Harvard Catalyst Profiles

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Herminia Diana Rosas, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01NS106384 (ROSAS, HERMINIA DIANA) Sep 15, 2018 - Jun 30, 2023
    NIH/NINDS
    Huntington's disease: Learning from Extremes
    Role: Principal Investigator
  2. R21NS098407 (ROSAS, HERMINIA DIANA) Apr 1, 2017 - Mar 31, 2019
    NIH/NINDS
    Using PET to Map Epigenetic Changes in Huntington's Disease.
    Role: Principal Investigator
  3. R21NS081409 (ROSAS, HERMINIA DIANA) Jul 1, 2013 - Jun 30, 2015
    NIH/NINDS
    Using High Field MRI to Evaluate Metal Dyshomeostasis in Huntington???s Disease
    Role: Principal Investigator
  4. P01NS058793 (HERSCH, STEVEN M) Jun 9, 2008 - Feb 28, 2014
    NIH/NINDS
    Biomarkers for Huntington's Disease: Accelerating the Development of Therapies
    Role: Co-Principal Investigator
  5. R56NS042861 (ROSAS, HERMINIA DIANA) Dec 1, 2001 - Aug 31, 2015
    NIH/NINDS
    Prospective Neuroimaging in Huntington's Disease
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lois C, González I, Izquierdo-García D, Zürcher NR, Wilkens P, Loggia ML, Hooker JM, Rosas HD. Neuroinflammation in Huntington's Disease: New Insights with 11C-PBR28 PET/MRI. ACS Chem Neurosci. 2018 Nov 21; 9(11):2563-2571. PMID: 29719953.
    Citations:    Fields:    
  2. Stephen CD, Hung J, Schifitto G, Hersch SM, Rosas HD. Electrocardiogram Abnormalities Suggest Aberrant Cardiac Conduction in Huntington's Disease. Mov Disord Clin Pract. 2018 May-Jun; 5(3):306-311. PMID: 30363459.
    Citations:    
  3. Rosas HD, Wilkens P, Salat DH, Mercaldo ND, Vangel M, Yendiki AY, Hersch SM. Complex spatial and temporally defined myelin and axonal degeneration in Huntington disease. Neuroimage Clin. 2018; 20:236-242. PMID: 30090698.
    Citations:    Fields:    Translation:HumansCells
  4. Hersch SM, Schifitto G, Oakes D, Bredlau AL, Meyers CM, Nahin R, Rosas HD. The CREST-E study of creatine for Huntington disease: A randomized controlled trial. Neurology. 2017 Aug 08; 89(6):594-601. PMID: 28701493.
    Citations: 6     Fields:    Translation:Humans
  5. McGarry A, McDermott M, Kieburtz K, de Blieck EA, Beal F, Marder K, Ross C, Shoulson I, Gilbert P, Mallonee WM, Guttman M, Wojcieszek J, Kumar R, LeDoux MS, Jenkins M, Rosas HD, Nance M, Biglan K, Como P, Dubinsky RM, Shannon KM, O'Suilleabhain P, Chou K, Walker F, Martin W, Wheelock VL, McCusker E, Jankovic J, Singer C, Sanchez-Ramos J, Scott B, Suchowersky O, Factor SA, Higgins DS, Molho E, Revilla F, Caviness JN, Friedman JH, Perlmutter JS, Feigin A, Anderson K, Rodriguez R, McFarland NR, Margolis RL, Farbman ES, Raymond LA, Suski V, Kostyk S, Colcher A, Seeberger L, Epping E, Esmail S, Diaz N, Fung WL, Diamond A, Frank S, Hanna P, Hermanowicz N, Dure LS, Cudkowicz M. A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease. Neurology. 2017 Jan 10; 88(2):152-159. PMID: 27913695.
    Citations: 9     Fields:    Translation:Humans
  6. Coutinho AM, Coutu JP, Lindemer ER, Rosas HD, Rosen BR, Salat DH. Differential associations between systemic markers of disease and cortical thickness in healthy middle-aged and older adults. Neuroimage. 2017 02 01; 146:19-27. PMID: 27847345.
