields:    
  64. Mahmood U. 2015 SNMMI Highlights Lecture: Oncology, Part II. J Nucl Med. 2015 Dec; 56(12):9N-16N. PMID: 26626870.
    Citations:    Fields:    Translation:HumansAnimals
  65. Mahmood U. 2015 SNMMI Highlights Lecture: Oncology, Part I. J Nucl Med. 2015 Nov; 56(11):9N-16N. PMID: 26526798; PMCID: PMC4826777.
    Citations:    Fields:    Translation:HumansAnimals
  66. Wehrenberg-Klee E, Redjal N, Leece A, Turker NS, Heidari P, Shah K, Mahmood U. PET imaging of glioblastoma multiforme EGFR expression for therapeutic decision guidance. Am J Nucl Med Mol Imaging. 2015; 5(4):379-89. PMID: 26269775; PMCID: PMC4529591.
    Citations: 8     
  67. Heidari P, Esfahani SA, Turker NS, Wong G, Wang TC, Rustgi AK, Mahmood U. Imaging of Secreted Extracellular Periostin, an Important Marker of Invasion in the Tumor Microenvironment in Esophageal Cancer. J Nucl Med. 2015 Aug; 56(8):1246-51. PMID: 26069303; PMCID: PMC4826779.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  68. Catalano OA, Nicolai E, Rosen BR, Luongo A, Catalano M, Iannace C, Guimaraes A, Vangel MG, Mahmood U, Soricelli A, Salvatore M. Comparison of CE-FDG-PET/CT with CE-FDG-PET/MR in the evaluation of osseous metastases in breast cancer patients. Br J Cancer. 2015 Apr 28; 112(9):1452-60. PMID: 25871331; PMCID: PMC4453670.
    Citations: 35     Fields:    Translation:Humans
  69. Arvold ND, Heidari P, Kunawudhi A, Sequist LV, Mahmood U. Tumor Hypoxia Response After Targeted Therapy in EGFR-Mutant Non-Small Cell Lung Cancer: Proof of Concept for FMISO-PET. Technol Cancer Res Treat. 2016 Apr; 15(2):234-42. PMID: 25759424; PMCID: PMC4565779.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  70. Leahy AA, Esfahani SA, Foote AT, Hui CK, Rainbow RS, Nakamura DS, Tracey BH, Mahmood U, Zeng L. Analysis of the trajectory of osteoarthritis development in a mouse model by serial near-infrared fluorescence imaging of matrix metalloproteinase activities. Arthritis Rheumatol. 2015 Feb; 67(2):442-53. PMID: 25385707; PMCID: PMC4312249.
    Citations: 12     Fields:    Translation:AnimalsCells
  71. Heidari P, Deng F, Esfahani SA, Leece AK, Shoup TM, Vasdev N, Mahmood U. Pharmacodynamic imaging guides dosing of a selective estrogen receptor degrader. Clin Cancer Res. 2015 Mar 15; 21(6):1340-7. PMID: 25609068; PMCID: PMC4359957.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  72. Gupta S, Mahmood U, Gurung S, Shrestha S, Kushner AL, Nwomeh BC, Charles AG. Burns in Nepal: A population based national assessment. Burns. 2015 Aug; 41(5):1126-32. PMID: 25523087.
    Citations: 13     Fields:    Translation:Humans
  73. Mahmood U. 2014 SNMMI highlights lecture: Oncology. J Nucl Med. 2014 Nov; 55(11):9N-24N. PMID: 25368337; PMCID: PMC4403671.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  74. Sheth RA, Arellano RS, Uppot RN, Samir AE, Goyal L, Zhu AX, Gervais DA, Mahmood U. Prospective trial with optical molecular imaging for percutaneous interventions in focal hepatic lesions. Radiology. 2015 Mar; 274(3):917-26. PMID: 25302707; PMCID: PMC4407559.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  75. Zadra G, Photopoulos C, Tyekucheva S, Heidari P, Weng QP, Fedele G, Liu H, Scaglia N, Priolo C, Sicinska E, Mahmood U, Signoretti S, Birnberg N, Loda M. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014; 6(10):1357. PMID: 25178544.
