Harvard Catalyst Profiles

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Kazuhiko Higashioka, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Saiki C, Kashiwado Y, Yokoyama T, Ayano M, Imabayashi K, Kawano S, Higashioka K, Kimoto Y, Fukata M, Mitoma H, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H. Successful transition from intravenous epoprostenol to oral selexipag and inhaled iloprost in a case of severe pulmonary arterial hypertension associated with systemic lupus erythematosus. Mod Rheumatol Case Rep. 2022 06 24; 6(2):183-188. PMID: 35134204.
    Citations: 1     Fields:    Translation:Humans
  2. Higashioka K, Migita R, Ota T, Uchino A, Niiro H. Successful Treatment of Systemic Sclerosis-related Pericarditis with Mycophenolate Mofetil and Low-dose Prednisolone. Intern Med. 2022 Oct 15; 61(20):3125-3130. PMID: 35283383.
    Citations:    Fields:    
  3. Nakano M, Ayano M, Kushimoto K, Kawano S, Higashioka K, Inokuchi S, Mitoma H, Kimoto Y, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H. Association of elevated serum soluble CD226 levels with the disease activity and flares of systemic lupus erythematosus. Sci Rep. 2021 08 09; 11(1):16162. PMID: 34373559; PMCID: PMC8352936.
    Citations:    Fields:    Translation:Humans
  4. Nakano M, Ayano M, Kushimoto K, Kawano S, Higashioka K, Inokuchi S, Mitoma H, Kimoto Y, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H. Increased Proportion of CD226+ B Cells Is Associated With the Disease Activity and Prognosis of Systemic Lupus Erythematosus. Front Immunol. 2021; 12:713225. PMID: 34367178; PMCID: PMC8334729.
    Citations:    Fields:    Translation:HumansCells
  5. Imabayashi K, Ayano M, Higashioka K, Yokoyama K, Yamamoto K, Takayama K, Mitoma H, Kimoto Y, Akahoshi M, Arinobu Y, Akashi K, Horiuchi T, Niiro H. Infliximab for reversible dementia in acute onset of neuro-Behçet's disease: A case report and cytokine analysis. J Neuroimmunol. 2021 08 15; 357:577631. PMID: 34153801.
    Citations:    Fields:    Translation:Humans
  6. Higashioka K, Yoshimura M, Sakuragi T, Ayano M, Kimoto Y, Mitoma H, Ono N, Arinobu Y, Kikukawa M, Yamada H, Horiuchi T, Akashi K, Niiro H. Human PD-1hiCD8+ T Cells Are a Cellular Source of IL-21 in Rheumatoid Arthritis. Front Immunol. 2021; 12:654623. PMID: 33815416; PMCID: PMC8017303.
    Citations: 2     Fields:    Translation:HumansCells
  7. Nakayama T, Yoshimura M, Higashioka K, Miyawaki K, Ota Y, Ayano M, Kimoto Y, Mitoma H, Ono N, Arinobu Y, Kikukawa M, Yamada H, Akashi K, Horiuchi T, Niiro H. Type 1 helper T cells generate CXCL9/10-producing T-bet+ effector B cells potentially involved in the pathogenesis of rheumatoid arthritis. Cell Immunol. 2021 02; 360:104263. PMID: 33387686.
    Citations: 2     Fields:    Translation:HumansCells
  8. Higashioka K, Ota Y, Maehara T, Moriyama M, Ayano M, Mitoma H, Akahoshi M, Arinobu Y, Horiuchi T, Nakamura S, Akashi K, Niiro H. Association of circulating SLAMF7+Tfh1 cells with IgG4 levels in patients with IgG4-related disease. BMC Immunol. 2020 06 01; 21(1):31. PMID: 32487061; PMCID: PMC7268355.
    Citations: 3     Fields:    Translation:HumansCells
  9. Higuchi T, Omata F, Tsuchihashi K, Higashioka K, Koyamada R, Okada S. Current cigarette smoking is a reversible cause of elevated white blood cell count: Cross-sectional and longitudinal studies. Prev Med Rep. 2016 Dec; 4:417-22. PMID: 27583199; PMCID: PMC4995538.
    Citations: 34     
  10. Shima T, Kamezaki K, Higashioka K, Takashima S, Yoshimoto G, Kato K, Muta T, Takenaka K, Iwasaki H, Miyamoto T, Akashi K. Ascites Retention during Mogamulizumab Treatment in a Patient with Adult T-cell Leukemia/lymphoma. Intern Med. 2016; 55(13):1793-6. PMID: 27374686.
    Citations: 1     Fields:    Translation:Humans
  11. Ota Y, Niiro H, Ota S, Ueki N, Tsuzuki H, Nakayama T, Mishima K, Higashioka K, Jabbarzadeh-Tabrizi S, Mitoma H, Akahoshi M, Arinobu Y, Kukita A, Yamada H, Tsukamoto H, Akashi K. Generation mechanism of RANKL(+) effector memory B cells: relevance to the pathogenesis of rheumatoid arthritis. Arthritis Res Ther. 2016 Mar 16; 18:67. PMID: 26980135; PMCID: PMC4793760.
    Citations: 24     Fields:    Translation:HumansCells
  12. Higashioka K, Niiro H, Yoshida K, Oryoji K, Kamada K, Mizuki S, Yokota E. Renal Insufficiency in Concert with Renin-angiotensin-aldosterone Inhibition Is a Major Risk Factor for Hyperkalemia Associated with Low-dose Trimethoprim-sulfamethoxazole in Adults. Intern Med. 2016; 55(5):467-71. PMID: 26935365.
    Citations: 2     Fields:    Translation:Humans
  13. Higashioka K, Yoshida K, Oryoji K, Kamada K, Mizuki S, Tsukamoto H, Yokota E, Akashi K. Successful Treatment of Lupus Cerebrovascular Disease with Mycophenolate Mofetil. Intern Med. 2015; 54(17):2255-9. PMID: 26328657.
    Citations: 1     Fields:    Translation:Humans
  14. Higashioka K, Miyake N, Nishida R, Chong Y, Shimoda S, Shimono N. [Bilateral Granulomatous Renal Masses after Intravesical BCG Therapy for Non-muscle-invasive Bladder Cancer and Carcinoma in Situ of the Upper Urinary Tract: A Case Study]. Kansenshogaku Zasshi. 2015 Jul; 89(4):481-4. PMID: 26554225.
    Citations: 1     Fields:    Translation:HumansCells
  15. Higashioka K, Yoshida K, Oryoji K, Kamada K, Mizuki S, Tsukamoto H, Yokota E, Akashi K. A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements. Case Rep Rheumatol. 2015; 2015:392893. PMID: 26101684; PMCID: PMC4460202.
    Citations: 6     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.