    Citations:    Fields:    Translation:Humans
  7. Nasr S, Rosas HD. Impact of Visual Corticostriatal Loop Disruption on Neural Processing within the Parahippocampal Place Area. J Neurosci. 2016 10 05; 36(40):10456-10471. PMID: 27707978.
    Citations:    Fields:    Translation:Humans
  8. Ryu CW, Coutu JP, Greka A, Rosas HD, Jahng GH, Rosen BR, Salat DH. Differential associations between systemic markers of disease and white matter tissue health in middle-aged and older adults. J Cereb Blood Flow Metab. 2017 Nov; 37(11):3568-3579. PMID: 27298238.
    Citations: 1     Fields:    Translation:HumansCells
  9. Coutu JP, Goldblatt A, Rosas HD, Salat DH. White Matter Changes are Associated with Ventricular Expansion in Aging, Mild Cognitive Impairment, and Alzheimer's Disease. J Alzheimers Dis. 2016; 49(2):329-42. PMID: 26444767.
    Citations: 5     Fields:    Translation:Humans
  10. Yendiki A, Reuter M, Wilkens P, Rosas HD, Fischl B. Joint reconstruction of white-matter pathways from longitudinal diffusion MRI data with anatomical priors. Neuroimage. 2016 Feb 15; 127:277-286. PMID: 26717853.
    Citations: 3     Fields:    Translation:Humans
  11. Pickhardt PJ, Lauder T, Pooler BD, Muñoz Del Rio A, Rosas H, Bruce RJ, Binkley N. Effect of IV contrast on lumbar trabecular attenuation at routine abdominal CT: correlation with DXA and implications for opportunistic osteoporosis screening. Osteoporos Int. 2016 Jan; 27(1):147-52. PMID: 26153046.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  12. Rosas HD, Doros G, Bhasin S, Thomas B, Gevorkian S, Malarick K, Matson W, Hersch SM. A systems-level "misunderstanding": the plasma metabolome in Huntington's disease. Ann Clin Transl Neurol. 2015 Jul; 2(7):756-68. PMID: 26273688.
    Citations: 4     
  13. Lee SH, Coutu JP, Wilkens P, Yendiki A, Rosas HD, Salat DH. Tract-based analysis of white matter degeneration in Alzheimer's disease. Neuroscience. 2015 Aug 20; 301:79-89. PMID: 26026680.
    Citations: 12     Fields:    Translation:Humans
  14. Narayanan KL, Chopra V, Rosas HD, Malarick K, Hersch S. Rho Kinase Pathway Alterations in the Brain and Leukocytes in Huntington's Disease. Mol Neurobiol. 2016 May; 53(4):2132-40. PMID: 25941073.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  15. Ryu SY, Coutu JP, Rosas HD, Salat DH. Effects of insulin resistance on white matter microstructure in middle-aged and older adults. Neurology. 2014 May 27; 82(21):1862-70. PMID: 24771537.
    Citations: 5     Fields:    Translation:HumansCells
  16. Rosas HD, Doros G, Gevorkian S, Malarick K, Reuter M, Coutu JP, Triggs TD, Wilkens PJ, Matson W, Salat DH, Hersch SM. PRECREST: a phase II prevention and biomarker trial of creatine in at-risk Huntington disease. Neurology. 2014 Mar 11; 82(10):850-7. PMID: 24510496.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  17. Coutu JP, Chen JJ, Rosas HD, Salat DH. Non-Gaussian water diffusion in aging white matter. Neurobiol Aging. 2014 Jun; 35(6):1412-21. PMID: 24378085.
    Citations: 13     Fields:    Translation:Humans
  18. Moscovitch-Lopatin M, Goodman RE, Eberly S, Ritch JJ, Rosas HD, Matson S, Matson W, Oakes D, Young AB, Shoulson I, Hersch SM. HTRF analysis of soluble huntingtin in PHAROS PBMCs. Neurology. 2013 Sep 24; 81(13):1134-40. PMID: 23966247.
    Citations: 1     Fields:    Translation:HumansCells
  19. Ramos EM, Latourelle JC, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Gellera C, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Gusella JF, Lee JM, Alonso I, Sequeiros J, Myers RH, Macdonald ME. Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset. Neurogenetics. 2013 Nov; 14(3-4):173-9. PMID: 23644918.