    Citations:    
  76. Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D. Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):11419-24. PMID: 25049388.
    Citations: 28     Fields:    Translation:AnimalsCells
  77. Turker NS, Heidari P, Kucherlapati R, Kucherlapati M, Mahmood U. An EGFR targeted PET imaging probe for the detection of colonic adenocarcinomas in the setting of colitis. Theranostics. 2014; 4(9):893-903. PMID: 25057314.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  78. Kuruppu D, Brownell AL, Shah K, Mahmood U, Tanabe KK. Molecular imaging with bioluminescence and PET reveals viral oncolysis kinetics and tumor viability. Cancer Res. 2014 Aug 01; 74(15):4111-21. PMID: 24876106.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  79. Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014 Jun 16; 25(6):719-34. PMID: 24856586; PMCID: PMC4180632.
    Citations: 944     Fields:    Translation:HumansAnimalsCells
  80. Habibollahi P, Waldron T, Heidari P, Cho HS, Alcantara D, Josephson L, Wang TC, Rustgi AK, Mahmood U. Fluorescent Nanoparticle Imaging Allows Noninvasive Evaluation of Immune Cell Modulation in Esophageal Dysplasia. Mol Imaging. 2014 May 01; 13(3):7290201400003. PMID: 28650303.
    Citations:    
  81. Sheth RA, Heidari P, Esfahani SA, Wood BJ, Mahmood U. Interventional optical molecular imaging guidance during percutaneous biopsy. Radiology. 2014 Jun; 271(3):770-7. PMID: 24520946; PMCID: PMC4263633.
    Citations: 14     Fields:    Translation:Animals
  82. Zadra G, Photopoulos C, Tyekucheva S, Heidari P, Weng QP, Fedele G, Liu H, Scaglia N, Priolo C, Sicinska E, Mahmood U, Signoretti S, Birnberg N, Loda M. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014 04; 6(4):519-38. PMID: 24497570.
    Citations: 92     Fields:    Translation:HumansAnimalsCells
  83. Habibollahi P, Waldron T, Heidari P, Cho HS, Alcantara D, Josephson L, Wang TC, Rustgi AK, Mahmood U. Fluorescent nanoparticle imaging allows noninvasive evaluation of immune cell modulation in esophageal dysplasia. Mol Imaging. 2014; 13:1-11. PMID: 24824854.
    Citations: 5     Fields:    Translation:AnimalsCells
  84. Heidari P, Wehrenberg-Klee E, Habibollahi P, Yokell D, Kulke M, Mahmood U. Free somatostatin receptor fraction predicts the antiproliferative effect of octreotide in a neuroendocrine tumor model: implications for dose optimization. Cancer Res. 2013 Dec 01; 73(23):6865-73. PMID: 24080280.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  85. Martinez-Quintanilla J, Bhere D, Heidari P, He D, Mahmood U, Shah K. Therapeutic efficacy and fate of bimodal engineered stem cells in malignant brain tumors. Stem Cells. 2013 Aug; 31(8):1706-14. PMID: 23389839.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  86. Kucherlapati MH, Esfahani S, Habibollahi P, Wang J, Still ER, Bronson RT, Mahmood U, Kucherlapati RS. Genotype directed therapy in murine mismatch repair deficient tumors. PLoS One. 2013; 8(7):e68817. PMID: 23935891; PMCID: PMC3720855.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  87. Leece AK, Heidari P, Yokell DL, Mahmood U. A container closure system that allows for greater recovery of radiolabeled peptide compared to the standard borosilicate glass system. Appl Radiat Isot. 2013 Oct; 80:99-102. PMID: 23860127.
