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Allegra Adele Petti, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Petti AA, Williams SR, Miller CA, Fiddes IT, Srivatsan SN, Chen DY, Fronick CC, Fulton RS, Church DM, Ley TJ. Author Correction: A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing. Nat Commun. 2022 Jul 21; 13(1):4216. PMID: 35864110; PMCID: PMC9304390.
    Citations:    Fields:    
  2. Wang AZ, Bowman-Kirigin JA, Desai R, Kang LI, Patel PR, Patel B, Khan SM, Bender D, Marlin MC, Liu J, Osbun JW, Leuthardt EC, Chicoine MR, Dacey RG, Zipfel GJ, Kim AH, DeNardo DG, Petti AA, Dunn GP. Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response. Genome Med. 2022 05 10; 14(1):49. PMID: 35534852; PMCID: PMC9088131.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  3. Upadhyay P, Beales J, Shah NM, Gruszczynska A, Miller CA, Petti AA, Ramakrishnan SM, Link DC, Ley TJ, Welch JS. Recurrent transcriptional responses in AML and MDS patients treated with decitabine. Exp Hematol. 2022 07; 111:50-65. PMID: 35429619.
    Citations:    Fields:    Translation:Humans
  4. Bednarski JJ, Zimmerman C, Berrien-Elliott MM, Foltz JA, Becker-Hapak M, Neal CC, Foster M, Schappe T, McClain E, Pence PP, Desai S, Kersting-Schadek S, Wong P, Russler-Germain DA, Fisk B, Lie WR, Eisele J, Hyde S, Bhatt ST, Griffith OL, Griffith M, Petti AA, Cashen AF, Fehniger TA. Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant. Blood. 2022 03 17; 139(11):1670-1683. PMID: 34871371; PMCID: PMC8931511.
    Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
  5. Berrien-Elliott MM, Foltz JA, Russler-Germain DA, Neal CC, Tran J, Gang M, Wong P, Fisk B, Cubitt CC, Marin ND, Zhou AY, Jacobs MT, Foster M, Schappe T, McClain E, Kersting-Schadek S, Desai S, Pence P, Becker-Hapak M, Eisele J, Mosior M, Marsala L, Griffith OL, Griffith M, Khan SM, Spencer DH, DiPersio JF, Romee R, Uy GL, Abboud CN, Ghobadi A, Westervelt P, Stockerl-Goldstein K, Schroeder MA, Wan F, Lie WR, Soon-Shiong P, Petti AA, Cashen AF, Fehniger TA. Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia. Sci Transl Med. 2022 02 23; 14(633):eabm1375. PMID: 35196021; PMCID: PMC9210521.
    Citations: 2     Fields:    Translation:HumansCells
  6. Mahlokozera T, Patel B, Chen H, Desouza P, Qu X, Mao DD, Hafez D, Yang W, Taiwo R, Paturu M, Salehi A, Gujar AD, Dunn GP, Mosammaparast N, Petti AA, Yano H, Kim AH. Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma. Nat Commun. 2021 11 03; 12(1):6321. PMID: 34732716; PMCID: PMC8566473.
    Citations:    Fields:    Translation:HumansAnimalsCells
  7. Petti AA, Khan SM, Xu Z, Helton N, Fronick CC, Fulton R, Ramakrishnan SM, Nonavinkere Srivatsan S, Heath SE, Westervelt P, Payton JE, Walter MJ, Link DC, DiPersio J, Miller C, Ley TJ. Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia. Blood Cancer Discov. 2022 01; 3(1):32-49. PMID: 35019859.
    Citations: 2     Fields:    Translation:Humans
  8. Foltz JA, Hess BT, Bachanova V, Bartlett NL, Berrien-Elliott MM, McClain E, Becker-Hapak M, Foster M, Schappe T, Kahl B, Mehta-Shah N, Cashen AF, Marin ND, McDaniels K, Moreno C, Mosior M, Gao F, Griffith OL, Griffith M, Wagner JA, Epperla N, Rock AD, Lee J, Petti AA, Soon-Shiong P, Fehniger TA. Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma. Clin Cancer Res. 2021 06 15; 27(12):3339-3350. PMID: 33832946; PMCID: PMC8197753.
    Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
  9. Ketkar S, Verdoni AM, Smith AM, Bangert CV, Leight ER, Chen DY, Brune MK, Helton NM, Hoock M, George DR, Fronick C, Fulton RS, Ramakrishnan SM, Chang GS, Petti AA, Spencer DH, Miller CA, Ley TJ. Remethylation of Dnmt3a-/- hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing. Proc Natl Acad Sci U S A. 2020 02 11; 117(6):3123-3134. PMID: 31996479; PMCID: PMC7022185.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  10. Petti AA, Williams SR, Miller CA, Fiddes IT, Srivatsan SN, Chen DY, Fronick CC, Fulton RS, Church DM, Ley TJ. A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing. Nat Commun. 2019 08 14; 10(1):3660. PMID: 31413257; PMCID: PMC6694122.
    Citations: 54     Fields:    Translation:Humans
  11. Christopher MJ, Petti AA, Rettig MP, Miller CA, Chendamarai E, Duncavage EJ, Klco JM, Helton NM, O'Laughlin M, Fronick CC, Fulton RS, Wilson RK, Wartman LD, Welch JS, Heath SE, Baty JD, Payton JE, Graubert TA, Link DC, Walter MJ, Westervelt P, Ley TJ, DiPersio JF. Immune Escape of Relapsed AML Cells after Allogeneic Transplantation. N Engl J Med. 2018 12 13; 379(24):2330-2341. PMID: 30380364; PMCID: PMC6322675.
    Citations: 118     Fields:    Translation:HumansCells
  12. Zhu L, Cheng G, Ye D, Nazeri A, Yue Y, Liu W, Wang X, Dunn GP, Petti AA, Leuthardt EC, Chen H. Focused Ultrasound-enabled Brain Tumor Liquid Biopsy. Sci Rep. 2018 04 26; 8(1):6553. PMID: 29700310; PMCID: PMC5919906.
    Citations: 32     Fields:    Translation:Animals
  13. Cole CB, Russler-Germain DA, Ketkar S, Verdoni AM, Smith AM, Bangert CV, Helton NM, Guo M, Klco JM, O'Laughlin S, Fronick C, Fulton R, Chang GS, Petti AA, Miller CA, Ley TJ. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies. J Clin Invest. 2017 Oct 02; 127(10):3657-3674. PMID: 28872462; PMCID: PMC5617681.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  14. Zhang X, Kim S, Hundal J, Herndon JM, Li S, Petti AA, Soysal SD, Li L, McLellan MD, Hoog J, Primeau T, Myers N, Vickery TL, Sturmoski M, Hagemann IS, Miller CA, Ellis MJ, Mardis ER, Hansen T, Fleming TP, Goedegebuure SP, Gillanders WE. Breast Cancer Neoantigens Can Induce CD8+ T-Cell Responses and Antitumor Immunity. Cancer Immunol Res. 2017 07; 5(7):516-523. PMID: 28619968; PMCID: PMC5647648.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  15. Welch JS, Petti AA, Ley TJ. Decitabine in TP53-Mutated AML. N Engl J Med. 2017 02 23; 376(8):797-8. PMID: 28225682.
    Citations: 11     Fields:    
  16. Duncavage EJ, Uy GL, Petti AA, Miller CA, Lee YS, Tandon B, Gao F, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Jacoby MA, Cashen AF, Wartman LD, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ, Welch JS. Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy. Blood. 2017 03 09; 129(10):1397-1401. PMID: 28082444; PMCID: PMC5345736.
    Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
  17. Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Cashen AF, Schroeder MA, Jacoby MA, Heath SE, Luber K, Janke MR, Hantel A, Khan N, Sukhanova MJ, Knoebel RW, Stock W, Graubert TA, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ. TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes. N Engl J Med. 2016 11 24; 375(21):2023-2036. PMID: 27959731; PMCID: PMC5217532.
    Citations: 274     Fields:    Translation:HumansCTClinical Trials
  18. Li YI, van de Geijn B, Raj A, Knowles DA, Petti AA, Golan D, Gilad Y, Pritchard JK. RNA splicing is a primary link between genetic variation and disease. Science. 2016 Apr 29; 352(6285):600-4. PMID: 27126046; PMCID: PMC5182069.
    Citations: 225     Fields:    Translation:HumansCells
  19. Hundal J, Carreno BM, Petti AA, Linette GP, Griffith OL, Mardis ER, Griffith M. pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens. Genome Med. 2016 Jan 29; 8(1):11. PMID: 26825632; PMCID: PMC4733280.