    Citations: 3     Fields:    Translation:Humans
  20. Chen JJ, Rosas HD, Salat DH. The relationship between cortical blood flow and sub-cortical white-matter health across the adult age span. PLoS One. 2013; 8(2):e56733. PMID: 23437228.
    Citations: 18     Fields:    Translation:HumansCells
  21. Thomas B, Matson S, Chopra V, Sun L, Sharma S, Hersch S, Rosas HD, Scherzer C, Ferrante R, Matson W. A novel method for detecting 7-methyl guanine reveals aberrant methylation levels in Huntington disease. Anal Biochem. 2013 May 15; 436(2):112-20. PMID: 23416183.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  22. Ramos EM, Latourelle JC, Lee JH, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Marder K, Gusella JF, Lee JM, Alonso I, Sequeiros J, Myers RH, Macdonald ME. Population stratification may bias analysis of PGC-1a as a modifier of age at Huntington disease motor onset. Hum Genet. 2012 Dec; 131(12):1833-40. PMID: 22825315.
    Citations: 10     Fields:    Translation:HumansCells
  23. Lee JH, Lee JM, Ramos EM, Gillis T, Mysore JS, Kishikawa S, Hadzi T, Hendricks AE, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Gellera C, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, Landwehrmeyer GB, Shoulson I, Myers RH, MacDonald ME, Gusella JF. TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington's disease. Biochem Biophys Res Commun. 2012 Aug 03; 424(3):404-8. PMID: 22771793.
    Citations: 4     Fields:    Translation:HumansCells
  24. Rosas HD, Chen YI, Doros G, Salat DH, Chen NK, Kwong KK, Bush A, Fox J, Hersch SM. Alterations in brain transition metals in Huntington disease: an evolving and intricate story. Arch Neurol. 2012 Jul; 69(7):887-93. PMID: 22393169.
    Citations: 24     Fields:    Translation:Humans
  25. Reuter M, Schmansky NJ, Rosas HD, Fischl B. Within-subject template estimation for unbiased longitudinal image analysis. Neuroimage. 2012 Jul 16; 61(4):1402-18. PMID: 22430496.
    Citations: 346     Fields:    Translation:Humans
  26. Lee JM, Gillis T, Mysore JS, Ramos EM, Myers RH, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Griguoli A, Di Donato S, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, MacDonald ME, Gusella JF. Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. Am J Hum Genet. 2012 Mar 09; 90(3):434-44. PMID: 22387017.
    Citations: 20     Fields:    Translation:HumansCells
  27. Lee JM, Ramos EM, Lee JH, Gillis T, Mysore JS, Hayden MR, Warby SC, Morrison P, Nance M, Ross CA, Margolis RL, Squitieri F, Orobello S, Di Donato S, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, Paulsen JS, Landwehrmeyer GB, Myers RH, MacDonald ME, Gusella JF. CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. Neurology. 2012 Mar 06; 78(10):690-5. PMID: 22323755.
    Citations: 79     Fields:    Translation:HumansCells
  28. Hu Y, Chopra V, Chopra R, Locascio JJ, Liao Z, Ding H, Zheng B, Matson WR, Ferrante RJ, Rosas HD, Hersch SM, Scherzer CR. Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse. Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):17141-6. PMID: 21969577.
    Citations: 28     Fields:    Translation:HumansAnimalsCTClinical Trials
  29. Chen JJ, Salat DH, Rosas HD. Complex relationships between cerebral blood flow and brain atrophy in early Huntington's disease. Neuroimage. 2012 Jan 16; 59(2):1043-51. PMID: 21945790.
    Citations: 10     Fields:    Translation:Humans
  30. Rosas HD, Reuter M, Doros G, Lee SY, Triggs T, Malarick K, Fischl B, Salat DH, Hersch SM. A tale of two factors: what determines the rate of progression in Huntington's disease? A longitudinal MRI study. Mov Disord. 2011 Aug 01; 26(9):1691-7. PMID: 21611979.