    Citations: 3     Fields:    
  88. Esfahani SA, Heidari P, Halpern EF, Hochberg EP, Palmer EL, Mahmood U. Baseline total lesion glycolysis measured with (18)F-FDG PET/CT as a predictor of progression-free survival in diffuse large B-cell lymphoma: a pilot study. Am J Nucl Med Mol Imaging. 2013; 3(3):272-81. PMID: 23638338.
    Citations: 34     
  89. Martin ES, Belmont PJ, Sinnamon MJ, Richard LG, Yuan J, Coffee EM, Roper J, Lee L, Heidari P, Lunt SY, Goel G, Ji X, Xie Z, Xie T, Lamb J, Weinrich SL, VanArsdale T, Bronson RT, Xavier RJ, Vander Heiden MG, Kan JL, Mahmood U, Hung KE. Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation. Clin Cancer Res. 2013 Jun 01; 19(11):2929-40. PMID: 23403635; PMCID: PMC3951107.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  90. Cho H, Alcantara D, Yuan H, Sheth RA, Chen HH, Huang P, Andersson SB, Sosnovik DE, Mahmood U, Josephson L. Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems. ACS Nano. 2013 Mar 26; 7(3):2032-41. PMID: 23373524.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  91. Habibollahi P, van den Berg NS, Kuruppu D, Loda M, Mahmood U. Metformin--an adjunct antineoplastic therapy--divergently modulates tumor metabolism and proliferation, interfering with early response prediction by 18F-FDG PET imaging. J Nucl Med. 2013 Feb; 54(2):252-8. PMID: 23376854.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  92. Wong GS, Habibollahi P, Heidari P, Lee JS, Klein-Szanto AJ, Waldron TJ, Gimotty P, Nakagawa H, Taylor PR, Wang TC, Mahmood U, Rustgi AK. Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice. Gastroenterology. 2013 Feb; 144(2):294-297. PMID: 23085486; PMCID: PMC3624041.
    Citations: 13     Fields:    Translation:HumansAnimals
  93. Saylor PJ, Mahmood U, Kunawudhi A, Smith MR, Palmer EL, Michaelson MD. Multitargeted tyrosine kinase inhibition produces discordant changes between 99mTc-MDP bone scans and other disease biomarkers: analysis of a phase II study of sunitinib for metastatic castration-resistant prostate cancer. J Nucl Med. 2012 Nov; 53(11):1670-5. PMID: 22984218.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  94. Sheth RA, Kunin A, Stangenberg L, Sinnamon M, Hung KE, Kucherlapati R, Mahmood U. In vivo optical molecular imaging of matrix metalloproteinase activity following celecoxib therapy for colorectal cancer. Mol Imaging. 2012 Sep-Oct; 11(5):417-25. PMID: 22954186.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  95. Yokell DL, Leece AK, Lebedev A, Miraghaie R, Ball CE, Zhang J, Kolb H, Elizarov A, Mahmood U. Microfluidic single vessel production of hypoxia tracer 1H-1-(3-[18F]-fluoro-2-hydroxy-propyl)-2-nitro-imidazole ([18F]-FMISO). Appl Radiat Isot. 2012 Oct; 70(10):2313-6. PMID: 22871433.
    Citations: 3     Fields:    
  96. Habibollahi P, Figueiredo JL, Heidari P, Dulak AM, Imamura Y, Bass AJ, Ogino S, Chan AT, Mahmood U. Optical Imaging with a Cathepsin B Activated Probe for the Enhanced Detection of Esophageal Adenocarcinoma by Dual Channel Fluorescent Upper GI Endoscopy. Theranostics. 2012; 2(2):227-34. PMID: 22400064.
    Citations: 18     Fields:    
  97. Quante M, Bhagat G, Abrams JA, Marache F, Good P, Lee MD, Lee Y, Friedman R, Asfaha S, Dubeykovskaya Z, Mahmood U, Figueiredo JL, Kitajewski J, Shawber C, Lightdale CJ, Rustgi AK, Wang TC. Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. Cancer Cell. 2012 Jan 17; 21(1):36-51. PMID: 22264787.