    Citations: 165     Fields:    Translation:Humans
  20. Wong TN, Miller CA, Klco JM, Petti A, Demeter R, Helton NM, Li T, Fulton RS, Heath SE, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert TA, Wilson RK, Ley TJ, Link DC. Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML. Blood. 2016 Feb 18; 127(7):893-7. PMID: 26631115; PMCID: PMC4760092.
    Citations: 51     Fields:    Translation:HumansCells
  21. Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Helton NM, Duncavage EJ, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, Chang GS, Fulton R, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Larson DE, Kulkarni S, Ozenberger BA, Welch JS, Walter MJ, Graubert TA, Westervelt P, Radich JP, Link DC, Mardis ER, DiPersio JF, Wilson RK, Ley TJ. Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia. JAMA. 2015 Aug 25; 314(8):811-22. PMID: 26305651; PMCID: PMC4621257.
    Citations: 145     Fields:    Translation:Humans
  22. Carreno BM, Magrini V, Becker-Hapak M, Kaabinejadian S, Hundal J, Petti AA, Ly A, Lie WR, Hildebrand WH, Mardis ER, Linette GP. Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells. Science. 2015 May 15; 348(6236):803-8. PMID: 25837513; PMCID: PMC4549796.
    Citations: 558     Fields:    Translation:HumansCellsCTClinical Trials
  23. Stewart CR, Deery WJ, Egan ES, Myles B, Petti AA. The product of SPO1 gene 56 inhibits host cell division during infection of Bacillus subtilis by bacteriophage SPO1. Virology. 2013 Dec; 447(1-2):249-53. PMID: 24210121.
    Citations: 7     Fields:    Translation:Cells
  24. McIsaac RS, Petti AA, Bussemaker HJ, Botstein D. Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway. Mol Biol Cell. 2012 Aug; 23(15):2993-3007. PMID: 22696683; PMCID: PMC3408425.
    Citations: 24     Fields:    Translation:AnimalsCells
  25. Petti AA, McIsaac RS, Ho-Shing O, Bussemaker HJ, Botstein D. Combinatorial control of diverse metabolic and physiological functions by transcriptional regulators of the yeast sulfur assimilation pathway. Mol Biol Cell. 2012 Aug; 23(15):3008-24. PMID: 22696679; PMCID: PMC3408426.
    Citations: 19     Fields:    Translation:Animals
  26. McIsaac RS, Silverman SJ, McClean MN, Gibney PA, Macinskas J, Hickman MJ, Petti AA, Botstein D. Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiae. Mol Biol Cell. 2011 Nov; 22(22):4447-59. PMID: 21965290; PMCID: PMC3216669.
    Citations: 62     Fields:    Translation:AnimalsCells
  27. Hickman MJ, Petti AA, Ho-Shing O, Silverman SJ, McIsaac RS, Lee TA, Botstein D. Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast. Mol Biol Cell. 2011 Nov; 22(21):4192-204. PMID: 21900497; PMCID: PMC3204079.
    Citations: 26     Fields:    Translation:AnimalsCells
  28. Petti AA, Crutchfield CA, Rabinowitz JD, Botstein D. Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function. Proc Natl Acad Sci U S A. 2011 Nov 08; 108(45):E1089-98. PMID: 21734149; PMCID: PMC3215077.
    Citations: 45     Fields:    Translation:AnimalsCells
  29. Silverman SJ, Petti AA, Slavov N, Parsons L, Briehof R, Thiberge SY, Zenklusen D, Gandhi SJ, Larson DR, Singer RH, Botstein D. Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate. Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15):6946-51. PMID: 20335538; PMCID: PMC2872461.
    Citations: 50     Fields:    Translation:Animals
  30. Petti AA, Church GM. A network of transcriptionally coordinated functional modules in Saccharomyces cerevisiae. Genome Res. 2005 Sep; 15(9):1298-306. PMID: 16109970; PMCID: PMC1199545.
    Citations: 13     Fields:    Translation:AnimalsCells
  31. Steffen M, Petti A, Aach J, D'haeseleer P, Church G. Automated modelling of signal transduction networks. BMC Bioinformatics. 2002 Nov 01; 3:34. PMID: 12413400.
    Citations: 78     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.