    Citations: 12     Fields:    Translation:HumansCells
  31. Moscovitch-Lopatin M, Weiss A, Rosas HD, Ritch J, Doros G, Kegel KB, Difiglia M, Kuhn R, Bilbe G, Paganetti P, Hersch S. Optimization of an HTRF Assay for the Detection of Soluble Mutant Huntingtin in Human Buffy Coats: A Potential Biomarker in Blood for Huntington Disease. PLoS Curr. 2010 Dec 29; 2:RRN1205. PMID: 21278900.
    Citations: 6     
  32. Chen JJ, Rosas HD, Salat DH. Age-associated reductions in cerebral blood flow are independent from regional atrophy. Neuroimage. 2011 Mar 15; 55(2):468-78. PMID: 21167947.
    Citations: 76     Fields:    Translation:Humans
  33. Weiss A, Grueninger S, Abramowski D, Giorgio FP, Lopatin MM, Rosas HD, Hersch S, Paganetti P. Microtiter plate quantification of mutant and wild-type huntingtin normalized to cell count. Anal Biochem. 2011 Mar 15; 410(2):304-6. PMID: 21134349.
    Citations: 8     Fields:    Translation:HumansCells
  34. Bechtel N, Scahill RI, Rosas HD, Acharya T, van den Bogaard SJ, Jauffret C, Say MJ, Sturrock A, Johnson H, Onorato CE, Salat DH, Durr A, Leavitt BR, Roos RA, Landwehrmeyer GB, Langbehn DR, Stout JC, Tabrizi SJ, Reilmann R. Tapping linked to function and structure in premanifest and symptomatic Huntington disease. Neurology. 2010 Dec 14; 75(24):2150-60. PMID: 21068430.
    Citations: 28     Fields:    Translation:HumansCells
  35. Salat DH, Chen JJ, van der Kouwe AJ, Greve DN, Fischl B, Rosas HD. Hippocampal degeneration is associated with temporal and limbic gray matter/white matter tissue contrast in Alzheimer's disease. Neuroimage. 2011 Feb 01; 54(3):1795-802. PMID: 20965261.
    Citations: 18     Fields:    Translation:HumansCells
  36. Reuter M, Rosas HD, Fischl B. Highly accurate inverse consistent registration: a robust approach. Neuroimage. 2010 Dec; 53(4):1181-96. PMID: 20637289.
    Citations: 213     Fields:    Translation:Humans
  37. Kim J, Amante DJ, Moody JP, Edgerly CK, Bordiuk OL, Smith K, Matson SA, Matson WR, Scherzer CR, Rosas HD, Hersch SM, Ferrante RJ. Reduced creatine kinase as a central and peripheral biomarker in Huntington's disease. Biochim Biophys Acta. 2010 Jul-Aug; 1802(7-8):673-81. PMID: 20460152.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  38. Salat DH, Tuch DS, van der Kouwe AJ, Greve DN, Pappu V, Lee SY, Hevelone ND, Zaleta AK, Growdon JH, Corkin S, Fischl B, Rosas HD. White matter pathology isolates the hippocampal formation in Alzheimer's disease. Neurobiol Aging. 2010 Feb; 31(2):244-56. PMID: 18455835.
    Citations: 98     Fields:    Translation:HumansCells
  39. Rosas HD, Lee SY, Bender AC, Zaleta AK, Vangel M, Yu P, Fischl B, Pappu V, Onorato C, Cha JH, Salat DH, Hersch SM. Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection". Neuroimage. 2010 Feb 15; 49(4):2995-3004. PMID: 19850138.
    Citations: 69     Fields:    Translation:HumansCells
  40. Weiss A, Abramowski D, Bibel M, Bodner R, Chopra V, DiFiglia M, Fox J, Kegel K, Klein C, Grueninger S, Hersch S, Housman D, Régulier E, Rosas HD, Stefani M, Zeitlin S, Bilbe G, Paganetti P. Single-step detection of mutant huntingtin in animal and human tissues: a bioassay for Huntington's disease. Anal Biochem. 2009 Dec 01; 395(1):8-15. PMID: 19664996.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  41. Tabrizi SJ, Langbehn DR, Leavitt BR, Roos RA, Durr A, Craufurd D, Kennard C, Hicks SL, Fox NC, Scahill RI, Borowsky B, Tobin AJ, Rosas HD, Johnson H, Reilmann R, Landwehrmeyer B, Stout JC. Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data. Lancet Neurol. 2009 Sep; 8(9):791-801. PMID: 19646924.