    Citations: 194     Fields:    Translation:AnimalsCells
  98. Mahmood U, Hanlon AL, Koshy M, Buras R, Chumsri S, Tkaczuk KH, Cheston S, Regine W, Feigenberg SJ. Early evidence of increasing national mastectomy rates for the treatment of breast cancer. J Clin Oncol. 2011 Sep 20; 29(27_suppl):136. PMID: 27958139.
    Citations:    
  99. Mahmood U, Morris CG, Neuner GA, Koshy M, Kesmodel S, Buras R, Chumsri S, Bao T, Tkaczuk KH, Feigenberg SJ. Comparing survival with breast-conservation therapy or mastectomy in the management of young women with early-stage breast cancer. J Clin Oncol. 2011 Sep 20; 29(27_suppl):85. PMID: 27958073.
    Citations:    
  100. Chan AT, Baba Y, Shima K, Nosho K, Chung DC, Hung KE, Mahmood U, Madden K, Poss K, Ranieri A, Shue D, Kucherlapati R, Fuchs CS, Ogino S. Cathepsin B expression and survival in colon cancer: implications for molecular detection of neoplasia. Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11):2777-85. PMID: 20833970.
    Citations: 24     Fields:    Translation:Humans
  101. Sheth RA, Mahmood U. Optical molecular imaging and its emerging role in colorectal cancer. Am J Physiol Gastrointest Liver Physiol. 2010 Oct; 299(4):G807-20. PMID: 20595618.
    Citations: 11     Fields:    Translation:Humans
  102. Sheth RA, Maricevich M, Mahmood U. In vivo optical molecular imaging of matrix metalloproteinase activity in abdominal aortic aneurysms correlates with treatment effects on growth rate. Atherosclerosis. 2010 Sep; 212(1):181-7. PMID: 20542274.
    Citations: 23     Fields:    Translation:Animals
  103. Mahmood U. Science to practice: can a targeted nanoparticle be used to image autoimmune nephritis? Radiology. 2010 May; 255(2):309-10. PMID: 20413745.
    Citations: 1     Fields:    Translation:Animals
  104. Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A, Bronson RT, Mahmood U, Kucherlapati R. Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4):1565-70. PMID: 20080688; PMCID: PMC2824379.
    Citations: 116     Fields:    Translation:AnimalsCells
  105. Ventura E, Islam T, Gee MS, Mahmood U, Braschi M, Harisinghani MG. Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT. Clin Imaging. 2010 Jan-Feb; 34(1):20-8. PMID: 20122515.
    Citations: 2     Fields:    Translation:Humans
  106. Mahmood U. Optical molecular imaging approaches in colorectal cancer. Gastroenterology. 2010 Feb; 138(2):419-22. PMID: 20026448; PMCID: PMC2896906.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  107. Sheth RA, Josephson L, Mahmood U. Evaluation and clinically relevant applications of a fluorescent imaging analog to fluorodeoxyglucose positron emission tomography. J Biomed Opt. 2009 Nov-Dec; 14(6):064014. PMID: 20059252.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  108. Wadlow RC, Wittner BS, Finley SA, Bergquist H, Upadhyay R, Finn S, Loda M, Mahmood U, Ramaswamy S. Systems-level modeling of cancer-fibroblast interaction. PLoS One. 2009 Sep 03; 4(9):e6888. PMID: 19727395.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  109. Mahmood U. Science to practice: can an enzyme-sensitive MR contrast agent be used to image inflammation in aneurysms? Radiology. 2009 Sep; 252(3):627-8. PMID: 19717746.
    Citations: 2     Fields:    Translation:Animals
  110. Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U. Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheum. 2009 Aug; 60(8):2314-24. PMID: 19644878; PMCID: PMC3080016.