    Citations: 194     Fields:    Translation:HumansCTClinical Trials
  42. Salat DH, Lee SY, van der Kouwe AJ, Greve DN, Fischl B, Rosas HD. Age-associated alterations in cortical gray and white matter signal intensity and gray to white matter contrast. Neuroimage. 2009 Oct 15; 48(1):21-8. PMID: 19580876.
    Citations: 65     Fields:    Translation:HumansCells
  43. Brocklebank D, Gayán J, Andresen JM, Roberts SA, Young AB, Snodgrass SR, Penney JB, Ramos-Arroyo MA, Cha JJ, Rosas HD, Hersch SM, Feigin A, Cherny SS, Wexler NS, Housman DE, Cardon LR. Repeat instability in the 27-39 CAG range of the HD gene in the Venezuelan kindreds: Counseling implications. Am J Med Genet B Neuropsychiatr Genet. 2009 Apr 05; 150B(3):425-9. PMID: 18712713.
    Citations: 4     Fields:    Translation:HumansCells
  44. Rosas HD, Salat DH, Lee SY, Zaleta AK, Hevelone N, Hersch SM. Complexity and heterogeneity: what drives the ever-changing brain in Huntington's disease? Ann N Y Acad Sci. 2008 Dec; 1147:196-205. PMID: 19076442.
    Citations: 14     Fields:    Translation:Humans
  45. Liu W, Kennington LA, Rosas HD, Hersch S, Cha JH, Zamore PD, Aronin N. Linking SNPs to CAG repeat length in Huntington's disease patients. Nat Methods. 2008 Nov; 5(11):951-3. PMID: 18931668.
    Citations: 16     Fields:    Translation:HumansCells
  46. Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RL. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cereb Cortex. 2009 Mar; 19(3):497-510. PMID: 18632739.
    Citations: 237     Fields:    Translation:Humans
  47. Nectoux J, Bahi-Buisson N, Guellec I, Coste J, De Roux N, Rosas H, Tardieu M, Chelly J, Bienvenu T. The p.Val66Met polymorphism in the BDNF gene protects against early seizures in Rett syndrome. Neurology. 2008 May 27; 70(22 Pt 2):2145-51. PMID: 18434641.
    Citations: 12     Fields:    Translation:Humans
  48. Hersch SM, Rosas HD. Neuroprotection for Huntington's disease: ready, set, slow. Neurotherapeutics. 2008 Apr; 5(2):226-36. PMID: 18394565.
    Citations: 11     Fields:    Translation:Humans
  49. Rosas HD, Salat DH, Lee SY, Zaleta AK, Pappu V, Fischl B, Greve D, Hevelone N, Hersch SM. Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity. Brain. 2008 Apr; 131(Pt 4):1057-68. PMID: 18337273.
    Citations: 110     Fields:    Translation:Humans
  50. Hinds O, Polimeni JR, Rajendran N, Balasubramanian M, Wald LL, Augustinack JC, Wiggins G, Rosas HD, Fischl B, Schwartz EL. The intrinsic shape of human and macaque primary visual cortex. Cereb Cortex. 2008 Nov; 18(11):2586-95. PMID: 18308709.
    Citations: 13     Fields:    Translation:HumansAnimals
  51. Grodstein F, van Oijen M, Irizarry MC, Rosas HD, Hyman BT, Growdon JH, De Vivo I. Shorter telomeres may mark early risk of dementia: preliminary analysis of 62 participants from the nurses' health study. PLoS One. 2008 Feb 13; 3(2):e1590. PMID: 18795148.
    Citations: 33     Fields:    Translation:HumansCells
  52. Rosas HD, Tuch DS, Hevelone ND, Zaleta AK, Vangel M, Hersch SM, Salat DH. Diffusion tensor imaging in presymptomatic and early Huntington's disease: Selective white matter pathology and its relationship to clinical measures. Mov Disord. 2006 Sep; 21(9):1317-25. PMID: 16755582.
    Citations: 92     Fields:    Translation:HumansCells
  53. Salat DH, Smith EE, Tuch DS, Benner T, Pappu V, Schwab KM, Gurol ME, Rosas HD, Rosand J, Greenberg SM. White matter alterations in cerebral amyloid angiopathy measured by diffusion tensor imaging. Stroke. 2006 Jul; 37(7):1759-64. PMID: 16763176.
    Citations: 20     Fields:    Translation:Humans
  54. Hersch SM, Gevorkian S, Marder K, Moskowitz C, Feigin A, Cox M, Como P, Zimmerman C, Lin M, Zhang L, Ulug AM, Beal MF, Matson W, Bogdanov M, Ebbel E, Zaleta A, Kaneko Y, Jenkins B, Hevelone N, Zhang H, Yu H, Schoenfeld D, Ferrante R, Rosas HD. Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG. Neurology. 2006 Jan 24; 66(2):250-2. PMID: 16434666.
    Citations: 77     Fields:    Translation:Humans
  55. Salat DH, Tuch DS, Hevelone ND, Fischl B, Corkin S, Rosas HD, Dale AM. Age-related changes in prefrontal white matter measured by diffusion tensor imaging. Ann N Y Acad Sci. 2005 Dec; 1064:37-49. PMID: 16394146.
    Citations: 108     Fields:    Translation:HumansCells
  56. Rosas HD, Hevelone ND, Zaleta AK, Greve DN, Salat DH, Fischl B. Regional cortical thinning in preclinical Huntington disease and its relationship to cognition. Neurology. 2005 Sep 13; 65(5):745-7. PMID: 16157910.
    Citations: 79     Fields:    Translation:HumansCells
  57. Tuch DS, Salat DH, Wisco JJ, Zaleta AK, Hevelone ND, Rosas HD. Choice reaction time performance correlates with diffusion anisotropy in white matter pathways supporting visuospatial attention. Proc Natl Acad Sci U S A. 2005 Aug 23; 102(34):12212-7. PMID: 16103359.
    Citations: 81     Fields:    Translation:Humans
  58. Ryu H, Rosas HD, Hersch SM, Ferrante RJ. The therapeutic role of creatine in Huntington's disease. Pharmacol Ther. 2005 Nov; 108(2):193-207. PMID: 16055197.
    Citations: 14     Fields:    Translation:HumansAnimals
  59. Borovecki F, Lovrecic L, Zhou J, Jeong H, Then F, Rosas HD, Hersch SM, Hogarth P, Bouzou B, Jensen RV, Krainc D. Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):11023-8. PMID: 16043692.
    Citations: 130     Fields:    Translation:HumansCells
  60. Hogarth P, Kayson E, Kieburtz K, Marder K, Oakes D, Rosas D, Shoulson I, Wexler N, Young AB, Zhao H. A study of inter-rater reliability of the motor diagnosis of Huntington’s disease. Movement Disorders. 2005; Dec 6(xx):xx.
  61. Salat DH, Tuch DS, Greve DN, van der Kouwe AJ, Hevelone ND, Zaleta AK, Rosen BR, Fischl B, Corkin S, Rosas HD, Dale AM. Age-related alterations in white matter microstructure measured by diffusion tensor imaging. Neurobiol Aging. 2005 Aug-Sep; 26(8):1215-27. PMID: 15917106.
    Citations: 241     Fields:    Translation:HumansCells
  62. Rosas HD, Feigin AS, Hersch SM. Using advances in neuroimaging to detect, understand, and monitor disease progression in Huntington's disease. NeuroRx. 2004 Apr; 1(2):263-72. PMID: 15717027.
    Citations: 16     Fields:    Translation:Humans
  63. The US-Venezuela Collaborative Research Project . Venezuelan kindreds reveal that genetic and environmental factors modulate Huntingotn’s disease age of onset. Proc Natl Aca Sci USA. 2004; 101(10):3498-503.