    Citations: 7     Fields:    Translation:AnimalsCells
  111. Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG. Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2009 Jul 15; 74(4):1207-16. PMID: 19545786.
    Citations: 25     Fields:    Translation:Animals
  112. Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R. Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commun (Camb). 2009 Jul 28; (28):4188-90. PMID: 19585016.
    Citations: 35     Fields:    Translation:Animals
  113. Sheth RA, Tam JM, Maricevich MA, Josephson L, Mahmood U. Quantitative endovascular fluorescence-based molecular imaging through blood of arterial wall inflammation. Radiology. 2009 Jun; 251(3):813-21. PMID: 19474377; PMCID: PMC2687531.
    Citations: 6     Fields:    Translation:Animals
  114. Salthouse CD, Reynolds F, Tam JM, Josephson L, Mahmood U. Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects. Sens Actuators B Chem. 2009 May 06; 138(2):591-597. PMID: 20161242.
    Citations: 4     
  115. Hung KE, Faca V, Song K, Sarracino DA, Richard LG, Krastins B, Forrester S, Porter A, Kunin A, Mahmood U, Haab BB, Hanash SM, Kucherlapati R. Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with intestinal tumorigenesis. Cancer Prev Res (Phila). 2009 Mar; 2(3):224-33. PMID: 19240248.
    Citations: 26     Fields:    Translation:AnimalsCells
  116. Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U. Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model. Gynecol Oncol. 2009 Mar; 112(3):616-22. PMID: 19135233.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  117. Salthouse C, Hildebrand S, Weissleder R, Mahmood U. Design and demonstration of a small-animal up-conversion imager. Opt Express. 2008 Dec 22; 16(26):21731-7. PMID: 19104605.
    Citations: 6     Fields:    Translation:Animals
  118. Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, García-Echeverría C, Weissleder R, Mahmood U, Cantley LC, Wong KK. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med. 2008 Dec; 14(12):1351-6. PMID: 19029981.
    Citations: 672     Fields:    Translation:AnimalsCells
  119. Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK. A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest. 2008 Dec; 118(12):3860-9. PMID: 19033657; PMCID: PMC2579884.
    Citations: 58     Fields:    Translation:AnimalsCells
  120. Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U. Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone. 2009 Feb; 44(2):190-8. PMID: 19007918.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  121. Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK. Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. Clin Cancer Res. 2008 Oct 15; 14(20):6478-86. PMID: 18927287; PMCID: PMC2696122.
    Citations: 40     Fields:    Translation:HumansAnimals
  122. Salthouse CD, Weissleder R, Mahmood U. Development of a time domain fluorimeter for fluorescent lifetime multiplexing analysis. IEEE Trans Biomed Circuits Syst. 2008 Sep 01; 2(3):204-11. PMID: 19830273.
    Citations: 2     Fields:    
  123. Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U. Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy. Radiology. 2008 Sep; 248(3):925-35. PMID: 18647846; PMCID: PMC2798096.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  124. Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U. In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008 Jul; 1(2):84-94. PMID: 18633456.
    Citations: 13     
  125. Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R. Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. PLoS Med. 2008 Apr 15; 5(4):e85. PMID: 18416599.
    Citations: 102     Fields:    Translation:HumansAnimalsCells
  126. Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U. Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer. 2007 Dec 01; 121(11):2492-500. PMID: 17683072.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  127. Upadhyay R, Sheth RA, Weissleder R, Mahmood U. Quantitative real-time catheter-based fluorescence molecular imaging in mice. Radiology. 2007 Nov; 245(2):523-31. PMID: 17940307.
    Citations: 27     Fields:    Translation:Animals
  128. Kozloff KM, Weissleder R, Mahmood U. Noninvasive optical detection of bone mineral. J Bone Miner Res. 2007 Aug; 22(8):1208-16. PMID: 17488196.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  129. Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K. Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo. Cancer Res. 2007 Aug 01; 67(15):7335-42. PMID: 17671203.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  130. Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D. Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. J Exp Med. 2007 Aug 06; 204(8):1911-22. PMID: 17646407; PMCID: PMC2118664.