  64. Rosas HD, Koroshetz WJ, Chen YI, Skeuse C, Vangel M, Cudkowicz ME, Caplan K, Marek K, Seidman LJ, Makris N, Jenkins BG, Goldstein JM. Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis. Neurology. 2003 May 27; 60(10):1615-20. PMID: 12771251.
    Citations: 98     Fields:    Translation:Humans
  65. Rosas HD, Liu AK, Hersch S, Glessner M, Ferrante RJ, Salat DH, van der Kouwe A, Jenkins BG, Dale AM, Fischl B. Regional and progressive thinning of the cortical ribbon in Huntington's disease. Neurology. 2002 Mar 12; 58(5):695-701. PMID: 11889230.
    Citations: 288     Fields:    Translation:Humans
  66. Sperling R, Greve D, Dale A, Killiany R, Holmes J, Rosas HD, Cocchiarella A, Firth P, Rosen B, Lake S, Lange N, Routledge C, Albert M. Functional MRI detection of pharmacologically induced memory impairment. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):455-60. PMID: 11756667.
    Citations: 54     Fields:    Translation:Humans
  67. Hersch SM, Rosas HD. 10 most commonly asked questions about Huntington's disease. Neurologist. 2001 Nov; 7(6):364-8. PMID: 14649632.
    Citations:    Fields:    
  68. Rosas HD, Goodman J, Chen YI, Jenkins BG, Kennedy DN, Makris N, Patti M, Seidman LJ, Beal MF, Koroshetz WJ. Striatal volume loss in HD as measured by MRI and the influence of CAG repeat. Neurology. 2001 Sep 25; 57(6):1025-8. PMID: 11571328.
    Citations: 44     Fields:    Translation:HumansCells
  69. Hersch SM, Rosas HD. Neuroprotective therapy for Huntington's disease: new prospects and challenges. Expert Rev Neurother. 2001 Sep; 1(1):111-8. PMID: 19811052.
    Citations:    Fields:    
  70. Rosas HD, Koroshetz WJ, Jenkins BG, Chen YI, Hayden DL, Beal MF, Cudkowicz ME. Riluzole therapy in Huntington's disease (HD). Mov Disord. 1999 Mar; 14(2):326-30. PMID: 10091628.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  71. Jenkins BG, Chen YI, Kuestermann E, Makris NM, Nguyen TV, Kraft E, Brownell AL, Rosas HD, Kennedy DN, Rosen BR, Koroshetz WJ, Beal MF. An integrated strategy for evaluation of metabolic and oxidative defects in neurodegenerative illness using magnetic resonance techniques. Ann N Y Acad Sci. 1999; 893:214-42. PMID: 10672240.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  72. Counter SA, Buchanan LH, Rosas HD, Ortega F. Neurocognitive effects of chronic lead intoxication in Andean children. J Neurol Sci. 1998 Sep 18; 160(1):47-53. PMID: 9804116.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  73. Jenkins BG, Rosas HD, Chen YC, Makabe T, Myers R, MacDonald M, Rosen BR, Beal MF, Koroshetz WJ. 1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers. Neurology. 1998 May; 50(5):1357-65. PMID: 9595987.
    Citations: 42     Fields:    Translation:HumansCells
  74. Carter BS, Ogilvy CS, Candia GJ, Rosas HD, Buonanno F. One-year outcome after decompressive surgery for massive nondominant hemispheric infarction. Neurosurgery. 1997 Jun; 40(6):1168-75; discussion 1175-6. PMID: 9179889.
    Citations: 36     Fields:    Translation:Humans
  75. Cher LM, Hochberg FH, Teruya J, Nitschke M, Valenzuela RF, Schmahmann JD, Herbert M, Rosas HD, Stowell C. Therapy for paraneoplastic neurologic syndromes in six patients with protein A column immunoadsorption. Cancer. 1995 Apr 01; 75(7):1678-83. PMID: 8826927.
    Citations: 13     Fields:    Translation:Humans
  76. Ruprecht RM, Gama-Sosa MA, Rosas HD. Combination therapy after retroviral inoculation. Lancet. 1988 Jan 30; 1(8579):239-40. PMID: 2893060.
    Citations: 4     Fields:    Translation:HumansAnimals
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.