    Citations: 39     Fields:    Translation:AnimalsCells
  131. Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U. Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007 Jul-Aug; 6(4):269-76. PMID: 17711782.
    Citations: 13     Fields:    Translation:AnimalsCells
  132. Mahmood U, Upadhyay R. Current and Future Imaging Paradigms in Colorectal Cancer. Semin Colon Rectal Surg. 2007 Jun; 18(2):132-138. PMID: 18516215.
    Citations:    
  133. Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U. Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice. Radiology. 2007 Jul; 244(1):232-8. PMID: 17507718.
    Citations: 44     Fields:    Translation:AnimalsCells
  134. Sheth RA, Upadhyay R, Weissleder R, Mahmood U. Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging. 2007 May-Jun; 6(3):147-55. PMID: 17532881.
    Citations: 12     Fields:    Translation:Animals
  135. Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R. Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology. 2007 Mar; 242(3):751-8. PMID: 17325064.
    Citations: 47     Fields:    Translation:AnimalsCells
  136. Mahmood U, Wallace MB. Molecular imaging in gastrointestinal disease. Gastroenterology. 2007 Jan; 132(1):11-4. PMID: 17241854.
    Citations: 10     Fields:    Translation:HumansAnimals
  137. Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B. Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arthritis Rheum. 2007 Jan; 56(1):117-28. PMID: 17195214.
    Citations: 19     Fields:    Translation:AnimalsCells
  138. Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U. Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization. Gastrointest Endosc. 2006 Oct; 64(4):589-97. PMID: 16996355.
    Citations: 29     Fields:    Translation:Animals
  139. Kozloff KM, Quinti L, Tung C, Weissleder R, Mahmood U. Non-invasive imaging of osteoclast activity via near-infrared cathepsin-K activatable optical probe. J Musculoskelet Neuronal Interact. 2006 Oct-Dec; 6(4):353. PMID: 17185820.
    Citations: 2     Fields:    Translation:AnimalsCells
  140. Mahmood U. Can a clinically used chemoembolization vehicle improve transgene delivery? Radiology. 2006 Sep; 240(3):619-20. PMID: 16926318.
    Citations:    Fields:    Translation:HumansAnimals
  141. Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL. In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice. Neoplasia. 2006 Sep; 8(9):772-80. PMID: 16984734.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  142. Figueiredo JL, Alencar H, Weissleder R, Mahmood U. Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer. Int J Cancer. 2006 Jun 01; 118(11):2672-7. PMID: 16380983.
    Citations: 26     Fields:    Translation:HumansAnimals
  143. Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK. N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption. Mol Cell Biol. 2006 Jun; 26(11):4185-200. PMID: 16705170; PMCID: PMC1489079.
    Citations: 13     Fields:    Translation:AnimalsCells
  144. Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Jänne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK. The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell. 2006 Jun; 9(6):485-95. PMID: 16730237.
    Citations: 181     Fields:    Translation:HumansAnimalsCells
  145. Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A. 2006 Apr 11; 103(15):5947-52. PMID: 16585505; PMCID: PMC1458678.
    Citations: 297     Fields:    Translation:Animals
  146. Tréhin R, Figueiredo JL, Pittet MJ, Weissleder R, Josephson L, Mahmood U. Fluorescent nanoparticle uptake for brain tumor visualization. Neoplasia. 2006 Apr; 8(4):302-11. PMID: 16756722.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  147. Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C. Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006 Mar; 7(3):284-92. PMID: 16444258.
    Citations: 87     Fields:    Translation:AnimalsCells
  148. Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC. Identification of the target self-antigens in reperfusion injury. J Exp Med. 2006 Jan 23; 203(1):141-52. PMID: 16390934; PMCID: PMC2118091.
    Citations: 98     Fields:    Translation:Animals
  149. Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R,